产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
VCP单克隆抗体(5)
目录 :
MA3-004
规格 :
100微克
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
5
反应物种 :
酵母菌目, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 26
出版应用/物种/样本/稀释 | 参考文献 |
---|---|
| |
| |
| |
| |
| |
| Mori F, Watanabe Y, Miki Y, Tanji K, Odagiri S, Eto K, et al. Ubiquitin-negative, eosinophilic neuronal cytoplasmic inclusions associated with stress granules and autophagy: an immunohistochemical investigation of two cases. Neuropathology. 2014;34:140-7 pubmed
|
| |
| |
| |
| Rodriguez Ortiz C, Hoshino H, Cheng D, Liu Yescevitz L, Blurton Jones M, Wolozin B, et al. Neuronal-specific overexpression of a mutant valosin-containing protein associated with IBMPFD promotes aberrant ubiquitin and TDP-43 accumulation and cognitive dysfunction in transgenic mice. Am J Pathol. 2013;183:504-15 pubmed 出版商
|
| |
| |
| |
| |
| |
| Tresse E, Salomons F, Vesa J, Bott L, Kimonis V, Yao T, et al. VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD. Autophagy. 2010;6:217-27 pubmed
|
| |
| Greenberg S, Watts G, Kimonis V, Amato A, Pinkus J. Nuclear localization of valosin-containing protein in normal muscle and muscle affected by inclusion-body myositis. Muscle Nerve. 2007;36:447-54 pubmed
|
| Saffar A, Alphonse M, Shan L, Hayglass K, Simons F, Gounni A. IgE modulates neutrophil survival in asthma: role of mitochondrial pathway. J Immunol. 2007;178:2535-41 pubmed
|
Vij N, Fang S, Zeitlin P. Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels: therapeutic implications. J Biol Chem. 2006;281:17369-78 pubmed
|
图像
图像 1 :
Immunofluorescent analysis of VCP using VCP Monoclonal antibody (5) (Product# MA3-004) shows staining in HeLa cells. VCP staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing VCP (Product# MA3-004) at a dilution of 1:20-1:200 over night at 4 ?C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product# 35552 for GAR, Product# 35503 for GAM). Images were taken at 60X magnification.
产品信息
产品类型 :
抗体
产品名称 :
VCP单克隆抗体(5)
目录# :
MA3-004
规格 :
100微克
价格 :
美国425.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Flow Cytometry: 1/400, Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Frozen): 1:500, Immunohistochemistry (Paraffin): 1:500, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
物种 :
人类, 小鼠, 大鼠
克隆 :
5
抗体亚型 :
IgG2a
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
免疫原 :
Synthetic peptide corresponding to residues C G(792) G S V Y T E D N D D D L Y G(806) of mouse VCP.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1/400, Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Frozen): 1:500, Immunohistochemistry (Paraffin): 1:500, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
别名 :
15S Mg(2+)-ATPase p97 subunit; 3110001E05; AAA ATPase p97; ALS14; CDC48; cell division cycle gene CDC48; CMT2Y; epididymis luminal protein 220; epididymis secretory protein Li 70; HEL-220; HEL-S-70; homolog of yeast cdc48; IBMPFD; IBMPFD1; Inv protein; or HEL-S-70; p97; p97 atpase; p97/VCP; Protein CDC48; si:ch211-113n10.2; TER ATPase; TERA; transitional endoplasmic reticulum ATPase; valosin containing protein; valosin-containing protein; Vcp; wu:fd16d05; wu:fj63d11; yeast Cdc48p homolog
更多信息或购买 :
公司信息
赛默飞世尔