产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TGF乙1单克隆抗体(TB21)
目录 :
MA1-21595
规格 :
100微克
价格 :
美国432
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
TB21
反应物种 :
人类, 小鼠, 大鼠, 牛, 家羊, domestic rabbit
应用 :
免疫印迹, 免疫组化, 中和反应, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 4
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| |
| Bourreau E, Ronet C, Couppie P, Sainte Marie D, Tacchini Cottier F, Launois P. IL-10 producing CD8+ T cells in human infection with Leishmania guyanensis. Microbes Infect. 2007;9:1034-41 pubmed
|
| Kariminia A, Bourreau E, Pascalis H, Couppie P, Sainte Marie D, Tacchini Cottier F, et al. Transforming growth factor beta 1 production by CD4+ CD25+ regulatory T cells in peripheral blood mononuclear cells from healthy subjects stimulated with Leishmania guyanensis. Infect Immun. 2005;73:5908-14 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
TGF乙1单克隆抗体(TB21)
目录# :
MA1-21595
规格 :
100微克
定价 :
美国432
克隆性 :
单克隆
纯度 :
IgG分馏成分, 蛋白质G
宿主 :
小鼠
反应物种 :
Bovine, Human, Mink, Mouse, Mustelid, Ovine, Rabbit, Rat
应用 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Frozen): 1:1,000, Immunohistochemistry (Paraffin): Assay-dependent, Neutralization: Assay-dependent, Western Blot: 5-20 ng/mL
物种 :
Bovine, Human, Mink, Mouse, Mustelid, Ovine, Rabbit, Rat
克隆 :
TB21
抗体亚型 :
IgG1
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
TGF beta-1 (TGFB1, Transforming Growth Factor Beta 1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its pro-domain. Activation of TGF beta-1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF beta-1, an amino-terminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP. TGF beta-1 helps regulates proliferation, differentiation, adhesion, migration in many cell types. Many cells have TGF beta receptors, and the protein positively and negatively regulates many other growth factors. TGF beta-1 is cleaved into a latency-associated peptide and a mature TGF beta-1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGF beta-1 homodimer. The mature peptide may also form heterodimers with other TGF beta family members. The gene for TGF beta-1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease and cystic fibrosis.
免疫原 :
TGF乙1来自人类血小板
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Frozen): 1:1,000, Immunohistochemistry (Paraffin): Assay-dependent, Neutralization: Assay-dependent, Western Blot: 5-20 ng/mL
别名 :
CED; cytokine; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGF b; TGF b 1; TGF beta; tgf beta 1; tgf beta1; TGF beta-1; TGF beta-1 protein; TGF ß; TGF ß 1; TGF ß1; Tgfb; TGFB1; TGF-B1; Tgfb-1; TGFbeta; TGF-beta 1; TGF-beta 1 protein; TGFbeta1; TGF-beta1; TGF-beta-1; TGFß1; Transforming growth factor; transforming growth factor b1; transforming growth factor beta; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor ß1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta I; transforming growth factor-beta-1; transforming growth factor-beta-1 precursor; unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔