产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(NCH-38)
目录 :
MA5-12547
规格 :
500微升
价格 :
美国440.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
NCH-38
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 4f
Stock K, Borrink R, Mikesch J, Hansmeier A, Rehkämper J, Trautmann M, et al. Overexpression and Tyr421-phosphorylation of cortactin is induced by three-dimensional spheroid culturing and contributes to migration and invasion of pancreatic ductal adenocarcinoma (PDAC) cells. Cancer Cell Int. 2019;19:77 pubmed 出版商
  • 免疫印迹; 人类
Yan H, Xu J, Fang L, Qiu Y, Lin X, Huang H, et al. Ectopic expression of the WWOX gene suppresses stemness of human ovarian cancer stem cells. Oncol Lett. 2015;9:1614-1620 pubmed
  • 免疫组化; 人类; 1:10
Marian C, Boilă A, Soanca D, Malau M, Podeanu D, Resetkova E, et al. Malignant transformation of adenomyoepithelioma of the breast by a monophasic population: a report of two cases and review of literature. APMIS. 2013;121:272-9 pubmed 出版商
  • 免疫组化; 人类; 1:25
Ruckert F, Aust D, Böhme I, Werner K, Brandt A, Diamandis E, et al. Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method. J Surg Res. 2012;172:29-39 pubmed 出版商
  • 免疫组化; 大鼠
Atalay B, Bavbek M, Ozen O, Nacar A, Gulsen S, Yigitkanli K, et al. Nogo-A inhibitory peptide (NEP1-40) increases pan-cadherin expression following mild cortical contusion injury in rats. Turk Neurosurg. 2008;18:356-65 pubmed
  • 免疫组化; 人类
Gurzu S, Jung I, Prantner I, Ember I, Pávai Z, Mezei T. The expression of cytoskeleton regulatory protein Mena in colorectal lesions. Rom J Morphol Embryol. 2008;49:345-9 pubmed
  • 免疫组化; 人类
Fadare O, Wang S, Hileeto D. The expression of cytokeratin 5/6 in invasive lobular carcinoma of the breast: evidence of a basal-like subset?. Hum Pathol. 2008;39:331-6 pubmed 出版商
  • 免疫细胞化学; 人类
Li N, Broad S, Lu Y, Yang J, Watson R, Hagemann T, et al. Human ovarian surface epithelial cells immortalized with hTERT maintain functional pRb and p53 expression. Cell Prolif. 2007;40:780-94 pubmed
  • 免疫组化; 人类; 1:500
Skalova A, Ryska A, Kajo K, Di Palma S, Kinkor Z, Michal M. Cystic hypersecretory carcinoma: rare and poorly recognized variant of intraductal carcinoma of the breast. Report of five cases. Histopathology. 2005;46:43-9 pubmed
Coati I, Lotz G, Fanelli G, Brignola S, Lanza C, Cappellesso R, et al. Claudin-18 expression in oesophagogastric adenocarcinomas: a tissue microarray study of 523 molecularly profiled cases. Br J Cancer. 2019;: pubmed 出版商
Rasiah P, Maddala R, Bennett V, Rao P. Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth. Dev Biol. 2019;446:119-131 pubmed 出版商
Petrova E, Scholz A, Paul J, Sturz A, Haike K, Siegel F, et al. Acetyl-CoA carboxylase inhibitors attenuate WNT and Hedgehog signaling and suppress pancreatic tumor growth. Oncotarget. 2017;8:48660-48670 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-12547 图像 1
Formalin-fixed, paraffin-embedded human breast carcinoma stained with E-Cadherin antibody using peroxidase-conjugate and AEC chromogen. Note membrane staining of tumor cells.
产品信息
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(NCH-38)
目录# :
MA5-12547
规格 :
500微升
价格 :
美国440.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:5-1:10, Western Blot: 1:250
物种 :
人类, 小鼠
克隆 :
NCH-38
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
免疫原 :
E钙粘蛋白和谷胱甘肽S-转移酶重组蛋白
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:5-1:10, Western Blot: 1:250
别名 :
AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-Cadherin phospho; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; phospho cadherin 1; phospho E-Cadherin; phospho LCAM; phospho S838; phospho UVO; S840; S840 E-Cadherin; Ser840; Ser840 E-Cadherin; Um; UVO; Uvomorulin
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国