产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD44 Monoclonal Antibody (Hermes-1)
目录 :
MA4400
规格 :
200微克
价格 :
美国453
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
HERMES-1
反应物种 :
domestic goat, African green monkey, 人类, 小鼠, 牛, 家羊, domestic rabbit
应用 :
免疫组化, 免疫细胞化学, 中和反应, 免疫沉淀, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 26
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 人类; 图 3a
Abdel Mohsen M, Chavez L, Tandon R, Chew G, Deng X, Danesh A, et al. Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation. PLoS Pathog. 2016;12:e1005677 pubmed 出版商
  • 抑制或激活实验; 人类
Dong F, Eibach M, Bartsch J, Dolga A, Schlomann U, Conrad C, et al. The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells. Neuro Oncol. 2015;17:1474-85 pubmed 出版商
  • 免疫组化; 小鼠
Ferjancic S, Gil Bernabé A, Hill S, Allen P, Richardson P, Sparey T, et al. VCAM-1 and VAP-1 recruit myeloid cells that promote pulmonary metastasis in mice. Blood. 2013;121:3289-97 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
  • 免疫细胞化学; African green monkey; 1:50
Lamontagne C, Grandbois M. PKC-induced stiffening of hyaluronan/CD44 linkage; local force measurements on glioma cells. Exp Cell Res. 2008;314:227-36 pubmed
  • 抑制或激活实验; 人类
Ellis I, Schor A, Schor S. EGF AND TGF-alpha motogenic activities are mediated by the EGF receptor via distinct matrix-dependent mechanisms. Exp Cell Res. 2007;313:732-41 pubmed
  • 抑制或激活实验; 人类
Tsujimura S, Saito K, Kohno K, Tanaka Y. Fragmented hyaluronan induces transcriptional up-regulation of the multidrug resistance-1 gene in CD4+ T cells. J Biol Chem. 2006;281:38089-97 pubmed
K xf6 lln L, Salem O, Valli J, Hansen C, McConnell G. Label2label: training a neural network to selectively restore cellular structures in fluorescence microscopy. J Cell Sci. 2022;135: pubmed 出版商
Kong C, Ordo xf1 ez A, Turner S, Tremaine T, Muter J, Lucas E, et al. Embryo biosensing by uterine natural killer cells determines endometrial fate decisions at implantation. FASEB J. 2021;35:e21336 pubmed 出版商
Ko J, Kim H, Jeong H, Lee H, Oh J. Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis. Cell Rep. 2020;30:3806-3820.e6 pubmed 出版商
Reeves S, Barrow K, Rich L, White M, Shubin N, Chan C, et al. Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases. Front Immunol. 2019;10:3159 pubmed 出版商
Wu M, Chen Y, Kim M, Chang C, Gampala S, Zhang Y, et al. Epithelial-Mesenchymal Transition Directs Stem Cell Polarity via Regulation of Mitofusin. Cell Metab. 2019;29:993-1002.e6 pubmed 出版商
Learn G, McClellan P, Knapik D, Cumsky J, Webster Wood V, Anderson J, et al. Woven collagen biotextiles enable mechanically functional rotator cuff tendon regeneration during repair of segmental tendon defects in vivo. J Biomed Mater Res B Appl Biomater. 2019;107:1864-1876 pubmed 出版商
Chiang T, Lin M, Tsai M, Chen C, Jang L, Lee F. ADP-ribosylation factor-like 4A interacts with Robo1 to promote cell migration by regulating Cdc42 activation. Mol Biol Cell. 2019;30:69-81 pubmed 出版商
D Agostino G, Saporito A, Cecchinato V, Silvestri Y, Borgeat A, Anselmi L, et al. Lidocaine inhibits cytoskeletal remodelling and human breast cancer cell migration. Br J Anaesth. 2018;121:962-968 pubmed 出版商
Tarafder S, Gulko J, Sim K, Yang J, Cook J, Lee C. Engineered Healing of Avascular Meniscus Tears by Stem Cell Recruitment. Sci Rep. 2018;8:8150 pubmed 出版商
Oyama M, Kariya Y, Kariya Y, Matsumoto K, Kanno M, Yamaguchi Y, et al. Biological role of site-specific O-glycosylation in cell adhesion activity and phosphorylation of osteopontin. Biochem J. 2018;475:1583-1595 pubmed 出版商
Surendran S, Siddappa G, Mohan A, Hicks W, Jayaprakash V, Mimikos C, et al. Cancer stem cell and its niche in malignant progression of oral potentially malignant disorders. Oral Oncol. 2017;75:140-147 pubmed 出版商
Ozdemir T, Fowler E, Liu S, Harrington D, Witt R, Farach Carson M, et al. Tuning Hydrogel Properties to Promote the Assembly of Salivary Gland Spheroids in 3D. ACS Biomater Sci Eng. 2016;2:2217-2230 pubmed
Kariya Y, Kariya Y, Saito T, Nishiyama S, Honda T, Tanaka K, et al. Increased cerebrospinal fluid osteopontin levels and its involvement in macrophage infiltration in neuromyelitis optica. BBA Clin. 2015;3:126-34 pubmed 出版商
Hinek A, Smith A, Cutiongco E, Callahan J, Gripp K, Weksberg R. Decreased elastin deposition and high proliferation of fibroblasts from Costello syndrome are related to functional deficiency in the 67-kD elastin-binding protein. Am J Hum Genet. 2000;66:859-72 pubmed
Maaser K, Wolf K, Klein C, Niggemann B, Zanker K, Brocker E, et al. Functional hierarchy of simultaneously expressed adhesion receptors: integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matrices. Mol Biol Cell. 1999;10:3067-79 pubmed
Kubens B, Zanker K. Differences in the migration capacity of primary human colon carcinoma cells (SW480) and their lymph node metastatic derivatives (SW620). Cancer Lett. 1998;131:55-64 pubmed
Trautmann A, Feuerstein B, Ernst N, Brocker E, Klein C. Heterotypic cell-cell adhesion of human mast cells to fibroblasts. Arch Dermatol Res. 1997;289:194-203 pubmed
Picker L, de los Toyos J, Telen M, Haynes B, Butcher E. Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors. J Immunol. 1989;142:2046-51 pubmed
Picker L, Nakache M, Butcher E. Monoclonal antibodies to human lymphocyte homing receptors define a novel class of adhesion molecules on diverse cell types. J Cell Biol. 1989;109:927-37 pubmed
Jalkanen S, Bargatze R, Herron L, Butcher E. A lymphoid cell surface glycoprotein involved in endothelial cell recognition and lymphocyte homing in man. Eur J Immunol. 1986;16:1195-202 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD44 Monoclonal Antibody (Hermes-1)
目录# :
MA4400
规格 :
200微克
定价 :
美国453
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
Bovine, Goat, Human, Ovine, Rabbit
应用 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:200, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Neutralization: Assay-dependent
物种 :
Bovine, Goat, Human, Ovine, Rabbit
克隆 :
Hermes-1
抗体亚型 :
IgG2a
储存 :
-20°C
描述 :
CD44 cell surface antigen is a 100 kDa type 1 transmembrane glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. CD44 is expressed by hematopoietic, non-hematopoietic cells, epithelial tissues, and to filopodia in cultured keratinocytes. Further, bone marrow myeloid cells and memory T cells express CD44 at high levels, and peripheral B and T cells can upregulate the expression of CD44 in response to certain stimulatory events. Transcripts for the CD44 gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full-length nature of some of these variants have not been determined. Alternative splicing is the basis for the structural and functional diversity of the CD44 protein. Diseases associated with CD44 dysfunction include superficial keratitis and lichen sclerosus. CD44 also may be related to tumor metastasis formation.
免疫原 :
80 - 95 kDa lymphocyte surface glycoprotein H-CAM (CD44).
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:200, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Neutralization: Assay-dependent
别名 :
AU023126; AW121933; AW146109; Bovine CD44; CD44; CD44 antigen; CD44 antigen-like protein; CD44 molecule; CD44 molecule (Indian blood group); CD44 protein; CD44 variant; CD44A; CD44-like protein; CDW44; cell surface glycoprotein CD44; Cell surface glycoprotein CD44 (hyaluronate binding protein); cell-surface glycoprotein; chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; Epican; extracellular matrix receptor III; extracellular matrix receptor-III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronan receptor; Hyaluronate receptor; IN; LHR; Ly-24; lymphocyte antigen 24; lymphocyte surface antigen precursor CD44; MC56; MDU2; MDU3; METAA; MIC4; PGP I; Pgp1; PGP-1; PGPI; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; putative Bos taurus CD44; RHAMM; sCD 44; sCD44; soluble CD 44; soluble CD44
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国