产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Alpha-Smooth Muscle Actin Monoclonal Antibody (1A4 (asm-1)), Biotin
目录 :
MA5-11544
规格 :
500微升
价格 :
美国446
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
生物素
克隆名称 :
1A4 (asm-1)
反应物种 :
tiger salamander, 人类, 小鼠, 大鼠, 犬, 鸡, 牛, pigs , 猫, 家羊, domestic rabbit, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 228
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| Nakanishi K, Saito Y, Azuma N, Sasajima T. Cyclic adenosine monophosphate response-element binding protein activation by mitogen-activated protein kinase-activated protein kinase 3 and four-and-a-half LIM domains 5 plays a key role for vein graft intimal hyperplasia. J Vasc Surg. 2013;57:182-93, 193.e1-10 pubmed 出版商
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| Tanwar P, Kaneko Tarui T, Zhang L, TEIXEIRA J. Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis. Hum Mol Genet. 2012;21:4394-405 pubmed
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| Zhu H, Luo S, Wang J, Li X, Wang H, Pu W, et al. Effect of environmental factors on chemoresistance of HepG2 cells by regulating hypoxia-inducible factor-1?. Chin Med J (Engl). 2012;125:1095-103 pubmed
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| Ozcan A, Karslioglu Y, Gunal A, Cermık A, Kurt B, Onguru O. Fascin expression and its potential significance in gastrointestinal stromal tumors. Turk J Gastroenterol. 2011;22:363-8 pubmed
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| Carlucci M, Iacobellis M, Colonna F, Marseglia M, Gambarotti M, Giardina C, et al. Metaplastic carcinoma of the breast with dominant squamous and sebaceous differentiation in the primary tumor and osteochondroid metaplasia in a distant metastasis: report of a case with review of sebaceous differentiation in breast tumors. Int J Surg Pathol. 2012;20:284-96 pubmed 出版商
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| Lin F, Lin Y, Huang C, Chang Y, Tsao N, Chang N, et al. GroEL1, a heat shock protein 60 of Chlamydia pneumoniae, induces lectin-like oxidized low-density lipoprotein receptor 1 expression in endothelial cells and enhances atherogenesis in hypercholesterolemic rabbits. J Immunol. 2011;186:4405-14 pubmed 出版商
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| Wehrum M, Buhimschi I, Salafia C, Thung S, Bahtiyar M, Werner E, et al. Accreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast. Am J Obstet Gynecol. 2011;204:411.e1-411.e11 pubmed 出版商
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| Tanaka S, Sumioka T, Fujita N, Kitano A, Okada Y, Yamanaka O, et al. Suppression of injury-induced epithelial-mesenchymal transition in a mouse lens epithelium lacking tenascin-C. Mol Vis. 2010;16:1194-205 pubmed
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| Ishibashi R, Aoki T, Nishimura M, Hashimoto N, Miyamoto S. Contribution of mast cells to cerebral aneurysm formation. Curr Neurovasc Res. 2010;7:113-24 pubmed
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| Amoh Y, Li L, Katsuoka K, Hoffman R. Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function. Cell Cycle. 2008;7:1865-9 pubmed
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| Miyabayashi T, Yamamoto M, Sato A, Sakano S, Takahashi Y. Indole derivatives sustain embryonic stem cell self-renewal in long-term culture. Biosci Biotechnol Biochem. 2008;72:1242-8 pubmed
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| Sasaki M, Abe R, Fujita Y, Ando S, Inokuma D, Shimizu H. Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type. J Immunol. 2008;180:2581-7 pubmed
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| Higgins D, Kimura K, Bernhardt W, Shrimanker N, Akai Y, Hohenstein B, et al. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest. 2007;117:3810-20 pubmed
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| Zoll J, Fontaine V, Gourdy P, Barateau V, Vilar J, Leroyer A, et al. Role of human smooth muscle cell progenitors in atherosclerotic plaque development and composition. Cardiovasc Res. 2008;77:471-80 pubmed
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| Yang K, Chang W, Chuang C, Hung K, Li E. Antagonizing TGF-beta induced liver fibrosis by a retinoic acid derivative through regulation of ROS and calcium influx. Biochem Biophys Res Commun. 2008;365:484-9 pubmed
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| Gulbahar M, Guvenc T, Yarim M, Kabak Y, Sozgen Y. Mammary fibroadenoma in a lamb. J Vet Sci. 2007;8:423-5 pubmed
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| Yamanaka O, Saika S, Ohnishi Y, Kim Mitsuyama S, Kamaraju A, Ikeda K. Inhibition of p38MAP kinase suppresses fibrogenic reaction in conjunctiva in mice. Mol Vis. 2007;13:1730-9 pubmed
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| Yorulmaz G, Erdogan G, Pestereli H, Savas B, Karaveli F. Epithelioid leiomyosarcoma with rhabdoid features. Wien Klin Wochenschr. 2007;119:557-60 pubmed
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| Mitchell P, Guidot D. Alcohol ingestion by donors amplifies experimental airway disease after heterotopic transplantation. Am J Respir Crit Care Med. 2007;176:1161-8 pubmed
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| Serikov V, Popov B, Mikhailov V, Gupta N, Matthay M. Evidence of temporary airway epithelial repopulation and rare clonal formation by BM-derived cells following naphthalene injury in mice. Anat Rec (Hoboken). 2007;290:1033-45 pubmed
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| Khan M, Kutala V, Vikram D, Wisel S, Chacko S, Kuppusamy M, et al. Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function. Am J Physiol Heart Circ Physiol. 2007;293:H2129-39 pubmed
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| Yamamoto N, Akamatsu H, Hasegawa S, Yamada T, Nakata S, Ohkuma M, et al. Isolation of multipotent stem cells from mouse adipose tissue. J Dermatol Sci. 2007;48:43-52 pubmed
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| Monge M, Colas E, Doll A, Gonzalez M, Gil Moreno A, Planaguma J, et al. ERM/ETV5 up-regulation plays a role during myometrial infiltration through matrix metalloproteinase-2 activation in endometrial cancer. Cancer Res. 2007;67:6753-9 pubmed
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| Saika S, Yamanaka O, Okada Y, Miyamoto T, Kitano A, Flanders K, et al. Effect of overexpression of PPARgamma on the healing process of corneal alkali burn in mice. Am J Physiol Cell Physiol. 2007;293:C75-86 pubmed
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| Firat I, Haktanir Yatkin D, Sontas B, Ekici H. Vulvar leiomyosarcoma in a cat. J Feline Med Surg. 2007;9:435-8 pubmed
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| Somani A, Nguyen J, Milbauer L, Solovey A, Sajja S, Hebbel R. The establishment of murine blood outgrowth endothelial cells and observations relevant to gene therapy. Transl Res. 2007;150:30-9 pubmed
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| Saika S, Yamanaka O, Nishikawa Ishida I, Kitano A, Flanders K, Okada Y, et al. Effect of Smad7 gene overexpression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse model. Arch Ophthalmol. 2007;125:647-54 pubmed
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| Akin M, Demirbilek S, Ay S, Gurunluoglu K, Turkmen E, Tas E, et al. Attenuation of ureteral obstruction-induced renal injury by polyenylphosphatidylcholine. Int J Urol. 2007;14:350-6 pubmed
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| Sun L, Cui M, Wang Z, Feng X, Mao J, Chen P, et al. Mesenchymal stem cells modified with angiopoietin-1 improve remodeling in a rat model of acute myocardial infarction. Biochem Biophys Res Commun. 2007;357:779-84 pubmed
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| Corcione L, Giordano G, Gnetti L, Multinu A, Ferrari S. Oncocytic mucoepidermoid carcinoma of a submandibular gland: a case report and review of the literature. Int J Oral Maxillofac Surg. 2007;36:560-3 pubmed
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| Gun B, Bahadir B, Behzatoglu K, Gun M, Ozdamar S. Elastofibroma: a clinicopathologic and immunohistochemical study of seven cases and literature review. APMIS. 2007;115:115-9 pubmed
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| Vardar E, Gunlusoy B, Arslan M, Kececi S. Myointimoma of the glans penis. Pathol Int. 2007;57:158-61 pubmed
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| Lin F, Chen Y, Chen Y, Wu T, Li C, Chen J, et al. Ginkgo biloba extract inhibits endotoxin-induced human aortic smooth muscle cell proliferation via suppression of toll-like receptor 4 expression and NADPH oxidase activation. J Agric Food Chem. 2007;55:1977-84 pubmed
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| Palmieri K, Mannikarottu A, Chichester P, Kogan B, Leggett R, Whitbeck C, et al. The effects of cyclical oestrogen on bladder and urethral structure and function. BJU Int. 2007;99:171-6 pubmed
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| Cristina C, Díaz Torga G, Goya R, Kakar S, Perez Millán M, Passos V, et al. PTTG expression in different experimental and human prolactinomas in relation to dopaminergic control of lactotropes. Mol Cancer. 2007;6:4 pubmed
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| Saika S, Shirai K, Yamanaka O, Miyazaki K, Okada Y, Kitano A, et al. Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium. Lab Invest. 2007;87:130-8 pubmed
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| Aoki T, Kataoka H, Morimoto M, Nozaki K, Hashimoto N. Macrophage-derived matrix metalloproteinase-2 and -9 promote the progression of cerebral aneurysms in rats. Stroke. 2007;38:162-9 pubmed
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| Kitano A, Saika S, Yamanaka O, Ikeda K, Reinach P, Nakajima Y, et al. Genipin suppresses subconjunctival fibroblast migration, proliferation and myofibroblast transdifferentiation. Ophthalmic Res. 2006;38:355-60 pubmed
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| Guo W, Xu H, Chen J, Yang Y, Jin J, Fu R, et al. Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1. Mol Cell Biochem. 2007;295:167-77 pubmed
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| Yamanaka O, Ikeda K, Saika S, Miyazaki K, Ooshima A, Ohnishi Y. Gene transfer of Smad7 modulates injury-induced conjunctival wound healing in mice. Mol Vis. 2006;12:841-51 pubmed
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| Tofovic S, Zhang X, Jackson E, Dacic S, Petrusevska G. 2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension. Vascul Pharmacol. 2006;45:358-67 pubmed
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| Vargha R, Endemann M, Kratochwill K, Riesenhuber A, Wick N, Krachler A, et al. Ex vivo reversal of in vivo transdifferentiation in mesothelial cells grown from peritoneal dialysate effluents. Nephrol Dial Transplant. 2006;21:2943-7 pubmed
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| Shirai K, Saika S, Tanaka T, Okada Y, Flanders K, Ooshima A, et al. A new model of anterior subcapsular cataract: involvement of TGFbeta/Smad signaling. Mol Vis. 2006;12:681-91 pubmed
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| Saika S, Ikeda K, Yamanaka O, Flanders K, Okada Y, Miyamoto T, et al. Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healing. Am J Pathol. 2006;168:1848-60 pubmed
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| Carnevale K, Ouriel K, Gabriel Y, Clair D, Bena J, Silva M, et al. Biological coating for arterial stents: the next evolutionary change in stents. J Endovasc Ther. 2006;13:164-74 pubmed
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| Terada N, Ohno N, Murata S, Katoh R, Stallcup W, Ohno S. Immunohistochemical study of NG2 chondroitin sulfate proteoglycan expression in the small and large intestines. Histochem Cell Biol. 2006;126:483-90 pubmed
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| Giurea A, Ruger B, Hollemann D, Yanagida G, Kotz R, Fischer M. STRO-1+ mesenchymal precursor cells located in synovial surface projections of patients with osteoarthritis. Osteoarthritis Cartilage. 2006;14:938-43 pubmed
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| Cartwright J, Wareing M. An in vitro model of trophoblast invasion of spiral arteries. Methods Mol Med. 2006;122:59-74 pubmed
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| Karaboga R, Kilic O, Yaman O, Percinel S, Anafarta K. Long-term effect of experimental hypercholesterolemia on cavernosal tissues. Urology. 2006;67:431-4 pubmed
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| Yesim G, Gupse T, Zafer U, Ahmet A. Mesenchymal hamartoma of the liver in adulthood: immunohistochemical profiles, clinical and histopathological features in two patients. J Hepatobiliary Pancreat Surg. 2005;12:502-7 pubmed
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| Amoh Y, Li L, Campillo R, Kawahara K, Katsuoka K, Penman S, et al. Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves. Proc Natl Acad Sci U S A. 2005;102:17734-8 pubmed
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| Hemendinger R, Wang J, Malik S, Persinski R, Copeland J, Emerich D, et al. Sertoli cells improve survival of motor neurons in SOD1 transgenic mice, a model of amyotrophic lateral sclerosis. Exp Neurol. 2005;196:235-43 pubmed
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| Izuhara Y, Nangaku M, Inagi R, Tominaga N, Aizawa T, Kurokawa K, et al. Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering. J Am Soc Nephrol. 2005;16:3631-41 pubmed
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| Saglam E, Usubutun A, Kart C, Ayhan A, Kucukali T. Reactive nodular fibrous pseudotumor involving the pelvic and abdominal cavity: a case report and review of literature. Virchows Arch. 2005;447:879-82 pubmed
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| Park E, Shin S, Ma C, Kim Y, Kim S. meso-dihydroguaiaretic acid from Machilus thunbergii down-regulates TGF-beta1 gene expression in activated hepatic stellate cells via inhibition of AP-1 activity. Planta Med. 2005;71:393-8 pubmed
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| Saika S, Yamanaka O, Ikeda K, Kim Mitsuyama S, Flanders K, Yoo J, et al. Inhibition of p38MAP kinase suppresses fibrotic reaction of retinal pigment epithelial cells. Lab Invest. 2005;85:838-50 pubmed
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| Stonecypher M, Byer S, Grizzle W, Carroll S. Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors. Oncogene. 2005;24:5589-605 pubmed
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| Saika S, Ikeda K, Yamanaka O, Miyamoto T, Ohnishi Y, Sato M, et al. Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali. Am J Pathol. 2005;166:1405-18 pubmed
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| Saika S, Miyamoto T, Yamanaka O, Kato T, Ohnishi Y, Flanders K, et al. Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-kappaB, in treatment of corneal alkali burns in mice. Am J Pathol. 2005;166:1393-403 pubmed
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| Cristina C, Diaz Torga G, Baldi A, Gongora A, Rubinstein M, Low M, et al. Increased pituitary vascular endothelial growth factor-a in dopaminergic D2 receptor knockout female mice. Endocrinology. 2005;146:2952-62 pubmed
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| Uluoglu O, Akyurek N, Uner A, Coskun U, Ozdemir A, Gokcora N. Interdigitating dendritic cell tumor with breast and cervical lymph-node involvement: a case report and review of the literature. Virchows Arch. 2005;446:546-54 pubmed
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| Amoh Y, Li L, Katsuoka K, Penman S, Hoffman R. Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons. Proc Natl Acad Sci U S A. 2005;102:5530-4 pubmed
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| Shinde Patil V, Friedrich E, Wolley A, Gerszten R, Allport J, Weissleder R. Bone marrow-derived lin(-)c-kit(+)Sca-1+ stem cells do not contribute to vasculogenesis in Lewis lung carcinoma. Neoplasia. 2005;7:234-40 pubmed
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| Hays S, Ferrando R, Carter R, Wong H, Woodruff P. Structural changes to airway smooth muscle in cystic fibrosis. Thorax. 2005;60:226-8 pubmed
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| Kubo A, Chen V, Kennedy M, Zahradka E, Daley G, Keller G. The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiation. Blood. 2005;105:4590-7 pubmed
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| Saika S, Ikeda K, Yamanaka O, Flanders K, Nakajima Y, Miyamoto T, et al. Therapeutic effects of adenoviral gene transfer of bone morphogenic protein-7 on a corneal alkali injury model in mice. Lab Invest. 2005;85:474-86 pubmed
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| Herrero Fresneda I, Torras J, Vidal A, Lloberas N, Cruzado J, Grinyo J. Reduction of postischemic immune inflammatory response: an effective strategy for attenuating chronic allograft nephropathy. Transplantation. 2005;79:165-73 pubmed
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| Ara T, Tokoyoda K, Okamoto R, Koni P, Nagasawa T. The role of CXCL12 in the organ-specific process of artery formation. Blood. 2005;105:3155-61 pubmed
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| van Tuyl M, Groenman F, Kuliszewski M, Ridsdale R, Wang J, Tibboel D, et al. Overexpression of lunatic fringe does not affect epithelial cell differentiation in the developing mouse lung. Am J Physiol Lung Cell Mol Physiol. 2005;288:L672-82 pubmed
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Holloway S, Beck A, Shivakumar L, Shih J, Fleming J, Brekken R. Selective blockade of vascular endothelial growth factor receptor 2 with an antibody against tumor-derived vascular endothelial growth factor controls the growth of human pancreatic adenocarcinoma xenografts. Ann Surg Oncol. 2006;13:1145-55 pubmed
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Dagli M, Eryilmaz A, Acar A, Kulacoglu S, Akmansu H. Collagenous fibroma (desmoplastic fibroblastoma). Yonsei Med J. 2004;45:941-3 pubmed
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Bircan S, Candir O, Aydin S, Baspinar S, Bulbul M, Kapucuoglu N, et al. Synchronous primary adenocarcinoma and gastrointestinal stromal tumor in the stomach: a report of two cases. Turk J Gastroenterol. 2004;15:187-91 pubmed
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Park J, Choi S, Lee S, Min K, Yun S, Jeon H. Malignant gastrointestinal stromal tumor of the gallbladder. J Korean Med Sci. 2004;19:763-7 pubmed
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Schedin P, Mitrenga T, McDaniel S, Kaeck M. Mammary ECM composition and function are altered by reproductive state. Mol Carcinog. 2004;41:207-20 pubmed
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Bildirici K, Donmez T, Gürlek E. Inflammatory pseudotumor of the kidney. Int Urol Nephrol. 2004;36:141-3 pubmed
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Wei P, Lane P, Lane J, Padanilam B, Sansom S. Glomerular structural and functional changes in a high-fat diet mouse model of early-stage Type 2 diabetes. Diabetologia. 2004;47:1541-9 pubmed
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Saika S, Kono Saika S, Tanaka T, Yamanaka O, Ohnishi Y, Sato M, et al. Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice. Lab Invest. 2004;84:1245-58 pubmed
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Lai C, Tai M, Liang C, Lee H. Unusual uveal tract tumor: mesectodermal leiomyoma of the ciliary body. Pathol Int. 2004;54:337-42 pubmed
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Luo Y, Yu J, Shi Z, Wang L. Ginkgo biloba extract reverses CCl4-induced liver fibrosis in rats. World J Gastroenterol. 2004;10:1037-42 pubmed
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Jarrousse C, Lods N, Michel F, Bali J, Magous R. Cultured gastrointestinal smooth muscle cells: cell response to contractile agonists depends on their phenotypic state. Cell Tissue Res. 2004;316:221-32 pubmed
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Woodruff P, Dolganov G, Ferrando R, Donnelly S, Hays S, Solberg O, et al. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med. 2004;169:1001-6 pubmed
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Sato M, Muragaki Y, Saika S, Roberts A, Ooshima A. Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest. 2003;112:1486-94 pubmed
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Saika S, Miyamoto T, Ohnishi Y. Histology of anterior capsule opacification with a polyHEMA/HOHEXMA hydrophilic hydrogel intraocular lens compared to poly(methyl methacrylate), silicone, and acrylic lenses. J Cataract Refract Surg. 2003;29:1198-203 pubmed
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Saika S, Miyamoto T, Tanaka S, Tanaka T, Ishida I, Ohnishi Y, et al. Response of lens epithelial cells to injury: role of lumican in epithelial-mesenchymal transition. Invest Ophthalmol Vis Sci. 2003;44:2094-102 pubmed
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Yurugi Kobayashi T, Itoh H, Yamashita J, Yamahara K, Hirai H, Kobayashi T, et al. Effective contribution of transplanted vascular progenitor cells derived from embryonic stem cells to adult neovascularization in proper differentiation stage. Blood. 2003;101:2675-8 pubmed
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Bruneval P, Bariety J, Belair M, Mandet C, Heudes D, Nicoletti A. Mesangial expansion associated with glomerular endothelial cell activation and macrophage recruitment is developing in hyperlipidaemic apoE null mice. Nephrol Dial Transplant. 2002;17:2099-107 pubmed
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Canter H, Vargel I, Mavlll M, Gokoz A, Erk Y. Tissue response to N-butyl-2-cyanoacrylate after percutaneous injection into cutaneous vascular lesions. Ann Plast Surg. 2002;49:520-6 pubmed
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Kielman M, Rindapää M, Gaspar C, van Poppel N, Breukel C, van Leeuwen S, et al. Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling. Nat Genet. 2002;32:594-605 pubmed
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Kranenburg A, de Boer W, van Krieken J, Mooi W, Walters J, Saxena P, et al. Enhanced expression of fibroblast growth factors and receptor FGFR-1 during vascular remodeling in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2002;27:517-25 pubmed
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Cinel L, Dusmez D, Nabaei S, Taner D, Pata O. Two intraligamentary lipomatous tumors with immunohistochemical features. Acta Obstet Gynecol Scand. 2002;81:786-7 pubmed
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Li Y, Pan Z, Ji Y, Peng T, Archard L, Zhang H. Enterovirus replication in valvular tissue from patients with chronic rheumatic heart disease. Eur Heart J. 2002;23:567-73 pubmed
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Szeto W, Jiang W, Tice D, Rubinfeld B, Hollingshead P, Fong S, et al. Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid. Cancer Res. 2001;61:4197-205 pubmed
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Lavaud S, Poirier B, Mandet C, Belair M, Irinopoulou T, Heudes D, et al. Inflammation is probably not a prerequisite for renal interstitial fibrosis in normoglycemic obese rats. Am J Physiol Renal Physiol. 2001;280:F683-94 pubmed
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Suzuki D, Miyata T, Nangaku M, Takano H, Saotome N, Toyoda M, et al. Expression of megsin mRNA, a novel mesangium-predominant gene, in the renal tissues of various glomerular diseases. J Am Soc Nephrol. 1999;10:2606-13 pubmed
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图像
图像 1 :
Formalin-fixed, paraffin-embedded human leiomyoma stained with Smooth Muscle Actin antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of smooth muscle cells.
产品信息
产品类型 :
抗体
产品名称 :
Alpha-Smooth Muscle Actin Monoclonal Antibody (1A4 (asm-1)), Biotin
目录# :
MA5-11544
规格 :
500微升
定价 :
美国446
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Bovine, Chicken, Human, Mouse, Non-human primate, Rabbit, Rat
应用 :
Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 1:800, Western Blot: 1:100-1:500
物种 :
Bovine, Chicken, Human, Mouse, Non-human primate, Rabbit, Rat
克隆 :
1A4 (asm-1)
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Smooth Muscle Actin belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actin being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. In particular, smooth muscle actin is an alpha actin that is found in skeletal muscle. Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton. Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis. Smooth muscle actin is found on smooth muscle vessel walls, gut wall, myometrium, myoepithelial cells in breast and salivary glands. Defects in the smooth muscle actin gene cause aortic aneurysm familial thoracic type 6. Actin isoforms differ slightly in their N-terminus and the sequences of each are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown that smooth muscle actin appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases. Multiple alternatively spliced variants of smooth muscle actin have been identified.
免疫原 :
N-terminal decapeptide of alpha-smooth muscle isoform of actin; acetylated at the N-terminus
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 1:800, Western Blot: 1:100-1:500
别名 :
0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; ASMA; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg
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赛默飞世尔