产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
粘着斑蛋白单克隆抗体(VLN01)
目录 :
MA5-11690
规格 :
500微升
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
VLN01
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 8
出版应用/物种/样本/稀释参考文献
  • 免疫沉淀; 小鼠; 图 3a
  • 免疫沉淀; 人类; 图 3c
Cheng J, Kyle J, Lang D, Wiedmeyer B, Guo J, Yin K, et al. An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population. J Am Heart Assoc. 2017;6: pubmed 出版商
  • 免疫沉淀; 小鼠; 图 4a
Cheng J, Kyle J, Wiedmeyer B, Lang D, Vaidyanathan R, Makielski J. Vinculin variant M94I identified in sudden unexplained nocturnal death syndrome decreases cardiac sodium current. Sci Rep. 2017;7:42953 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Currier M, Lee S, Stobart C, Hotard A, Villenave R, Meng J, et al. EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression. PLoS Pathog. 2016;12:e1005622 pubmed 出版商
  • 免疫组化; 人类; 1:50
Yang H, Chen J, Zhang W, Ding Y. Focal adhesion plaque associated cytoskeletons are involved in the invasion and metastasis of human colorectal carcinoma. Cancer Invest. 2010;28:127-34 pubmed 出版商
Lim K, Han Z, Jeon H, Kach J, Jing E, Weyn Vanhentenryck S, et al. Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression. Nat Commun. 2020;11:3501 pubmed 出版商
Farini A, Villa C, Di Silvestre D, Bella P, Tripodi L, Rossi R, et al. PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy. Front Physiol. 2020;11:403 pubmed 出版商
Watts K, Spiteri M. Connective tissue growth factor expression and induction by transforming growth factor-beta is abrogated by simvastatin via a Rho signaling mechanism. Am J Physiol Lung Cell Mol Physiol. 2004;287:L1323-32 pubmed
Willey C, Balasubramanian S, Rodríguez Rosas M, Ross R, Kuppuswamy D. Focal complex formation in adult cardiomyocytes is accompanied by the activation of beta3 integrin and c-Src. J Mol Cell Cardiol. 2003;35:671-83 pubmed
图像
图像 1 :
赛默飞世尔 MA5-11690 图像 1
图像 2 :
赛默飞世尔 MA5-11690 图像 2
产品信息
产品类型 :
抗体
产品名称 :
粘着斑蛋白单克隆抗体(VLN01)
目录# :
MA5-11690
规格 :
500微升
价格 :
美国425.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
Human, Mouse, Non-human primate
应用 :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL
物种 :
Human, Mouse, Non-human primate
克隆 :
VLN01
抗体亚型 :
IgG1
储存 :
4° C
描述 :
Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions. It functions as one of several interacting proteins involved in anchoring F-actin to the membrane. It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques. In the assembly of adhesion plaques, the beta subunit of integrin binds to talin. Talin binds to vinculin that interacts with alpha-actinin and possibly with itself. Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system. Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.
免疫原 :
Semi-purified vinculin
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL
别名 :
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国