产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD44单克隆抗体(1M7.8。 1)
目录 :
MA4405
规格 :
500微克
价格 :
美国453
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
1M7.8.1
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片
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文章摘录数: 11
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
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| Attinger A, MacDonald H, Acha Orbea H. Lymphoid environment limits superantigen and antigen-induced T cell proliferation at high precursor frequency. Eur J Immunol. 2001;31:884-93 pubmed
|
Voyle R, Beermann F, Lees R, Schumann J, Zimmer J, Held W, et al. Ligand-dependent inhibition of CD1d-restricted NKT cell development in mice transgenic for the activating receptor Ly49D. J Exp Med. 2003;197:919-25 pubmed
| |
Oliferenko S, Paiha K, Harder T, Gerke V, Schwärzler C, Schwarz H, et al. Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton. J Cell Biol. 1999;146:843-54 pubmed
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Pavlovitch J, Hulier E, Rizk Rabin M, Marussig M, Mazier D, Joffret M, et al. Resistance to murine AIDS in offspring of mice infected with LP-BM5. Role of CD8 T cells. J Immunol. 1996;156:4757-63 pubmed
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Chu E, Hobbs M, Wilson C, Romball C, Linsley P, Weigle W. Intervention of CD4+ cell subset shifts and autoimmunity in the BXSB mouse by murine CTLA4Ig. J Immunol. 1996;156:1262-8 pubmed
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Walker P, Ohteki T, Lopez J, MacDonald H, Maryanski J. Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response. J Immunol. 1995;155:3443-52 pubmed
| |
Lesley J, Trowbridge I. Genetic characterization of a polymorphic murine cell-surface glycoprotein. Immunogenetics. 1982;15:313-20 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
CD44单克隆抗体(1M7.8。 1)
目录# :
MA4405
规格 :
500微克
定价 :
美国453
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:100, Immunoprecipitation: Assay-dependent, Inhibition Assays: Assay-dependent, Western Blot: Assay-dependent
物种 :
人类, 小鼠
克隆 :
1M7.8.1
抗体亚型 :
IgG2b
储存 :
-20°C
描述 :
CD44 cell surface antigen is a 100 kDa type 1 transmembrane glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. CD44 is expressed by hematopoietic, non-hematopoietic cells, epithelial tissues, and to filopodia in cultured keratinocytes. Further, bone marrow myeloid cells and memory T cells express CD44 at high levels, and peripheral B and T cells can upregulate the expression of CD44 in response to certain stimulatory events. Transcripts for the CD44 gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full-length nature of some of these variants have not been determined. Alternative splicing is the basis for the structural and functional diversity of the CD44 protein. Diseases associated with CD44 dysfunction include superficial keratitis and lichen sclerosus. CD44 also may be related to tumor metastasis formation.
免疫原 :
Mouse 80-95 kD lymphocyte surface glycoprotein H-CAM (CD44).
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:100, Immunoprecipitation: Assay-dependent, Inhibition Assays: Assay-dependent, Western Blot: Assay-dependent
别名 :
AU023126; AW121933; AW146109; Bovine CD44; CD44; CD44 antigen; CD44 antigen-like protein; CD44 molecule; CD44 molecule (Indian blood group); CD44 protein; CD44 variant; CD44A; CD44-like protein; CDW44; cell surface glycoprotein CD44; Cell surface glycoprotein CD44 (hyaluronate binding protein); cell-surface glycoprotein; chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; Epican; extracellular matrix receptor III; extracellular matrix receptor-III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronan receptor; Hyaluronate receptor; IN; LHR; Ly-24; lymphocyte antigen 24; lymphocyte surface antigen precursor CD44; MC56; MDU2; MDU3; METAA; MIC4; PGP I; Pgp1; PGP-1; PGPI; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; putative Bos taurus CD44; RHAMM; sCD 44; sCD44; soluble CD 44; soluble CD44
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公司信息
赛默飞世尔