产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
细胞周期蛋白D3单克隆抗体(DCS-22)
目录 :
MA5-12717
规格 :
500微升
价格 :
美国447.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DCS-22
反应物种 :
人类, 小鼠, 大鼠, 犬
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 33
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| Filipits M, Pirker R, Dunant A, Lantuejoul S, Schmid K, Huynh A, et al. Cell cycle regulators and outcome of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer: the International Adjuvant Lung Cancer Trial Biologic Program. J Clin Oncol. 2007;25:2735-40 pubmed
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| Haraguchi T, Koujin T, Osakada H, Kojidani T, Mori C, Masuda H, et al. Nuclear localization of barrier-to-autointegration factor is correlated with progression of S phase in human cells. J Cell Sci. 2007;120:1967-77 pubmed
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| Paternot S, Dumont J, Roger P. Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations by growth factors and TSH of human thyrocytes in primary culture. Mol Endocrinol. 2006;20:3279-92 pubmed
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| Leslie K, Lang C, Devgan G, Azare J, Berishaj M, Gerald W, et al. Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer Res. 2006;66:2544-52 pubmed
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| Piva R, Chiarle R, Manazza A, Taulli R, Simmons W, Ambrogio C, et al. Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas. Blood. 2006;107:689-97 pubmed
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| Fu K, Weisenburger D, Greiner T, Dave S, Wright G, Rosenwald A, et al. Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling. Blood. 2005;106:4315-21 pubmed
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| Fortemaison N, Blancquaert S, Dumont J, Maenhaut C, Aktories K, Roger P, et al. Differential involvement of the actin cytoskeleton in differentiation and mitogenesis of thyroid cells: inactivation of Rho proteins contributes to cyclic adenosine monophosphate-dependent gene expression but prevents mitogenesis. Endocrinology. 2005;146:5485-95 pubmed
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| Wong S, Chan A, Lo E, Lo Y. Nuclear beta-catenin expression is rare and its potential association with short survival in colorectal signet-ring cell carcinoma. Appl Immunohistochem Mol Morphol. 2005;13:248-51 pubmed
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| Mermelshtein A, Gerson A, Walfisch S, Delgado B, Shechter Maor G, Delgado J, et al. Expression of D-type cyclins in colon cancer and in cell lines from colon carcinomas. Br J Cancer. 2005;93:338-45 pubmed
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| Siitonen T, Koistinen P, Savolainen E. Increase in Ara-C cytotoxicity in the presence of valproate, a histone deacetylase inhibitor, is associated with the concurrent expression of cyclin D1 and p27(Kip 1) in acute myeloblastic leukemia cells. Leuk Res. 2005;29:1335-42 pubmed
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| Gloghini A, Gaidano G, Larocca L, Pierconti F, Cingolani A, Dal Maso L, et al. Expression of cyclin-dependent kinase inhibitor p27(Kip1) in AIDS-related diffuse large-cell lymphomas is associated with Epstein-Barr virus-encoded latent membrane protein 1. Am J Pathol. 2002;161:163-71 pubmed
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Bockstaele L, Kooken H, Libert F, Paternot S, Dumont J, De Launoit Y, et al. Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". Mol Cell Biol. 2006;26:5070-85 pubmed
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Jirawatnotai S, Aziyu A, Osmundson E, Moons D, Zou X, Kineman R, et al. Cdk4 is indispensable for postnatal proliferation of the anterior pituitary. J Biol Chem. 2004;279:51100-6 pubmed
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Petermann A, Hiromura K, Pippin J, Blonski M, Couser W, Kopp J, et al. Differential expression of d-type cyclins in podocytes in vitro and in vivo. Am J Pathol. 2004;164:1417-24 pubmed
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Faast R, White J, Cartwright P, Crocker L, Sarcevic B, Dalton S. Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a). Oncogene. 2004;23:491-502 pubmed
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Piva R, Liu J, Chiarle R, Podda A, Pagano M, Inghirami G. In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation. Mol Cell Biol. 2002;22:8375-87 pubmed
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Filipits M, Jaeger U, Pohl G, Stranzl T, Simonitsch I, Kaider A, et al. Cyclin D3 is a predictive and prognostic factor in diffuse large B-cell lymphoma. Clin Cancer Res. 2002;8:729-33 pubmed
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Tong W, Pollard J. Genetic evidence for the interactions of cyclin D1 and p27(Kip1) in mice. Mol Cell Biol. 2001;21:1319-28 pubmed
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Servant M, Coulombe P, Turgeon B, Meloche S. Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms. J Cell Biol. 2000;148:543-56 pubmed
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Ladha M, Lee K, Upton T, Reed M, Ewen M. Regulation of exit from quiescence by p27 and cyclin D1-CDK4. Mol Cell Biol. 1998;18:6605-15 pubmed
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Dei Tos A, Piccinin S, Doglioni C, Vukosavljevic T, Mentzel T, Boiocchi M, et al. Molecular aberrations of the G1-S checkpoint in myxoid and round cell liposarcoma. Am J Pathol. 1997;151:1531-9 pubmed
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图像
图像 1 :
图像 2 :
图像 3 :
Formalin-fixed, paraffin-embedded human tonsil stained with Cyclin D3 antibody using peroxidase-conjugate and AEC chromogen. Note nuclear staining of cells.
产品信息
产品类型 :
抗体
产品名称 :
细胞周期蛋白D3单克隆抗体(DCS-22)
目录# :
MA5-12717
规格 :
500微升
价格 :
美国447.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
Human, Mouse, Non-human primate, Rat
应用 :
Immunohistochemistry (Paraffin): 1:25, Immunoprecipitation: 2 µg/mL, Western Blot: 1 µg/mL
物种 :
Human, Mouse, Non-human primate, Rat
克隆 :
DCS-22
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
The immunogen for the anti-h-Cyclin D3 was a recombinant full length Cyclin D3 protein recognizing a 34 kD protein. Cyclin D3 is a G1 cyclin closely related to Cyclins D1 and D2 phase progression. Like Cyclin D1 and Cyclin D2, it is activated by the same mechanisms and can phosphorylate pRB when associated with cdk4 and cdk6.
免疫原 :
纯化人类重组全长细胞周期蛋白D3蛋白
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:25, Immunoprecipitation: 2 µg/mL, Western Blot: 1 µg/mL
别名 :
9230106B05Rik; AA682053; AL024085; AW146355; C78795; CCND 3; Ccnd3; CGD3; cyclin D3; CyclinD3; Cyl-3; D3 type cyclin; D3-type cyclin; G1/S-specific cyclin-D3; OTTHUMP00000223415; RP5-973N23.3
更多信息或购买 :
公司信息
赛默飞世尔