产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Phospho-RNA pol II CTD (Ser5) Monoclonal Antibody (4H8)
目录 :
MA1-46093
规格 :
100微克
价格 :
美国450.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4H8
反应物种 :
酿酒酵母S288C, 人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 核糖核酸免疫沉淀
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 7
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 人类
Yang Z, Broz D, Noderer W, Ferreira J, Overton K, Spencer S, et al. p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stress. Cell Death Differ. 2015;22:560-73 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 1:500
Li Q, Pène V, Krishnamurthy S, Cha H, Liang T. Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly. Nat Med. 2013;19:722-9 pubmed 出版商
  • 免疫印迹; 人类
Zhu Q, Wani G, Sharma N, Wani A. Lack of CAK complex accumulation at DNA damage sites in XP-B and XP-B/CS fibroblasts reveals differential regulation of CAK anchoring to core TFIIH by XPB and XPD helicases during nucleotide excision repair. DNA Repair (Amst). 2012;11:942-50 pubmed 出版商
Shim H, Horner J, Wu C, Li J, Lan Z, Jiang S, et al. Telomerase Reverse Transcriptase Preserves Neuron Survival and Cognition in Alzheimer's Disease Models. Nat Aging. 2021;1:1162-1174 pubmed 出版商
Mert U, Adawy A, Scharff E, Teichmann P, Willms A, Haselmann V, et al. TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors. Cancers (Basel). 2019;11: pubmed 出版商
Zhang P, Chen Z, Li R, Guo Y, Shi H, Bai J, et al. Loss of ASXL1 in the bone marrow niche dysregulates hematopoietic stem and progenitor cell fates. Cell Discov. 2018;4:4 pubmed 出版商
Di Blasi C, Bellafiore E, Salih M, Manzini M, Moore S, Seidahmed M, et al. Variable disease severity in Saudi Arabian and Sudanese families with c.3924 + 2 T > C mutation of LAMA2. BMC Res Notes. 2011;4:534 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
Phospho-RNA pol II CTD (Ser5) Monoclonal Antibody (4H8)
目录# :
MA1-46093
规格 :
100微克
价格 :
美国450.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠, 酵母
应用 :
ChIP Assay: 1-10 µL, CUT&RUN: Assay-dependent, ELISA: 1:100-1:2,000, Immunocytochemistry: 1:50 - 1:100, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 1-5 µg, RNA Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000-1:20,000
物种 :
人类, 小鼠, 酵母
克隆 :
4H8
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
RNA polymerase II is the enzyme responsible for the synthesis of mRNA and many non-coding RNAs. POLR2A encodes RNA polymerase II subunit B1 (RPB1), the largest subunit of RNA polymerase II. The C-terminal domain (CTD) of RPB1 contains tandem heptapeptide repeats with the consensus sequence YSPTSPS. Phosphorylation and other modifications within this sequence influence the recruitment of factors that regulate the transcription cycle. Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the CTD.
免疫原 :
Chemically synthesized phospho-ser 5 YSPTSpPS (Human).
格式 :
液体
应用w/稀释 :
ChIP Assay: 1-10 µL, CUT&RUN: Assay-dependent, ELISA: 1:100-1:2,000, Immunocytochemistry: 1:50 - 1:100, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 1-5 µg, RNA Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000-1:20,000
别名 :
220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; Pola1; POLR2; POLR2A; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; polymerase, alpha 1; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II carboxy-terminal domain; RNA polymerase II C-terminal domain; RNA polymerase II largest subunit; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国