产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
酪氨酸羟化酶单克隆抗体(185)
目录 :
MA1-24654
规格 :
50微升
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
185
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 6
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:400
Okoshi Y, Tanuma N, Miyata R, Hayashi M. Melatonin alterations and brain acetylcholine lesions in sleep disorders in Cockayne syndrome. Brain Dev. 2014;36:907-13 pubmed 出版商
  • 免疫组化; 人类; 1:400
Okoshi Y, Hayashi M, Kanda S, Yamamoto T. An autopsy case of microencephaly, bizarre putaminal lesion, and cerebellar atrophy with heart and liver diseases. Brain Dev. 2014;36:707-10 pubmed 出版商
  • 免疫组化; 人类; 1:400
Hayashi M, Nakajima K, Miyata R, Tanuma N, Kodama T. Lesions of acetylcholine neurons in refractory epilepsy. ISRN Neurol. 2012;2012:404263 pubmed 出版商
  • 免疫组化; 大鼠
Lundgren O, Jodal M, Jansson M, Ryberg A, Svensson L. Intestinal epithelial stem/progenitor cells are controlled by mucosal afferent nerves. PLoS ONE. 2011;6:e16295 pubmed 出版商
  • 免疫组化; 人类; 1:400
Hayashi M, Hachiya Y, Arai N. An autopsy case presenting repetitive hypoglycemia and unique cortical dysplasia. Brain Dev. 2010;32:289-92 pubmed 出版商
KEARNEY M, Warren T, Hisey E, Qi J, Mooney R. Discrete Evaluative and Premotor Circuits Enable Vocal Learning in Songbirds. Neuron. 2019;104:559-575.e6 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
酪氨酸羟化酶单克隆抗体(185)
目录# :
MA1-24654
规格 :
50微升
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:50, Immunohistochemistry (Frozen): 1:20-1:40, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:25-1:50
物种 :
人类, 小鼠, 大鼠
克隆 :
185
抗体亚型 :
IgG2a
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine. In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4). BH4 binds to the TH catalytic domain, resulting in enzymatic activity. Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated. These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains. TH is also responsible for the conversion of L-tyrosine to L-dopa. TH plays a key role in the physiology of adrenergic neurons. The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.
免疫原 :
Recombinant protein corresponding to the C-terminal portion of mouse Tyrosine Hydroxylase.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:50, Immunohistochemistry (Frozen): 1:20-1:40, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:25-1:50
别名 :
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国