产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
RyR1单克隆抗体(34C)
目录 :
MA3-925
规格 :
100微升
价格 :
美国399.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
34C
反应物种 :
人类, 小鼠, 大鼠, , , , pigs , 斑马鱼, 家羊, 非洲爪蛙, domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, proximity ligation assay, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 185
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:2000; 图 2a
Dai W, Laforest B, Tyan L, Shen K, Nadadur R, Alvarado F, et al. A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Eshima H, Tamura Y, Kakehi S, Kurebayashi N, Murayama T, Nakamura K, et al. Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle. Physiol Rep. 2017;5: pubmed 出版商
  • 免疫组化; 小鼠; 1:300; 图 3c
  • 免疫印迹; 小鼠; 1:2000; 图 s2f
Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 1b
Amici D, Pinal Fernández I, Mázala D, Lloyd T, Corse A, Christopher Stine L, et al. Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis. Acta Neuropathol Commun. 2017;5:24 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2d
Fajardo V, Gamu D, Mitchell A, Bloemberg D, Bombardier E, Chambers P, et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE. 2017;12:e0173708 pubmed 出版商
  • 免疫印迹; 大鼠; 图 2e
Himori K, Abe M, Tatebayashi D, Lee J, Westerblad H, Lanner J, et al. Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension. PLoS ONE. 2017;12:e0169146 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2500; 图 4a
Kanzaki K, Watanabe D, Kuratani M, Yamada T, Matsunaga S, Wada M. Role of calpain in eccentric contraction-induced proteolysis of Ca2+-regulatory proteins and force depression in rat fast-twitch skeletal muscle. J Appl Physiol (1985). 2017;122:396-405 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Huang M, Lee K, Kim K, Ahn M, Cho C, Kim D, et al. The maintenance ability and Ca2+ availability of skeletal muscle are enhanced by sildenafil. Exp Mol Med. 2016;48:e278 pubmed 出版商
  • 免疫印迹; 人类; 图 8a
Søndergaard M, Liu Y, Larsen K, Nani A, Tian X, Holt C, et al. The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. J Biol Chem. 2017;292:1385-1395 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Robison P, Sussan T, Chen H, Biswal S, Schneider M, Hernández Ochoa E. Impaired calcium signaling in muscle fibers from intercostal and foot skeletal muscle in a cigarette smoke-induced mouse model of COPD. Muscle Nerve. 2017;56:282-291 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Sun B, Guo W, Tian X, Yao J, Zhang L, Wang R, et al. The Cytoplasmic Region of Inner Helix S6 Is an Important Determinant of Cardiac Ryanodine Receptor Channel Gating. J Biol Chem. 2016;291:26024-26034 pubmed
  • 免疫印迹; 小鼠; 1:1000; 图 s2
Xiao Z, Guo W, Sun B, Hunt D, Wei J, Liu Y, et al. Enhanced Cytosolic Ca2+ Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias. J Biol Chem. 2016;291:24528-24537 pubmed
  • 免疫组化; 小鼠; 1:500; 图 1a
  • 免疫印迹; 小鼠; 1:1000
Oláh T, Bodnár D, Tóth A, Vincze J, Fodor J, Reischl B, et al. Cannabinoid signalling inhibits sarcoplasmic Ca2+ release and regulates excitation-contraction coupling in mammalian skeletal muscle. J Physiol. 2016;594:7381-7398 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 2c
Yang S, Ben Shalom R, Ahn M, Liptak A, van Rijn R, Whistler J, et al. ?-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment. Cell Rep. 2016;16:1518-1526 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2e
Lopez R, Byrne S, Vukcevic M, Sekulic Jablanovic M, Xu L, Brink M, et al. An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities. Sci Signal. 2016;9:ra68 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 1
Salazar Cantú A, Pérez Treviño P, Montalvo Parra D, Balderas Villalobos J, Gómez Víquez N, García N, et al. Role of SERCA and the sarcoplasmic reticulum calcium content on calcium waves propagation in rat ventricular myocytes. Arch Biochem Biophys. 2016;604:11-9 pubmed 出版商
  • proximity ligation assay; 小鼠; 1:500; 图 4
Hall A, Burke N, Dongworth R, Kalkhoran S, Dyson A, Vicencio J, et al. Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction. Cell Death Dis. 2016;7:e2238 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 2
Mosca B, Eckhardt J, Bergamelli L, Treves S, Bongianino R, De Negri M, et al. Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles. J Biol Chem. 2016;291:14555-65 pubmed 出版商
  • 免疫细胞化学; pigs ; 1:200; 图 6
Dries E, Santiago D, Johnson D, Gilbert G, Holemans P, Korte S, et al. Calcium/calmodulin-dependent kinase II and nitric oxide synthase 1-dependent modulation of ryanodine receptors during ?-adrenergic stimulation is restricted to the dyadic cleft. J Physiol. 2016;594:5923-5939 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
  • 免疫印迹; 人类; 图 1
Sekulic Jablanovic M, Ullrich N, Goldblum D, Palmowski Wolfe A, Zorzato F, Treves S. Functional characterization of orbicularis oculi and extraocular muscles. J Gen Physiol. 2016;147:395-406 pubmed 出版商
  • 免疫印迹; 人类; 图 2
  • 免疫印迹; 小鼠; 图 1
Toral Ojeda I, Aldanondo G, Lasa Elgarresta J, Lasa Fernández H, Fernandez Torron R, Lopez de Munain A, et al. Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle. Expert Rev Mol Med. 2016;18:e7 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Asensio López M, Soler F, Sánchez Más J, Pascual Figal D, Fernández Belda F, Lax A. Early oxidative damage induced by doxorubicin: Source of production, protection by GKT137831 and effect on Ca(2+) transporters in HL-1 cardiomyocytes. Arch Biochem Biophys. 2016;594:26-36 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Rani S, Park C, Sreenivasaiah P, Kim D. Characterization of Ca(2+)-Dependent Protein-Protein Interactions within the Ca(2+) Release Units of Cardiac Sarcoplasmic Reticulum. Mol Cells. 2016;39:149-55 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 6
Brody M, Feng L, Grimes A, Hacker T, Olson T, Kamp T, et al. LRRC10 is required to maintain cardiac function in response to pressure overload. Am J Physiol Heart Circ Physiol. 2016;310:H269-78 pubmed 出版商
  • 免疫组化-冰冻切片; 斑马鱼; 图 5
Furlan S, Mosole S, Murgia M, Nagaraj N, Argenton F, Volpe P, et al. Calsequestrins in skeletal and cardiac muscle from adult Danio rerio. J Muscle Res Cell Motil. 2016;37:27-39 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2500
Sharma P, Abbasi C, Lazic S, Teng A, Wang D, Dubois N, et al. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun. 2015;6:8391 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Fajardo V, Bombardier E, McMillan E, TRAN K, Wadsworth B, Gamu D, et al. Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype. Dis Model Mech. 2015;8:999-1009 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Rokach O, Sekulic Jablanovic M, Voermans N, Wilmshurst J, Pillay K, Heytens L, et al. Epigenetic changes as a common trigger of muscle weakness in congenital myopathies. Hum Mol Genet. 2015;24:4636-47 pubmed 出版商
  • 免疫印迹; 人类
Kraeva N, Heytens L, Jungbluth H, Treves S, Voermans N, Kamsteeg E, et al. Compound RYR1 heterozygosity resulting in a complex phenotype of malignant hyperthermia susceptibility and a core myopathy. Neuromuscul Disord. 2015;25:567-76 pubmed 出版商
  • 免疫印迹; 小鼠
Van B, Nishi M, Komazaki S, Ichimura A, Kakizawa S, Nakanaga K, et al. Mitsugumin 56 (hedgehog acyltransferase-like) is a sarcoplasmic reticulum-resident protein essential for postnatal muscle maturation. FEBS Lett. 2015;589:1095-104 pubmed 出版商
  • 免疫组化; 小鼠; 1 ug/ml
Rossi D, Vezzani B, Galli L, Paolini C, Toniolo L, Pierantozzi E, et al. A mutation in the CASQ1 gene causes a vacuolar myopathy with accumulation of sarcoplasmic reticulum protein aggregates. Hum Mutat. 2014;35:1163-70 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 1
Mandikian D, Bocksteins E, Parajuli L, Bishop H, Cerda O, Shigemoto R, et al. Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K+ channels and ryanodine receptors. J Comp Neurol. 2014;522:3555-74 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Li B, Jie W, Huang L, Wei P, Li S, Luo Z, et al. Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling. Nat Neurosci. 2014;17:1055-63 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Shilling D, Müller M, Takano H, Mak D, Abel T, Coulter D, et al. Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis. J Neurosci. 2014;34:6910-23 pubmed 出版商
  • 免疫沉淀; 人类; 1:1000
  • 免疫印迹; 人类; 1:1000
Vervliet T, Decrock E, Molgo J, Sorrentino V, Missiaen L, Leybaert L, et al. Bcl-2 binds to and inhibits ryanodine receptors. J Cell Sci. 2014;127:2782-92 pubmed 出版商
  • 免疫组化-自由浮动切片; 大鼠; 1 ug/ml
King A, Manning C, Trimmer J. A unique ion channel clustering domain on the axon initial segment of mammalian neurons. J Comp Neurol. 2014;522:2594-608 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:500; 图 s1b
Liu J, Supnet C, Sun S, Zhang H, Good L, Popugaeva E, et al. The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease. Channels (Austin). 2014;8:230-42 pubmed
  • 免疫印迹; 小鼠; 1:1000
Chen W, Wang R, Chen B, Zhong X, Kong H, Bai Y, et al. The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias. Nat Med. 2014;20:184-92 pubmed 出版商
  • 免疫细胞化学; 小鼠
Lalioti V, Ilari A, O Connell D, Poser E, Sandoval I, Colotti G. Sorcin links calcium signaling to vesicle trafficking, regulates Polo-like kinase 1 and is necessary for mitosis. PLoS ONE. 2014;9:e85438 pubmed 出版商
  • 免疫细胞化学; 大鼠
Rossi D, Bencini C, Maritati M, Benini F, Lorenzini S, Pierantozzi E, et al. Distinct regions of triadin are required for targeting and retention at the junctional domain of the sarcoplasmic reticulum. Biochem J. 2014;458:407-17 pubmed 出版商
  • 免疫细胞化学; pigs ; 1:200
Haq K, Daniels R, Miller L, Miura M, ter Keurs H, Bungay S, et al. Evoked centripetal Ca(2+) mobilization in cardiac Purkinje cells: insight from a model of three Ca(2+) release regions. J Physiol. 2013;591:4301-19 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Attali R, Aharoni S, Treves S, Rokach O, Becker Cohen M, Fellig Y, et al. Variable myopathic presentation in a single family with novel skeletal RYR1 mutation. PLoS ONE. 2013;8:e69296 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000
Eshima H, Tanaka Y, Sonobe T, Inagaki T, Nakajima T, Poole D, et al. In vivo imaging of intracellular Ca2+ after muscle contractions and direct Ca2+ injection in rat skeletal muscle in diabetes. Am J Physiol Regul Integr Comp Physiol. 2013;305:R610-8 pubmed 出版商
  • 免疫组化; 小鼠
Caruso N, Herberth B, Bartoli M, Puppo F, Dumonceaux J, Zimmermann A, et al. Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy. PLoS Genet. 2013;9:e1003550 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Kraeva N, Zvaritch E, Rossi A, Goonasekera S, Zaid H, Frodis W, et al. Novel excitation-contraction uncoupled RYR1 mutations in patients with central core disease. Neuromuscul Disord. 2013;23:120-32 pubmed 出版商
  • 免疫印迹; domestic rabbit
Popova O, Baker M, Tran T, Le T, Serysheva I. Identification of ATP-binding regions in the RyR1 Ca²? release channel. PLoS ONE. 2012;7:e48725 pubmed 出版商
  • 免疫印迹; 人类
Middlekauff H, Vigna C, Verity M, Fonarow G, Horwich T, Hamilton M, et al. Abnormalities of calcium handling proteins in skeletal muscle mirror those of the heart in humans with heart failure: a shared mechanism?. J Card Fail. 2012;18:724-33 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Hernandez A, Schiffer T, Ivarsson N, Cheng A, Bruton J, Lundberg J, et al. Dietary nitrate increases tetanic [Ca2+]i and contractile force in mouse fast-twitch muscle. J Physiol. 2012;590:3575-83 pubmed 出版商
  • 免疫印迹; 大鼠
Sliwinska J, Dudka J, Korga A, Burdan F, Matysiak W, Jodlowska Jedrych B, et al. Tirapazamine-doxorubicin interaction referring to heart oxidative stress and Ca²? balance protein levels. Oxid Med Cell Longev. 2012;2012:890826 pubmed 出版商
  • 免疫印迹; 大鼠
Korga A, Dudka J, Burdan F, Sliwinska J, Mandziuk S, Dawidek Pietryka K. The redox imbalance and the reduction of contractile protein content in rat hearts administered with L-thyroxine and Doxorubicin. Oxid Med Cell Longev. 2012;2012:681367 pubmed 出版商
  • 免疫组化; 非洲爪蛙; 1:200
  • 免疫印迹; 非洲爪蛙; 1:800
Perin P, Botta L, Tritto S, Laforenza U. Expression and localization of ryanodine receptors in the frog semicircular canal. J Biomed Biotechnol. 2012;2012:398398 pubmed 出版商
  • 免疫印迹; 小鼠
Goonasekera S, Hammer K, Auger Messier M, Bodi I, Chen X, Zhang H, et al. Decreased cardiac L-type Ca²? channel activity induces hypertrophy and heart failure in mice. J Clin Invest. 2012;122:280-90 pubmed 出版商
  • 免疫印迹; 小鼠; 1:400
Ackermann M, Ziman A, Strong J, Zhang Y, Hartford A, Ward C, et al. Integrity of the network sarcoplasmic reticulum in skeletal muscle requires small ankyrin 1. J Cell Sci. 2011;124:3619-30 pubmed 出版商
  • 免疫组化; 人类; 1:200
Roche J, Ru L, O Neill A, Resneck W, Lovering R, Bloch R. Unmasking potential intracellular roles for dysferlin through improved immunolabeling methods. J Histochem Cytochem. 2011;59:964-75 pubmed 出版商
  • 免疫组化; domestic rabbit
Sacchetto R, Sharova E, Patruno M, Maccatrozzo L, Damiani E, Mascarello F. Overexpression of histidine-rich calcium binding protein in equine ventricular myocardium. Vet J. 2012;193:157-61 pubmed 出版商
  • 免疫印迹; 小鼠
Treves S, Thurnheer R, Mosca B, Vukcevic M, Bergamelli L, Voltan R, et al. SRP-35, a newly identified protein of the skeletal muscle sarcoplasmic reticulum, is a retinol dehydrogenase. Biochem J. 2012;441:731-41 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Jung C, Fuhrmann M, Honarnejad K, Van Leuven F, Herms J. Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo. J Neurochem. 2011;119:1064-73 pubmed 出版商
  • 免疫细胞化学; 小鼠
Wu C, Jia Z, Wang W, Ballou L, Jiang Y, Chen B, et al. PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes. PLoS ONE. 2011;6:e24404 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Andersson D, Betzenhauser M, Reiken S, Meli A, Umanskaya A, Xie W, et al. Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging. Cell Metab. 2011;14:196-207 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Li D, Shin J, Duan D. iNOS ablation does not improve specific force of the extensor digitorum longus muscle in dystrophin-deficient mdx4cv mice. PLoS ONE. 2011;6:e21618 pubmed 出版商
  • 免疫印迹; 人类; 1:2500
Oláh T, Fodor J, Ruzsnavszky O, Vincze J, Berbey C, Allard B, et al. Overexpression of transient receptor potential canonical type 1 (TRPC1) alters both store operated calcium entry and depolarization-evoked calcium signals in C2C12 cells. Cell Calcium. 2011;49:415-25 pubmed 出版商
  • 免疫印迹; 小鼠
Ryan T, Sharma P, Ignatchenko A, MacLennan D, Kislinger T, Gramolini A. Identification of novel ryanodine receptor 1 (RyR1) protein interaction with calcium homeostasis endoplasmic reticulum protein (CHERP). J Biol Chem. 2011;286:17060-8 pubmed 出版商
  • 免疫印迹; 小鼠
Mital R, Zhang W, Cai M, Huttinger Z, Goodman L, Wheeler D, et al. Antioxidant network expression abrogates oxidative posttranslational modifications in mice. Am J Physiol Heart Circ Physiol. 2011;300:H1960-70 pubmed 出版商
  • 免疫组化; 小鼠; 1:500
  • 免疫印迹; 小鼠; 1:5000
Ojima K, Ono Y, Ottenheijm C, Hata S, Suzuki H, Granzier H, et al. Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles. J Mol Biol. 2011;407:439-49 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
  • 免疫印迹; 人类; 图 1
Ullrich N, Fischer D, Kornblum C, Walter M, Niggli E, Zorzato F, et al. Alterations of excitation-contraction coupling and excitation coupled Ca(2+) entry in human myotubes carrying CAV3 mutations linked to rippling muscle. Hum Mutat. 2011;32:309-17 pubmed 出版商
  • 免疫沉淀; 小鼠
  • 免疫印迹; 小鼠
Wang R, Zhong X, Meng X, Koop A, Tian X, Jones P, et al. Localization of the dantrolene-binding sequence near the FK506-binding protein-binding site in the three-dimensional structure of the ryanodine receptor. J Biol Chem. 2011;286:12202-12 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Horiuchi Hirose M, Kashihara T, Nakada T, Kurebayashi N, Shimojo H, Shibazaki T, et al. Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes. Am J Physiol Heart Circ Physiol. 2011;300:H978-88 pubmed 出版商
  • 免疫印迹; 小鼠
Lu Y, Chen Y, Kao Y, Wu T, Chen S, Chen Y. Extracellular matrix of collagen modulates intracellular calcium handling and electrophysiological characteristics of HL-1 cardiomyocytes with activation of angiotensin II type 1 receptor. J Card Fail. 2011;17:82-90 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Li D, Yue Y, Lai Y, Hakim C, Duan D. Nitrosative stress elicited by nNOSµ delocalization inhibits muscle force in dystrophin-null mice. J Pathol. 2011;223:88-98 pubmed 出版商
  • 免疫细胞化学; 人类
Treves S, Vukcevic M, Jeannet P, Levano S, Girard T, Urwyler A, et al. Enhanced excitation-coupled Ca(2+) entry induces nuclear translocation of NFAT and contributes to IL-6 release from myotubes from patients with central core disease. Hum Mol Genet. 2011;20:589-600 pubmed 出版商
  • 免疫印迹; domestic rabbit
Suenari K, Chen Y, Kao Y, Cheng C, Lin Y, Chen Y, et al. Discrepant electrophysiological characteristics and calcium homeostasis of left atrial anterior and posterior myocytes. Basic Res Cardiol. 2011;106:65-74 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000
Russ D, Grandy J, Toma K, Ward C. Ageing, but not yet senescent, rats exhibit reduced muscle quality and sarcoplasmic reticulum function. Acta Physiol (Oxf). 2011;201:391-403 pubmed 出版商
  • 免疫印迹; 小鼠
Zhao X, Yamazaki D, Park K, Komazaki S, Tjondrokoesoemo A, Nishi M, et al. Ca2+ overload and sarcoplasmic reticulum instability in tric-a null skeletal muscle. J Biol Chem. 2010;285:37370-6 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Zhang K, Heidrich F, Degray B, Boehmerle W, Ehrlich B. Paclitaxel accelerates spontaneous calcium oscillations in cardiomyocytes by interacting with NCS-1 and the InsP3R. J Mol Cell Cardiol. 2010;49:829-35 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Bueno C, Ferreira J, Pereira M, Bacurau A, Brum P. Aerobic exercise training improves skeletal muscle function and Ca2+ handling-related protein expression in sympathetic hyperactivity-induced heart failure. J Appl Physiol (1985). 2010;109:702-9 pubmed 出版商
  • 免疫印迹; 小鼠
Zhang H, Sun S, Herreman A, De Strooper B, Bezprozvanny I. Role of presenilins in neuronal calcium homeostasis. J Neurosci. 2010;30:8566-80 pubmed 出版商
  • 免疫沉淀; 小鼠
Peng H, Yaney G, Kirber M. Modulation of Ca(2+) release through ryanodine receptors in vascular smooth muscle by protein kinase Calpha. Pflugers Arch. 2010;460:791-802 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Ferreira J, Bacurau A, Bueno C, Cunha T, Tanaka L, Jardim M, et al. Aerobic exercise training improves Ca2+ handling and redox status of skeletal muscle in mice. Exp Biol Med (Maywood). 2010;235:497-505 pubmed 出版商
  • 免疫印迹; 小鼠
Lee S, Grafweg S, Schneider T, Jimenez M, Giacobino J, Ghanem A, et al. Total beta-adrenoceptor deficiency results in cardiac hypotrophy and negative inotropy. Physiol Res. 2010;59:679-89 pubmed
  • 免疫组化; 人类; 1:250
Di Blasi C, Blasevich F, Bellafiore E, Mottarelli E, Gibertini S, Zanotti S, et al. Calsequestrin and junctin immunoreactivity in hexagonally cross-linked tubular arrays myopathy. Neuromuscul Disord. 2010;20:326-9 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000
Thomas M, Vigna C, Betik A, Tupling A, Hepple R. Initiating treadmill training in late middle age offers modest adaptations in Ca2+ handling but enhances oxidative damage in senescent rat skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2010;298:R1269-78 pubmed 出版商
  • 免疫沉淀; 大鼠
  • 免疫印迹; 大鼠; 1:3330
Tang W, Kravtsov G, Sauert M, Tong X, Hou X, Wong T, et al. Polyol pathway impairs the function of SERCA and RyR in ischemic-reperfused rat hearts by increasing oxidative modifications of these proteins. J Mol Cell Cardiol. 2010;49:58-69 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:20
Salnikov V, Lukyanenko Y, Lederer W, Lukyanenko V. Distribution of ryanodine receptors in rat ventricular myocytes. J Muscle Res Cell Motil. 2009;30:161-70 pubmed 出版商
  • 免疫印迹; 人类
Nef H, Mollmann H, Troidl C, Kostin S, Voss S, Hilpert P, et al. Abnormalities in intracellular Ca2+ regulation contribute to the pathomechanism of Tako-Tsubo cardiomyopathy. Eur Heart J. 2009;30:2155-64 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100
  • 免疫印迹; 小鼠; 1:100
Medina Ortiz W, Gregg E, Brun Zinkernagel A, Koulen P. Identification and functional distribution of intracellular ca channels in mouse lacrimal gland acinar cells. Open Ophthalmol J. 2007;1:8-16 pubmed 出版商
  • 免疫细胞化学; pigs ; 1:500
Patel J, Witkovsky P, Avshalumov M, Rice M. Mobilization of calcium from intracellular stores facilitates somatodendritic dopamine release. J Neurosci. 2009;29:6568-79 pubmed 出版商
  • 免疫印迹; 大鼠
O CONNELL K, Gannon J, Doran P, Ohlendieck K. Reduced expression of sarcalumenin and related Ca2+ -regulatory proteins in aged rat skeletal muscle. Exp Gerontol. 2008;43:958-61 pubmed 出版商
  • 免疫沉淀; 大鼠
  • 免疫印迹; 大鼠
Huke S, Bers D. Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes. Biochem Biophys Res Commun. 2008;376:80-5 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:800
  • 免疫细胞化学; 小鼠; 1:800
Witkovsky P, G briel R, Krizaj D. Anatomical and neurochemical characterization of dopaminergic interplexiform processes in mouse and rat retinas. J Comp Neurol. 2008;510:158-74 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:1000
  • 免疫印迹; 大鼠; 1:2500
Fu M, Li R, Fan L, He G, Thornburg K, Wang Z. Sarcoplasmic reticulum Ca2+ release channel ryanodine receptor (RyR2) plays a crucial role in aconitine-induced arrhythmias. Biochem Pharmacol. 2008;75:2147-56 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Liu J, Fu J, Siu C, Li R. Functional sarcoplasmic reticulum for calcium handling of human embryonic stem cell-derived cardiomyocytes: insights for driven maturation. Stem Cells. 2007;25:3038-44 pubmed
  • 免疫印迹; 大鼠; 1:2500
Fu M, Wu M, Wang J, Qiao Y, Wang Z. Disruption of the intracellular Ca2+ homeostasis in the cardiac excitation-contraction coupling is a crucial mechanism of arrhythmic toxicity in aconitine-induced cardiomyocytes. Biochem Biophys Res Commun. 2007;354:929-36 pubmed
  • 免疫沉淀; domestic rabbit; 图 5
  • 免疫印迹; domestic rabbit; 图 5
Völkers M, Loughrey C, Macquaide N, Remppis A, DeGeorge B, Wegner F, et al. S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes. Cell Calcium. 2007;41:135-43 pubmed
  • 免疫印迹; 小鼠
Moriguchi S, Nishi M, Komazaki S, Sakagami H, Miyazaki T, Masumiya H, et al. Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins. Proc Natl Acad Sci U S A. 2006;103:10811-6 pubmed
  • 免疫印迹; 小鼠
Antoons G, Vangheluwe P, Volders P, Bito V, Holemans P, Ceci M, et al. Increased phospholamban phosphorylation limits the force-frequency response in the MLP-/- mouse with heart failure. J Mol Cell Cardiol. 2006;40:350-60 pubmed
  • 免疫沉淀; domestic rabbit; 8 ug/time
Kohlhaas M, Zhang T, Seidler T, Zibrova D, Dybkova N, Steen A, et al. Increased sarcoplasmic reticulum calcium leak but unaltered contractility by acute CaMKII overexpression in isolated rabbit cardiac myocytes. Circ Res. 2006;98:235-44 pubmed
  • 免疫印迹; 大鼠
Mulvey C, Harno E, Keenan A, Ohlendieck K. Expression of the skeletal muscle dystrophin-dystroglycan complex and syntrophin-nitric oxide synthase complex is severely affected in the type 2 diabetic Goto-Kakizaki rat. Eur J Cell Biol. 2005;84:867-83 pubmed
  • 免疫印迹; 人类; 1:200
Marius P, Guerra M, Nathanson M, Ehrlich B, Leite M. Calcium release from ryanodine receptors in the nucleoplasmic reticulum. Cell Calcium. 2006;39:65-73 pubmed
  • 免疫印迹; 牛
Ethier M, Madison J. IL-4 inhibits calcium transients in bovine trachealis cells by a ryanodine receptor-dependent mechanism. FASEB J. 2006;20:154-6 pubmed
  • 免疫沉淀; domestic rabbit; 1:100
Kettlewell S, Most P, Currie S, Koch W, Smith G. S100A1 increases the gain of excitation-contraction coupling in isolated rabbit ventricular cardiomyocytes. J Mol Cell Cardiol. 2005;39:900-10 pubmed
  • 免疫印迹; 大鼠; 1:3,330
Liu J, Kam K, Borchert G, Kravtsov G, Ballard H, Wong T. Further study on the role of HSP70 on Ca2+ homeostasis in rat ventricular myocytes subjected to simulated ischemia. Am J Physiol Cell Physiol. 2006;290:C583-91 pubmed
  • 免疫组化; 人类
Chevessier F, Bauché Godard S, Leroy J, Koenig J, Paturneau Jouas M, Eymard B, et al. The origin of tubular aggregates in human myopathies. J Pathol. 2005;207:313-23 pubmed
  • 免疫组化; 小鼠; 1:100
Mori F, Okada M, Tomiyama M, Kaneko S, Wakabayashi K. Effects of ryanodine receptor activation on neurotransmitter release and neuronal cell death following kainic acid-induced status epilepticus. Epilepsy Res. 2005;65:59-70 pubmed
  • 免疫细胞化学; 犬; 1:500
Stuyvers B, Dun W, Matkovich S, Sorrentino V, Boyden P, ter Keurs H. Ca2+ sparks and waves in canine purkinje cells: a triple layered system of Ca2+ activation. Circ Res. 2005;97:35-43 pubmed
  • 免疫组化; 小鼠; 1:100
Ueda H, Oikawa A, Nakamura A, Terasawa F, Kawagishi K, Moriizumi T. Neuregulin receptor ErbB2 localization at T-tubule in cardiac and skeletal muscle. J Histochem Cytochem. 2005;53:87-91 pubmed
Furlan S, Campione M, Murgia M, Mosole S, Argenton F, Volpe P, et al. Calsequestrins New Calcium Store Markers of Adult Zebrafish Cerebellum and Optic Tectum. Front Neuroanat. 2020;14:15 pubmed 出版商
Braun J, Hamstra S, Messner H, Fajardo V. SERCA2a tyrosine nitration coincides with impairments in maximal SERCA activity in left ventricles from tafazzin-deficient mice. Physiol Rep. 2019;7:e14215 pubmed 出版商
Alvarado F, Bos J, Yuchi Z, Valdivia C, Hernández J, Zhao Y, et al. Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2. JCI Insight. 2019;5: pubmed 出版商
Puhl S, Weeks K, Güran A, Ranieri A, Boknik P, Kirchhefer U, et al. Role of type 2A phosphatase regulatory subunit B56α in regulating cardiac responses to β-adrenergic stimulation in vivo. Cardiovasc Res. 2019;115:519-529 pubmed 出版商
Yamada T, Himori K, Tatebayashi D, Yamada R, Ashida Y, Imai T, et al. Electrical Stimulation Prevents Preferential Skeletal Muscle Myosin Loss in Steroid-Denervation Rats. Front Physiol. 2018;9:1111 pubmed 出版商
Kirmiz M, Palacio S, Thapa P, King A, Sack J, Trimmer J. Remodeling neuronal ER-PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels. Mol Biol Cell. 2018;29:2410-2432 pubmed 出版商
Suman M, Sharpe J, Bentham R, Kotiadis V, Menegollo M, Pignataro V, et al. Inositol trisphosphate receptor-mediated Ca2+ signalling stimulates mitochondrial function and gene expression in core myopathy patients. Hum Mol Genet. 2018;27:2367-2382 pubmed 出版商
Wilder C, Pavlaki N, Dursun T, Gyimah P, Caldwell Dunn E, Ranieri A, et al. Facilitation of ischaemia-induced ventricular fibrillation by catecholamines is mediated by β1 and β2 agonism in the rat heart in vitro. Br J Pharmacol. 2018;175:1669-1690 pubmed 出版商
Laine J, Skoglund G, Fournier E, Tabti N. Development of the excitation-contraction coupling machinery and its relation to myofibrillogenesis in human iPSC-derived skeletal myocytes. Skelet Muscle. 2018;8:1 pubmed 出版商
Chen X, Weber C, Farrell E, Alvarado F, Zhao Y, Gomez A, et al. Sorcin ablation plus β-adrenergic stimulation generate an arrhythmogenic substrate in mouse ventricular myocytes. J Mol Cell Cardiol. 2018;114:199-210 pubmed 出版商
Irie T, Trussell L. Double-Nanodomain Coupling of Calcium Channels, Ryanodine Receptors, and BK Channels Controls the Generation of Burst Firing. Neuron. 2017;96:856-870.e4 pubmed 出版商
Liu Y, Wei J, Wong King Yuen S, Sun B, Tang Y, Wang R, et al. CPVT-associated cardiac ryanodine receptor mutation G357S with reduced penetrance impairs Ca2+ release termination and diminishes protein expression. PLoS ONE. 2017;12:e0184177 pubmed 出版商
Hu L, Ackermann M, Hecker P, Prosser B, King B, O Connell K, et al. Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin. Sci Adv. 2017;3:e1603081 pubmed 出版商
Kesireddy V. Evaluation of adipose-derived stem cells for tissue-engineered muscle repair construct-mediated repair of a murine model of volumetric muscle loss injury. Int J Nanomedicine. 2016;11:1461-73 pubmed 出版商
Desmond P, Muriel J, Markwardt M, Rizzo M, Bloch R. Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle. J Biol Chem. 2015;290:27854-67 pubmed 出版商
Olsson K, Cheng A, Alam S, Al Ameri M, Rullman E, Westerblad H, et al. Intracellular Ca(2+)-handling differs markedly between intact human muscle fibers and myotubes. Skelet Muscle. 2015;5:26 pubmed 出版商
Georgiou D, Dagnino Acosta A, Lee C, Griffin D, Wang H, Lagor W, et al. Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism. J Biol Chem. 2015;290:23751-65 pubmed 出版商
Yamada T, Abe M, Lee J, Tatebayashi D, Himori K, Kanzaki K, et al. Muscle dysfunction associated with adjuvant-induced arthritis is prevented by antioxidant treatment. Skelet Muscle. 2015;5:20 pubmed 出版商
Chang Liao M, De Boer T, Mutoh H, Raad N, Richter C, Wagner E, et al. Sensing Cardiac Electrical Activity With a Cardiac Myocyte--Targeted Optogenetic Voltage Indicator. Circ Res. 2015;117:401-12 pubmed 出版商
Lee C, Dagnino Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, et al. Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function. Skelet Muscle. 2015;5:4 pubmed 出版商
Fero K, Bergeron S, Horstick E, Codore H, Li G, Ono F, et al. Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure. Dis Model Mech. 2014;7:289-98 pubmed 出版商
Rokach O, Ullrich N, Rausch M, Mouly V, Zhou H, Muntoni F, et al. Establishment of a human skeletal muscle-derived cell line: biochemical, cellular and electrophysiological characterization. Biochem J. 2013;455:169-77 pubmed 出版商
Boncompagni S, Thomas M, Lopez J, Allen P, Yuan Q, Kranias E, et al. Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis. PLoS ONE. 2012;7:e39962 pubmed 出版商
Biesmans L, Macquaide N, Heinzel F, Bito V, Smith G, Sipido K. Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density. PLoS ONE. 2011;6:e25100 pubmed 出版商
Kushnir A, Shan J, Betzenhauser M, Reiken S, Marks A. Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure. Proc Natl Acad Sci U S A. 2010;107:10274-9 pubmed 出版商
Uchinoumi H, Yano M, Suetomi T, Ono M, Xu X, Tateishi H, et al. Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor. Circ Res. 2010;106:1413-24 pubmed 出版商
Chen X, Tang T, Tu H, Nelson O, Pook M, Hammer R, et al. Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3. J Neurosci. 2008;28:12713-24 pubmed 出版商
Domeier T, Zima A, Maxwell J, Huke S, Mignery G, Blatter L. IP3 receptor-dependent Ca2+ release modulates excitation-contraction coupling in rabbit ventricular myocytes. Am J Physiol Heart Circ Physiol. 2008;294:H596-604 pubmed 出版商
Hertle D, Yeckel M. Distribution of inositol-1,4,5-trisphosphate receptor isotypes and ryanodine receptor isotypes during maturation of the rat hippocampus. Neuroscience. 2007;150:625-38 pubmed
Welshhans K, Rehder V. Nitric oxide regulates growth cone filopodial dynamics via ryanodine receptor-mediated calcium release. Eur J Neurosci. 2007;26:1537-47 pubmed
Rogers R, Van Meter M, Hermann G. Tumor necrosis factor potentiates central vagal afferent signaling by modulating ryanodine channels. J Neurosci. 2006;26:12642-6 pubmed
Guo T, Zhang T, Mestril R, Bers D. Ca2+/Calmodulin-dependent protein kinase II phosphorylation of ryanodine receptor does affect calcium sparks in mouse ventricular myocytes. Circ Res. 2006;99:398-406 pubmed
Lunde P, Sejersted O, Thorud H, Tønnessen T, Henriksen U, Christensen G, et al. Effects of congestive heart failure on Ca2+ handling in skeletal muscle during fatigue. Circ Res. 2006;98:1514-9 pubmed
Anyatonwu G, Ehrlich B. Organic cation permeation through the channel formed by polycystin-2. J Biol Chem. 2005;280:29488-93 pubmed
Bare D, Kettlun C, Liang M, Bers D, Mignery G. Cardiac type 2 inositol 1,4,5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II. J Biol Chem. 2005;280:15912-20 pubmed
Brini M, Manni S, Pierobon N, Du G, Sharma P, MacLennan D, et al. Ca2+ signaling in HEK-293 and skeletal muscle cells expressing recombinant ryanodine receptors harboring malignant hyperthermia and central core disease mutations. J Biol Chem. 2005;280:15380-9 pubmed
Takaseya T, Ishimatsu M, Tayama E, Nishi A, Akasu T, Aoyagi S. Mechanical unloading improves intracellular Ca2+ regulation in rats with doxorubicin-induced cardiomyopathy. J Am Coll Cardiol. 2004;44:2239-46 pubmed
Most P, Pleger S, Völkers M, Heidt B, Boerries M, Weichenhan D, et al. Cardiac adenoviral S100A1 gene delivery rescues failing myocardium. J Clin Invest. 2004;114:1550-63 pubmed
Jordan T, Jiang H, Li H, DiMario J. Inhibition of ryanodine receptor 1 in fast skeletal muscle fibers induces a fast-to-slow muscle fiber type transition. J Cell Sci. 2004;117:6175-83 pubmed
Rosenberg P, Hawkins A, Stiber J, Shelton J, Hutcheson K, Bassel Duby R, et al. TRPC3 channels confer cellular memory of recent neuromuscular activity. Proc Natl Acad Sci U S A. 2004;101:9387-92 pubmed
Liu Z, Zhang J, Wang R, Wayne Chen S, Wagenknecht T. Location of divergent region 2 on the three-dimensional structure of cardiac muscle ryanodine receptor/calcium release channel. J Mol Biol. 2004;338:533-45 pubmed
Johnson J, Han Z, Otani K, Ye H, Zhang Y, Wu H, et al. RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. J Biol Chem. 2004;279:24794-802 pubmed
Van Acker K, Bultynck G, Rossi D, Sorrentino V, Boens N, Missiaen L, et al. The 12 kDa FK506-binding protein, FKBP12, modulates the Ca(2+)-flux properties of the type-3 ryanodine receptor. J Cell Sci. 2004;117:1129-37 pubmed
Aracena P, Sanchez G, Donoso P, Hamilton S, Hidalgo C. S-glutathionylation decreases Mg2+ inhibition and S-nitrosylation enhances Ca2+ activation of RyR1 channels. J Biol Chem. 2003;278:42927-35 pubmed
Mulvey C, Ohlendieck K. Use of continuous-elution gel electrophoresis as a preparative tool for blot overlay analysis. Anal Biochem. 2003;319:122-30 pubmed
Ward C, Reiken S, Marks A, Marty I, Vassort G, Lacampagne A. Defects in ryanodine receptor calcium release in skeletal muscle from post-myocardial infarct rats. FASEB J. 2003;17:1517-9 pubmed
Most P, Remppis A, Pleger S, Löffler E, Ehlermann P, Bernotat J, et al. Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance. J Biol Chem. 2003;278:33809-17 pubmed
O Malley K, Jong Y, Gonchar Y, Burkhalter A, Romano C. Activation of metabotropic glutamate receptor mGlu5 on nuclear membranes mediates intranuclear Ca2+ changes in heterologous cell types and neurons. J Biol Chem. 2003;278:28210-9 pubmed
Jiang M, Lokuta A, Farrell E, Wolff M, Haworth R, Valdivia H. Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure. Circ Res. 2002;91:1015-22 pubmed
Choi K, Zhong Y, Hoit B, Grupp I, Hahn H, Dilly K, et al. Defective intracellular Ca(2+) signaling contributes to cardiomyopathy in Type 1 diabetic rats. Am J Physiol Heart Circ Physiol. 2002;283:H1398-408 pubmed
Xiao B, Masumiya H, Jiang D, Wang R, Sei Y, Zhang L, et al. Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors). J Biol Chem. 2002;277:41778-85 pubmed 出版商
Hong C, Cho M, Kwak Y, Song C, Lee Y, Lim J, et al. Cardiac remodeling and atrial fibrillation in transgenic mice overexpressing junctin. FASEB J. 2002;16:1310-2 pubmed
Li Y, Kranias E, Mignery G, Bers D. Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circ Res. 2002;90:309-16 pubmed
Song L, Guia A, Muth J, Rubio M, Wang S, Xiao R, et al. Ca(2+) signaling in cardiac myocytes overexpressing the alpha(1) subunit of L-type Ca(2+) channel. Circ Res. 2002;90:174-81 pubmed
Antonucci D, Lim S, Vassanelli S, Trimmer J. Dynamic localization and clustering of dendritic Kv2.1 voltage-dependent potassium channels in developing hippocampal neurons. Neuroscience. 2001;108:69-81 pubmed
Kockskamper J, Sheehan K, Bare D, Lipsius S, Mignery G, Blatter L. Activation and propagation of Ca(2+) release during excitation-contraction coupling in atrial myocytes. Biophys J. 2001;81:2590-605 pubmed
Li P, Chen S. Molecular basis of Ca(2)+ activation of the mouse cardiac Ca(2)+ release channel (ryanodine receptor). J Gen Physiol. 2001;118:33-44 pubmed
Lunde P, Dahlstedt A, Bruton J, Lannergren J, Thoren P, Sejersted O, et al. Contraction and intracellular Ca(2+) handling in isolated skeletal muscle of rats with congestive heart failure. Circ Res. 2001;88:1299-305 pubmed
Yusufi A, Cheng J, Thompson M, Dousa T, Warner G, Walker H, et al. cADP-ribose/ryanodine channel/Ca2+-release signal transduction pathway in mesangial cells. Am J Physiol Renal Physiol. 2001;281:F91-F102 pubmed
Liu Z, Zhang J, Sharma M, Li P, Chen S, Wagenknecht T. Three-dimensional reconstruction of the recombinant type 3 ryanodine receptor and localization of its amino terminus. Proc Natl Acad Sci U S A. 2001;98:6104-9 pubmed
Ortenblad N, Lunde P, Levin K, Andersen J, Pedersen P. Enhanced sarcoplasmic reticulum Ca(2+) release following intermittent sprint training. Am J Physiol Regul Integr Comp Physiol. 2000;279:R152-60 pubmed
Yamada K, Kanter E, Newatia A. Long-chain acylcarnitine induces Ca2+ efflux from the sarcoplasmic reticulum. J Cardiovasc Pharmacol. 2000;36:14-21 pubmed
Budde T, Sieg F, Braunewell K, Gundelfinger E, Pape H. Ca2+-induced Ca2+ release supports the relay mode of activity in thalamocortical cells. Neuron. 2000;26:483-92 pubmed
Hirata Y, Nakahata N, Ohizumi Y. Identification of a 97-kDa mastoparan-binding protein involving in Ca(2+) release from skeletal muscle sarcoplasmic reticulum. Mol Pharmacol. 2000;57:1235-42 pubmed
Khoo K, Han M, Park J, Chae S, Kim U, Lee H, et al. Localization of the cyclic ADP-ribose-dependent calcium signaling pathway in hepatocyte nucleus. J Biol Chem. 2000;275:24807-17 pubmed
Chan S, Mayne M, Holden C, Geiger J, Mattson M. Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons. J Biol Chem. 2000;275:18195-200 pubmed
Johansson C, Lannergren J, Lunde P, Vennstrom B, Thoren P, Westerblad H. Isometric force and endurance in soleus muscle of thyroid hormone receptor-alpha(1)- or -beta-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2000;278:R598-603 pubmed
Schmidt U, del Monte F, Miyamoto M, Matsui T, Gwathmey J, Rosenzweig A, et al. Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase. Circulation. 2000;101:790-6 pubmed
Arrio Dupont M, Foucault G, Vacher M, Devaux P, Cribier S. Translational diffusion of globular proteins in the cytoplasm of cultured muscle cells. Biophys J. 2000;78:901-7 pubmed
Murayama T, Oba T, Katayama E, Oyamada H, Oguchi K, Kobayashi M, et al. Further characterization of the type 3 ryanodine receptor (RyR3) purified from rabbit diaphragm. J Biol Chem. 1999;274:17297-308 pubmed
Sei Y, Gallagher K, Basile A. Skeletal muscle type ryanodine receptor is involved in calcium signaling in human B lymphocytes. J Biol Chem. 1999;274:5995-6002 pubmed
Xu K, Huso D, Dawson T, Bredt D, Becker L. Nitric oxide synthase in cardiac sarcoplasmic reticulum. Proc Natl Acad Sci U S A. 1999;96:657-62 pubmed
Anger M, Lompre A, Vallot O, Marotte F, Rappaport L, Samuel J. Cellular distribution of Ca2+ pumps and Ca2+ release channels in rat cardiac hypertrophy induced by aortic stenosis. Circulation. 1998;98:2477-86 pubmed
Protasi F, Franzini Armstrong C, Allen P. Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle. J Cell Biol. 1998;140:831-42 pubmed
Chen S, Airey J, MacLennan D. Positioning of major tryptic fragments in the Ca2+ release channel (ryanodine receptor) resulting from partial digestion of rabbit skeletal muscle sarcoplasmic reticulum. J Biol Chem. 1993;268:22642-9 pubmed
Liu G, Pessah I. Molecular interaction between ryanodine receptor and glycoprotein triadin involves redox cycling of functionally important hyperreactive sulfhydryls. J Biol Chem. 1994;269:33028-34 pubmed
Airey J, Grinsell M, Jones L, Sutko J, Witcher D. Three ryanodine receptor isoforms exist in avian striated muscles. Biochemistry. 1993;32:5739-45 pubmed
Airey J, Beck C, Murakami K, Tanksley S, Deerinck T, Ellisman M, et al. Identification and localization of two triad junctional foot protein isoforms in mature avian fast twitch skeletal muscle. J Biol Chem. 1990;265:14187-94 pubmed
Olivares E, Tanksley S, Airey J, Beck C, Ouyang Y, Deerinck T, et al. Nonmammalian vertebrate skeletal muscles express two triad junctional foot protein isoforms. Biophys J. 1991;59:1153-63 pubmed
Walton P, Airey J, Sutko J, Beck C, Mignery G, Sudhof T, et al. Ryanodine and inositol trisphosphate receptors coexist in avian cerebellar Purkinje neurons. J Cell Biol. 1991;113:1145-57 pubmed
产品信息
产品类型 :
抗体
产品名称 :
RyR1单克隆抗体(34C)
目录# :
MA3-925
规格 :
100微升
价格 :
美国399.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Amphibian, Bovine, Canine, Chicken, Fish, Human, Mouse, Mustelid, Non-human primate, Ovine, Rabbit, Rat
应用 :
Immunohistochemistry (Frozen): 1:1,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:5,000
物种 :
Amphibian, Bovine, Canine, Chicken, Fish, Human, Mouse, Mustelid, Non-human primate, Ovine, Rabbit, Rat
克隆 :
34C
抗体亚型 :
IgG1
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Ryanodine receptors have been shown to play critical roles in the intracellular Ca2+ signaling occurring during cell activation in muscle cells and non-muscled cells. Ryanodine receptor, ~500 kDa, can be isolated from a variety of cell types such as lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscles, cardiac muscle and brain tissues.
免疫原 :
Partially purified chicken pectoral muscle ryanodine receptor.
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Frozen): 1:1,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:5,000
别名 :
AI528790; calcium release channel; calcium release channel (ryanodine receptor 1); calcium release channel protein; CCO; central core disease of muscle; CRC; CRC1, RYR1; halothane; LOW QUALITY PROTEIN: ryanodine receptor 1; MHS; MHS1; porcine stress syndrome; PPP1R137; protein phosphatase 1, regulatory subunit 137; ryanodine receptor; ryanodine receptor 1; ryanodine receptor 1 (skeletal); ryanodine receptor 1, skeletal muscle; ryanodine receptor 1-like, skeletal muscle; RYDR; Ryr; Ryr1; RYR-1; Ryr1l; sarcoplasmic reticulum calcium release channel; skeletal muscle calcium release channel; Skeletal muscle ryanodine receptor; skeletal muscle-type ryanodine receptor; skrr; type 1 ryanodine receptor; type 1-like ryanodine receptor; unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国