产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
细胞角蛋白19单克隆抗体(A53-B/A2.26(Ks19.1))
目录 :
MA5-12663
规格 :
500微升
价格 :
美国315.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
A53-B/A2.26(Ks19.1)
反应物种 :
人类, 小鼠, 家羊, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, reverse phase protein lysate microarray
更多信息或购买 :
文章摘录数: 50
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 图 6c
Hendricks Wenger A, Aycock K, Nagai Singer M, Coutermarsh Ott S, Lorenzo M, Gannon J, et al. Establishing an immunocompromised porcine model of human cancer for novel therapy development with pancreatic adenocarcinoma and irreversible electroporation. Sci Rep. 2021;11:7584 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 7a
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1c
  • 免疫印迹; 人类; 1:1000; 图 2c
Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al. The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα. Nature. 2017;541:541-545 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1c
Erdogan Durmus S, Ozcan D, Yarikkaya E, Kurt A, Arslan A. CD56, HBME-1 and cytokeratin 19 expressions in papillary thyroid carcinoma and nodular thyroid lesions. J Res Med Sci. 2016;21:49 pubmed
  • 免疫组化; 人类; 1:100
Cetin S, Kir G, Yilmaz M. Thyroid Paraganglioma Diagnosed by Fine-Needle Aspiration Biopsy, Correlated With Histopathological Findings: Report of a Case. Diagn Cytopathol. 2016;44:643-7 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:2000; 图 4
  • 免疫印迹; 人类; 图 4
Fleury H, Communal L, Carmona E, Portelance L, Arcand S, Rahimi K, et al. Novel high-grade serous epithelial ovarian cancer cell lines that reflect the molecular diversity of both the sporadic and hereditary disease. Genes Cancer. 2015;6:378-398 pubmed
  • 免疫组化-石蜡切片; 人类; 图 s1
Labouba I, Le Page C, Communal L, Kristessen T, You X, Péant B, et al. Potential Cross-Talk between Alternative and Classical NF-κB Pathways in Prostate Cancer Tissues as Measured by a Multi-Staining Immunofluorescence Co-Localization Assay. PLoS ONE. 2015;10:e0131024 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1c
Trimboli P, Guidobaldi L, Amendola S, Nasrollah N, Romanelli F, Attanasio D, et al. Galectin-3 and HBME-1 improve the accuracy of core biopsy in indeterminate thyroid nodules. Endocrine. 2016;52:39-45 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 7
Huo C, Chew G, Hill P, Huang D, Ingman W, Hodson L, et al. High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium. Breast Cancer Res. 2015;17:79 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50
Fatourou E, Koskinas J, Karandrea D, Palaiologou M, Syminelaki T, Karanikolas M, et al. Keratin 19 protein expression is an independent predictor of survival in human hepatocellular carcinoma. Eur J Gastroenterol Hepatol. 2015;27:1094-102 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 1
Hines W, Yaswen P, Bissell M. Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias. Nat Commun. 2015;6:6927 pubmed 出版商
  • 免疫组化; 人类
Yassin F. Diagnostic criteria of well differentiated thyroid tumor of uncertain malignant potential; a histomorphological and immunohistochemical appraisal. J Egypt Natl Canc Inst. 2015;27:59-67 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Chen Q, Gu Y, Liu B. Clinicopathological characteristics of kidney mucinous tubular and spindle cell carcinoma. Int J Clin Exp Pathol. 2015;8:1007-12 pubmed
  • 免疫组化; 人类
Pınarlı F, Okten G, Beden U, Fisgin T, Kefeli M, Kara N, et al. Keratinocyte growth factor-2 and autologous serum potentiate the regenerative effect of mesenchymal stem cells in cornea damage in rats. Int J Ophthalmol. 2014;7:211-9 pubmed 出版商
  • 免疫组化; 人类; 1:100
Güney G, Tezel G, Kosemehmetoglu K, Yilmaz E, Balci S, Ersoy R, et al. Molecular features of follicular variant papillary carcinoma of thyroid: comparison of areas with or without classical nuclear features. Endocr Pathol. 2014;25:241-7 pubmed 出版商
  • 免疫组化; 人类; 1:100
Ozer S, Kayahan B, Cabbarzade C, Buğdayci M, Kosemehmetoglu K, Yücel O. Thyroid-like papillary adenocarcinoma of the nasopharynx with focal thyroglobulin expression. Pathology. 2013;45:622-4 pubmed 出版商
  • 免疫组化; 人类; 1:1500
Kim W, Ko Y, Hwang T, Han H, Lim S, Kim W, et al. A Case of Multifocal Papillary Thyroid Carcinoma Consisting of One Encapsulated Follicular Variant with BRAF K601E Mutation and Three Conventional Types with BRAF V600E Mutation. Korean J Pathol. 2013;47:293-8 pubmed 出版商
  • 免疫组化; 人类; 1:400
Zhang X, Claerhout S, Prat A, Dobrolecki L, Petrovic I, Lai Q, et al. A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res. 2013;73:4885-97 pubmed 出版商
  • 免疫细胞化学; 人类
Moffatt Jauregui C, Robinson B, de Moya A, Brockman R, Roman A, Cash M, et al. Establishment and characterization of a telomerase immortalized human gingival epithelial cell line. J Periodontal Res. 2013;48:713-21 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Takahashi Y, Kupferman M, Bell D, Jiffar T, Lee J, Xie T, et al. Establishment and characterization of novel cell lines from sinonasal undifferentiated carcinoma. Clin Cancer Res. 2012;18:6178-87 pubmed 出版商
  • 免疫组化; 人类
  • 免疫印迹; 人类
Létourneau I, Quinn M, Wang L, Portelance L, Caceres K, Cyr L, et al. Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer. BMC Cancer. 2012;12:379 pubmed 出版商
  • 免疫组化; 人类; 图 1
Guimei M, Baddour N, Elkaffash D, Abdou L, Taher Y. Gremlin in the pathogenesis of hepatocellular carcinoma complicating chronic hepatitis C: an immunohistochemical and PCR study of human liver biopsies. BMC Res Notes. 2012;5:390 pubmed 出版商
  • 免疫组化; 人类; 1:1500
Ko Y, Hwang T, Han H, Lim S, Kim W, Oh S. Primary pure squamous cell carcinoma of the thyroid: report and histogenic consideration of a case involving a BRAF mutation. Pathol Int. 2012;62:43-8 pubmed 出版商
  • 免疫组化; 人类; 1:150
Sarsik B, Simsir A, Karaarslan S, Sen S. Mucinous tubular and spindle cell carcinoma of kidney and problems in diagnosis. Turk Patoloji Derg. 2011;27:116-26 pubmed 出版商
  • 免疫组化; 人类
Eloy C, Vinagre J, Cameselle Teijeiro J, Paiva M, Soares P, Sobrinho Simoes M. Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?. Int J Surg Pathol. 2011;19:276-80 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500
Sartoneva R, Haimi S, Miettinen S, Mannerström B, Haaparanta A, Sándor G, et al. Comparison of a poly-L-lactide-co-?-caprolactone and human amniotic membrane for urothelium tissue engineering applications. J R Soc Interface. 2011;8:671-7 pubmed 出版商
  • 免疫组化; 人类; 1:1000
Moreira J, Cabezon T, Gromova I, Gromov P, Timmermans Wielenga V, Machado I, et al. Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy. Mol Oncol. 2010;4:539-61 pubmed 出版商
  • 免疫组化; 人类; 1:100
Huang S, Xu Y, Wu C, Sha D, Fu X. In vitro constitution and in vivo implantation of engineered skin constructs with sweat glands. Biomaterials. 2010;31:5520-5 pubmed 出版商
  • 免疫组化; 人类; 1:50
Nasr M, Mukhopadhyay S, Zhang S, Katzenstein A. Absence of the BRAF mutation in HBME1+ and CK19+ atypical cell clusters in Hashimoto thyroiditis: supportive evidence against preneoplastic change. Am J Clin Pathol. 2009;132:906-12 pubmed 出版商
  • 免疫印迹; 人类; 1:200
Chang C, Chiou P, Chen W, Li Y, Yiu J, Cheng Y, et al. Assessment of the tumorigenesis and drug susceptibility of three new canine mammary tumor cell lines. Res Vet Sci. 2010;88:285-93 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50
Behbod F, Kittrell F, LaMarca H, Edwards D, Kerbawy S, Heestand J, et al. An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res. 2009;11:R66 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫组化; 人类
Metallo C, Azarin S, Moses L, Ji L, de Pablo J, Palecek S. Human embryonic stem cell-derived keratinocytes exhibit an epidermal transcription program and undergo epithelial morphogenesis in engineered tissue constructs. Tissue Eng Part A. 2010;16:213-23 pubmed 出版商
  • 免疫细胞化学; 小鼠
Kawashima M, Kawakita T, Yoshida S, Shimmura S, Tsubota K. Nucleostemin as a possible progenitor marker of corneal epithelial cells. Mol Vis. 2009;15:1162-8 pubmed
  • 免疫细胞化学; 人类
  • 免疫组化; 人类
  • 免疫印迹; 人类
Celis J, Gromova I, Cabezon T, Gromov P, Shen T, Timmermans Wielenga V, et al. Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease. Mol Oncol. 2007;1:321-49 pubmed 出版商
  • 免疫组化; 人类
  • 免疫印迹; 人类
Celis J, Moreira J, Gromova I, Cabezon T, Gromov P, Shen T, et al. Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia. Mol Oncol. 2007;1:97-119 pubmed 出版商
  • 免疫组化; 人类; 1:100
Li H, Zhou G, Fu X, Zhang L. Antigen expression of human eccrine sweat glands. J Cutan Pathol. 2009;36:318-24 pubmed 出版商
  • 免疫组化; 人类
Celis J, Gromov P, Cabezon T, Moreira J, Friis E, Jirstrom K, et al. 15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma. Mol Cell Proteomics. 2008;7:1795-809 pubmed 出版商
  • 免疫细胞化学; 家羊; 1:100
Liu Y, Zhou H, Gao F. Isolation and identification of stem cells from adult cashmere goat skin. Int J Dermatol. 2008;47:551-6 pubmed 出版商
  • 免疫组化; 人类
Svoboda M, Sellner F, Ekmekcioglu C, Klimpfinger M, Jaeger W, Thalhammer T. Expression of estrogen-metabolizing enzymes and estrogen receptors in cholelithiasis gallbladder. Biomed Pharmacother. 2008;62:690-6 pubmed 出版商
  • 免疫组化; 猕猴; 1:100
Wood C, Hester J, Cline J. Mammary gland development in early pubertal female macaques. Toxicol Pathol. 2007;35:795-805 pubmed
  • 免疫细胞化学; 家羊
Islam M, Zhou H. Isolation and characterization of putative epidermal stem cells derived from Cashmere goat fetus. Eur J Dermatol. 2007;17:302-8 pubmed
  • 免疫组化; 人类
Gurbuz Y, Kose N, Aydin O, Ozturk M. An immunohistochemical profile of giant cell carcinoma of the larynx. Auris Nasus Larynx. 2007;34:413-6 pubmed
  • 免疫组化; 人类; 1:50
Nasr M, Mukhopadhyay S, Zhang S, Katzenstein A. Immunohistochemical markers in diagnosis of papillary thyroid carcinoma: Utility of HBME1 combined with CK19 immunostaining. Mod Pathol. 2006;19:1631-7 pubmed
  • 免疫组化; 人类
Yesim G, Gupse T, Zafer U, Ahmet A. Mesenchymal hamartoma of the liver in adulthood: immunohistochemical profiles, clinical and histopathological features in two patients. J Hepatobiliary Pancreat Surg. 2005;12:502-7 pubmed
  • 免疫印迹; 人类
Moreira J, Ohlsson G, Rank F, Celis J. Down-regulation of the tumor suppressor protein 14-3-3sigma is a sporadic event in cancer of the breast. Mol Cell Proteomics. 2005;4:555-69 pubmed
Schreurs O, Karatsaidis A, Balta M, Grung B, Hals E, Schenck K. Expression of keratins 8, 18, and 19 in epithelia of atrophic oral lichen planus. Eur J Oral Sci. 2020;128:7-17 pubmed 出版商
Shik Mun K, Arora K, Huang Y, Yang F, Yarlagadda S, Ramananda Y, et al. Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders. Nat Commun. 2019;10:3124 pubmed 出版商
Aust S, Obrist P, Jaeger W, Klimpfinger M, Tucek G, Wrba F, et al. Subcellular localization of the ABCG2 transporter in normal and malignant human gallbladder epithelium. Lab Invest. 2004;84:1024-36 pubmed
Apaydin R, Gurbuz Y, Bayramgurler D, Muezzinoglu B, Bilen N. Cytokeratin expression in lichen amyloidosus and macular amyloidosis. J Eur Acad Dermatol Venereol. 2004;18:305-9 pubmed
Gudjonsson T, Villadsen R, Nielsen H, Rønnov Jessen L, Bissell M, Petersen O. Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties. Genes Dev. 2002;16:693-706 pubmed
图像
图像 1 :
赛默飞世尔 MA5-12663 图像 1
图像 2 :
赛默飞世尔 MA5-12663 图像 2
Formalin-fixed, paraffin-embedded human skin stained with Keratin 19 antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of epithelial cells in the sweat glands.
产品信息
产品类型 :
抗体
产品名称 :
细胞角蛋白19单克隆抗体(A53-B/A2.26(Ks19.1))
目录# :
MA5-12663
规格 :
500微升
价格 :
美国315.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 2 µg/mL
物种 :
人类
克隆 :
A53-B/A2.26(Ks19.1)
抗体亚型 :
IgG2a, lambda
储存 :
4° C
描述 :
Cytokeratin 19 is part of a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40-68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. For example, cytokeratin 19 is not expressed in hepatocytes, therefore, it is useful in the identification of liver metastasis.
免疫原 :
Human breast cancer MCF-7 cells
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 2 µg/mL
别名 :
40-kDa keratin intermediate filament; AI663979; C K1CS; CK 19; CK19; CK-19; cytokeratin 19; cytokeratin-19; EndoC; K19; K1CS; Ka19; keratin 19; keratin 19, type I; keratin complex 1, acidic, gene 19; keratin, type I cytoskeletal 19; keratin, type I, 40-kd; keratin-19; Krt-1.19; Krt1-19; Krt19; LOC100344434; MGC15366; Type I keratin Ka19
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国