产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CENPE单克隆抗体(1H12)
目录 :
MA1-5758
规格 :
100微升
价格 :
美国766.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1H12
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 1
产品信息
产品类型 :
抗体
产品名称 :
CENPE单克隆抗体(1H12)
目录# :
MA1-5758
规格 :
100微升
价格 :
美国766.00
克隆性 :
单克隆
纯度 :
离子交换层析
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 1.0 µg/1x10^6 cells, Immunocytochemistry: Assay-dependent, Immunoprecipitation: 3 µg/300 mg lysate, Western Blot: 0.5-1 µg/mL
物种 :
人类
克隆 :
1H12
抗体亚型 :
IgG, kappa
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
14-3-3 sigma (stratifin, SFN, epithelial cell marker protein 1) is a member of a highly conserved family of 14-3-3 proteins that are present in all eukaryotic organisms. There are 7 known mammalian 14-3-3 isoforms epsilon, beta, zeta, gamma, theta, tau and they play important roles in many biological activities by binding to and altering the subcellular localization and/or stability of key molecules in various signaling cascades. 14-3-3 sigma was originally characterized as a human mammary epithelium marker and later rediscovered as an important molecule for cell cycle checkpoint regulation. Recently it has been reported that 14-3-3 sigma may serve as a prognosis marker predicting survival of pancreatic cancer patient treatment. 14-3-3 sigmais the only 14-3-3 isoform induced by the tumor suppressor protein p53, in response to g -irradiation and other DNA-damaging agents. 14-3-3 sigmais a p53-regulated inhibitor of G2/M progression and acts as a tumor suppressor gene that is inactivated by methylation of its 5' CpG islands in epithelial tumor cells. Two isoforms of human 14-3-3 sigma are produced by alternative splicing.
免疫原 :
重组全长CENP-E蛋白(人类)来自SP2/0细胞
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1.0 µg/1x10^6 cells, Immunocytochemistry: Assay-dependent, Immunoprecipitation: 3 µg/300 mg lysate, Western Blot: 0.5-1 µg/mL
别名 :
312kDa; AU019344; BC049989; C530022J18; Cenpe; CENP-E; centromere autoantigen E; Centromere autoantigen E (312kD); centromere protein E; centromere protein E, 312kDa; centromere-associated protein E; centromeric protein E; KIF10; kinesin 10; kinesin family member 10; kinesin superfamily protein 10; Kinesin-7; Kinesin-related protein CENPE; MCPH13; Motor domain of KIF10; N-7 kinesin; PPP1R61; protein phosphatase 1, regulatory subunit 61
更多信息或购买 :
公司信息
赛默飞世尔