产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
HSP70单克隆抗体(W27)
目录 :
MA1-90504
规格 :
500微升
价格 :
425美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
W27
反应物种 :
African green monkey, 仓鼠, 人类, 小鼠, 犬, 牛
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 26
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 2
Yuzefovych Y, Blasczyk R, Huyton T. Oncogenic acidic nuclear phosphoproteins ANP32C/D are novel clients of heat shock protein 90. Biochim Biophys Acta. 2015;1853:2338-48 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Hole S, Pedersen A, Hansen S, Lundqvist J, Yde C, Lykkesfeldt A. New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane. Int J Oncol. 2015;46:1481-90 pubmed 出版商
  • 免疫组化; 人类; 1:50
Vlachos I, Barbatis C, Tsopanomichalou M, Abou Assabeh L, Goumas K, Ginieri Coccossis M, et al. Correlation between depression, anxiety, and polymorphonuclear cells' resilience in ulcerative colitis: the mediating role of heat shock protein 70. BMC Gastroenterol. 2014;14:77 pubmed 出版商
  • 免疫印迹; 人类; 1:500000
Kirkegaard T, Hansen S, Larsen S, Reiter B, Sørensen B, Lykkesfeldt A. T47D breast cancer cells switch from ER/HER to HER/c-Src signaling upon acquiring resistance to the antiestrogen fulvestrant. Cancer Lett. 2014;344:90-100 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Razorenova O, Castellini L, Colavitti R, Edgington L, Nicolau M, Huang X, et al. The apoptosis repressor with a CARD domain (ARC) gene is a direct hypoxia-inducible factor 1 target gene and promotes survival and proliferation of VHL-deficient renal cancer cells. Mol Cell Biol. 2014;34:739-51 pubmed 出版商
  • 免疫组化; 人类; 1:100
Lee H, Lee E, Kim S, Roh M, Jung S, Choi Y. Heat shock protein 70 (HSP70) expression is associated with poor prognosis in intestinal type gastric cancer. Virchows Arch. 2013;463:489-95 pubmed 出版商
  • 免疫组化; 小鼠
Cho K, Haque M, Wang J, Yu M, Hao Y, Qiu S, et al. Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors. PLoS Genet. 2013;9:e1003555 pubmed 出版商
  • 免疫印迹; 人类
Thrane S, Lykkesfeldt A, Larsen M, Sorensen B, Yde C. Estrogen receptor ? is the major driving factor for growth in tamoxifen-resistant breast cancer and supported by HER/ERK signaling. Breast Cancer Res Treat. 2013;139:71-80 pubmed 出版商
  • 免疫组化; 人类; 1:50
Wang G, Gu X, Chen L, Wang Y, Cao B, E Q. Comparison of the expression of 5 heat shock proteins in benign and malignant salivary gland tumor tissues. Oncol Lett. 2013;5:1363-1369 pubmed
  • 免疫印迹; 人类
Nguyen C, Lang B, Chai R, Vieusseux J, Kouspou M, Price J. Heat-shock factor 1 both positively and negatively affects cellular clonogenic growth depending on p53 status. Biochem J. 2013;452:321-9 pubmed 出版商
  • 免疫组化; 人类; 1:100
Abdou A, Maraee A, Reyad W. Immunohistochemical expression of heat shock protein 70 in vitiligo. Ann Diagn Pathol. 2013;17:245-9 pubmed 出版商
  • 免疫印迹; 人类
Stockwell S, Platt G, Barrie S, Zoumpoulidou G, te Poele R, Aherne G, et al. Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling. PLoS ONE. 2012;7:e28568 pubmed 出版商
  • 免疫印迹; 人类
Xu G, Paige J, Jaffrey S. Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Nat Biotechnol. 2010;28:868-73 pubmed 出版商
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
Liu Q, Zhai B, Yang W, Yu L, Dong W, He Y, et al. Abrogation of local cancer recurrence after radiofrequency ablation by dendritic cell-based hyperthermic tumor vaccine. Mol Ther. 2009;17:2049-57 pubmed 出版商
  • 免疫印迹; 犬
Proux Gillardeaux V, Raposo G, Irinopoulou T, Galli T. Expression of the Longin domain of TI-VAMP impairs lysosomal secretion and epithelial cell migration. Biol Cell. 2007;99:261-71 pubmed
  • 免疫印迹; 人类
Juncker Jensen A, Lykkesfeldt A, Worm J, Ralfkiaer U, Espelund U, Jepsen J. Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator. Growth Horm IGF Res. 2006;16:224-39 pubmed
  • 抑制或激活实验; African green monkey; 2 ug/ml
  • 抑制或激活实验; 仓鼠
López T, Lopez S, Arias C. Heat shock enhances the susceptibility of BHK cells to rotavirus infection through the facilitation of entry and post-entry virus replication steps. Virus Res. 2006;121:74-83 pubmed
  • 免疫印迹; 人类
Kang J, Kim S, Hong K. Induction of TSP1 gene expression by heat shock is mediated via an increase in mRNA stability. FEBS Lett. 2006;580:510-6 pubmed
  • 免疫组化; 人类; 1:50
Joo M, Chi J, Lee H. Expressions of HSP70 and HSP27 in hepatocellular carcinoma. J Korean Med Sci. 2005;20:829-34 pubmed
Bayramgurler D, Ozkara S, Apaydin R, Ercin C, Bilen N. Heat shock proteins 60 and 70 expression of cutaneous lichen planus: comparison with normal skin and psoriasis vulgaris. J Cutan Pathol. 2004;31:586-94 pubmed
Menoret A. Purification of recombinant and endogenous HSP70s. Methods. 2004;32:7-12 pubmed
Shatkina L, Mink S, Rogatsch H, Klocker H, Langer G, Nestl A, et al. The cochaperone Bag-1L enhances androgen receptor action via interaction with the NH2-terminal region of the receptor. Mol Cell Biol. 2003;23:7189-97 pubmed
Debure L, Vayssiere J, Rincheval V, Loison F, Le Drean Y, Michel D. Intracellular clusterin causes juxtanuclear aggregate formation and mitochondrial alteration. J Cell Sci. 2003;116:3109-21 pubmed
Elpek G, Karaveli S, Simsek T, Keles N, Aksoy N. Expression of heat-shock proteins hsp27, hsp70 and hsp90 in malignant epithelial tumour of the ovaries. APMIS. 2003;111:523-30 pubmed
Pignatelli D, Ferreira J, Soares P, Costa M, Magalhães M. Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production. Microsc Res Tech. 2003;61:315-23 pubmed
Gerner C, Frohwein U, Gotzmann J, Bayer E, Gelbmann D, Bursch W, et al. The Fas-induced apoptosis analyzed by high throughput proteome analysis. J Biol Chem. 2000;275:39018-26 pubmed
产品信息
产品类型 :
抗体
产品名称 :
HSP70单克隆抗体(W27)
目录# :
MA1-90504
规格 :
500微升
价格 :
425美元
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Bovine, Human, Non-human primate
应用 :
Flow Cytometry: Assay dependent, Immunocytochemistry: Assay-dependent, Immunofluorescence: Assay dependent, Immunohistochemistry (Paraffin): 2-4 µg/mL, Immunoprecipitation: 2 µg/mg, Western Blot: 0.5-1 µg/mL
物种 :
Bovine, Human, Non-human primate
克隆 :
W27
抗体亚型 :
IgG2a
储存 :
4° C, 不冻结
描述 :
HSP70 is a Heat shock protein (HSP) which are expressed in response to various biological stresses, including high temperatures. There are several major families of HSPs that include HSP70, there are HSP90 and HSP100. The HSP70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined. The human HSP70 family members include: HSP70, a protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP72, a 72 kDa protein that is induced exclusively under stress conditions; HSC70, or cognate protein, is a 72 kDa, constitutively expressed, protein which is involved in the uncoating of clathrin coated vesicles; GRP78, or BiP, is a glucose regulated 78 kDa protein localized in the endoplasmic reticulum; and p75, or HSP75, a 75 kDa protein that is found within the mitochondria. Further, HSP70 is encoded by an intronless gene and, in conjunction with other heat shock proteins, HSP70 stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and organelles. HSP70 is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The HSP70 gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
免疫原 :
HSP70蛋白来自HeLa细胞
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay dependent, Immunocytochemistry: Assay-dependent, Immunofluorescence: Assay dependent, Immunohistochemistry (Paraffin): 2-4 µg/mL, Immunoprecipitation: 2 µg/mg, Western Blot: 0.5-1 µg/mL
别名 :
68 kDa heat shock protein; 70 kda heat shock protein-2; 70 kilodalton heat shock protein; 87A; 87A locus; 87C locus; Bb; CG18743; CG31359; CG31359 gene product from transcript CG31359-RA; CG31359-PA; CG31366; CG31366 gene product from transcript CG31366-RA; CG31366-PA; CG31449; CG6489; chaperone; dHsp70; dhsp70Aa; Dmel CG31359; Dmel CG31366; Dmel_CG31359; Dmel_CG31366; Dm-hsp70; DmHSP70AA; DMHSP7D1; dnaK-type molecular chaperone HSP70-1; epididymis secretory protein Li 103; Hcp70.1; heat shock 10kDa protein 1-like; heat shock 70; heat shock 70 kD protein 1; heat shock 70 kD protein 2; heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 1-Hom; Heat shock 70 kDa protein 1L; heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 2; Heat shock 70 kDa protein 3; heat shock 70 kDa-like protein 1; heat shock 70kD protein 1A; heat shock 70kD protein 1B; heat shock 70kD protein 1B (mapped); heat shock 70kD protein-like 1; heat shock 70kDa protein 1A; heat shock 70kDa protein 1B; heat shock 70kDa protein 1-like; Heat shock protein; heat shock protein 1A; heat shock protein 1B; heat shock protein 1-like; Heat Shock Protein 70; heat shock protein 70.1; heat shock protein 70.2; heat shock protein 70-1; Heat shock protein 70-1l; Heat shock protein 70Aa; Heat shock protein 70Ab; Heat shock protein 70Ba; Heat shock protein 70Bb; Heat shock protein 70Bc; heat shock protein cognate 70, testis; heat shock protein family A (Hsp70) member 1 like; heat shock protein family A (Hsp70) member 1A; heat shock protein family A (Hsp70) member 1B; heat shock protein, 70 kDa 1; heat shock protein, 70 kDa 3; heat shock protein-70; heat shock-induced protein; heat shock-related protein hsc70t; heat-shock 70-kilodalton protein 1A; heat-shock 70-kilodalton protein 1B; heat-shock protein 70; Heat-shock-protein-70Aa; Heat-shock-protein-70Bb; HEL S 103; HEL-S-103; hs70; Hsc70t; HSP; Hsp 70; hsp68; hsp70; Hsp-70; HSP70 1; HSP70 1B; HSP70 2; hsp70 87A; hsp70 87C; hsp70 Aa; HSP70 AceyltK77; hsp70(87A); Hsp70(87C); HSP70.1; HSP70.1/2; HSP70.1/HSP70.2; HSP70.2; Hsp70.3; Hsp70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70-1B; HSP70-1L; HSP70-2; Hsp70-3; HSP70-87A7; HSP70-87C1; Hsp70A; hsp70A1; Hsp70A7d; Hsp70Aa; Hsp-70Aa; Hsp70Aa-PA; Hsp70Ab; Hsp70B; Hsp70Ba; Hsp70Bb; Hsp70Bbc; Hsp70Bb-PA; Hsp70Bc; HSP70-HOM; HSP70I; HSP70T; HSP72; Hspa1; HSPA1A; Hspa1b; HSPA1L; Hspa2; Hspa70; HSX70; hum70t; inducible heat shock protein 70; Major heat shock 70 kDa protein Aa; Major heat shock 70 kDa protein Ab; Major heat shock 70 kDa protein Ba; Major heat shock 70 kDa protein Bb; Major heat shock 70 kDa protein Bc; Msh5; protein 70; Spermatid-specific heat shock protein 70
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国