产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
孕酮受体单克隆抗体(甲PR6)
目录 :
MA1-411
规格 :
100微克
价格 :
美国441.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
甲PR6
反应物种 :
豚鼠, llama, 人类, 小鼠, 大鼠, 鸡, 牛, 家羊, domestic rabbit, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 45
| 出版应用/物种/样本/稀释 | 参考文献 |
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| Ruiz Gonzalez I, Sanchez M, Garcia Palencia P, Sanchez B, Garcia Fernandez R, Gonzalez Bulnes A, et al. Differences in uterine immunoexpression of PR, ER? and OTR when comparing prostaglandin- to progestagen-based protocols for ovine estrus synchronization. Anim Reprod Sci. 2012;133:93-100 pubmed 出版商
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| Zang H, Sahlin L, Masironi B, Hirschberg A. Effects of testosterone and estrogen treatment on the distribution of sex hormone receptors in the endometrium of postmenopausal women. Menopause. 2008;15:233-9 pubmed
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| Söderberg M, Johansson B, Masironi B, Bystrom B, Falconer C, Sahlin L, et al. Pelvic floor sex steroid hormone receptors, distribution and expression in pre- and postmenopausal stress urinary incontinent women. Acta Obstet Gynecol Scand. 2007;86:1377-84 pubmed
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| Johannesson U, Sahlin L, Masironi B, Rylander E, Bohm Starke N. Steroid receptor expression in the vulvar vestibular mucosa--effects of oral contraceptives and menstrual cycle. Contraception. 2007;76:319-25 pubmed
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| McCarthy A, Savage K, Gabriel A, Naceur C, Reis Filho J, Ashworth A. A mouse model of basal-like breast carcinoma with metaplastic elements. J Pathol. 2007;211:389-98 pubmed
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| Giles J, Olson L, Johnson P. Characterization of ovarian surface epithelial cells from the hen: a unique model for ovarian cancer. Exp Biol Med (Maywood). 2006;231:1718-25 pubmed
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| Sahlin L, Masironi B, Akerberg S, Eriksson H. Tissue- and hormone-dependent progesterone receptor distribution in the rat uterus. Reprod Biol Endocrinol. 2006;4:47 pubmed
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| Satterfield M, Bazer F, Spencer T. Progesterone regulation of preimplantation conceptus growth and galectin 15 (LGALS15) in the ovine uterus. Biol Reprod. 2006;75:289-96 pubmed
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| Juengel J, Heath D, Quirke L, McNatty K. Oestrogen receptor alpha and beta, androgen receptor and progesterone receptor mRNA and protein localisation within the developing ovary and in small growing follicles of sheep. Reproduction. 2006;131:81-92 pubmed
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Mote P, Arnett Mansfield R, Gava N, deFazio A, Mulac Jericevic B, Conneely O, et al. Overlapping and distinct expression of progesterone receptors A and B in mouse uterus and mammary gland during the estrous cycle. Endocrinology. 2006;147:5503-12 pubmed
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Yang Z, Wolf I, Chen H, Periyasamy S, Chen Z, Yong W, et al. FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor A isoform. Mol Endocrinol. 2006;20:2682-94 pubmed
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Botos J, Xian W, Smith D, Smith C. Progesterone receptor deficient in chromatin binding has an altered cellular state. J Biol Chem. 2004;279:15231-9 pubmed
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Stavreus Evers A, Hovatta O, Eriksson H, Landgren B. Development and characterization of an endometrial tissue culture system. Reprod Biomed Online. 2003;7:243-9 pubmed
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Isaksson E, Wang H, Sahlin L, von Schoultz B, Cline J, von Schoultz E. Effects of long-term HRT and tamoxifen on the expression of progesterone receptors A and B in breast tissue from surgically postmenopausal cynomolgus macaques. Breast Cancer Res Treat. 2003;79:233-9 pubmed
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Farnell Y, Ing N. Myometrial effects of selective estrogen receptor modulators on estradiol-responsive gene expression are gene and cell-specific. J Steroid Biochem Mol Biol. 2003;84:527-36 pubmed
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Farnell Y, Ing N. Endometrial effects of selective estrogen receptor modulators (SERMs) on estradiol-responsive gene expression are gene and cell-specific. J Steroid Biochem Mol Biol. 2003;84:513-26 pubmed
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Wang H, Isaksson E, von Schoultz B, Cline J, Sahlin L. Effect of long-term treatment with steroid hormones or tamoxifen on the progesterone receptor and androgen receptor in the endometrium of ovariectomized cynomolgus macaques. Reprod Biol Endocrinol. 2003;1:7 pubmed
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Gray C, Stewart M, Johnson G, Spencer T. Postpartum uterine involution in sheep: histoarchitecture and changes in endometrial gene expression. Reproduction. 2003;125:185-98 pubmed
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Wu X, Wang H, Englund K, Blanck A, Lindblom B, Sahlin L. Expression of progesterone receptors A and B and insulin-like growth factor-I in human myometrium and fibroids after treatment with a gonadotropin-releasing hormone analogue. Fertil Steril. 2002;78:985-93 pubmed
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Stavreus Evers A, Nikas G, Sahlin L, Eriksson H, Landgren B. Formation of pinopodes in human endometrium is associated with the concentrations of progesterone and progesterone receptors. Fertil Steril. 2001;76:782-91 pubmed
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Taylor K, Gray C, Joyce M, Stewart M, Bazer F, Spencer T. Neonatal ovine uterine development involves alterations in expression of receptors for estrogen, progesterone, and prolactin. Biol Reprod. 2000;63:1192-204 pubmed
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Johnson G, Spencer T, Burghardt R, Taylor K, Gray C, Bazer F. Progesterone modulation of osteopontin gene expression in the ovine uterus. Biol Reprod. 2000;62:1315-21 pubmed
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Johnson G, Spencer T, Burghardt R, Joyce M, Bazer F. Interferon-tau and progesterone regulate ubiquitin cross-reactive protein expression in the ovine uterus. Biol Reprod. 2000;62:622-7 pubmed
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Allison Gray C, Bartol F, Taylor K, Wiley A, Ramsey W, Ott T, et al. Ovine uterine gland knock-out model: effects of gland ablation on the estrous cycle. Biol Reprod. 2000;62:448-56 pubmed
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Spencer T, Gray A, Johnson G, Taylor K, Gertler A, Gootwine E, et al. Effects of recombinant ovine interferon tau, placental lactogen, and growth hormone on the ovine uterus. Biol Reprod. 1999;61:1409-18 pubmed
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Ing N, Tornesi M. Estradiol up-regulates estrogen receptor and progesterone receptor gene expression in specific ovine uterine cells. Biol Reprod. 1997;56:1205-15 pubmed
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Estes P, Suba E, Lawler Heavner J, Elashry Stowers D, Wei L, Toft D, et al. Immunologic analysis of human breast cancer progesterone receptors. 1. Immunoaffinity purification of transformed receptors and production of monoclonal antibodies. Biochemistry. 1987;26:6250-62 pubmed
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Schneider W, Toft D, Sullivan W, Shyamala G. Interaction of murine progesterone receptors with specific monoclonal antibodies to the avian progesterone receptor. J Steroid Biochem. 1988;29:297-306 pubmed
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Bergeron C, Ferenczy A, Toft D, Schneider W, Shyamala G. Immunocytochemical study of progesterone receptors in the human endometrium during the menstrual cycle. Lab Invest. 1988;59:862-9 pubmed
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Bergeron C, Ferenczy A, Toft D, Shyamala G. Immunocytochemical study of progesterone receptors in hyperplastic and neoplastic endometrial tissues. Cancer Res. 1988;48:6132-6 pubmed
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Pekki A, Joensuu T, Vidqvist K, Toft D, Tuohimaa P. Progesterone receptor concentration differences in the chick oviduct cells and apparent down-regulation by ligand. A semiquantitative immunohistochemical study. J Steroid Biochem. 1989;34:351-4 pubmed
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Joensuu T, Ylikomi T, Toft D, Keinanen R, Kulomaa M, Tuohimaa P. Progesterone-induced avidin as a marker of cytodifferentiation in the oviduct: comparison to ovalbumin. Endocrinology. 1990;126:1143-55 pubmed
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Yoshimura Y, Bahr J. Localization of progesterone receptors in pre- and postovulatory follicles of the domestic hen. Endocrinology. 1991;128:323-30 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
孕酮受体单克隆抗体(甲PR6)
目录# :
MA1-411
规格 :
100微克
价格 :
美国441.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Bovine, Chicken, Guinea Pig, Human, Mouse, Ovine, Rabbit, Rat
应用 :
Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 20 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1 µg/mL
物种 :
Bovine, Chicken, Guinea Pig, Human, Mouse, Ovine, Rabbit, Rat
克隆 :
甲PR6
抗体亚型 :
IgG2a
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
The progesterone receptor (PR) is a member of the steroid family of nuclear receptors. The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites. PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation. PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus. This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity. In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins. Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription. A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.
免疫原 :
Progesterone receptor purified from chick oviduct cytosol.
格式 :
冻干
应用w/稀释 :
Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 20 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1 µg/mL
别名 :
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔