产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
孕酮受体单克隆抗体(hPRa 6)
目录 :
MA5-12653
规格 :
500微升
价格 :
美国413.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
hPRa 6
反应物种 :
人类, 小鼠, 鸡, 牛, domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 15
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 鸡; 4 ug/ml; 图 2
González Morán M. Immunohistochemical localization of progesterone receptor isoforms and estrogen receptor alpha in the chicken oviduct magnum during development. Acta Histochem. 2015;117:681-7 pubmed 出版商
  • 免疫组化; 人类; 1:25
  • 免疫印迹; 人类
Kariagina A, Xie J, Leipprandt J, Haslam S. Amphiregulin mediates estrogen, progesterone, and EGFR signaling in the normal rat mammary gland and in hormone-dependent rat mammary cancers. Horm Cancer. 2010;1:229-44 pubmed 出版商
  • 免疫组化; 小鼠; 1:50
Zhang C, Mori M, Gao S, Li A, Hoshino I, Aupperlee M, et al. Tip30 deletion in MMTV-Neu mice leads to enhanced EGFR signaling and development of estrogen receptor-positive and progesterone receptor-negative mammary tumors. Cancer Res. 2010;70:10224-33 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
  • 免疫印迹; 小鼠; 2 ug/ml
Wargon V, Fernandez S, Goin M, Giulianelli S, Russo J, Lanari C. Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas. Breast Cancer Res Treat. 2011;126:319-32 pubmed 出版商
  • 免疫印迹; 小鼠; 2 ug/ml
Wargon V, Helguero L, Bolado J, Rojas P, Novaro V, Molinolo A, et al. Reversal of antiprogestin resistance and progesterone receptor isoform ratio in acquired resistant mammary carcinomas. Breast Cancer Res Treat. 2009;116:449-60 pubmed 出版商
  • 免疫组化; 人类; 1:200
Bukulmez O, Hardy D, Carr B, Word R, Mendelson C. Inflammatory status influences aromatase and steroid receptor expression in endometriosis. Endocrinology. 2008;149:1190-204 pubmed
  • 免疫组化; 人类; 1:40
Leslie K, Walter S, Torkko K, Stephens J, Thompson C, Singh M. Effect of tamoxifen on endometrial histology, hormone receptors, and cervical cytology: a prospective study with follow-up. Appl Immunohistochem Mol Morphol. 2007;15:284-93 pubmed
  • 免疫细胞化学; 人类; 1:500
Velarde M, Zeng Z, McQuown J, Simmen F, Simmen R. Kruppel-like factor 9 is a negative regulator of ligand-dependent estrogen receptor alpha signaling in Ishikawa endometrial adenocarcinoma cells. Mol Endocrinol. 2007;21:2988-3001 pubmed
  • 免疫组化; 人类
Singh M, Zaino R, Filiaci V, Leslie K. Relationship of estrogen and progesterone receptors to clinical outcome in metastatic endometrial carcinoma: a Gynecologic Oncology Group Study. Gynecol Oncol. 2007;106:325-33 pubmed
  • 免疫组化; 人类; 1:20
Oh S, Kim C, Park I, Romero R, Sohn Y, Moon K, et al. Progesterone receptor isoform (A/B) ratio of human fetal membranes increases during term parturition. Am J Obstet Gynecol. 2005;193:1156-60 pubmed
  • 免疫沉淀; 人类; 5 ug/time
  • 免疫组化; 人类; 1:25
  • 免疫印迹; 人类
Leslie K, Stein M, Kumar N, Dai D, Stephens J, Wandinger Ness A, et al. Progesterone receptor isoform identification and subcellular localization in endometrial cancer. Gynecol Oncol. 2005;96:32-41 pubmed
Nagy A, Sathe S, Atta A, Hammam A, Hsu W. Characterization of Nuclear Progesterone Receptor Isoforms in the Term Equine Placenta. Front Vet Sci. 2021;8:660177 pubmed 出版商
González Morán G, Camacho Arroyo I. Changes in the presence of progesterone receptor isoforms in the oviduct magnum of newly-hatched chicks after gonadotropins treatment. Life Sci. 2003;73:871-82 pubmed
González Morán G, García Izquierdo J, Camacho Arroyo I. Progesterone receptor isoforms in ovary of newly-hatched chick after gonadotropin treatment during embryonic development. Comp Biochem Physiol A Mol Integr Physiol. 2002;132:519-26 pubmed
González Agüero G, Ondarza R, Gamboa Dominguez A, Cerbon M, Camacho Arroyo I. Progesterone receptor isoforms expression pattern in human astrocytomas. Brain Res Bull. 2001;56:43-8 pubmed
图像
图像 1 :
赛默飞世尔 MA5-12653 图像 1
图像 2 :
赛默飞世尔 MA5-12653 图像 2
产品信息
产品类型 :
抗体
产品名称 :
孕酮受体单克隆抗体(hPRa 6)
目录# :
MA5-12653
规格 :
500微升
价格 :
美国413.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
牛, 鸡, 人类, 兔
应用 :
Immunocytochemistry: Assay-dependent, Immunoprecipitation: 2 µg/mL
物种 :
牛, 鸡, 人类, 兔
克隆 :
hPRa 6
抗体亚型 :
IgG2b
储存 :
4° C
描述 :
The progesterone receptor (PR) is a member of the steroid family of nuclear receptors. The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites. PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation. PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus. This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity. In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins. Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription. A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.
免疫原 :
Partially purified PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay-dependent, Immunoprecipitation: 2 µg/mL
别名 :
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国