产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
钙调蛋白单克隆抗体(6D4)
目录 :
MA3-918
规格 :
100微升
价格 :
美国375.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6D4
反应物种 :
Koelliker's sea pansy, Acropora digitifera, 人类, 小鼠, 大鼠, 鸡, 牛
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠
Ferretti R, Marques M, Khurana T, Santo Neto H. Expression of calcium-buffering proteins in rat intrinsic laryngeal muscles. Physiol Rep. 2015;3: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100
Bazwinsky Wutschke I, Muhlbauer E, Albrecht E, Peschke E. Calcium-signaling components in rat insulinoma ?-cells (INS-1) and pancreatic islets are differentially influenced by melatonin. J Pineal Res. 2014;56:439-49 pubmed 出版商
  • 免疫组化; 大鼠; 1:50
  • 免疫印迹; 大鼠; 1:1000
Bazwinsky Wutschke I, Wolgast S, Muhlbauer E, Peschke E. Distribution patterns of calcium-binding proteins in pancreatic tissue of non-diabetic as well as type 2 diabetic rats and in rat insulinoma beta-cells (INS-1). Histochem Cell Biol. 2010;134:115-27 pubmed 出版商
  • 免疫印迹; Koelliker's sea pansy; 1:1000
Morita M, Kitamura M, Nakajima A, Sri Susilo E, Takemura A, Okuno M. Regulation of sperm flagellar motility activation and chemotaxis caused by egg-derived substance(s) in sea cucumber. Cell Motil Cytoskeleton. 2009;66:202-14 pubmed 出版商
  • 免疫印迹; Acropora digitifera; 1:1000
Morita M, Iguchi A, Takemura A. Roles of calmodulin and calcium/calmodulin-dependent protein kinase in flagellar motility regulation in the coral Acropora digitifera. Mar Biotechnol (NY). 2009;11:118-23 pubmed 出版商
Glover L, Heffron J, Ohlendieck K. Increased sensitivity of the ryanodine receptor to halothane-induced oligomerization in malignant hyperthermia-susceptible human skeletal muscle. J Appl Physiol (1985). 2004;96:11-8 pubmed
Hulen D, Baron A, Salisbury J, Clarke M. Production and specificity of monoclonal antibodies against calmodulin from Dictyostelium discoideum. Cell Motil Cytoskeleton. 1991;18:113-22 pubmed
Coling D, Salisbury J. Characterization of the calcium-binding contractile protein centrin from Tetraselmis striata (Pleurastrophyceae). J Protozool. 1992;39:385-91 pubmed
Zhu Q, Clarke M. Association of calmodulin and an unconventional myosin with the contractile vacuole complex of Dictyostelium discoideum. J Cell Biol. 1992;118:347-58 pubmed
图像
图像 1 :
赛默飞世尔 MA3-918 图像 1
产品信息
产品类型 :
抗体
产品名称 :
钙调蛋白单克隆抗体(6D4)
目录# :
MA3-918
规格 :
100微升
价格 :
美国375.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
细菌, 牛, 鸡, 人类, 大鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Western Blot: 1:2,000
物种 :
细菌, 牛, 鸡, 人类, 大鼠
克隆 :
6D4
抗体亚型 :
IgG1
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells. With the capacity to bind up to four calcium ions, this 17 kDa protein acts as an important intracellular receptor for regulatory calcium signals. As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins. It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases. Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations. Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. They are identified by their occurrence in the cytosol or on membranes facing the cytosol and by a high affinity for calcium. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters.
免疫原 :
Calmodulin purified from Dictyostelium discoideum.
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Western Blot: 1:2,000
别名 :
1500001E21Rik; 2310037J09Rik; AI256814; AI327027; AI461935; AI649108; AL024000; AL024017; AY314008; calcium binding gene, DD112; calcium-binding protein Dd112; CALM; CALM 1; CALM1; CALM2; Calm3; Calm4; Calm5; CALML2; Calmodulin; calmodulin 1; calmodulin 1 (phosphorylase kinase, delta); calmodulin 2; calmodulin 2 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); calmodulin 4; calmodulin 5; Calmodulin III; calmodulin-1; Calmodulin-2; calmodulin-3; Calmodulin-4; calmodulin-like; calmodulin-like protein; calmodulin-like protein (neoCaM); caM; CAM1; Cam2; CAM3; CaMA; Camb; CamC; CaMI; CAMII; CAMIII; CPVT4; DD112; DD132; epididymis secretory protein Li 72; HEL-S-72; hypothetical protein; LP7057 protein; LQT14; LQT15; MGC128137 protein; neo-calmodulin; NeoCaM; PHKD; PHKD2; PHKD3; phosphorylase kinase delta; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 2; prepro-calmodulin 3; R75142; RNCAMIII; Scarf; Scarf2; similar to calmodulin; skin calmodulin-related factor
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国