产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
增殖细胞核抗原单克隆抗体(PC10), 生物素
目录 :
MA5-11355
规格 :
500微升
价格 :
美国472
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
生物素
克隆名称 :
PC10
反应物种 :
人类, 大鼠, 犬
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 135
参考文献 |
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Sathyan K, Nalinakumari K, Kannan S. H-Ras mutation modulates the expression of major cell cycle regulatory proteins and disease prognosis in oral carcinoma. Mod Pathol. 2007;20:1141-8 pubmed
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Uyanoglu M, Canbek M, Aral E, Husnu Can Baser K. Effects of carvacrol upon the liver of rats undergoing partial hepatectomy. Phytomedicine. 2008;15:226-9 pubmed
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Tataroglu C, Karabacak T, Apa D. Beta-catenin and CD44 expression in keratoacanthoma and squamous cell carcinoma of the skin. Tumori. 2007;93:284-9 pubmed
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Heckmann L, Fiedler J, Mattes T, Dauner M, Brenner R. Interactive effects of growth factors and three-dimensional scaffolds on multipotent mesenchymal stromal cells. Biotechnol Appl Biochem. 2008;49:185-94 pubmed
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Laine H, Doetzlhofer A, Mantela J, Ylikoski J, Laiho M, Roussel M, et al. p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis. J Neurosci. 2007;27:1434-44 pubmed
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Hausser H, Ruegg M, Brenner R, Ksiazek I. Agrin is highly expressed by chondrocytes and is required for normal growth. Histochem Cell Biol. 2007;127:363-74 pubmed
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Lindström M, Jin A, Deisenroth C, White Wolf G, Zhang Y. Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation. Mol Cell Biol. 2007;27:1056-68 pubmed
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Lee J, Kim J, Cho K, Lee M, Cho S, Zhang Y, et al. Modulation of cell proliferation during palatogenesis by the interplay between Tbx3 and Bmp4. Cell Tissue Res. 2007;327:285-92 pubmed
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Hou R, Liu L, Anees S, Hiroyasu S, Sibinga N. The Fat1 cadherin integrates vascular smooth muscle cell growth and migration signals. J Cell Biol. 2006;173:417-29 pubmed
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Yazici A, Tursen U, Apa D, Ikizoglu G, Api H, Baz K, et al. The changes in expression of ICAM-3, Ki-67, PCNA, and CD31 in psoriatic lesions before and after methotrexate treatment. Arch Dermatol Res. 2005;297:249-55 pubmed
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Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher D, et al. Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax. J Biol Chem. 2005;280:35713-22 pubmed
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Refsland E, Livingston D. Interactions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeast. Genetics. 2005;171:923-34 pubmed
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Saylam G, Yücel O, Sungur A, Onerci M. Proliferation, angiogenesis and hormonal markers in juvenile nasopharyngeal angiofibroma. Int J Pediatr Otorhinolaryngol. 2006;70:227-34 pubmed
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Kamalov G, Varma B, Lu L, Sun Y, Weber K, Guntaka R. Expression of the multifunctional Y-box protein, YB-1, in myofibroblasts of the infarcted rat heart. Biochem Biophys Res Commun. 2005;334:239-44 pubmed
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Gruber A, Schmidt P, Url A. Immunohistochemical studies concerning the neuronal cell cycle of the cat using PCNA, Ki-67 and p53 markers. J Vet Med A Physiol Pathol Clin Med. 2004;51:416-9 pubmed
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Narayanan B, Narayanan N, Pittman B, Reddy B. Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model. Clin Cancer Res. 2004;10:7727-37 pubmed
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Cherian Shaw M, Das R, Vandevoort C, Chaffin C. Regulation of steroidogenesis by p53 in macaque granulosa cells and H295R human adrenocortical cells. Endocrinology. 2004;145:5734-44 pubmed
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Naryzhny S, Lee H. Observation of multiple isoforms and specific proteolysis patterns of proliferating cell nuclear antigen in the context of cell cycle compartments and sample preparations. Proteomics. 2003;3:930-6 pubmed
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Chaffin C, Brogan R, Stouffer R, Vandevoort C. Dynamics of Myc/Max/Mad expression during luteinization of primate granulosa cells in vitro: association with periovulatory proliferation. Endocrinology. 2003;144:1249-56 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
增殖细胞核抗原单克隆抗体(PC10), 生物素
目录# :
MA5-11355
规格 :
500微升
定价 :
美国472
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Canine, Human, Non-human primate, Rat
应用 :
Flow Cytometry: 1:200-1:1,000, Immunocytochemistry: 1:20-1:50, Immunohistochemistry (Paraffin): 1:200-1:400, Immunoprecipitation: 2 µg/mL, Western Blot: 1:500
物种 :
Canine, Human, Non-human primate, Rat
克隆 :
PC10
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
PCNA (polymerase delta auxiliary protein) is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e. relevant to prognosis). PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. PCNA is found in the nucleus and is a cofactor of DNA polymerase delta, and acts as a homotrimer and helps increase the processing of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.
免疫原 :
重组大鼠增殖细胞核抗原蛋白
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:200-1:1,000, Immunocytochemistry: 1:20-1:50, Immunohistochemistry (Paraffin): 1:200-1:400, Immunoprecipitation: 2 µg/mL, Western Blot: 1:500
别名 :
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
更多信息或购买 :
公司信息
赛默飞世尔