产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GFAP单克隆抗体(ASTRO6)
目录 :
MA5-12023
规格 :
500µL
价格 :
美国275.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
ASTRO6
反应物种 :
Epinephelus, 人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 36
出版应用/物种/样品/稀释参考文献
  • 免疫细胞化学; 小鼠; 图 s1b
Zhao T, Hong Y, Yin P, Li S, Li X. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proc Natl Acad Sci U S A. 2017;114:E7803-E7811 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:500; 图 5e
Liddelow S, Guttenplan K, Clarke L, Bennett F, Bohlen C, Schirmer L, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017;541:481-487 pubmed 出版商
  • 免疫细胞化学; Epinephelus; 图 1a
Chiang Y, Wu Y, Chi S. Interleukin-1β secreted from betanodavirus-infected microglia caused the death of neurons in giant grouper brains. Dev Comp Immunol. 2017;70:19-26 pubmed 出版商
  • 免疫组化; 小鼠; 1:2000; 图 2C
Liu S, Li Q, Zhang M, Mao Ying Q, Hu L, Wu G, et al. Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling. Sci Rep. 2016;6:28956 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4
Hochmeister S, Engel O, Adzemovic M, Pekar T, Kendlbacher P, Zeitelhofer M, et al. Lipocalin-2 as an Infection-Related Biomarker to Predict Clinical Outcome in Ischemic Stroke. PLoS ONE. 2016;11:e0154797 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 4
Yang Y, Fang J, Li D, Wang L, Ji N, Zhang J. Recurrent intracranial neurenteric cyst with malignant transformation: A case report and literature review. Oncol Lett. 2016;11:3395-3402 pubmed
  • 免疫组化-冰冻切片; 小鼠; 1:2000; 图 3
  • 免疫印迹; 小鼠; 1:5000; 图 7
Liu S, Mi W, Li Q, Zhang M, Han P, Hu S, et al. Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII-CREB and Astroglial JAK2-STAT3 Cascades in Mice. Anesthesiology. 2015;123:1154-69 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5
Li W, Garringer H, GOODWIN C, Richine B, Acton A, Vanduyn N, et al. Systemic and cerebral iron homeostasis in ferritin knock-out mice. PLoS ONE. 2015;10:e0117435 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
Kamel Ismail Z, Morcos M, Eldin Mohammad M, Gamal Aboulkhair A. Enhancement of Neural Stem Cells after Induction of Depression in Male Albino Rats (A histological & Immunohistochemical Study). Int J Stem Cells. 2014;7:70-8 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:1000
  • 免疫组化; 大鼠
Oh J, Daniels G, Chiou L, Ye E, Jeong Y, Sakaguchi D. Multipotent adult hippocampal progenitor cells maintained as neurospheres favor differentiation toward glial lineages. Biotechnol J. 2014;9:921-33 pubmed 出版商
  • 免疫组化; 大鼠; 1:500
Yang L, Yue N, Zhu X, Han Q, Li B, Liu Q, et al. Electroacupuncture promotes proliferation of amplifying neural progenitors and preserves quiescent neural progenitors from apoptosis to alleviate depressive-like and anxiety-like behaviours. Evid Based Complement Alternat Med. 2014;2014:872568 pubmed 出版商
  • 免疫组化; 大鼠; 1:200
Kitic M, Wimmer I, Adzemovic M, K gl N, Rudel A, Lassmann H, et al. Thymic stromal lymphopoietin is expressed in the intact central nervous system and upregulated in the myelin-degenerative central nervous system. Glia. 2014;62:1066-74 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫组化; 人类
  • 免疫印迹; 人类
Yan S, Wang C, Wei W, Gaertig M, Lai L, Li S, et al. TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain. Hum Mol Genet. 2014;23:2678-93 pubmed 出版商
  • 免疫组化; 人类
Pohl M, Kawakami N, Kitic M, Bauer J, Martins R, Fischer M, et al. T cell-activation in neuromyelitis optica lesions plays a role in their formation. Acta Neuropathol Commun. 2013;1:85 pubmed 出版商
  • 免疫组化; 大鼠; 1:1000
Li Q, Tian Y, Wang Z, Liu S, Mi W, Ma H, et al. Involvement of the spinal NALP1 inflammasome in neuropathic pain and aspirin-triggered-15-epi-lipoxin A4 induced analgesia. Neuroscience. 2013;254:230-40 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:400
Qiu J, Zhang C, Lv Y, Zhang Y, Zhu C, Wang X, et al. Cdh1 inhibits reactive astrocyte proliferation after oxygen-glucose deprivation and reperfusion. Neurochem Int. 2013;63:87-92 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Xue H, Zhang X, Liu J, Song Y, Liu T, Chen D. NDGA reduces secondary damage after spinal cord injury in rats via anti-inflammatory effects. Brain Res. 2013;1516:83-92 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Yang M, Dibas A, Tyan Y. Changes in retinal aquaporin-9 (AQP9) expression in glaucoma. Biosci Rep. 2013;33: pubmed 出版商
  • 免疫组化; 大鼠; 1:500
Choi Y, Jun I, Kim S, Park J. Intrathecal lamotrigine attenuates mechanical allodynia and suppresses microglial and astrocytic activation in a rat model of spinal nerve ligation. Yonsei Med J. 2013;54:321-9 pubmed 出版商
  • 免疫组化; 小鼠; 1:500
  • 免疫印迹; 小鼠; 1:1000
Park Y, Lee W, Bokara K, Seo S, Park S, Kim J, et al. The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells. PLoS ONE. 2013;8:e53911 pubmed 出版商
  • 免疫组化; 大鼠; 1:200
Hebron M, Algarzae N, Lonskaya I, Moussa C. Fractalkine signaling and Tau hyper-phosphorylation are associated with autophagic alterations in lentiviral Tau and A?1-42 gene transfer models. Exp Neurol. 2014;251:127-38 pubmed 出版商
  • 免疫组化; 小鼠; 1:5000
Shen W, Fruttiger M, Zhu L, Chung S, Barnett N, Kirk J, et al. Conditional Müllercell ablation causes independent neuronal and vascular pathologies in a novel transgenic model. J Neurosci. 2012;32:15715-27 pubmed 出版商
  • 免疫组化; 大鼠; 1:200
Tan Y, Li K, Chen X, Cao Y, Light A, Fu K. Activation of Src family kinases in spinal microglia contributes to formalin-induced persistent pain state through p38 pathway. J Pain. 2012;13:1008-15 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200
Wu X, Liu Y, Chen X, Sun Q, Tang R, Wang W, et al. Involvement of TREK-1 activity in astrocyte function and neuroprotection under simulated ischemia conditions. J Mol Neurosci. 2013;49:499-506 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Xue H, Zhang X, Liu J, Song Y, Li Y, Chen D. Development of a chemically extracted acellular muscle scaffold seeded with amniotic epithelial cells to promote spinal cord repair. J Biomed Mater Res A. 2013;101:145-56 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Duran Vilaregut J, Manich G, del Valle J, Camins A, Pallas M, Vilaplana J, et al. Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3? in the striatum of rats treated with 3-nitropropionic acid. J Neurosci Res. 2012;90:1803-13 pubmed 出版商
  • 免疫组化; 猪; 1:200
Wang H, Wang X, Guo Q. The correlation between DTI parameters and levels of AQP-4 in the early phases of cerebral edema after hypoxic-ischemic/reperfusion injury in piglets. Pediatr Radiol. 2012;42:992-9 pubmed 出版商
  • 免疫组化; 大鼠; 1:200
Tomita K, Madura T, Mantovani C, Terenghi G. Differentiated adipose-derived stem cells promote myelination and enhance functional recovery in a rat model of chronic denervation. J Neurosci Res. 2012;90:1392-402 pubmed 出版商
  • 免疫组化; 小鼠; 1:400
Cho S, Kim J, Simons D, Song J, Le J, Swindell E, et al. Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis. Hum Mol Genet. 2012;21:2663-76 pubmed 出版商
  • 免疫组化; 人类; 1:200
Fischer M, Sharma R, Lim J, Haider L, Frischer J, Drexhage J, et al. NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury. Brain. 2012;135:886-99 pubmed 出版商
  • 免疫组化; 人类; 1:1600
Miller A, Baitchman E, Masek Hammerman K. Multiple endocardial neurofibromas in a rosy-billed pochard (Netta peposaca). J Vet Diagn Invest. 2012;24:408-11 pubmed 出版商
  • 免疫组化; 人类; 1:100
Begum A, Kim Y, Lin Q, Yun Z. DLK1, delta-like 1 homolog (Drosophila), regulates tumor cell differentiation in vivo. Cancer Lett. 2012;318:26-33 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:300
  • 免疫组化; 大鼠; 1:200
Wang M, Song J, Xiao W, Yang L, Yuan J, Wang W, et al. Changes in lipid-sensitive two-pore domain potassium channel TREK-1 expression and its involvement in astrogliosis following cerebral ischemia in rats. J Mol Neurosci. 2012;46:384-92 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200
Nho Y, Kim J, Khang D, Webster T, Lee J. Adsorption of mesenchymal stem cells and cortical neural stem cells on carbon nanotube/polycarbonate urethane. Nanomedicine (Lond). 2010;5:409-17 pubmed 出版商
  • 免疫组化; 人类; 1:50
Schwab N, Bien C, Waschbisch A, Becker A, Vince G, Dornmair K, et al. CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery. Brain. 2009;132:1236-46 pubmed 出版商
  • 免疫组化; 猪
Katchman H, Tal O, Eventov Friedman S, Shezen E, Aronovich A, Tchorsh D, et al. Embryonic porcine liver as a source for transplantation: advantage of intact liver implants over isolated hepatoblasts in overcoming homeostatic inhibition by the quiescent host liver. Stem Cells. 2008;26:1347-55 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-12023 图像 1
Formalin-fixed, paraffin-embedded human brain stained with GFAP antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of astrocytes.
图像 2 :
赛默飞世尔 MA5-12023 图像 2
产品信息
产品类型 :
抗体
产品名称 :
GFAP单克隆抗体(ASTRO6)
目录# :
MA5-12023
规格 :
500µL
价格 :
美国275.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
鸡, 人类, 猪, 大鼠
应用 :
Immunocytochemistry: 1:20-1:200, Immunofluorescence: 1:20-1:200, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1-2 µg/mL
物种 :
鸡, 人类, 猪, 大鼠
克隆 :
ASTRO6
抗体亚型 :
IgG1
储存 :
4° C
描述 :
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily, and specifically, expressed in astrocytes and certain astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
免疫原 :
胶质纤维酸性蛋白
格式 :
Liquid
应用w/稀释 :
Immunocytochemistry: 1:20-1:200, Immunofluorescence: 1:20-1:200, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1-2 µg/mL
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
www.thermo.com.cn
1084193588
公司总部: 美国