产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD11b/c单克隆抗体(OX-42)
目录 :
MA1-80774
规格 :
1毫克
价格 :
美国930.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
OX-42
反应物种 :
小鼠, 大鼠
应用 :
免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 大鼠; 图 6e
Tuncel J, Haag S, Holmdahl R. MHC class II alleles associated with Th1 rather than Th17 type immunity drive the onset of early arthritis in a rat model of rheumatoid arthritis. Eur J Immunol. 2017;47:563-574 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1
Lee J, Kang S, Yune T. Fluoxetine prevents oligodendrocyte cell death by inhibiting microglia activation after spinal cord injury. J Neurotrauma. 2015;32:633-44 pubmed 出版商
  • 流式细胞仪; 大鼠
Castelo Branco M, Soares I, Lopes D, Buongusto F, Martinusso C, do Rosario A, et al. Intraperitoneal but not intravenous cryopreserved mesenchymal stromal cells home to the inflamed colon and ameliorate experimental colitis. PLoS ONE. 2012;7:e33360 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200
Ki K, Park D, Lee S, Kim N, Choi B, Noh G. The optimal concentration of siRNA for gene silencing in primary cultured astrocytes and microglial cells of rats. Korean J Anesthesiol. 2010;59:403-10 pubmed 出版商
  • 免疫组化-自由浮动切片; 大鼠; 1:50; 图 5
Zhang L, Wei W, Li Y, Wang Y. A rat model of mild cognitive impairment associated with vascular factor. Neuropathology. 2011;31:112-21 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Samantaray S, Knaryan V, Guyton M, Matzelle D, Ray S, Banik N. The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats. Neuroscience. 2007;146:741-55 pubmed
  • 免疫组化-冰冻切片; 大鼠; 1:100; 图 2
Svensson C, Fitzsimmons B, Azizi S, Powell H, Hua X, Yaksh T. Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization. J Neurochem. 2005;92:1508-20 pubmed
  • 免疫组化-冰冻切片; 大鼠; 1:100; 图 5
Svensson C, Marsala M, Westerlund A, Calcutt N, Campana W, Freshwater J, et al. Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing. J Neurochem. 2003;86:1534-44 pubmed
  • 免疫组化; 大鼠; 1:100
Svensson C, Hua X, Protter A, Powell H, Yaksh T. Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesia. Neuroreport. 2003;14:1153-7 pubmed
  • 流式细胞仪; 大鼠
Vari F, Lord R, Goto S. LSF-1 may modulate the indirect allorecognition pathway to delay allograft rejection. Transpl Immunol. 2002;10:259-67 pubmed
  • 流式细胞仪; 大鼠
Inada T, Taniuchi S, Shingu K, Kobayashi Y, Fujisawa J, Nakao S. Propofol depressed neutrophil hydrogen peroxide production more than midazolam, whereas adhesion molecule expression was minimally affected by both anesthetics in rats with abdominal sepsis. Anesth Analg. 2001;92:437-41 pubmed
  • 免疫细胞化学; 大鼠; 1:100; 图 2
Ray S, Schaecher K, Shields D, Hogan E, Banik N. Combined TUNEL and double immunofluorescent labeling for detection of apoptotic mononuclear phagocytes in autoimmune demyelinating disease. Brain Res Brain Res Protoc. 2000;5:305-11 pubmed
  • 免疫组化; 大鼠; 图 3
Sigurdsson E, Permanne B, Soto C, Wisniewski T, Frangione B. In vivo reversal of amyloid-beta lesions in rat brain. J Neuropathol Exp Neurol. 2000;59:11-7 pubmed
  • 流式细胞仪; 大鼠
Lan F, Hayamizu K, Strober S. Cyclosporine facilitates chimeric and inhibits nonchimeric tolerance after posttransplant total lymphoid irradiation. Transplantation. 2000;69:649-55 pubmed
  • 流式细胞仪; 大鼠; 图 1
Hayamizu K, Lan F, Huie P, Sibley R, Strober S. Comparison of chimeric acid and non-chimeric tolerance using posttransplant total lymphoid irradiation: cytokine expression and chronic rejection. Transplantation. 1999;68:1036-44 pubmed
  • 流式细胞仪; 大鼠
Hayamizu K, Huie P, Sibley R, Strober S. Monocyte-derived dendritic cell precursors facilitate tolerance to heart allografts after total lymphoid irradiation. Transplantation. 1998;66:1285-91 pubmed
  • 流式细胞仪; 大鼠
Hayamizu K, Zeng D, Huie P, Garcia Ojeda M, Bloch D, Fong L, et al. Donor blood monocytes but not T or B cells facilitate long-term allograft survival after total lymphoid irradiation. Transplantation. 1998;66:585-93 pubmed
  • 免疫组化-冰冻切片; 大鼠
Fathallah Shaykh H, Gao W, Cho M, Herrera M. Priming in the brain, an immunologically privileged organ, elicits anti-tumor immunity. Int J Cancer. 1998;75:266-76 pubmed
  • 流式细胞仪; 大鼠
  • 免疫沉淀; 大鼠
Tamatani T, Kotani M, Miyasaka M. Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. Eur J Immunol. 1991;21:627-33 pubmed
Kitase Y, Chin E, Ramachandra S, Burkhardt C, Madurai N, Lenz C, et al. Sustained peripheral immune hyper-reactivity (SPIHR): an enduring biomarker of altered inflammatory responses in adult rats after perinatal brain injury. J Neuroinflammation. 2021;18:242 pubmed 出版商
Stevens A, Liu L, Bertovich D, Janjic J, Pollock J. Differential Expression of Neuroinflammatory mRNAs in the Rat Sciatic Nerve Following Chronic Constriction Injury and Pain-Relieving Nanoemulsion NSAID Delivery to Infiltrating Macrophages. Int J Mol Sci. 2019;20: pubmed 出版商
Bucan V, Fliess M, Schnabel R, Peck C, Vaslaitis D, Fülbier A, et al. In vitro enhancement and functional characterization of neurite outgrowth by undifferentiated adipose-derived stem cells. Int J Mol Med. 2019;43:593-602 pubmed 出版商
Wu Y, Shen L, Wang R, Tang J, Ding S, Wang S, et al. Increased ceruloplasmin expression caused by infiltrated leukocytes, activated microglia, and astrocytes in injured female rat spinal cords. J Neurosci Res. 2018;96:1265-1276 pubmed 出版商
Deosarkar S, PRABHAKARPANDIAN B, Wang B, Sheffield J, Krynska B, Kiani M. A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip. PLoS ONE. 2015;10:e0142725 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD11b/c单克隆抗体(OX-42)
目录# :
MA1-80774
规格 :
1毫克
价格 :
美国930.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
大鼠
应用 :
Flow Cytometry: 1:50-1:100, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:50-1:100, Immunoprecipitation: Assay-dependent
物种 :
大鼠
克隆 :
OX-42
抗体亚型 :
IgG2a
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. CD11b is also a receptor for fibrogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8% spleen cells, 44% bone marrow cells and less than 1% thymocytes and is commonly used as a microgial marker in nervous tissue. CD11c encodes the integrin alpha X chain protein. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Mutations affecting the CD11b/c gene lead to systemic lupus erythematosus 6.
免疫原 :
大鼠腹腔巨噬细胞
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:50-1:100, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:50-1:100, Immunoprecipitation: Assay-dependent
别名 :
AI449405; antigen CD11b (p170); CD11 antigen-like family member B; CD11 antigen-like family member C; CD11b; CD11B (p170); CD11b/CD18; CD11bc; CD11C; CD11C (p150) alpha polypeptide; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component 3 receptor 4 subunit; complement component receptor 3 alpha-a; complement receptor 4; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; Cr4; F730045J24Rik; integrin alpha M; integrin alpha X; integrin alpha-M; Integrin alpha-X; integrin aX; integrin subunit alpha M; integrin subunit alpha X; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); ITGAM; ITGAX; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor MO1; leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; Ly-40; MAC1; MAC-1; Mac-1 alpha; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; myeloid membrane antigen, alpha subunit; N418; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; OX42; OX-42; p150 95 integrin alpha chain; RGD1561123; SLEB6
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国