产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
胶原II单克隆抗体(2B1.5)
目录 :
MA5-12789
规格 :
500微升
价格 :
美国406.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2B1.5
反应物种 :
豚鼠, domestic goat, , 人类, 小鼠, 大鼠, , , pigs , 家羊, domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 66
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 图 1c
Varela Eirin M, Carpintero Fernández P, Sánchez Temprano A, Varela Vazquez A, Paíno C, Casado Diaz A, et al. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging (Albany NY). 2020;12:15882-15905 pubmed 出版商
  • 免疫组化; 马; 1:400; 表 1
Kremer A, Ribitsch I, Reboredo J, Dürr J, Egerbacher M, Jenner F, et al. Three-Dimensional Coculture of Meniscal Cells and Mesenchymal Stem Cells in Collagen Type I Hydrogel on a Small Intestinal Matrix-A Pilot Study Toward Equine Meniscus Tissue Engineering. Tissue Eng Part A. 2017;23:390-402 pubmed 出版商
  • 免疫组化; 大鼠; 表 1
Cakici C, Buyrukcu B, Duruksu G, Haliloglu A, Aksoy A, Isik A, et al. Recovery of fertility in azoospermia rats after injection of adipose-tissue-derived mesenchymal stem cells: the sperm generation. Biomed Res Int. 2013;2013:529589 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
Belluoccio D, Rowley L, Little C, Bateman J. Maintaining mRNA integrity during decalcification of mineralized tissues. PLoS ONE. 2013;8:e58154 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
Kalwani N, Ong C, Lysaght A, Haward S, McKinley G, Stankovic K. Quantitative polarized light microscopy of unstained mammalian cochlear sections. J Biomed Opt. 2013;18:26021 pubmed 出版商
  • 免疫组化; 小鼠
Kawai M, Kinoshita S, Kimoto A, Hasegawa Y, Miyagawa K, Yamazaki M, et al. FGF23 suppresses chondrocyte proliferation in the presence of soluble ?-Klotho both in vitro and in vivo. J Biol Chem. 2013;288:2414-27 pubmed 出版商
  • 免疫组化; 大鼠; 1:50
Rui Y, Lui P, Wong Y, Tan Q, Chan K. Altered fate of tendon-derived stem cells isolated from a failed tendon-healing animal model of tendinopathy. Stem Cells Dev. 2013;22:1076-85 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100
Katebi N, Kolpakova Hart E, Lin C, Olsen B. The mouse palate and its cellular responses to midpalatal suture expansion forces. Orthod Craniofac Res. 2012;15:148-58 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100
Kang E, Ha K, Kim Y. Fate of transplanted bone marrow derived mesenchymal stem cells following spinal cord injury in rats by transplantation routes. J Korean Med Sci. 2012;27:586-93 pubmed 出版商
  • 免疫组化; domestic rabbit; 1:100
Suwannaloet W, Laupattarakasem W, Sukon P, Ong Chai S, Laupattarakasem P. Combined effect of subchondral drilling and hyaluronic acid with/without diacerein in full-thickness articular cartilage lesion in rabbits. ScientificWorldJournal. 2012;2012:310745 pubmed 出版商
  • 免疫组化; domestic rabbit; 1:500
Zhang L, Yuan T, Guo L, Zhang X. An in vitro study of collagen hydrogel to induce the chondrogenic differentiation of mesenchymal stem cells. J Biomed Mater Res A. 2012;100:2717-25 pubmed 出版商
  • 免疫组化; 小鼠; 1:400
Masago Y, Hosoya A, Kawasaki K, Kawano S, Nasu A, Toguchida J, et al. The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation. J Cell Sci. 2012;125:1118-28 pubmed 出版商
  • 免疫组化; 小鼠
Koshimizu T, Kawai M, Kondou H, Tachikawa K, Sakai N, Ozono K, et al. Vinculin functions as regulator of chondrogenesis. J Biol Chem. 2012;287:15760-75 pubmed 出版商
  • 免疫组化; 牛
Kuo Y, Wang C. Cartilage regeneration by culturing chondrocytes in scaffolds grafted with TATVHL peptide. Colloids Surf B Biointerfaces. 2012;93:235-40 pubmed 出版商
  • 免疫组化; 牛
Kuo Y, Chung C. Chondrogenesis in scaffolds with surface modification of elastin and poly-L-lysine. Colloids Surf B Biointerfaces. 2012;93:85-91 pubmed 出版商
  • 免疫组化; pigs ; 1:200
Lyu S, Kuo Y, Lin M, Hsieh W, Chuang C. Application of albumin-grafted scaffolds to promote neocartilage formation. Colloids Surf B Biointerfaces. 2012;91:296-301 pubmed 出版商
  • 免疫组化; 牛
Kuo Y, Wang C. Surface modification with peptide for enhancing chondrocyte adhesion and cartilage regeneration in porous scaffolds. Colloids Surf B Biointerfaces. 2011;84:63-70 pubmed 出版商
  • 免疫组化; 大鼠
Karaoz E, Okcu A, Saglam O, Genc Z, Ayhan S, Kasap M. Pancreatic islet derived stem cells can express co-stimulatory molecules of antigen-presenting cells. Transplant Proc. 2010;42:3663-70 pubmed 出版商
  • 免疫组化; 牛; 1:100
Kuo Y, Tsai Y. Heparin-conjugated scaffolds with pore structure of inverted colloidal crystals for cartilage regeneration. Colloids Surf B Biointerfaces. 2011;82:616-23 pubmed 出版商
  • 免疫组化; 大鼠
Adas G, Arikan S, Karatepe O, Kemik O, Ayhan S, Karaoz E, et al. Mesenchymal stem cells improve the healing of ischemic colonic anastomoses (experimental study). Langenbecks Arch Surg. 2011;396:115-26 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1
Karaoz E, Okçu A, Gacar G, Sağlam O, Yuruker S, Kenar H. A comprehensive characterization study of human bone marrow mscs with an emphasis on molecular and ultrastructural properties. J Cell Physiol. 2011;226:1367-82 pubmed 出版商
  • 免疫组化; 人类
Hildner F, Peterbauer A, Wolbank S, Nürnberger S, Marlovits S, Redl H, et al. FGF-2 abolishes the chondrogenic effect of combined BMP-6 and TGF-beta in human adipose derived stem cells. J Biomed Mater Res A. 2010;94:978-87 pubmed 出版商
  • 免疫组化; 牛; 1:100
Kuo Y, Tsai Y. Inverted colloidal crystal scaffolds for uniform cartilage regeneration. Biomacromolecules. 2010;11:731-9 pubmed 出版商
  • 免疫组化; 家羊
Saw K, Hussin P, Loke S, Azam M, Chen H, Tay Y, et al. Articular cartilage regeneration with autologous marrow aspirate and hyaluronic Acid: an experimental study in a goat model. Arthroscopy. 2009;25:1391-400 pubmed 出版商
  • 免疫细胞化学; 人类
Karaoz E, Doğan B, Aksoy A, Gacar G, Akyuz S, Ayhan S, et al. Isolation and in vitro characterisation of dental pulp stem cells from natal teeth. Histochem Cell Biol. 2010;133:95-112 pubmed 出版商
  • 免疫组化; 人类
Knutsson J, Bagger Sjoback D, von Unge M. Collagen type distribution in the healthy human tympanic membrane. Otol Neurotol. 2009;30:1225-9 pubmed 出版商
  • 免疫细胞化学; 大鼠
Karaoz E, Aksoy A, Ayhan S, Sariboyaci A, Kaymaz F, Kasap M. Characterization of mesenchymal stem cells from rat bone marrow: ultrastructural properties, differentiation potential and immunophenotypic markers. Histochem Cell Biol. 2009;132:533-46 pubmed 出版商
  • 免疫组化; 豚鼠
Bernstein P, Dong M, Graupner S, Graupher S, Corbeil D, Gelinsky M, et al. Sox9 expression of alginate-encapsulated chondrocytes is stimulated by low cell density. J Biomed Mater Res A. 2009;91:910-8 pubmed 出版商
  • 免疫组化; domestic rabbit
Pfeffer B, Bernstein S, Bartels S. Preservation of structure and immunoreactivity at the vitreoretinal interface of the rabbit eye. Graefes Arch Clin Exp Ophthalmol. 2009;247:193-205 pubmed 出版商
  • 免疫组化; domestic goat; 1:200
Wong M, Qin L, Lee K, Leung K. Articular cartilage increases transition zone regeneration in bone-tendon junction healing. Clin Orthop Relat Res. 2009;467:1092-100 pubmed 出版商
  • 免疫组化; 牛
Kuo Y, Hsu Y. Tissue-engineered polyethylene oxide/chitosan scaffolds as potential substitutes for articular cartilage. J Biomed Mater Res A. 2009;91:277-87 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
Kretlow J, Jin Y, Liu W, Zhang W, Hong T, Zhou G, et al. Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells. BMC Cell Biol. 2008;9:60 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Lui P, Fu S, Chan L, Hung L, Chan K. Chondrocyte phenotype and ectopic ossification in collagenase-induced tendon degeneration. J Histochem Cytochem. 2009;57:91-100 pubmed 出版商
  • 免疫组化; 大鼠; 1:200
Wang Z, Yang Z, He X, Wang L, Li L, Tu J. Effects of RNAi-mediated inhibition of aggrecanase-1 and aggrecanase-2 on rat costochondral chondrocytes in vitro. Acta Pharmacol Sin. 2008;29:1215-26 pubmed 出版商
  • 免疫细胞化学; 大鼠
Yingst S, Bloxham K, Warner L, Brown R, Cole J, Kenoyer L, et al. Characterization of collagenous matrix assembly in a chondrocyte model system. J Biomed Mater Res A. 2009;90:247-55 pubmed 出版商
  • 免疫组化; 人类
Hui T, Cheung K, Cheung W, Chan D, Chan B. In vitro chondrogenic differentiation of human mesenchymal stem cells in collagen microspheres: influence of cell seeding density and collagen concentration. Biomaterials. 2008;29:3201-12 pubmed 出版商
  • 免疫组化; pigs ; 1:100
Bilgen B, Orsini E, Aaron R, Ciombor D. FBS suppresses TGF-beta1-induced chondrogenesis in synoviocyte pellet cultures while dexamethasone and dynamic stimuli are beneficial. J Tissue Eng Regen Med. 2007;1:436-42 pubmed 出版商
  • 免疫组化; 小鼠
Hou B, Fukai N, Olsen B. Mechanical force-induced midpalatal suture remodeling in mice. Bone. 2007;40:1483-93 pubmed
  • 免疫印迹; 大鼠; 2 ug/ml
Schreiweis M, Butler J, Kulkarni N, Knierman M, Higgs R, Halladay D, et al. A proteomic analysis of adult rat bone reveals the presence of cartilage/chondrocyte markers. J Cell Biochem. 2007;101:466-76 pubmed
  • 免疫组化; 人类; 1:10
Romito L, Ameer G. Mechanical interlocking of engineered cartilage to an underlying polymeric substrate: towards a biohybrid tissue equivalent. Ann Biomed Eng. 2006;34:737-47 pubmed
  • 免疫印迹; 人类
Lin Y, Luo E, Chen X, Liu L, Qiao J, Yan Z, et al. Molecular and cellular characterization during chondrogenic differentiation of adipose tissue-derived stromal cells in vitro and cartilage formation in vivo. J Cell Mol Med. 2005;9:929-39 pubmed
  • 免疫组化; 人类; 1:500
Hecht J, Hayes E, Haynes R, Cole W, Long R, Farach Carson M, et al. Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes. Differentiation. 2005;73:212-21 pubmed
  • 免疫组化; 小鼠
Wang Y, Xiao R, Yang F, Karim B, Iacovelli A, Cai J, et al. Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development. 2005;132:3537-48 pubmed
  • 免疫组化; 人类
Peker S, Kurtkaya Yapicier O, Kilic T, Pamir M. Microsurgical anatomy of the lateral walls of the pituitary fossa. Acta Neurochir (Wien). 2005;147:641-8; discussion 649 pubmed
  • 免疫印迹; 小鼠
Ortega N, Behonick D, Colnot C, Cooper D, Werb Z. Galectin-3 is a downstream regulator of matrix metalloproteinase-9 function during endochondral bone formation. Mol Biol Cell. 2005;16:3028-39 pubmed
  • 免疫印迹; domestic rabbit
Kose G, Korkusuz F, Ozkul A, Soysal Y, Ozdemir T, Yildiz C, et al. Tissue engineered cartilage on collagen and PHBV matrices. Biomaterials. 2005;26:5187-97 pubmed
  • 免疫组化; 人类; 1:100
Bobryshev Y. Transdifferentiation of smooth muscle cells into chondrocytes in atherosclerotic arteries in situ: implications for diffuse intimal calcification. J Pathol. 2005;205:641-50 pubmed
Yabe R, Chung S, Murayama M, Kubo S, Shimizu K, Akahori Y, et al. TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens. Nat Commun. 2021;12:94 pubmed 出版商
Fernández Iglesias Á, Fuente R, Gil Peña H, Alonso Durán L, García Bengoa M, Santos F, et al. Innovative Three-Dimensional Microscopic Analysis of Uremic Growth Plate Discloses Alterations in the Process of Chondrocyte Hypertrophy: Effects of Growth Hormone Treatment. Int J Mol Sci. 2020;21: pubmed 出版商
Shpargel K, Mangini C, Xie G, Ge K, Magnuson T. The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology. Development. 2020;147: pubmed 出版商
Zhang Y, Annusver K, Sunadome K, Kameneva P, Edwards S, Lei G, et al. Epiphyseal Cartilage Formation Involves Differential Dynamics of Various Cellular Populations During Embryogenesis. Front Cell Dev Biol. 2020;8:122 pubmed 出版商
Rubí Sans G, Recha Sancho L, Perez Amodio S, Mateos Timoneda M, Semino C, Engel E. Development of a Three-Dimensional Bioengineered Platform for Articular Cartilage Regeneration. Biomolecules. 2019;10: pubmed 出版商
Varela Eirin M, Varela Vazquez A, Guitián Caamaño A, Paíno C, Mato V, Largo R, et al. Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis. Cell Death Dis. 2018;9:1166 pubmed 出版商
Zhang L, Chen Q, Wang H, Yang J, Sheng S. Andrographolide mitigates IL‑1β‑induced human nucleus pulposus cells degeneration through the TLR4/MyD88/NF‑κB signaling pathway. Mol Med Rep. 2018;18:5427-5436 pubmed 出版商
Bahmanpour S, Ghasemi M, Sadeghi Naini M, Kashani I. Effects of Platelet-Rich Plasma & Platelet-Rich Fibrin with and without Stromal Cell-Derived Factor-1 on Repairing Full-Thickness Cartilage Defects in Knees of Rabbits. Iran J Med Sci. 2016;41:507-517 pubmed
Huang H, Wang S, Gui J, Shen H. A study to identify and characterize the stem/progenitor cell in rabbit meniscus. Cytotechnology. 2016;68:2083-103 pubmed 出版商
Zhang Y, Sheu T, Hoak D, Shen J, Hilton M, Zuscik M, et al. CCN1 Regulates Chondrocyte Maturation and Cartilage Development. J Bone Miner Res. 2016;31:549-59 pubmed 出版商
Mirando A, Liu Z, Moore T, Lang A, Kohn A, Osinski A, et al. RBP-J?-dependent Notch signaling is required for murine articular cartilage and joint maintenance. Arthritis Rheum. 2013;65:2623-33 pubmed 出版商
Perrier Groult E, Pasdeloup M, Malbouyres M, Galera P, Mallein Gerin F. Control of collagen production in mouse chondrocytes by using a combination of bone morphogenetic protein-2 and small interfering RNA targeting Col1a1 for hydrogel-based tissue-engineered cartilage. Tissue Eng Part C Methods. 2013;19:652-64 pubmed 出版商
Chang C, Ramaswamy G, Serra R. Depletion of primary cilia in articular chondrocytes results in reduced Gli3 repressor to activator ratio, increased Hedgehog signaling, and symptoms of early osteoarthritis. Osteoarthritis Cartilage. 2012;20:152-61 pubmed 出版商
Locker M, Kellermann O, Boucquey M, Khun H, Huerre M, Poliard A. Paracrine and autocrine signals promoting full chondrogenic differentiation of a mesoblastic cell line. J Bone Miner Res. 2004;19:100-10 pubmed
Nakayama N, Duryea D, Manoukian R, Chow G, Han C. Macroscopic cartilage formation with embryonic stem-cell-derived mesodermal progenitor cells. J Cell Sci. 2003;116:2015-28 pubmed
Dabovic B, Chen Y, Colarossi C, Zambuto L, Obata H, Rifkin D. Bone defects in latent TGF-beta binding protein (Ltbp)-3 null mice; a role for Ltbp in TGF-beta presentation. J Endocrinol. 2002;175:129-41 pubmed
Wang W, Wang Y, Reginato A, Plotkina S, Gridley T, Olsen B. Growth defect in Grg5 null mice is associated with reduced Ihh signaling in growth plates. Dev Dyn. 2002;224:79-89 pubmed
Dabovic B, Chen Y, Colarossi C, Obata H, Zambuto L, Perle M, et al. Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability. J Cell Biol. 2002;156:227-32 pubmed
Odelberg S, Kollhoff A, Keating M. Dedifferentiation of mammalian myotubes induced by msx1. Cell. 2000;103:1099-109 pubmed
图像
图像 1 :
赛默飞世尔 MA5-12789 图像 1
产品信息
产品类型 :
抗体
产品名称 :
胶原II单克隆抗体(2B1.5)
目录# :
MA5-12789
规格 :
500微升
价格 :
美国406.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
牛, 鸡, 人类, 小鼠, 大鼠
应用 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1-2 µg/mL
物种 :
牛, 鸡, 人类, 小鼠, 大鼠
克隆 :
2B1.5
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
免疫原 :
A purified preparation of lathyritic type II collagen from embryonic chicken sternum
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1-2 µg/mL
别名 :
alpha 1 type II procollagen; alpha 1 type IIA collagen; alpha 1 type IIA collagen precursor; alpha collagen type II; alpha-1 type II collagen; ANFH; AOM; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; CB11; CG2A1A; CGA; Chondrocalcin; COL11A3; Col2; Col2a; col2a1; Col2a-1; col2a1.L; col2a1a; col2a1-a; col2a1-b; Collagen 2; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen type II (Col2A1) gene, enhancer region; collagen type II alpha 1 chain; collagen type IIA; collagen, type II, alpha 1; collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital); collagen, type II, alpha 1 L homeolog; COLLII; cyanogen bromide; Del1; disproportionate micromelia; Dmm; Lpk; M100856; MGC131516; pro alpha1 type II collagen; pro-alpha 1(II); pro-alpha-1 type II collagen; procollagen alpha 1(II); Procollagen II alpha 1; procollagen, type II, alpha 1; Rgsc856; SEDC; STL1; type II collagen; type II collagen cyanogen bromide fragment CB10; type II collogen cyanogen bromide fragment CB8; unnamed protein product; X-col II; xcol2a1; XELAEV_18013523mg
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国