产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
MAGE1单克隆抗体(MA454)
目录 :
MA5-11338
规格 :
500微升
价格 :
美国429
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MA454
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 7
| 出版应用/物种/样本/稀释 | 参考文献 |
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| Jacobs J, Brasseur F, Hulsbergen van de Kaa C, van de Rakt M, Figdor C, Adema G, et al. Cancer-germline gene expression in pediatric solid tumors using quantitative real-time PCR. Int J Cancer. 2007;120:67-74 pubmed
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| Gjerstorff M, Johansen L, Nielsen O, Kock K, Ditzel H. Restriction of GAGE protein expression to subpopulations of cancer cells is independent of genotype and may limit the use of GAGE proteins as targets for cancer immunotherapy. Br J Cancer. 2006;94:1864-73 pubmed
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Wischnewski F, Pantel K, Schwarzenbach H. Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. Mol Cancer Res. 2006;4:339-49 pubmed
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Xu X, Chu A, Pasha T, Elder D, Zhang P. Immunoprofile of MITF, tyrosinase, melan-A, and MAGE-1 in HMB45-negative melanomas. Am J Surg Pathol. 2002;26:82-7 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
MAGE1单克隆抗体(MA454)
目录# :
MA5-11338
规格 :
500微升
定价 :
美国429
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunohistochemistry (Paraffin): 1:12.5-1:25, Western Blot: 0.5-1.0 µg/mL
物种 :
人类
克隆 :
MA454
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanoma associated with antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various hisological tyoes (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
免疫原 :
Partially purified, full length recombinant human MAGE-1 protein
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:12.5-1:25, Western Blot: 0.5-1.0 µg/mL
别名 :
antigen MZ2-E; antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5; cancer/testis antigen 1.1; cancer/testis antigen family 1, member 1; CD228; CT1.1; mage 1; MAGE family member A1; MAGE1; mage-1; MAGE-1 antigen; MAGE1A; MAGEA1; Mage-a1; MAP97; melanoma antigen family A 1; melanoma antigen family A, 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); melanoma antigen family A1; melanoma antigen MAGE-1; melanoma antigen, family A, 1; melanoma-associated antigen 1; melanoma-associated antigen MZ2-E; Melanoma-associated antigen p97; melanoma-associated antigen p97, isoform 2; melanotransferrin; MELTF; membrane-bound transferrin-like protein; Mfi2; MTf; MTF1
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公司信息
赛默飞世尔