产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Mast Cell Chymase Monoclonal Antibody (CC1)
目录 :
MA5-11717
规格 :
500微升
价格 :
美国418
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CC1
反应物种 :
人类, 大鼠, 犬
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
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文章摘录数: 12
出版应用/物种/样本/稀释 | 参考文献 |
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| Popescu L, Gherghiceanu M, Hinescu M, Cretoiu D, Ceafalan L, Regalia T, et al. Insights into the interstitium of ventricular myocardium: interstitial Cajal-like cells (ICLC). J Cell Mol Med. 2006;10:429-58 pubmed
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| Fukiwake N, Moroi Y, Imafuku S, Masuda T, Kokuba H, Furue M, et al. Anti-CXCR3 staining is useful for detecting human cutaneous and mucosal mast cells. J Dermatol. 2006;33:326-30 pubmed
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| Fernandez N, West K, Jackson M, Kidney B. Immunohistochemical and histochemical stains for differentiating canine cutaneous round cell tumors. Vet Pathol. 2005;42:437-45 pubmed
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| Edwards S, Cruz A, Donnelly S, Dazin P, Schulman E, Jones K, et al. c-Kit immunophenotyping and metalloproteinase expression profiles of mast cells in interstitial lung diseases. J Pathol. 2005;206:279-90 pubmed
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图像
图像 1 :
Formalin-fixed, paraffin-embedded human tonsil stained with Mast Cell Chymase antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of mast cells.
产品信息
产品类型 :
抗体
产品名称 :
Mast Cell Chymase Monoclonal Antibody (CC1)
目录# :
MA5-11717
规格 :
500微升
定价 :
美国418
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunohistochemistry (Paraffin): 1:2,000, Western Blot: Assay-dependent
物种 :
人类
克隆 :
CC1
抗体亚型 :
IgG1
储存 :
4° C
描述 :
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11. 2 in a cluster of genes encoding other proteases.
免疫原 :
Purified human skin chymase
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:2,000, Western Blot: Assay-dependent
别名 :
alpha-chymase; Chymase; chymase 1; chymase 1 preproprotein transcript E; chymase 1 preproprotein transcript I; chymase 1, mast cell; chymase, heart; chymase, mast cell; CMA1; CYH; CYM; mast cell; Mast cell chymase 1; mast cell protease 3; Mast cell protease 5; mast cell protease I; Mast cell protease III; MCP3P; Mcp5; Mcp-5; Mcpt3; Mcpt5; MCT1; mMCP-5; rMCP-3; rMCP-5; rMCP-III
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公司信息
赛默飞世尔