产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Cdc7单克隆抗体(DCS-341)
目录 :
MA5-12589
规格 :
500微升
价格 :
美国455.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DCS-341
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 7
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:20
  • 免疫印迹; 人类
Cheng A, Jiang S, Fan C, Lo Y, Kuo C, Chen C, et al. Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents. Cancer Lett. 2013;337:218-25 pubmed 出版商
  • 免疫沉淀; 人类; 图 2
  • 免疫印迹; 人类; 图 5
Gardner L, Malik R, Shimizu Y, Mullins N, ElShamy W. Geminin overexpression prevents the completion of topoisomerase II? chromosome decatenation, leading to aneuploidy in human mammary epithelial cells. Breast Cancer Res. 2011;13:R53 pubmed 出版商
  • 免疫印迹; 人类
Hughes S, Jenkins V, Dar M, Engelman A, Cherepanov P. Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activity. J Biol Chem. 2010;285:541-54 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Charych D, Coyne M, Yabannavar A, Narberes J, Chow S, Wallroth M, et al. Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells. J Cell Biochem. 2008;104:1075-86 pubmed 出版商
  • 免疫印迹; 人类
Nakuci E, Xu M, Pujana M, Valls J, ElShamy W. Geminin is bound to chromatin in G2/M phase to promote proper cytokinesis. Int J Biochem Cell Biol. 2006;38:1207-20 pubmed
  • 免疫印迹; 人类
Montagnoli A, Valsasina B, Brotherton D, Troiani S, Rainoldi S, Tenca P, et al. Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. J Biol Chem. 2006;281:10281-90 pubmed
Lee A, Chiba T, Truong L, Cheng A, Do J, Cho M, et al. Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint. J Biol Chem. 2012;287:2531-43 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-12589 图像 1
Formalin-fixed, paraffin-embedded human tonsil stained with CDC 7 antibody using UltraVision LP kit and AEC chromogen. Note nuclear staining of lymphocytes.
产品信息
产品类型 :
抗体
产品名称 :
Cdc7单克隆抗体(DCS-341)
目录# :
MA5-12589
规格 :
500微升
价格 :
美国455.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunohistochemistry (Paraffin): 1:25, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
物种 :
人类
克隆 :
DCS-341
抗体亚型 :
IgG1
储存 :
4° C
描述 :
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
免疫原 :
谷胱甘肽S-转移酶融合蛋白全长CDC7
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:25, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
别名 :
AI597260; Cdc7; CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1; Cdc7 Kinase; Cdc7l1; CDC7-like 1; CDC7-related kinase; cell division cycle 7; cell division cycle 7 (S. cerevisiae); cell division cycle 7 homolog; cell division cycle 7-like 1; cell division cycle 7-like protein 1; cell division cycle 7-related protein kinase; HsCDC7; Hsk1; huCDC7; MGC117361; MGC126237; MGC126238; MGC91067; muCdc7
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国