产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
补体C5a单克隆抗体(2952)
目录 :
MA1-40162
规格 :
100微克
价格 :
美国546.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2952
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 2
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| |
产品信息
产品类型 :
抗体
产品名称 :
补体C5a单克隆抗体(2952)
目录# :
MA1-40162
规格 :
100微克
价格 :
美国546.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: 1:50, Functional Assay: 1:50, Immunohistochemistry (Frozen): 1:50, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:50
物种 :
人类
克隆 :
2952
抗体亚型 :
IgG1
储存 :
4° C
描述 :
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.
免疫原 :
Neo-epitope on C5a.
格式 :
液体
应用w/稀释 :
ELISA: 1:50, Functional Assay: 1:50, Immunohistochemistry (Frozen): 1:50, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:50
别名 :
anaphylatoxin; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C4B1; C4B12; C4B2; C4B3; C4B5; C4F; C5; C5a; C5a anaphylatoxin; C5b; C5D; CH; CO4; complement C5; Complement C5 alpha chain; Complement C5 alpha' chain; Complement C5 beta chain; complement component 5; CPAMD3; CPAMD4; DADB-112B14.11; ECLZB; FLJ17816; FLJ17822; FLJ60561; Hc; He; Hemolytic complement; MGC142298; MGC164979; prepro-C5; RGD1561905
更多信息或购买 :
公司信息
赛默飞世尔