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抗体

MARCO单克隆抗体(PLK-1)

MA1-40315

100µg

美国608

单克隆

小鼠

未共轭

PLK-1

人类, 牛

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片

MARCO单克隆抗体(PLK-1)

MA1-40315

100µg

美国608

单克隆

蛋白质G

小鼠

牛, 人类

Flow Cytometry: 1:50, Functional assay: 1:50, Immunofluorescence: 1:50, Immunohistochemistry (Frozen): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:50

牛, 人类

PLK-1

IgG3

4° C

MARCO, also known as SR-A6 or SCARA2, is a macrophage surface receptor and a member of the class A scavenger receptor family. As a part of the innate antimicrobial immune system, MARCO can bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. Due to its expression in tumor infiltrating macrophages, and its role in inhibiting immune responses within tumor environment, MARCO has been indicated as a potential target for cancer immunotherapy.

人类肺泡巨噬细胞

液体

Flow Cytometry: 1:50, Functional assay: 1:50, Immunofluorescence: 1:50, Immunohistochemistry (Frozen): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:50

AI323439; Ly112; Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Marco; SCARA2; Scavenger receptor class A member 2; scavenger receptor class A, member 2; SR-A6