产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CDK5 Antibody Cocktail
目录 :
MA5-11291
规格 :
500微升
价格 :
美国472
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DC17, DC34
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 5
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:5000
Ramos Miguel A, Meana J, Garcia Sevilla J. Cyclin-dependent kinase-5 and p35/p25 activators in schizophrenia and major depression prefrontal cortex: basal contents and effects of psychotropic medications. Int J Neuropsychopharmacol. 2013;16:683-9 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400
  • 免疫印迹; 小鼠; 1:1000
Shi L, Yang W, Chen X, Zhang J, Yang P, Hu X, et al. The protective effects of tanshinone IIA on neurotoxicity induced by ?-amyloid protein through calpain and the p35/Cdk5 pathway in primary cortical neurons. Neurochem Int. 2012;61:227-35 pubmed 出版商
  • 免疫印迹; 大鼠
Ramos Miguel A, García Sevilla J. Crosstalk between cdk5 and MEK-ERK signalling upon opioid receptor stimulation leads to upregulation of activator p25 and MEK1 inhibition in rat brain. Neuroscience. 2012;215:17-30 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:400
  • 免疫印迹; 大鼠; 1:1000
Jordà E, Verdaguer E, Canudas A, Jimenez A, Garcia De Arriba S, Allgaier C, et al. Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium. Neuroscience. 2005;134:1001-11 pubmed
Jordà E, Verdaguer E, Jimenez A, Canudas A, Rimbau V, Camps P, et al. (+/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration. J Alzheimers Dis. 2004;6:577-83; discussion 673-81 pubmed
图像
图像 1 :
赛默飞世尔 MA5-11291 图像 1
图像 2 :
赛默飞世尔 MA5-11291 图像 2
HeLa cells were lysed 72 hours after transfection. Cells were transfected with Transfection Reagent alone (Lane 1), 100nM ON-TARGETplus siCONTROL Non-Targeting Pool (Lane 2), or 100nM ONTARGETplus CDK5 siRNA (Lane 3). Western blot data for GAPDH is included as a control for equal protein loading.
图像 3 :
赛默飞世尔 MA5-11291 图像 3
产品信息
产品类型 :
抗体
产品名称 :
CDK5 Antibody Cocktail
目录# :
MA5-11291
规格 :
500微升
定价 :
美国472
克隆性 :
Cocktail
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: Assay-dependent, Immunoprecipitation: 6 µg/mg protein lysate, Western Blot: 1-2 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
DC17, DC34
抗体亚型 :
IgG1
储存 :
4° C
描述 :
Cyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in the kidneys, testes, and ovaries. And Its activity has been detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity; however, Cdk5 is not activated bycyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits, called p35 and p39. These two activators regulate the spatial and temporal expression of active Cdk5, restricting its activity primarily to post-mitotic neurons.
免疫原 :
重组cdk5蛋白
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay-dependent, Immunoprecipitation: 6 µg/mg protein lysate, Western Blot: 1-2 µg/mL
别名 :
AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国