产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
α微管蛋白单克隆抗体(YL1/2)
目录 :
MA1-80017
规格 :
500微克
价格 :
美国496.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
YL1/2
反应物种 :
酿酒酵母S288C, African green monkey, Dictyostelium discoideum, 人类, 小鼠, 大鼠, 犬, pigs , fruit fly , 非洲爪蛙, domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 64
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:1000; 图 2b
Schilpp C, Lochbaum R, Braubach P, Jonigk D, Frick M, Dietl P, et al. TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei. Pflugers Arch. 2021;473:287-311 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2b
Chan K, Son S, Schmid E, Fletcher D. A viral fusogen hijacks the actin cytoskeleton to drive cell-cell fusion. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 6e
Mantri C, St John A. Immune synapses between mast cells and γδ T cells limit viral infection. J Clin Invest. 2019;129:1094-1108 pubmed 出版商
  • 免疫细胞化学; African green monkey; 图 1d
van Riel W, Rai A, Bianchi S, Katrukha E, Liu Q, Heck A, et al. Kinesin-4 KIF21B is a potent microtubule pausing factor. elife. 2017;6: pubmed 出版商
  • 免疫细胞化学; 人类; 1:500
van de Ven R, de Groot J, Park D, van Domselaar R, de Jong D, Szuhai K, et al. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nat Commun. 2016;7:13874 pubmed 出版商
  • 免疫细胞化学; Dictyostelium discoideum; 图 s6g
Artemenko Y, Axiotakis L, Borleis J, Iglesias P, Devreotes P. Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks. Proc Natl Acad Sci U S A. 2016;113:E7500-E7509 pubmed
  • 免疫细胞化学; 人类; 图 7a
Liu Q, Liu F, Yu K, Tas R, Grigoriev I, Remmelzwaal S, et al. MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis. J Biol Chem. 2016;291:20617-29 pubmed 出版商
  • 免疫细胞化学; 犬; 1:500; 图 4a
Bernabé Rubio M, Andrés G, Casares Arias J, Fernández Barrera J, Rangel L, Reglero Real N, et al. Novel role for the midbody in primary ciliogenesis by polarized epithelial cells. J Cell Biol. 2016;214:259-73 pubmed 出版商
  • 免疫细胞化学; African green monkey; 图 2
Chozinski T, Halpern A, Okawa H, Kim H, Tremel G, Wong R, et al. Expansion microscopy with conventional antibodies and fluorescent proteins. Nat Methods. 2016;13:485-8 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1
Pal K, Hwang S, Somatilaka B, Badgandi H, Jackson P, DeFea K, et al. Smoothened determines ?-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. J Cell Biol. 2016;212:861-75 pubmed 出版商
  • 免疫印迹; domestic rabbit; 图 2
Cawthorn W, Scheller E, Parlee S, Pham H, Learman B, Redshaw C, et al. Expansion of Bone Marrow Adipose Tissue During Caloric Restriction Is Associated With Increased Circulating Glucocorticoids and Not With Hypoleptinemia. Endocrinology. 2016;157:508-21 pubmed 出版商
  • 免疫细胞化学; 犬
Reales E, Bernabé Rubio M, Casares Arias J, Rentero C, Fernández Barrera J, Rangel L, et al. The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation. J Cell Sci. 2015;128:2261-70 pubmed 出版商
  • 免疫印迹; 大鼠
Cawthorn W, Bree A, Yao Y, Du B, Hemati N, Martinez Santibañez G, et al. Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a ?-catenin-dependent mechanism. Bone. 2012;50:477-89 pubmed 出版商
  • 免疫细胞化学; African green monkey; 图 5
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  • 免疫细胞化学; Dictyostelium discoideum; 图 1a
Roos U, De Brabander M, De Mey J. Indirect immunofluorescence of microtubules in Dictyostelium discoideum. A study with polyclonal and monoclonal antibodies to tubulins. Exp Cell Res. 1984;151:183-93 pubmed
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Kishi J, Liu N, West E, Sheng K, Jordanides J, Serrata M, et al. Light-Seq: light-directed in situ barcoding of biomolecules in fixed cells and tissues for spatially indexed sequencing. Nat Methods. 2022;19:1393-1402 pubmed 出版商
Lee V, Heffern M. Structure-activity assessment of flavonoids as modulators of copper transport. Front Chem. 2022;10:972198 pubmed 出版商
Zhang Y, Hong X, Hua S, Jiang K. Reconstitution and mechanistic dissection of the human microtubule branching machinery. J Cell Biol. 2022;221: pubmed 出版商
Landskron L, Bak J, Adamopoulos A, Kaplani K, Moraiti M, van den Hengel L, et al. Posttranslational modification of microtubules by the MATCAP detyrosinase. Science. 2022;376:eabn6020 pubmed 出版商
Lerner L, Bonte D, Le Guillou M, Mohammad M, Kasraian Z, Sarasin A, et al. Expression of Constitutive Fusion of Ubiquitin to PCNA Restores the Level of Immunoglobulin A/T Mutations During Somatic Hypermutation in the Ramos Cell Line. Front Immunol. 2022;13:871766 pubmed 出版商
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Kuzmic M, Linares G, Fialová J, Iv F, Salaün D, Llewellyn A, et al. Septin-microtubule association via a motif unique to the isoform 1 of septin 9 tunes stress fibers. J Cell Sci. 2021;: pubmed 出版商
Weissbourd B, Momose T, Nair A, Kennedy A, Hunt B, Anderson D. A genetically tractable jellyfish model for systems and evolutionary neuroscience. Cell. 2021;184:5854-5868.e20 pubmed 出版商
Hurst V, Challa K, Jonas F, Forey R, Sack R, Seebacher J, et al. A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress. EMBO J. 2021;40:e108439 pubmed 出版商
Sinclair A, Huynh C, Sladewski T, Zuromski J, Ruiz A, de Graffenried C. The Trypanosoma brucei subpellicular microtubule array is organized into functionally discrete subdomains defined by microtubule associated proteins. PLoS Pathog. 2021;17:e1009588 pubmed 出版商
Li M, Ferretti M, Ying B, Descamps H, Lee E, Dittmar M, et al. Pharmacological activation of STING blocks SARS-CoV-2 infection. Sci Immunol. 2021;6: pubmed 出版商
Gersing S, Wang Y, Grønbæk Thygesen M, Kampmeyer C, Clausen L, Willemoes M, et al. Mapping the degradation pathway of a disease-linked aspartoacylase variant. PLoS Genet. 2021;17:e1009539 pubmed 出版商
Vukušić K, Ponjavić I, Buđa R, Risteski P, Tolić I. Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation. Dev Cell. 2021;56:1253-1267.e10 pubmed 出版商
Chan K, Arthur A, Morstein J, Jin M, Bhat A, Schlesinger D, et al. Evolutionarily related small viral fusogens hijack distinct but modular actin nucleation pathways to drive cell-cell fusion. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
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Hosawi S, Humphries J, Coward R, Knight D, Humphries M, Lennon R. Global proteomic analysis of insulin receptor interactors in glomerular podocytes. Wellcome Open Res. 2020;5:202 pubmed 出版商
Evans L, Anglen T, Scott P, Lukasik K, Loncarek J, Holland A. ANKRD26 recruits PIDD1 to centriolar distal appendages to activate the PIDDosome following centrosome amplification. EMBO J. 2020;:e105106 pubmed 出版商
Lagardère M, Chamma I, Bouilhol E, Nikolski M, Thoumine O. FluoSim: simulator of single molecule dynamics for fluorescence live-cell and super-resolution imaging of membrane proteins. Sci Rep. 2020;10:19954 pubmed 出版商
Lee E, Wolf E, Ihn S, Smith H, Emili A, Palazzo A. TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes. Nucleic Acids Res. 2020;48:11645-11663 pubmed 出版商
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Ullah I, Gahalawat S, Booshehri L, Niederstrasser H, Majumdar S, Leija C, et al. An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization. ACS Infect Dis. 2020;6:2057-2072 pubmed 出版商
Suchacki K, Tavares A, Mattiucci D, Scheller E, Papanastasiou G, Gray C, et al. Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis. Nat Commun. 2020;11:3097 pubmed 出版商
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Lei X, Ning Y, Eid Elesawi I, Yang K, Chen C, Wang C, et al. Heat stress interferes with chromosome segregation and cytokinesis during male meiosis in Arabidopsis thaliana. Plant Signal Behav. 2020;15:1746985 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
α微管蛋白单克隆抗体(YL1/2)
目录# :
MA1-80017
规格 :
500微克
价格 :
美国496.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
狗, 果蝇, 人类, 小鼠, 植物, 猪, 兔, 大鼠, 非洲爪蛙, 酵母
应用 :
ELISA: 1:100-1:1,000, Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent, Radioimmune assays: Assay-dependent, Western Blot: 2 µg/mL
物种 :
狗, 果蝇, 人类, 小鼠, 植物, 猪, 兔, 大鼠, 非洲爪蛙, 酵母
克隆 :
YL1/2
抗体亚型 :
IgG2a
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
免疫原 :
酵母微管蛋白
格式 :
液体
应用w/稀释 :
ELISA: 1:100-1:1,000, Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent, Radioimmune assays: Assay-dependent, Western Blot: 2 µg/mL
别名 :
&agr-tubulin 84B; 1t; a1t; ALPHA 84C; alpha tubulin; alpha tubulin 84B; alpha[[1]] tubulin; alpha[[1]]-tubulin; alpha1; alpha1 tubulin; alpha1t; alpha1tub; alpha1tub84B; alpha1-tubulin; alpha84B; alphaT; alphat-1; alphatub; alpha-tub; alphaTub1; alphatub84; alphaTUB84B; alpha-tub84B; alphaTub84B-PA; alphatubulin; alpha-tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3D; Alpha-tubulin 3E; alpha-tubulin 4; Alpha-tubulin 6; alphaTubulin 84B; alpha-Tubulin 84B; alpha-Tubulin at 84B; alpha-tubulin I; Alpha-tubulin II; alpha-tubulin III; Alpha-tubulin isotype M-alpha-1; alpha-tubulin isotype M-alpha-2; Alpha-tubulin isotype M-alpha-4; alpha-tubulin isotype M-alpha-6; alpha-tubulin TUB1; alpha-tubulin ubiquitous; alphaTubulin84B; Alpha-Tubulin84B; ALS22; anon-EST:Liang-1.59; anon-EST:Liang-2.30; AT25469p; aTub84B; a-tub84B; bA408E5.3; B-ALPHA-1; bcm948; BEST:LD32507; cb944; CG1913; CG1913-PA; chr3R:2914276. 2914416; clone 1.59; clone 2.30; Detyrosinated tubulin alpha-1A chain; Detyrosinated tubulin alpha-1B chain; Detyrosinated tubulin alpha-1C chain; Detyrosinated tubulin alpha-3 chain; Detyrosinated tubulin alpha-3C chain; Detyrosinated tubulin alpha-3D chain; Detyrosinated tubulin alpha-3E chain; DM1alpha; Dmel CG1913; Dmel_CG1913; DTA1; fb22g06; FLJ30169; H2 ALPHA; H2-ALPHA; hum-a-tub1; hum-a-tub2; I79_019110; K-ALPHA-1; l(3)84Bd; l(3)g3; lis3; LOC100726777; LOC100731885; LOC100857858; LOC101118307; LOC106557476; M[a]4; M[a]6; ms(3)nc33; nc33; RGD1565476; similar to alpha-tubulin isoform 1; similar to tubulin alpha 1; T; Talpha1; Talpha1 alpha-tubulin; TBA1_DROME; Testis-specific alpha-tubulin; Tub; Tub 84B; TUB1; Tub1C; Tub84B; TUBA1; Tuba-1; tuba1 protein; TUBA1/3/4; Tuba1a; tuba1a.L; tuba1a-a; tuba1a-b; TUBA1B; TUBA1C; tuba1l; tuba1l2; TUBA2; TUBA3; TUBA3C; TUBA3D; TUBA3E; Tuba4; Tuba4a; TUBA5; Tuba6; tuba8.S; tubA84B; tubal2; Tubalpha1; tubulin; tubulin 1 alpha-chain; tubulin 1alpha; tubulin alpha; tubulin alpha 1a; tubulin alpha 1a L homeolog; tubulin alpha 1b; tubulin alpha 1c; tubulin alpha 3; tubulin alpha 3c; tubulin alpha 3e; tubulin alpha 4a; tubulin alpha 6; tubulin alpha 8 S homeolog; tubulin alpha1; tubulin alpha-1 chain; tubulin alpha1 promoter; Tubulin alpha-1A chain; tubulin alpha-1B chain; Tubulin alpha-1C chain; tubulin alpha-1C chain-like; tubulin alpha-2 chain; Tubulin alpha-3 chain; Tubulin alpha-3C chain; tubulin alpha-3C/D chain; Tubulin alpha-3D chain; Tubulin alpha-3E chain; tubulin alpha-4 chain; Tubulin alpha-4A chain; Tubulin alpha-5 chain; tubulin alpha-5 chain-like; tubulin alpha-6 chain; tubulin alpha-8 chain; tubulin alpha-ubiquitous chain; tubulin B-alpha-1; Tubulin H2-alpha; tubulin K-alpha-1; tubulin(alpha1); tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1, like; tubulin, alpha 1, like 2; tubulin, alpha 1a; tubulin, alpha 1b; tubulin, alpha 1c; tubulin, alpha 2; tubulin, alpha 3c; tubulin, alpha 3e; tubulin, alpha 4; tubulin, alpha 4a; tubulin, alpha 5; tubulin, alpha 6; tubulin, alpha, brain-specific; tubulin, alpha, ubiquitous; tubulin1alpha; tubulin84B; Tubulin-alpha1; Unknown (protein for MGC:133894); unnamed protein product; wu:fb22g06; wu:fb37a10; XELAEV_18019849mg; XELAEV_18020901mg; YML085C
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国