产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
纤连蛋白单克隆抗体(FBN11)
目录 :
MA5-11981
规格 :
500微升
价格 :
美国420
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
FBN11
反应物种 :
人类, 小鼠, 大鼠, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 5d
Xu J, Zhu S, Heng B, Dissanayaka W, Zhang C. TGF-?1-induced differentiation of SHED into functional smooth muscle cells. Stem Cell Res Ther. 2017;8:10 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1f
Gong T, Heng B, Xu J, Zhu S, Yuan C, Lo E, et al. Decellularized extracellular matrix of human umbilical vein endothelial cells promotes endothelial differentiation of stem cells from exfoliated deciduous teeth. J Biomed Mater Res A. 2017;105:1083-1093 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2a
Choi S, Piao Z, Jin L, Kim J, Kim G, Ryu Y, et al. Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling. PLoS ONE. 2016;11:e0167340 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Choi S, Kee H, Kurz T, Hansen F, Ryu Y, Kim G, et al. Class I HDACs specifically regulate E-cadherin expression in human renal epithelial cells. J Cell Mol Med. 2016;20:2289-2298 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Heng B, Zhu S, Xu J, Yuan C, Gong T, Zhang C. Effects of decellularized matrices derived from periodontal ligament stem cells and SHED on the adhesion, proliferation and osteogenic differentiation of human dental pulp stem cells in vitro. Tissue Cell. 2016;48:133-43 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:500
Kokubo M, Sato M, Yamato M, Mitani G, Kutsuna T, Ebihara G, et al. Characterization of chondrocyte sheets prepared using a co-culture method with temperature-responsive culture inserts. J Tissue Eng Regen Med. 2016;10:486-95 pubmed 出版商
  • 免疫组化; 猕猴
Klatt N, Canary L, Sun X, Vinton C, Funderburg N, Morcock D, et al. Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques. J Clin Invest. 2013;123:903-7 pubmed 出版商
  • 免疫组化; 小鼠
Bravo Nuevo A, O Donnell R, Rosendahl A, Chung J, Benjamin L, Odaka C. RhoB deficiency in thymic medullary epithelium leads to early thymic atrophy. Int Immunol. 2011;23:593-600 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200
Liu K, Li Y, Wang H, Jiang X, Zhao Y, Sun D, et al. The immunohistochemical characterization of human fetal olfactory bulb and olfactory ensheathing cells in culture as a source for clinical CNS restoration. Anat Rec (Hoboken). 2010;293:359-69 pubmed 出版商
  • 免疫组化; 人类
Rnjak J, Li Z, Maitz P, Wise S, Weiss A. Primary human dermal fibroblast interactions with open weave three-dimensional scaffolds prepared from synthetic human elastin. Biomaterials. 2009;30:6469-77 pubmed 出版商
  • 免疫组化; 人类; 1:500
Mitani G, Sato M, Lee J, Kaneshiro N, Ishihara M, Ota N, et al. The properties of bioengineered chondrocyte sheets for cartilage regeneration. BMC Biotechnol. 2009;9:17 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Liao P, Li G, Yu D, Yong T, Wang J, Wang J, et al. Molecular alteration of Ca(v)1.2 calcium channel in chronic myocardial infarction. Pflugers Arch. 2009;458:701-11 pubmed 出版商
  • 免疫组化; 人类
Andersen T, Sondergaard T, Skorzynska K, Dagnaes Hansen F, Plesner T, Hauge E, et al. A physical mechanism for coupling bone resorption and formation in adult human bone. Am J Pathol. 2009;174:239-47 pubmed 出版商
  • 免疫细胞化学; 猕猴; 20 ug/ml
Cao W, Mah K, Carroll R, Slayden O, Brenner R. Progesterone withdrawal up-regulates fibronectin and integrins during menstruation and repair in the rhesus macaque endometrium. Hum Reprod. 2007;22:3223-31 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Guo Z, Yan Z, Bai L, Zhang M, Jiang Z. Flow shear stress affects macromolecular accumulation through modulation of internal elastic lamina fenestrae. Clin Biomech (Bristol, Avon). 2008;23 Suppl 1:S104-11 pubmed
  • 免疫组化; 大鼠; 1:100
Shynlova O, Williams S, Draper H, White B, MacPhee D, Lye S. Uterine stretch regulates temporal and spatial expression of fibronectin protein and its alpha 5 integrin receptor in myometrium of unilaterally pregnant rats. Biol Reprod. 2007;77:880-8 pubmed
  • 免疫组化; 大鼠; 1:100
  • 免疫印迹; 大鼠; 1:100
Cui C, Chen A, Jiang Z, Wu Q, Lin J, Wen H, et al. Inhibition of NAD(P)H oxidase reduces fibronectin expression in stroke-prone renovascular hypertensive rat brain. Clin Exp Pharmacol Physiol. 2007;34:304-9 pubmed
  • 免疫组化; 大鼠
Guven A, Yavuz O, Cam M, Ercan F, Bukan N, Comunoglu C. Melatonin protects against epirubicin-induced cardiotoxicity. Acta Histochem. 2007;109:52-60 pubmed
Zhao T, Kee H, Kee S, Jeong M. Hdac8 Inhibitor Alleviates Transverse Aortic Constriction-Induced Heart Failure in Mice by Downregulating Ace1. Oxid Med Cell Longev. 2022;2022:6227330 pubmed 出版商
Niemann S, Nguyen M, Eble J, Chasan A, Mrakovcic M, B xf6 ttcher R, et al. More Is Not Always Better-the Double-Headed Role of Fibronectin in Staphylococcus aureus Host Cell Invasion. MBio. 2021;12:e0106221 pubmed 出版商
Ji S, Gumina D, McPeak K, Moldovan R, Post M, Su E. Human placental villous stromal extracellular matrix regulates fetoplacental angiogenesis in severe fetal growth restriction. Clin Sci (Lond). 2021;135:1127-1143 pubmed 出版商
Zhou H, Li L, Xie W, Wu L, Lin Y, He X. TAGLN and High-mobility Group AT-Hook 2 (HMGA2) Complex Regulates TGF-β-induced Colorectal Cancer Metastasis. Onco Targets Ther. 2020;13:10489-10498 pubmed 出版商
Li T, Peng R, Wang F, Hua L, Liu S, Han Z, et al. Lysophosphatidic acid promotes thrombus stability by inducing rapid formation of neutrophil extracellular traps: A new mechanism of thrombosis. J Thromb Haemost. 2020;18:1952-1964 pubmed 出版商
Berg H, Ju Z, Myrvold M, Fasmer K, Halle M, Hoivik E, et al. Development of prediction models for lymph node metastasis in endometrioid endometrial carcinoma. Br J Cancer. 2020;122:1014-1022 pubmed 出版商
Barrenas F, Raehtz K, Xu C, Law L, Green R, Silvestri G, et al. Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control. Nat Commun. 2019;10:5101 pubmed 出版商
Hodson N, Patel S, Richardson S, Hoyland J, Gilbert H. Degenerate intervertebral disc-like pH induces a catabolic mechanoresponse in human nucleus pulposus cells. JOR Spine. 2018;1:e1004 pubmed 出版商
Majumder S, Amatya N, Revu S, Jawale C, Wu D, Rittenhouse N, et al. IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival. Nat Immunol. 2019;20:534-545 pubmed 出版商
Tseng C, Lai Y, Kuo T, Su J, Sung P, Feng C, et al. Rhodoptilometrin, a Crinoid-Derived Anthraquinone, Induces Cell Regeneration by Promoting Wound Healing and Oxidative Phosphorylation in Human Gingival Fibroblast Cells. Mar Drugs. 2019;17: pubmed 出版商
Mi J, Hooker E, Balog S, Zeng H, Johnson D, He Y, et al. Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate. J Biol Chem. 2018;293:20123-20136 pubmed 出版商
Ryu Y, Jin L, Kee H, Piao Z, Cho J, Kim G, et al. Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity. Sci Rep. 2016;6:34790 pubmed 出版商
Menon S, Kakkar N, Radotra B. Expression of laminin and fibronectin in renal dysplasia. Pediatr Dev Pathol. 2004;7:568-76 pubmed
Plante E, Gaudreau M, Lachance D, Drolet M, Roussel E, Gauthier C, et al. Angiotensin-converting enzyme inhibitor captopril prevents volume overload cardiomyopathy in experimental chronic aortic valve regurgitation. Can J Physiol Pharmacol. 2004;82:191-9 pubmed
Berry S, Howard R, Akers R. Mammary localization and abundance of laminin, fibronectin, and collagen IV proteins in prepubertal heifers. J Dairy Sci. 2003;86:2864-74 pubmed
图像
图像 1 :
赛默飞世尔 MA5-11981 图像 1
Formalin-fixed, paraffin-embedded human kidney stained with Fibronectin antibody1 using peroxidase-conjugate and AEC chromogen. Note staining of tubular basement membranes, mesangial cells and matrix.
图像 2 :
赛默飞世尔 MA5-11981 图像 2
Formalin-fixed, paraffin-embedded human kidney stained with Fibronectin antibody1 using peroxidase-conjugate and AEC chromogen. Note staining of tubular basement membranes, mesangial cells and matrix.
图像 3 :
赛默飞世尔 MA5-11981 图像 3
产品信息
产品类型 :
抗体
产品名称 :
纤连蛋白单克隆抗体(FBN11)
目录# :
MA5-11981
规格 :
500微升
定价 :
美国420
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500-1:5,000
物种 :
人类, 小鼠, 大鼠
克隆 :
FBN11
抗体亚型 :
IgG1
储存 :
4° C
描述 :
Fibronectin is a disulfide-bonded dimer with a molecular weight range of 230-250 kDa. In the extracellular matrix of several connective tissues and vessels, fibronectin is present as an insoluble protein that is extensively cross-linked by interchain disulfide bonds forming high molecular mass polymers. Fibronectin is most abundant during embryonic development and tissue remodeling. Fibronectin is also present at high concentrations as a soluble plasma protein. Fibronectin is organized as a linear series of repeating modules which form domains for interaction with fibronectin itself, other matrix components (e.g. collagen and heparin) and receptors on cells (e.g. integrins). Fibronectin is present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. Fibronectin has been implicated in carcinoma development in lung cancer. Further, Fibronectin expression is increased especially in non-small cell lung carcinoma. The adhesion of lung carcinoma cells to Fibronectin enhances tumorgenecity and confers resistance to apoptosis induced by standard chemotherapeutic agents. The gene encoding Fibronectin has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some Fibronectin variants has not been determined.
免疫原 :
重组纤连蛋白蛋白
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500-1:5,000
别名 :
Anastellin; CIG; Cold insoluble globulin (CIG); Cold-insoluble globulin; cumulus cell-specific fibronectin 1 transcript; DKFZp686F10164; DKFZp686H0342; DKFZp686I1370; DKFZp686O13149; E330027I09; ED-B; embryo-specific fibronectin 1 transcript; ferritin L subunit; ferritin L-chain; FIBNEC; fibronectin; fibronectin 1; fibronectin ED-A- region; fibronectin ED-B+ region; fibronectin variable region; FINC; FN; FN1; fn-1; FNZ; GFND; GFND2; LETS; LOW QUALITY PROTEIN: fibronectin; Migration stimulating factor (MSF); migration-stimulating factor; MSF; Ugl-Y1; Ugl-Y2; Ugl-Y3
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国