产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
细胞角蛋白15单克隆抗体(LHK15)
目录 :
MA5-11344
规格 :
500微升
价格 :
美国374
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
LHK15
反应物种 :
酵母菌目, 人类, 小鼠, 大鼠, 犬, 牛, 家羊
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 53
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 图 8a
Gesteira T, Sun M, Coulson Thomas Y, Yamaguchi Y, Yeh L, Hascall V, et al. Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation. Invest Ophthalmol Vis Sci. 2017;58:4407-4421 pubmed 出版商
  • 免疫组化; 犬; 1:50; 图 5d,6d,7d,8d
Watanabe K, Chambers J, Uchida K, Nibe K, Ushio N, Horiuchi N, et al. A cutaneous mixed tumor in a dog. J Vet Med Sci. 2017;79:670-673 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 2c
Shin H, Yoon J, Koh W, Kim J, Kim C, Han K, et al. Nonpigmented hair removal using photodynamic therapy in animal model. Lasers Surg Med. 2016;48:748-762 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 3c
Mikhailova A, Ilmarinen T, Ratnayake A, Petrovski G, Uusitalo H, Skottman H, et al. Human pluripotent stem cell-derived limbal epithelial stem cells on bioengineered matrices for corneal reconstruction. Exp Eye Res. 2016;146:26-34 pubmed 出版商
  • 免疫细胞化学; 人类; 1:25; 图 2a
Fridriksdottir A, Kim J, Villadsen R, Klitgaard M, Hopkinson B, Petersen O, et al. Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture. Nat Commun. 2015;6:8786 pubmed 出版商
  • 免疫细胞化学; 人类; 1:25
  • 免疫组化; 人类; 1:25
Balk Møller E, Kim J, Hopkinson B, Timmermans Wielenga V, Petersen O, Villadsen R. A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched. Am J Pathol. 2014;184:1198-208 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3
Leung Y, Kandyba E, Chen Y, Ruffins S, Kobielak K. Label retaining cells (LRCs) with myoepithelial characteristic from the proximal acinar region define stem cells in the sweat gland. PLoS ONE. 2013;8:e74174 pubmed 出版商
  • 免疫组化; 小鼠
Hughes M, Jiang T, Lin S, Leung Y, Kobielak K, Widelitz R, et al. Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis. J Invest Dermatol. 2014;134:24-32 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1500
Petersson M, Frances D, Niemann C. Lineage tracing of hair follicle stem cells in epidermal whole mounts. Methods Mol Biol. 2013;989:45-60 pubmed 出版商
  • 免疫组化; 人类; 1:250
Cayirli M, Kose O, Demiriz M. Clinical, dermoscopic and immunohistochemical assessment of actinic keratoses and evaluation of the effectiveness of diclofenac therapy with immunohistochemical analysis. Arch Dermatol Res. 2013;305:389-95 pubmed 出版商
  • 免疫组化; 人类; 1:100
Higa K, Kato N, Yoshida S, Ogawa Y, Shimazaki J, Tsubota K, et al. Aquaporin 1-positive stromal niche-like cells directly interact with N-cadherin-positive clusters in the basal limbal epithelium. Stem Cell Res. 2013;10:147-55 pubmed 出版商
  • 流式细胞仪; 人类; 1:100
Fogarty S, Patel I, Trevisan J, Nakamura T, Hirschmugl C, Fullwood N, et al. Sub-cellular spectrochemical imaging of isolated human corneal cells employing synchrotron radiation-based Fourier-transform infrared microspectroscopy. Analyst. 2013;138:240-8 pubmed 出版商
  • 免疫组化; 人类; 1:100
Wang X, Shi Y, Zhou Q, Liu X, Xu S, Lei T. Detailed histological structure of human hair follicle bulge region at different ages: a visible niche for nesting adult stem cells. J Huazhong Univ Sci Technolog Med Sci. 2012;32:648-656 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
García Zaragoza E, Pérez Tavarez R, Ballester A, Lafarga V, Jiménez Reinoso A, Ramirez A, et al. Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland. Dev Biol. 2012;372:28-44 pubmed 出版商
  • 免疫组化; 小鼠
Costa C, Santos M, Martinez Fernandez M, Duenas M, Lorz C, García Escudero R, et al. E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis. Oncogene. 2013;32:2937-51 pubmed 出版商
  • 免疫组化; 小鼠
Garza L, Liu Y, Yang Z, Alagesan B, Lawson J, Norberg S, et al. Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Sci Transl Med. 2012;4:126ra34 pubmed 出版商
  • 免疫组化; 人类; 1:250
Mahalingam M, Richards J, Selim M, Muzikansky A, Hoang M. An immunohistochemical comparison of cytokeratin 7, cytokeratin 15, cytokeratin 19, CAM 5.2, carcinoembryonic antigen, and nestin in differentiating porocarcinoma from squamous cell carcinoma. Hum Pathol. 2012;43:1265-72 pubmed 出版商
  • 免疫组化; 人类; 1:100
Kuo T, Chen C, Baron D, Onder T, Loewer S, Almeida S, et al. Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nat Cell Biol. 2011;13:1214-23 pubmed 出版商
  • 免疫组化; 小鼠; 1:50
Haffner M, Chaux A, Meeker A, Esopi D, Gerber J, Pellakuru L, et al. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget. 2011;2:627-37 pubmed
  • 免疫组化; 人类; 1:150; 表 3
Chui J, Coroneo M, Tat L, Crouch R, Wakefield D, Di Girolamo N. Ophthalmic pterygium: a stem cell disorder with premalignant features. Am J Pathol. 2011;178:817-27 pubmed 出版商
  • 免疫组化; 人类
Garza L, Yang C, Zhao T, Blatt H, Lee M, He H, et al. Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells. J Clin Invest. 2011;121:613-22 pubmed 出版商
  • 免疫组化; 人类
Qi H, Zheng X, Yuan X, Pflugfelder S, Li D. Potential localization of putative stem/progenitor cells in human bulbar conjunctival epithelium. J Cell Physiol. 2010;225:180-5 pubmed 出版商
  • 免疫组化; 小鼠
Lorz C, García Escudero R, Segrelles C, Garin M, Ariza J, Santos M, et al. A functional role of RB-dependent pathway in the control of quiescence in adult epidermal stem cells revealed by genomic profiling. Stem Cell Rev. 2010;6:162-77 pubmed 出版商
  • 免疫组化; 人类
Laga A, Lai C, Zhan Q, Huang S, Velazquez E, Yang Q, et al. Expression of the embryonic stem cell transcription factor SOX2 in human skin: relevance to melanocyte and merkel cell biology. Am J Pathol. 2010;176:903-13 pubmed 出版商
  • 免疫组化; 人类; 1:100
  • 免疫组化; 小鼠; 1:100
Amoh Y, Hoffman R. Isolation and culture of hair follicle pluripotent stem (hfPS) cells and their use for nerve and spinal cord regeneration. Methods Mol Biol. 2010;585:401-20 pubmed 出版商
  • 免疫细胞化学; 人类
Guo A, Jahoda C. An improved method of human keratinocyte culture from skin explants: cell expansion is linked to markers of activated progenitor cells. Exp Dermatol. 2009;18:720-6 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Amoh Y, Kanoh M, Niiyama S, Hamada Y, Kawahara K, Sato Y, et al. Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral-nerve injury: an advantageous alternative to ES and iPS cells. J Cell Biochem. 2009;107:1016-20 pubmed 出版商
  • 流式细胞仪; 人类; 1:300
  • 免疫组化; 人类; 1:300
Inoue K, Aoi N, Sato T, Yamauchi Y, Suga H, Eto H, et al. Differential expression of stem-cell-associated markers in human hair follicle epithelial cells. Lab Invest. 2009;89:844-56 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫组化; 人类
  • 免疫印迹; 人类
Celis J, Gromova I, Cabezon T, Gromov P, Shen T, Timmermans Wielenga V, et al. Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease. Mol Oncol. 2007;1:321-49 pubmed 出版商
  • 免疫组化; 人类
  • 免疫印迹; 人类; 1:500
Celis J, Moreira J, Gromova I, Cabezon T, Gromov P, Shen T, et al. Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia. Mol Oncol. 2007;1:97-119 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50
Stout G, Blasco M. Genetic dissection of the mechanisms underlying telomere-associated diseases: impact of the TRF2 telomeric protein on mouse epidermal stem cells. Dis Model Mech. 2009;2:139-56 pubmed 出版商
  • 免疫组化; 人类; 1:50
Choi C, Park H, Kim Y, Lee S, Cho K. Elastic fiber staining and cytokeratin 15 expression pattern in trichoepithelioma and basal cell carcinoma. J Dermatol. 2008;35:499-502 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Kanoh M, Amoh Y, Sato Y, Katsuoka K. Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors. Eur J Dermatol. 2008;18:518-23 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
Amoh Y, Li L, Katsuoka K, Hoffman R. Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function. Cell Cycle. 2008;7:1865-9 pubmed
  • 免疫组化; 人类; 1:80
Pozdnyakova O, Mahalingam M. Involvement of the bulge region in primary scarring alopecia. J Cutan Pathol. 2008;35:922-5 pubmed 出版商
  • 免疫细胞化学; 家羊; 1:100
Liu Y, Zhou H, Gao F. Isolation and identification of stem cells from adult cashmere goat skin. Int J Dermatol. 2008;47:551-6 pubmed 出版商
  • 免疫细胞化学; 家羊
Islam M, Zhou H. Isolation and characterization of putative epidermal stem cells derived from Cashmere goat fetus. Eur J Dermatol. 2007;17:302-8 pubmed
  • 免疫组化; 小鼠; 1:50
Iida M, Ihara S, Matsuzaki T. Hair cycle-dependent changes of alkaline phosphatase activity in the mesenchyme and epithelium in mouse vibrissal follicles. Dev Growth Differ. 2007;49:185-95 pubmed
  • 免疫组化; 人类; 1:40
  • 免疫组化; 酵母菌目; 1:40
Raposio E, Guida C, Baldelli I, Curto M, Fiocca R, Kunkl A, et al. Characterization of multipotent cells from human adult hair follicles. Toxicol In Vitro. 2007;21:320-3 pubmed
  • 免疫组化; 人类; 1:200
Murakami D, Yamato M, Nishida K, Ohki T, Takagi R, Yang J, et al. Fabrication of transplantable human oral mucosal epithelial cell sheets using temperature-responsive culture inserts without feeder layer cells. J Artif Organs. 2006;9:185-91 pubmed
  • 免疫组化; 人类
Körver J, van Duijnhoven M, Pasch M, Van Erp P, van de Kerkhof P. Assessment of epidermal subpopulations and proliferation in healthy skin, symptomless and lesional skin of spreading psoriasis. Br J Dermatol. 2006;155:688-94 pubmed
  • 免疫组化; 犬; 1:200
Murakami D, Yamato M, Nishida K, Ohki T, Takagi R, Yang J, et al. The effect of micropores in the surface of temperature-responsive culture inserts on the fabrication of transplantable canine oral mucosal epithelial cell sheets. Biomaterials. 2006;27:5518-23 pubmed
  • 免疫组化; 人类
van Duijnhoven M, Körver J, Vissers W, van Vlijmen Willems I, Pasch M, Van Erp P, et al. Effect of calcipotriol on epidermal cell populations in alefacept-treated psoriatic lesions. J Eur Acad Dermatol Venereol. 2006;20:27-33 pubmed
  • 流式细胞仪; 人类
Ohyama M, Terunuma A, Tock C, Radonovich M, Pise Masison C, Hopping S, et al. Characterization and isolation of stem cell-enriched human hair follicle bulge cells. J Clin Invest. 2006;116:249-60 pubmed
  • 免疫组化; 小鼠; 1:100
Amoh Y, Li L, Campillo R, Kawahara K, Katsuoka K, Penman S, et al. Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves. Proc Natl Acad Sci U S A. 2005;102:17734-8 pubmed
  • 免疫组化; 小鼠; 1:100
Amoh Y, Li L, Katsuoka K, Penman S, Hoffman R. Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons. Proc Natl Acad Sci U S A. 2005;102:5530-4 pubmed
  • 免疫组化; 人类
van Duijnhoven M, van de Kerkhof P, Pasch M, Muys L, van Erp P. The combination of the Zenon labeling technique and microscopic image analysis to study cell populations in normal and psoriatic epidermis. J Cutan Pathol. 2005;32:212-9 pubmed
Fujita Y, Komatsu M, Lee S, Kushida Y, Nakayama Nishimura C, Matsumura W, et al. Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa. J Invest Dermatol. 2021;141:198-202.e6 pubmed 出版商
Chu S, Chou C, Huang H, Yen M, Hong H, Chao P, et al. Mechanical stretch induces hair regeneration through the alternative activation of macrophages. Nat Commun. 2019;10:1524 pubmed 出版商
Shi J, Lv Z, Nie M, Lu W, Liu C, Tian Y, et al. Human nail stem cells are retained but hypofunctional during aging. J Mol Histol. 2018;49:303-316 pubmed 出版商
Villadsen R, Fridriksdottir A, Rønnov Jessen L, Gudjonsson T, Rank F, Labarge M, et al. Evidence for a stem cell hierarchy in the adult human breast. J Cell Biol. 2007;177:87-101 pubmed
Langner C, Wegscheider B, Ratschek M, Schips L, Zigeuner R. Keratin immunohistochemistry in renal cell carcinoma subtypes and renal oncocytomas: a systematic analysis of 233 tumors. Virchows Arch. 2004;444:127-34 pubmed
Whitaker Menezes D, Jones S, Friedman T, Korngold R, Murphy G. An epithelial target site in experimental graft-versus-host disease and cytokine-mediated cytotoxicity is defined by cytokeratin 15 expression. Biol Blood Marrow Transplant. 2003;9:559-70 pubmed
产品信息
产品类型 :
抗体
产品名称 :
细胞角蛋白15单克隆抗体(LHK15)
目录# :
MA5-11344
规格 :
500微升
定价 :
美国374
克隆性 :
单克隆
纯度 :
蛋白质A/G
宿主 :
小鼠
反应物种 :
牛, 人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1:100-1:500, Western Blot: 1:100-1:500
物种 :
牛, 人类, 小鼠, 大鼠
克隆 :
LHK15
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Cytokeratin 15 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21. 2.
免疫原 :
A 17-mer synthetic peptide from the C-terminus of human cytokeratin 15
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1:100-1:500, Western Blot: 1:100-1:500
别名 :
AI528832; C K1CO; CK15; CK-15; cytokeratin 15; cytokeratin-15; K15; K1CO; Ka15; keratin 15; keratin 15, type I; keratin complex 1, acidic, gene 15; keratin, type I cytoskeletal 15; Keratin-15; keratin-15, basic; keratin-15, beta; KRT1; Krt1-15; KRT15; krt15 {ECO:0000250; KRTB; type I cytoskeletal 15; type I keratin KA15; UniProtKB:P19012}
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国