产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Phospholamban Monoclonal Antibody (2D12)
目录 :
MA3-922
规格 :
100微克
价格 :
美国399.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2D12
反应物种 :
豚鼠, 人类, 小鼠, 大鼠, 犬, 鸡, pigs , 家羊, domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 151
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; domestic rabbit; 1:2000; 图 5
Chang S, Chuang H, Chen Y, Kao Y, Lin Y, Yeh Y, et al. Heart failure modulates electropharmacological characteristics of sinoatrial nodes. Exp Ther Med. 2017;13:771-779 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Fajardo V, Gamu D, Mitchell A, Bloemberg D, Bombardier E, Chambers P, et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE. 2017;12:e0173708 pubmed 出版商
  • 免疫印迹; 大鼠; 图 8b
Kirschmer N, Bandleon S, von Ehrlich Treuenstätt V, Hartmann S, Schaaf A, Lamprecht A, et al. TRPC4? and TRPC4? Similarly Affect Neonatal Cardiomyocyte Survival during Chronic GPCR Stimulation. PLoS ONE. 2016;11:e0168446 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2c
Fu Q, Hu Y, Wang Q, Liu Y, Li N, Xu B, et al. High-fat diet induces protein kinase A and G-protein receptor kinase phosphorylation of β2 -adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts. J Physiol. 2017;595:1973-1986 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 1
Fajardo V, Smith I, Bombardier E, Chambers P, Quadrilatero J, Tupling A. Diaphragm assessment in mice overexpressing phospholamban in slow-twitch type I muscle fibers. Brain Behav. 2016;6:e00470 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 s1
Sadredini M, Danielsen T, Aronsen J, Manotheepan R, Hougen K, Sjaastad I, et al. Beta-Adrenoceptor Stimulation Reveals Ca2+ Waves and Sarcoplasmic Reticulum Ca2+ Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure. PLoS ONE. 2016;11:e0153887 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 s9a
Nelson B, Makarewich C, Anderson D, Winders B, Troupes C, Wu F, et al. A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle. Science. 2016;351:271-5 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
Fajardo V, Bombardier E, McMillan E, TRAN K, Wadsworth B, Gamu D, et al. Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype. Dis Model Mech. 2015;8:999-1009 pubmed 出版商
  • 免疫印迹; 大鼠; 图 5
Dalpiaz P, Lamas A, Caliman I, Ribeiro R, Abreu G, Moyses M, et al. Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats. PLoS ONE. 2015;10:e0127515 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20000
Major J, Salih M, Tuana B. Interplay between the E2F pathway and β-adrenergic signaling in the pathological hypertrophic response of myocardium. J Mol Cell Cardiol. 2015;84:179-90 pubmed 出版商
  • 免疫印迹; domestic rabbit
Moshal K, Zhang Z, Roder K, Kim T, Cooper L, Patedakis Litvinov B, et al. Progesterone modulates SERCA2a expression and function in rabbit cardiomyocytes. Am J Physiol Cell Physiol. 2014;307:C1050-7 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 5
Freire P, Alves C, Deus A, Leopoldo A, Leopoldo A, Silva D, et al. Obesity does not lead to imbalance between myocardial phospholamban phosphorylation and dephosphorylation. Arq Bras Cardiol. 2014;103:41-50 pubmed
  • 免疫印迹; 小鼠
Holemans T, Vandecaetsbeek I, Wuytack F, Vangheluwe P. Measuring Ca2+-dependent Ca2+-uptake activity in the mouse heart. Cold Spring Harb Protoc. 2014;2014:876-86 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Fioresi M, Simões M, Furieri L, Broseghini Filho G, Vescovi M, Stefanon I, et al. Chronic lead exposure increases blood pressure and myocardial contractility in rats. PLoS ONE. 2014;9:e96900 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Faria T, Costa G, Almenara C, Angeli J, Vassallo D, Stefanon I, et al. Chronic exposure to low doses of HgCl2 avoids calcium handling impairment in the right ventricle after myocardial infarction in rats. PLoS ONE. 2014;9:e95639 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Mourouzis I, Mantzouratou P, Galanopoulos G, Kostakou E, Dhalla A, Belardinelli L, et al. The beneficial effects of ranolazine on cardiac function after myocardial infarction are greater in diabetic than in nondiabetic rats. J Cardiovasc Pharmacol Ther. 2014;19:457-69 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Sivagangabalan G, Nazzari H, Bignolais O, Maguy A, Naud P, Farid T, et al. Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts. PLoS ONE. 2014;9:e82179 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:250; 图 4
  • 免疫沉淀; 人类; 图 6
  • 免疫印迹; 人类; 1:2000; 图 3
Fajardo V, Bombardier E, Vigna C, Devji T, Bloemberg D, Gamu D, et al. Co-expression of SERCA isoforms, phospholamban and sarcolipin in human skeletal muscle fibers. PLoS ONE. 2013;8:e84304 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10000
Haddad R, Kasneci A, Sebag I, Chalifour L. Cardiac structure/function, protein expression, and DNA methylation are changed in adult female mice exposed to diethylstilbestrol in utero. Can J Physiol Pharmacol. 2013;91:741-9 pubmed 出版商
  • 免疫印迹; 大鼠
Yi T, Vick J, Vecchio M, Begin K, Bell S, Delay R, et al. Identifying cellular mechanisms of zinc-induced relaxation in isolated cardiomyocytes. Am J Physiol Heart Circ Physiol. 2013;305:H706-15 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Mourouzis I, Kostakou E, Galanopoulos G, Mantzouratou P, Pantos C. Inhibition of thyroid hormone receptor ?1 impairs post-ischemic cardiac performance after myocardial infarction in mice. Mol Cell Biochem. 2013;379:97-105 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10000
Patel B, Raad M, Sebag I, Chalifour L. Lifelong exposure to bisphenol a alters cardiac structure/function, protein expression, and DNA methylation in adult mice. Toxicol Sci. 2013;133:174-85 pubmed 出版商
  • 免疫印迹; 大鼠; 0.5 ug/ml
Ribeiro R, Potratz F, Pavan B, Forechi L, Lima F, Fiorim J, et al. Carvedilol prevents ovariectomy-induced myocardial contractile dysfunction in female rat. PLoS ONE. 2013;8:e53226 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10000
Calvé A, Noiles W, Sebag I, Chalifour L. The impact of doxorubicin and dexrazoxane injection of prepubertal female rats on pregnancy outcome and cardiac function postpartum. Can J Physiol Pharmacol. 2012;90:1527-34 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10000
Haddad R, Kasneci A, Mepham K, Sebag I, Chalifour L. Gestational exposure to diethylstilbestrol alters cardiac structure/function, protein expression and DNA methylation in adult male mice progeny. Toxicol Appl Pharmacol. 2013;266:27-37 pubmed 出版商
  • 免疫印迹; pigs ; 1:3000
Klug D, Boulé S, Wissocque L, Montaigne D, Marechal X, Hassoun S, et al. Right ventricular pacing with mechanical dyssynchrony causes apoptosis interruptus and calcium mishandling. Can J Cardiol. 2013;29:510-8 pubmed 出版商
  • 免疫印迹; pigs
Cutler M, Wan X, Plummer B, Liu H, Deschenes I, Laurita K, et al. Targeted sarcoplasmic reticulum Ca2+ ATPase 2a gene delivery to restore electrical stability in the failing heart. Circulation. 2012;126:2095-104 pubmed 出版商
  • 免疫印迹; 人类
Middlekauff H, Vigna C, Verity M, Fonarow G, Horwich T, Hamilton M, et al. Abnormalities of calcium handling proteins in skeletal muscle mirror those of the heart in humans with heart failure: a shared mechanism?. J Card Fail. 2012;18:724-33 pubmed 出版商
  • 免疫印迹; 大鼠; 1:3000
ZHANG Y, Tang Y, Zhang M, Chen J, Zhou Q, Sun Y, et al. Fosinopril attenuates the doxorubicin-induced cardiomyopathy by restoring the function of sarcoplasmic reticulum. Cell Biochem Biophys. 2012;64:205-11 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Calvé A, Haddad R, Barama S, Meilleur M, Sebag I, Chalifour L. Cardiac response to doxorubicin and dexrazoxane in intact and ovariectomized young female rats at rest and after swim training. Am J Physiol Heart Circ Physiol. 2012;302:H2048-57 pubmed 出版商
  • 免疫印迹; domestic rabbit
Odening K, Choi B, Liu G, Hartmann K, Ziv O, Chaves L, et al. Estradiol promotes sudden cardiac death in transgenic long QT type 2 rabbits while progesterone is protective. Heart Rhythm. 2012;9:823-32 pubmed 出版商
  • 免疫印迹; 小鼠
Sjåland C, Lunde P, Swift F, Munkvik M, Ericsson M, Lunde M, et al. Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle. J Physiol. 2011;589:6139-55 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Mostarda C, Moraes Silva I, Moreira E, Medeiros A, Piratello A, Consolim Colombo F, et al. Baroreflex sensitivity impairment is associated with cardiac diastolic dysfunction in rats. J Card Fail. 2011;17:519-25 pubmed 出版商
  • 免疫印迹; 大鼠; 1 ug/ml
Paigel A, Ribeiro R, Fernandes A, Targueta G, Vassallo D, Stefanon I. Myocardial contractility is preserved early but reduced late after ovariectomy in young female rats. Reprod Biol Endocrinol. 2011;9:54 pubmed 出版商
  • 免疫组化; 小鼠; 1:500
  • 免疫印迹; 小鼠; 1:500
Rodrigues B, Rosa K, Medeiros A, Schaan B, Brum P, de Angelis K, et al. Hyperglycemia can delay left ventricular dysfunction but not autonomic damage after myocardial infarction in rodents. Cardiovasc Diabetol. 2011;10:26 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Ferreira J, Moreira J, Campos J, Pereira M, Mattos K, Coelho M, et al. Angiotensin receptor blockade improves the net balance of cardiac Ca(2+) handling-related proteins in sympathetic hyperactivity-induced heart failure. Life Sci. 2011;88:578-85 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Horiuchi Hirose M, Kashihara T, Nakada T, Kurebayashi N, Shimojo H, Shibazaki T, et al. Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes. Am J Physiol Heart Circ Physiol. 2011;300:H978-88 pubmed 出版商
  • 免疫印迹; 人类; 1:2500
Hamdani N, Borbely A, Veenstra S, Kooij V, Vrydag W, Zaremba R, et al. More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease. J Muscle Res Cell Motil. 2010;31:289-301 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
van Oort R, McCauley M, Dixit S, Pereira L, Yang Y, Respress J, et al. Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure. Circulation. 2010;122:2669-79 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:2000
  • 免疫印迹; 大鼠; 1:2000
Prasad A, Inesi G. Silencing calcineurin A subunit reduces SERCA2 expression in cardiac myocytes. Am J Physiol Heart Circ Physiol. 2011;300:H173-80 pubmed 出版商
  • 免疫印迹; 小鼠
Yang L, Kockskamper J, Khan S, Suarez J, Walther S, Doleschal B, et al. cAMP- and Ca²(+) /calmodulin-dependent protein kinases mediate inotropic, lusitropic and arrhythmogenic effects of urocortin 2 in mouse ventricular myocytes. Br J Pharmacol. 2011;162:544-56 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Alcalai R, Wakimoto H, Arad M, Planer D, Konno T, Wang L, et al. Prevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation. J Cardiovasc Electrophysiol. 2011;22:316-24 pubmed 出版商
  • 免疫印迹; 大鼠
Sun L, Ai J, Wang N, Zhang R, Li J, Zhang T, et al. Cerebral ischemia elicits aberration in myocardium contractile function and intracellular calcium handling. Cell Physiol Biochem. 2010;26:421-30 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Kalofoutis C, Mourouzis I, Galanopoulos G, Dimopoulos A, Perimenis P, Spanou D, et al. Thyroid hormone can favorably remodel the diabetic myocardium after acute myocardial infarction. Mol Cell Biochem. 2010;345:161-9 pubmed 出版商
  • 免疫印迹; 大鼠
Zeiger U, Mitchell C, Khurana T. Superior calcium homeostasis of extraocular muscles. Exp Eye Res. 2010;91:613-22 pubmed 出版商
  • 免疫印迹; 大鼠
Neviere R, Hassoun S, Decoster B, Bouazza Y, Montaigne D, Marechal X, et al. Caspase-dependent protein phosphatase 2A activation contributes to endotoxin-induced cardiomyocyte contractile dysfunction. Crit Care Med. 2010;38:2031-6 pubmed 出版商
  • 免疫印迹; domestic rabbit; 1:1000
Liu Y, Huang H, Xia W, Tang Y, Li H, Huang C. NADPH oxidase inhibition ameliorates cardiac dysfunction in rabbits with heart failure. Mol Cell Biochem. 2010;343:143-53 pubmed 出版商
  • 免疫组化; 人类; 1:50
Di Blasi C, Blasevich F, Bellafiore E, Mottarelli E, Gibertini S, Zanotti S, et al. Calsequestrin and junctin immunoreactivity in hexagonally cross-linked tubular arrays myopathy. Neuromuscul Disord. 2010;20:326-9 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000
Aguiar C, Andrade V, Gomes E, Alves M, Ladeira M, Pinheiro A, et al. Succinate modulates Ca(2+) transient and cardiomyocyte viability through PKA-dependent pathway. Cell Calcium. 2010;47:37-46 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Donoghue P, Hughes C, Vissers J, Langridge J, Dunn M. Nonionic detergent phase extraction for the proteomic analysis of heart membrane proteins using label-free LC-MS. Proteomics. 2008;8:3895-905 pubmed 出版商
  • 免疫印迹; 小鼠
Rizzi N, Liu N, Napolitano C, Nori A, Turcato F, Colombi B, et al. Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model. Circ Res. 2008;103:298-306 pubmed 出版商
  • 免疫印迹; 小鼠
Zhu M, Gach A, Liu G, Xu X, Lim C, Zhang J, et al. Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active G alpha o* protein. Am J Physiol Heart Circ Physiol. 2008;294:H1335-47 pubmed 出版商
  • 免疫印迹; 大鼠; 1:3,000
Birkeland J, Swift F, Tovsrud N, Enger U, Lunde P, Qvigstad E, et al. Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes. Am J Physiol Heart Circ Physiol. 2007;293:H2367-76 pubmed
  • 免疫印迹; 小鼠
Szczesna Cordary D, Jones M, Moore J, Watt J, Kerrick W, Xu Y, et al. Myosin regulatory light chain E22K mutation results in decreased cardiac intracellular calcium and force transients. FASEB J. 2007;21:3974-85 pubmed
  • 免疫印迹; 大鼠; 1:1,000
Pantos C, Mourouzis I, Markakis K, Dimopoulos A, Xinaris C, Kokkinos A, et al. Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats. Eur J Cardiothorac Surg. 2007;32:333-9 pubmed
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠; 1:2000
Stenoien D, Knyushko T, Londono M, Opresko L, Mayer M, Brady S, et al. Cellular trafficking of phospholamban and formation of functional sarcoplasmic reticulum during myocyte differentiation. Am J Physiol Cell Physiol. 2007;292:C2084-94 pubmed
  • 免疫印迹; 人类
Armoundas A, Rose J, Aggarwal R, Stuyvers B, O ROURKE B, Kass D, et al. Cellular and molecular determinants of altered Ca2+ handling in the failing rabbit heart: primary defects in SR Ca2+ uptake and release mechanisms. Am J Physiol Heart Circ Physiol. 2007;292:H1607-18 pubmed
  • 免疫印迹; 大鼠; 1:1,000
Rodriguez P, Mitton B, Waggoner J, Kranias E. Identification of a novel phosphorylation site in protein phosphatase inhibitor-1 as a negative regulator of cardiac function. J Biol Chem. 2006;281:38599-608 pubmed
  • 免疫印迹; 小鼠
Takahashi T, Tang T, Lai N, Roth D, Rebolledo B, Saito M, et al. Increased cardiac adenylyl cyclase expression is associated with increased survival after myocardial infarction. Circulation. 2006;114:388-96 pubmed
  • 免疫印迹; 人类; 1:500
  • 免疫印迹; pigs ; 1:500
Dolnikov K, Shilkrut M, Zeevi Levin N, Gerecht Nir S, Amit M, Danon A, et al. Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction. Stem Cells. 2006;24:236-45 pubmed
  • 免疫印迹; 大鼠; 1:2,000
Yamamura K, Steenbergen C, Murphy E. Protein kinase C and preconditioning: role of the sarcoplasmic reticulum. Am J Physiol Heart Circ Physiol. 2005;289:H2484-90 pubmed
  • 免疫印迹; 小鼠
Rothermel B, Berenji K, Tannous P, Kutschke W, Dey A, Nolan B, et al. Differential activation of stress-response signaling in load-induced cardiac hypertrophy and failure. Physiol Genomics. 2005;23:18-27 pubmed
  • 免疫印迹; 小鼠
Tavi P, Sjogren M, Lunde P, Zhang S, Abbate F, Vennstrom B, et al. Impaired Ca2+ handling and contraction in cardiomyocytes from mice with a dominant negative thyroid hormone receptor alpha1. J Mol Cell Cardiol. 2005;38:655-63 pubmed
  • 免疫印迹; 小鼠
Nakayama M, Yan X, Price R, Borg T, Ito K, Sanbe A, et al. Chronic ventricular myocyte-specific overexpression of angiotensin II type 2 receptor results in intrinsic myocyte contractile dysfunction. Am J Physiol Heart Circ Physiol. 2005;288:H317-27 pubmed
  • 免疫印迹; 大鼠; 1:1,000
Coutu P, Metzger J. Genetic manipulation of calcium-handling proteins in cardiac myocytes. I. Experimental studies. Am J Physiol Heart Circ Physiol. 2005;288:H601-12 pubmed
Liu T, Xiong F, Qi X, Xiao J, Villeneuve L, Abu Taha I, et al. Altered calcium handling produces reentry-promoting action potential alternans in atrial fibrillation-remodeled hearts. JCI Insight. 2020;5: pubmed 出版商
Hadipour Lakmehsari S, Driouchi A, Lee S, Kuzmanov U, Callaghan N, Heximer S, et al. Nanoscale reorganization of sarcoplasmic reticulum in pressure-overload cardiac hypertrophy visualized by dSTORM. Sci Rep. 2019;9:7867 pubmed 出版商
Miranda Silva D, Gonçalves Rodrigues P, Almeida Coelho J, Hamdani N, Lima T, Conceição G, et al. Characterization of biventricular alterations in myocardial (reverse) remodelling in aortic banding-induced chronic pressure overload. Sci Rep. 2019;9:2956 pubmed 出版商
Liu R, Miller C, D Annibale C, Vo K, Jacobs A. Differential localizations of protein phosphatase 1 isoforms determine their physiological function in the heart. Acta Biochim Biophys Sin (Shanghai). 2019;51:323-330 pubmed 出版商
Koyani C, Trummer C, Shrestha N, Scheruebel S, Bourgeois B, Plastira I, et al. Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes. Front Physiol. 2018;9:1622 pubmed 出版商
Makarewich C, Munir A, Schiattarella G, Bezprozvannaya S, Raguimova O, Cho E, et al. The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy. elife. 2018;7: pubmed 出版商
Ng K, Lau Y, Dhandhania V, Cai Z, Lee Y, Lai W, et al. Empagliflozin Ammeliorates High Glucose Induced-Cardiac Dysfuntion in Human iPSC-Derived Cardiomyocytes. Sci Rep. 2018;8:14872 pubmed 出版商
Kushnir A, Santulli G, Reiken S, Coromilas E, Godfrey S, Brunjes D, et al. Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure. Circulation. 2018;: pubmed 出版商
Lee S, Hadipour Lakmehsari S, Miyake T, Gramolini A. Three-dimensional imaging reveals endo(sarco)plasmic reticulum-containing invaginations within the nucleoplasm of muscle. Am J Physiol Cell Physiol. 2018;314:C257-C267 pubmed 出版商
Liu G, Zhu H, Cai W, Wang X, Jiang M, Essandoh K, et al. Regulation of BECN1-Mediated Autophagy by HSPB6: Insights from A Human HSPB6S10F Mutant. Autophagy. 2017;:1-56 pubmed 出版商
Jacobsen B, Leopoldo A, Cordeiro J, Campos D, Nascimento A, Sugizaki M, et al. Cardiac, Metabolic and Molecular Profiles of Sedentary Rats in the Initial Moment of Obesity. Arq Bras Cardiol. 2017;: pubmed 出版商
Sacchi V, Wang B, Kubli D, Martinez A, Jin J, Alvarez R, et al. Peptidyl-Prolyl Isomerase 1 Regulates Ca2+ Handling by Modulating Sarco(Endo)Plasmic Reticulum Calcium ATPase and Na2+/Ca2+ Exchanger 1 Protein Levels and Function. J Am Heart Assoc. 2017;6: pubmed 出版商
Patel B, Raad M, Sebag I, Chalifour L. Sex-specific cardiovascular responses to control or high fat diet feeding in C57bl/6 mice chronically exposed to bisphenol A. Toxicol Rep. 2015;2:1310-1318 pubmed 出版商
Li Y, Baldwin T, Wang Y, Subramaniam J, Carbajal A, Brand C, et al. Loss of type 9 adenylyl cyclase triggers reduced phosphorylation of Hsp20 and diastolic dysfunction. Sci Rep. 2017;7:5522 pubmed 出版商
Røe A, Aronsen J, Skårdal K, Hamdani N, Linke W, Danielsen H, et al. Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy. Cardiovasc Res. 2017;113:1161-1172 pubmed 出版商
Ravel Chapuis A, Belanger G, Cote J, Michel R, Jasmin B. Misregulation of calcium-handling proteins promotes hyperactivation of calcineurin-NFAT signaling in skeletal muscle of DM1 mice. Hum Mol Genet. 2017;26:2192-2206 pubmed 出版商
Barbagallo F, Xu B, Reddy G, West T, Wang Q, Fu Q, et al. Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure. Circ Res. 2016;119:931-43 pubmed 出版商
Manning J, Withers C, Levitan B, Smith J, Andres D, Satin J. Loss of Rad-GTPase produces a novel adaptive cardiac phenotype resistant to systolic decline with aging. Am J Physiol Heart Circ Physiol. 2015;309:H1336-45 pubmed 出版商
Lugenbiel P, Wenz F, Govorov K, Schweizer P, Katus H, Thomas D. Atrial fibrillation complicated by heart failure induces distinct remodeling of calcium cycling proteins. PLoS ONE. 2015;10:e0116395 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
Phospholamban Monoclonal Antibody (2D12)
目录# :
MA3-922
规格 :
100微克
价格 :
美国399.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Canine, Chicken, Guinea Pig, Human, Mouse, Ovine, Porcine, Rabbit, Rat
应用 :
Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:5,000
物种 :
Canine, Chicken, Guinea Pig, Human, Mouse, Ovine, Porcine, Rabbit, Rat
克隆 :
2D12
抗体亚型 :
IgG2a
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.
免疫原 :
Synthetic peptide corresponding to residues D(2) K V Q Y L T R S A I R R A S T I E M P Q Q A R(25) of canine Phospholamban.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:5,000
别名 :
cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国