产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
NOTCH1单克隆抗体(A6)
目录 :
MA1-91405
规格 :
500微升
价格 :
美国399.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
A6
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:500; 图 1
Mathan J, Ismail S, McGhee J, McGhee C, Sherwin T. Sphere-forming cells from peripheral cornea demonstrate the ability to repopulate the ocular surface. Stem Cell Res Ther. 2016;7:81 pubmed 出版商
  • 免疫组化; 人类
Krausch M, Kroepil F, Lehwald N, Lachenmayer A, Schott M, Anlauf M, et al. Notch 1 tumor expression is lacking in highly proliferative pancreatic neuroendocrine tumors. Endocrine. 2013;44:182-6 pubmed 出版商
  • 抑制或激活实验; 人类; 10 ug/ml
Del Papa B, Sportoletti P, Cecchini D, Rosati E, Balucani C, Baldoni S, et al. Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction. Eur J Immunol. 2013;43:182-7 pubmed 出版商
  • 流式细胞仪; 小鼠
Perumalsamy L, Marcel N, Kulkarni S, Radtke F, Sarin A. Distinct spatial and molecular features of notch pathway assembly in regulatory T cells. Sci Signal. 2012;5:ra53 pubmed 出版商
  • 抑制或激活实验; 人类; 20 ug/ml
Pei J, Tang Z, Zang G, Yu Y. Blockage of Notch1 signaling modulates the T-helper (Th)1/Th2 cell balance in chronic hepatitis B patients. Hepatol Res. 2010;40:799-805 pubmed 出版商
  • 流式细胞仪; 人类; 1:100
Puget S, Grill J, Valent A, Bieche I, Dantas Barbosa C, Kauffmann A, et al. Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas. J Clin Oncol. 2009;27:1884-92 pubmed 出版商
  • 免疫组化; 人类; 10-20 ug/ml
Kose O, Lalli A, Kutulola A, Odell E, Waseem A. Changes in the expression of stem cell markers in oral lichen planus and hyperkeratotic lesions. J Oral Sci. 2007;49:133-9 pubmed
  • 免疫细胞化学; 人类
  • 酶联免疫吸附测定; 人类
Luty W, Rodeberg D, Parness J, Vyas Y. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates. J Immunol. 2007;179:819-29 pubmed
  • 免疫组化; 人类; 1:100
Su Y, Buchler P, Gazdhar A, Giese N, Reber H, Hines O, et al. Pancreatic regeneration in chronic pancreatitis requires activation of the notch signaling pathway. J Gastrointest Surg. 2006;10:1230-41; discussion 1242 pubmed
  • 免疫印迹; 小鼠; 2 ug/ml
Bheeshmachar G, Purushotaman D, Sade H, Gunasekharan V, Rangarajan A, Sarin A. Evidence for a role for notch signaling in the cytokine-dependent survival of activated T cells. J Immunol. 2006;177:5041-50 pubmed
  • 免疫组化; 人类
Blaukovitsch M, Halbwedl I, Kothmaier H, Gogg Kammerer M, Popper H. Sarcomatoid carcinomas of the lung--are these histogenetically heterogeneous tumors?. Virchows Arch. 2006;449:455-61 pubmed
  • 免疫组化; 人类; 1:100
Buchler P, Gazdhar A, Schubert M, Giese N, Reber H, Hines O, et al. The Notch signaling pathway is related to neurovascular progression of pancreatic cancer. Ann Surg. 2005;242:791-800, discussion 800-1 pubmed
  • 免疫组化; 人类; 1:250
Morsczeck C, Gotz W, Schierholz J, Zeilhofer F, Kuhn U, Mohl C, et al. Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth. Matrix Biol. 2005;24:155-65 pubmed
  • 免疫组化; 人类; 1:200
  • 免疫印迹; 人类; 1:100
Purow B, Haque R, Noel M, Su Q, Burdick M, Lee J, et al. Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation. Cancer Res. 2005;65:2353-63 pubmed
  • 抑制或激活实验; 小鼠
Sakamoto K, Chao W, Katsube K, Yamaguchi A. Distinct roles of EGF repeats for the Notch signaling system. Exp Cell Res. 2005;302:281-91 pubmed
Cui X, Hu Q, Tekaya M, Shimoda Y, Ang B, Nie D, et al. NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes. J Biol Chem. 2004;279:25858-65 pubmed
产品信息
产品类型 :
抗体
产品名称 :
NOTCH1单克隆抗体(A6)
目录# :
MA1-91405
规格 :
500微升
价格 :
美国399.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:50
物种 :
人类, 小鼠
克隆 :
A6
抗体亚型 :
IgG2b
储存 :
4° C, 不冻结
描述 :
The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).
免疫原 :
Recombinant protein encoding the ligand binding region of human Notch 1
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:50
别名 :
9930111A19Rik; AOS5; AOVD1; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; notch receptor 1; Notch1; p300; RP23-306D20.12; RP23-306D20.12-001; Tan1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国