产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
SRC1单克隆抗体(1135/H4)
目录 :
MA1-840
规格 :
100微升
价格 :
美国420.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1135/H4
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 小鼠; 图 3c
Kumar S, Cunningham T, Duester G. Nuclear receptor corepressors Ncor1 and Ncor2 (Smrt) are required for retinoic acid-dependent repression of Fgf8 during somitogenesis. Dev Biol. 2016;418:204-215 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Meneses Morales I, Tecalco Cruz A, Barrios Garcia T, Gómez Romero V, Trujillo Gonzalez I, Reyes Carmona S, et al. SIP1/NHERF2 enhances estrogen receptor alpha transactivation in breast cancer cells. Nucleic Acids Res. 2014;42:6885-900 pubmed 出版商
  • 免疫沉淀; 人类
Merenbakh Lamin K, Ben Baruch N, Yeheskel A, Dvir A, Soussan Gutman L, Jeselsohn R, et al. D538G mutation in estrogen receptor-?: A novel mechanism for acquired endocrine resistance in breast cancer. Cancer Res. 2013;73:6856-64 pubmed 出版商
  • 免疫组化; 人类
Kumagami A, Ito A, Yoshida Komiya H, Fujimori K, Sato A. Expression patterns of the steroid receptor coactivator family in human ovarian endometriosis. J Obstet Gynaecol Res. 2011;37:1269-76 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Zhang Z, Kovalenko P, Cui M, Desmet M, Clinton S, Fleet J. Constitutive activation of the mitogen-activated protein kinase pathway impairs vitamin D signaling in human prostate epithelial cells. J Cell Physiol. 2010;224:433-42 pubmed 出版商
Li G, Heaton J, Gelehrter T. Role of steroid receptor coactivators in glucocorticoid and transforming growth factor beta regulation of plasminogen activator inhibitor gene expression. Mol Endocrinol. 2006;20:1025-34 pubmed
Agoulnik I, Vaid A, Bingman W, Erdeme H, Frolov A, Smith C, et al. Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression. Cancer Res. 2005;65:7959-67 pubmed
Ruas J, Poellinger L, Pereira T. Role of CBP in regulating HIF-1-mediated activation of transcription. J Cell Sci. 2005;118:301-11 pubmed
Zhang C, Dowd D, Staal A, Gu C, Lian J, Van Wijnen A, et al. Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing. J Biol Chem. 2003;278:35325-36 pubmed
Li Q, Su A, Chen J, Lefebvre Y, Haché R. Attenuation of glucocorticoid signaling through targeted degradation of p300 via the 26S proteasome pathway. Mol Endocrinol. 2002;16:2819-27 pubmed
Gregory C, Wilson E, Apparao K, Lininger R, Meyer W, Kowalik A, et al. Steroid receptor coactivator expression throughout the menstrual cycle in normal and abnormal endometrium. J Clin Endocrinol Metab. 2002;87:2960-6 pubmed
Sharma D, Fondell J. Ordered recruitment of histone acetyltransferases and the TRAP/Mediator complex to thyroid hormone-responsive promoters in vivo. Proc Natl Acad Sci U S A. 2002;99:7934-9 pubmed
Yi M, Tong G, Murry B, Mendelson C. Role of CBP/p300 and SRC-1 in transcriptional regulation of the pulmonary surfactant protein-A (SP-A) gene by thyroid transcription factor-1 (TTF-1). J Biol Chem. 2002;277:2997-3005 pubmed
Sharma D, Fondell J. Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells. Mol Endocrinol. 2000;14:2001-9 pubmed
Tikkanen M, Carter D, Harris A, Le H, Azorsa D, Meltzer P, et al. Endogenously expressed estrogen receptor and coactivator AIB1 interact in MCF-7 human breast cancer cells. Proc Natl Acad Sci U S A. 2000;97:12536-40 pubmed
Klein E, Wang J, Khalifa B, Gavigan S, Chandraratna R. Recruitment of nuclear receptor corepressor and coactivator to the retinoic acid receptor by retinoid ligands. Influence of DNA-heterodimer interactions. J Biol Chem. 2000;275:19401-8 pubmed
Lanz R, McKenna N, Onate S, Albrecht U, Wong J, Tsai S, et al. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 1999;97:17-27 pubmed
Xu J, Qiu Y, DeMayo F, Tsai S, Tsai M, O Malley B. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science. 1998;279:1922-5 pubmed
Spencer T, Jenster G, Burcin M, Allis C, Zhou J, Mizzen C, et al. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature. 1997;389:194-8 pubmed
图像
图像 1 :
赛默飞世尔 MA1-840 图像 1
产品信息
产品类型 :
抗体
产品名称 :
SRC1单克隆抗体(1135/H4)
目录# :
MA1-840
规格 :
100微升
价格 :
美国420.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
Human, Mouse, Non-human primate
应用 :
ChIP Assay: 5 µL / 10^6 cells, Flow Cytometry: 1 µg / 10^6 cells, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:5,000
物种 :
Human, Mouse, Non-human primate
克隆 :
1135/H4
抗体亚型 :
IgG1
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.
免疫原 :
合成多肽对应于氨基酸残基477-947人的SRC-1
格式 :
液体
应用w/稀释 :
ChIP Assay: 5 µL / 10^6 cells, Flow Cytometry: 1 µg / 10^6 cells, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:5,000
别名 :
ASV; bHLHe42; bHLHe74; class E basic helix-loop-helix protein 74; c-SRC; F-SRC-1; Hin-2 protein; KAT13A; mNRC-1; NCOA1; NCoA-1; Nuclear receptor coactivator 1; nuclear receptor coactivator protein 1; p60-Src; PAX3/NCOA1 fusion protein; Protein Hin-2; Renal carcinoma antigen NY-REN-52; RIP160; Src1; SRC-1; SRC-1 (-Q); SRC-a/NCoA-1; Steroid receptor coactivator 1; steroid receptor coactivator-1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国