产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
增殖细胞核抗原单克隆抗体(PC10), 生物素
目录 :
MA5-11355
规格 :
500微升
价格 :
美国472
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
生物素
克隆名称 :
PC10
反应物种 :
人类, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 135
参考文献
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产品信息
产品类型 :
抗体
产品名称 :
增殖细胞核抗原单克隆抗体(PC10), 生物素
目录# :
MA5-11355
规格 :
500微升
定价 :
美国472
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Canine, Human, Non-human primate, Rat
应用 :
Flow Cytometry: 1:200-1:1,000, Immunocytochemistry: 1:20-1:50, Immunohistochemistry (Paraffin): 1:200-1:400, Immunoprecipitation: 2 µg/mL, Western Blot: 1:500
物种 :
Canine, Human, Non-human primate, Rat
克隆 :
PC10
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
PCNA (polymerase delta auxiliary protein) is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e. relevant to prognosis). PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. PCNA is found in the nucleus and is a cofactor of DNA polymerase delta, and acts as a homotrimer and helps increase the processing of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.
免疫原 :
重组大鼠增殖细胞核抗原蛋白
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:200-1:1,000, Immunocytochemistry: 1:20-1:50, Immunohistochemistry (Paraffin): 1:200-1:400, Immunoprecipitation: 2 µg/mL, Western Blot: 1:500
别名 :
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国