产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PDI单克隆抗体(RL77)
目录 :
MA3-018
规格 :
100微升
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
RL77
反应物种 :
中国人仓鼠, African green monkey, 人类, 小鼠, 大鼠, 犬, pigs , 非洲爪蛙, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 40
出版应用/物种/样本/稀释 | 参考文献 |
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| Van Damme P, Kalvik T, Starheim K, Jonckheere V, Myklebust L, Menschaert G, et al. A Role for Human N-alpha Acetyltransferase 30 (Naa30) in Maintaining Mitochondrial Integrity. Mol Cell Proteomics. 2016;15:3361-3372 pubmed
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| Labriola L, Ferreira G, Montor W, Demasi M, Pimenta D, Lojudice F, et al. Prolactin-induced changes in protein expression in human pancreatic islets. Mol Cell Endocrinol. 2007;264:16-27 pubmed
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| Ou W, Silver J. Role of protein disulfide isomerase and other thiol-reactive proteins in HIV-1 envelope protein-mediated fusion. Virology. 2006;350:406-17 pubmed
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| O Donnell V, LaRocco M, Duque H, Baxt B. Analysis of foot-and-mouth disease virus internalization events in cultured cells. J Virol. 2005;79:8506-18 pubmed
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| Stillemark Billton P, Beck C, Boren J, Olofsson S. Relation of the size and intracellular sorting of apoB to the formation of VLDL 1 and VLDL 2. J Lipid Res. 2005;46:104-14 pubmed
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Schultz Norton J, McDonald W, Yates J, Nardulli A. Protein disulfide isomerase serves as a molecular chaperone to maintain estrogen receptor alpha structure and function. Mol Endocrinol. 2006;20:1982-95 pubmed
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Minogue P, Liu X, Ebihara L, Beyer E, Berthoud V. An aberrant sequence in a connexin46 mutant underlies congenital cataracts. J Biol Chem. 2005;280:40788-95 pubmed
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Wierenga C, Ibata K, Turrigiano G. Postsynaptic expression of homeostatic plasticity at neocortical synapses. J Neurosci. 2005;25:2895-905 pubmed
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Tao Y, Johnson N, Segaloff D. Constitutive and agonist-dependent self-association of the cell surface human lutropin receptor. J Biol Chem. 2004;279:5904-14 pubmed
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Knoblach B, Keller B, Groenendyk J, Aldred S, Zheng J, Lemire B, et al. ERp19 and ERp46, new members of the thioredoxin family of endoplasmic reticulum proteins. Mol Cell Proteomics. 2003;2:1104-19 pubmed
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Shames I, Fraser A, Colby J, Orfali W, Snipes G. Phenotypic differences between peripheral myelin protein-22 (PMP22) and myelin protein zero (P0) mutations associated with Charcot-Marie-Tooth-related diseases. J Neuropathol Exp Neurol. 2003;62:751-64 pubmed
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Clark R, Li S, Pearson D, Leidal K, Clark J, Denning G, et al. Regulation of calreticulin expression during induction of differentiation in human myeloid cells. Evidence for remodeling of the endoplasmic reticulum. J Biol Chem. 2002;277:32369-78 pubmed
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Sargsyan E, Baryshev M, Szekely L, Sharipo A, Mkrtchian S. Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex. J Biol Chem. 2002;277:17009-15 pubmed
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Li P, Nakanishi A, Clark S, Kasamatsu H. Formation of transitory intrachain and interchain disulfide bonds accompanies the folding and oligomerization of simian virus 40 Vp1 in the cytoplasm. Proc Natl Acad Sci U S A. 2002;99:1353-8 pubmed
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Torres V, Cai Y, Chen X, Wu G, Geng L, Cleghorn K, et al. Vascular expression of polycystin-2. J Am Soc Nephrol. 2001;12:1-9 pubmed
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Colby J, Nicholson R, Dickson K, Orfali W, Naef R, Suter U, et al. PMP22 carrying the trembler or trembler-J mutation is intracellularly retained in myelinating Schwann cells. Neurobiol Dis. 2000;7:561-73 pubmed
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Berryman M, Bretscher A. Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli. Mol Biol Cell. 2000;11:1509-21 pubmed
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Bennett T, Edwards B, Sklar L, Rogelj S. Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes. J Immunol. 2000;164:4120-9 pubmed
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Basu S, Srivastava P. Calreticulin, a peptide-binding chaperone of the endoplasmic reticulum, elicits tumor- and peptide-specific immunity. J Exp Med. 1999;189:797-802 pubmed
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Kuznetsov G, Chen L, Nigam S. Several endoplasmic reticulum stress proteins, including ERp72, interact with thyroglobulin during its maturation. J Biol Chem. 1994;269:22990-5 pubmed
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Kaetzel C, Rao C, Lamm M. Protein disulphide-isomerase from human placenta and rat liver. Purification and immunological characterization with monoclonal antibodies. Biochem J. 1987;241:39-47 pubmed
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图像
图像 1 :
Immunofluorescent analysis of PDI using anti-PDI monoclonal antibody (Product# MA3-018) shows staining in HMVEC Cells.
产品信息
产品类型 :
抗体
产品名称 :
PDI单克隆抗体(RL77)
目录# :
MA3-018
规格 :
100微升
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
狗, 仓鼠, 人类, 小鼠, 猪, 大鼠, 非洲爪蛙
应用 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry: 1:100, Immunoprecipitation: Assay-dependent, Western Blot: 1:200-1:2,000
物种 :
狗, 仓鼠, 人类, 小鼠, 猪, 大鼠, 非洲爪蛙
克隆 :
RL77
抗体亚型 :
IgG2b
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Protein disulfide isomerase (PDI) is a multifunctional protein that catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, the protein seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. It may therefore cause structural modifications of exofacial proteins. Inside the cell, PDI seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, it functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, it facilitates aggregation (anti-chaperone activity). PDI may be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. It also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.
免疫原 :
纯化大鼠PDI蛋白
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry: 1:100, Immunoprecipitation: Assay-dependent, Western Blot: 1:200-1:2,000
别名 :
1810041F13Rik; AI661267; CaO19.12595; cellular thyroid hormone binding protein; cellular thyroid hormone-binding protein; CLCRP1; collagen prolyl 4-hydroxylase beta; DSI; Endoplasmic reticulum resident protein 59; Eps1p; ER protein 59; ERBA2L; ERp59; GIT; glutathione-insulin transhydrogenase; I79_002399; LOW QUALITY PROTEIN: protein disulfide-isomerase A2; MFP1; P4HB; p4hb.L; P4Hbeta; p55; p58; Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDA2; PDI; PDI (E.C.5.3.4.1); PDI1; PDI1P; Pdia1; pdia2; pdia2.L; PDIP; Pdipl; PDIR; PHDB; PO4DB; PO4HB; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; PROHB; prolyl 4-hydroxylase beta polypeptide; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase, beta polypeptide L homeolog; prolyl 4-hydroxylase, beta polypeptide; prolyl 4-hydroxylase, beta subunit; protein disulfide isomerase; protein disulfide isomerase (pancreas) like; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); protein disulfide isomerase A2; protein disulfide isomerase associated 2; protein disulfide isomerase family A member 2; protein disulfide isomerase family A member 2 L homeolog; protein disulfide isomerase family A, member 1; protein disulfide isomerase family A, member 2; protein disulfide isomerase PDI1; protein disulfide isomerase, pancreatic; protein disulfide isomerase/oxidoreductase; protein disulfide isomerase-associated 1; protein disulfide isomerase-associated 2; protein disulfide-isomerase; Protein disulfide-isomerase A2; protocollagen hydroxylase; Rho GDP dissociation inhibitor gamma; testicular secretory protein Li 32; Thbp; Thioredoxin-related glycoprotein 1; thyroid hormone-binding protein p55; TRG1; XELAEV_18043753mg; XELAEV_18045582mg; XPDIp; YCL043C; YCL313; YCL43C
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公司信息
赛默飞世尔