产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
核纤层蛋白A/C单克隆抗体(mab636)
目录 :
MA3-1000
规格 :
200微升
价格 :
美国395.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
mab636
反应物种 :
人类, , pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 31
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 牛; 1:100; 图 3a
  • 免疫印迹; 人类; 图 3c
Heo S, Driscoll T, Thorpe S, Nerurkar N, Baker B, Yang M, et al. Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 2
Derussy B, Boland M, Tandon R. Human Cytomegalovirus pUL93 Links Nucleocapsid Maturation and Nuclear Egress. J Virol. 2016;90:7109-7117 pubmed 出版商
  • 免疫印迹; 人类; 图 9
Eisch V, Lu X, Gabriel D, Djabali K. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts. Oncotarget. 2016;7:24700-18 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Liu R, Li S, Garcia E, Glubrecht D, Poon H, Easaw J, et al. Association between cytoplasmic CRABP2, altered retinoic acid signaling, and poor prognosis in glioblastoma. Glia. 2016;64:963-76 pubmed 出版商
  • 免疫细胞化学; 人类
Sörgel S, Fraedrich K, Votteler J, Thomas M, Stamminger T, Schubert U. Perinuclear localization of the HIV-1 regulatory protein Vpr is important for induction of G2-arrest. Virology. 2012;432:444-51 pubmed 出版商
  • 免疫印迹; 人类; 1:200
Lee J, Zhou S, Smas C. Identification of RANBP16 and RANBP17 as novel interaction partners for the bHLH transcription factor E12. J Cell Biochem. 2010;111:195-206 pubmed 出版商
  • 免疫印迹; 人类
Lindsay A, McCaffrey M. Myosin Vb localises to nucleoli and associates with the RNA polymerase I transcription complex. Cell Motil Cytoskeleton. 2009;66:1057-72 pubmed 出版商
Betlej G, Z x105 bek T, Lewi x144 ska A, B x142 oniarz D, Rzeszutek I, Wnuk M. RNA 5-methylcytosine status is associated with DNMT2/TRDMT1 nuclear localization in osteosarcoma cell lines. J Bone Oncol. 2022;36:100448 pubmed 出版商
Li D, Fu Z, Dong C, Song Y. Downregulation of circATXN7 represses non-small cell lung cancer growth by releasing miR-7-5p. Thorac Cancer. 2022;13:1597-1610 pubmed 出版商
Guo D, Daman K, Chen J, Shi M, Yan J, Matijasevic Z, et al. iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling. elife. 2022;11: pubmed 出版商
Ning J, Yang R, Wang H, Cui L. HMGB1 enhances chemotherapy resistance in multiple myeloma cells by activating the nuclear factor-κB pathway. Exp Ther Med. 2021;22:705 pubmed 出版商
Bentebbal S, Meqbel B, Salter A, Allan V, Burke B, Horn H. A human infertility-associated KASH5 variant promotes mitochondrial localization. Sci Rep. 2021;11:10133 pubmed 出版商
Gallego Valle J, Gil Manso S, Pita A, Bernaldo de Quirós E, López Esteban R, Martínez Bonet M, et al. Ectopic FOXP3 Expression in Combination with TGF-β1 and IL-2 Stimulation Generates Limited Suppressive Function in Human Primary Activated Thymocytes Ex Vivo. Biomedicines. 2021;9: pubmed 出版商
Yang F, Liu Q, Chen Y, Ye H, Wang H, Zeng S. Integrative Proteomic and Phosphoproteomic Analyses of Granulosa Cells During Follicular Atresia in Porcine. Front Cell Dev Biol. 2020;8:624985 pubmed 出版商
Rannou A, Toumaniantz G, Larcher T, Leroux I, Ledevin M, Hivonnait A, et al. Human MuStem Cell Grafting into Infarcted Rat Heart Attenuates Adverse Tissue Remodeling and Preserves Cardiac Function. Mol Ther Methods Clin Dev. 2020;18:446-463 pubmed 出版商
Alghanem B, Ali R, Nehdi A, Al Zahrani H, Altolayyan A, Shaibah H, et al. Proteomics Profiling of KAIMRC1 in Comparison to MDA-MB231 and MCF-7. Int J Mol Sci. 2020;21: pubmed 出版商
Kwon J, Vankara A, Ettyreddy A, Bohning J, Gersbach C. Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators. Stem Cell Reports. 2020;14:755-769 pubmed 出版商
Hou Y, Xie W, Yu L, Camacho L, Nie C, Zhang M, et al. Surface Roughness Gradients Reveal Topography-Specific Mechanosensitive Responses in Human Mesenchymal Stem Cells. Small. 2020;16:e1905422 pubmed 出版商
Joshi R, Stadler C, Lehmann R, Lehtiö J, Tegner J, Schmidt A, et al. TcellSubC: An Atlas of the Subcellular Proteome of Human T Cells. Front Immunol. 2019;10:2708 pubmed 出版商
Liu C, Arnold R, Henriques G, Djabali K. Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells. Cells. 2019;8: pubmed 出版商
Vo T, Jain S, Burchett R, Monckton E, Godbout R. A positive feedback loop involving nuclear factor IB and calpain 1 suppresses glioblastoma cell migration. J Biol Chem. 2019;294:12638-12654 pubmed 出版商
Sakowicz A, Lisowska M, Biesiada L, Płuciennik E, Gach A, Rybak Krzyszkowska M, et al. Placental Expression of NEMO Protein in Normal Pregnancy and Preeclampsia. Dis Markers. 2019;2019:8418379 pubmed 出版商
Adam I, Dewi D, Mooiweer J, Sadik A, Mohapatra S, Berdel B, et al. Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation. Oncoimmunology. 2018;7:e1486353 pubmed 出版商
Xu J, Francis A, Meuser M, Mankowski M, Ptak R, Rashad A, et al. Exploring Modifications of an HIV-1 Capsid Inhibitor: Design, Synthesis, and Mechanism of Action. J Drug Des Res. 2018;5: pubmed
Koufaris C, Nilsson R. Protein interaction and functional data indicate MTHFD2 involvement in RNA processing and translation. Cancer Metab. 2018;6:12 pubmed 出版商
Ibba G, Piu C, Uleri E, Serra C, Dolei A. Disruption by SaCas9 Endonuclease of HERV-Kenv, a Retroviral Gene with Oncogenic and Neuropathogenic Potential, Inhibits Molecules Involved in Cancer and Amyotrophic Lateral Sclerosis. Viruses. 2018;10: pubmed 出版商
Wang X, Liu H, Zhu M, Cao C, Xu Z, Tsatskis Y, et al. Mechanical stability of the cell nucleus - roles played by the cytoskeleton in nuclear deformation and strain recovery. J Cell Sci. 2018;131: pubmed 出版商
Amador Cañizares Y, Bernier A, Wilson J, Sagan S. miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5' end from the cellular pyrophosphatases, DOM3Z and DUSP11. Nucleic Acids Res. 2018;46:5139-5158 pubmed 出版商
Naranjo J, Zhang H, Villar D, González P, Dopazo X, Morón Oset J, et al. Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease. J Clin Invest. 2016;126:627-38 pubmed 出版商
Elbashir S, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411:494-8 pubmed
Röber R, Gieseler R, Peters J, Weber K, Osborn M. Induction of nuclear lamins A/C in macrophages in in vitro cultures of rat bone marrow precursor cells and human blood monocytes, and in macrophages elicited in vivo by thioglycollate stimulation. Exp Cell Res. 1990;190:185-94 pubmed
图像
图像 1 :
赛默飞世尔 MA3-1000 图像 1
Immunofluorescent analysis of Lamin A/C using Lamin A/C Monoclonal Antibody (mab636) (Product# MA3-1000 ) shows staining in Hela Cells. Lamin A/C (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with an antibody recognizing Lamin A/C (Product# MA3-1000 ) at a dilution of 1:20 over night at 4 ?C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product# 35552 for GAR, Product# 35503 for GAM). Images were taken at 60X magnification.
产品信息
产品类型 :
抗体
产品名称 :
核纤层蛋白A/C单克隆抗体(mab636)
目录# :
MA3-1000
规格 :
200微升
价格 :
美国395.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
牛, 人类, 猪
应用 :
Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:100, Western Blot: 1:100-1:2,000
物种 :
牛, 人类, 猪
克隆 :
mab636
抗体亚型 :
IgG2b
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).
免疫原 :
Porcine lamin preparation.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:100, Western Blot: 1:100-1:2,000
别名 :
70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国