产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
微管相关蛋白2单克隆抗体(AP20)
目录 :
MA5-12823
规格 :
500微升
价格 :
美国446.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AP20
反应物种 :
Epinephelus, African green monkey, 人类, 小鼠, 大鼠, 牛
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 29
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 s7a
Tamaki Y, Shodai A, Morimura T, Hikiami R, Minamiyama S, Ayaki T, et al. Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specific intrabody with dual proteolytic signals. Sci Rep. 2018;8:6030 pubmed 出版商
  • 免疫细胞化学; Epinephelus; 图 1a
Chiang Y, Wu Y, Chi S. Interleukin-1β secreted from betanodavirus-infected microglia caused the death of neurons in giant grouper brains. Dev Comp Immunol. 2017;70:19-26 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 表 1
Buren C, Tu G, Parsons M, Sepers M, Raymond L. Influence of cortical synaptic input on striatal neuronal dendritic arborization and sensitivity to excitotoxicity in corticostriatal coculture. J Neurophysiol. 2016;116:380-90 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400
Yarchoan M, Toledo J, Lee E, Arvanitakis Z, Kazi H, Han L, et al. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathol. 2014;128:679-89 pubmed 出版商
  • 免疫组化; 大鼠; 表 1
Cakici C, Buyrukcu B, Duruksu G, Haliloglu A, Aksoy A, Isik A, et al. Recovery of fertility in azoospermia rats after injection of adipose-tissue-derived mesenchymal stem cells: the sperm generation. Biomed Res Int. 2013;2013:529589 pubmed 出版商
  • 免疫组化; 人类
Sarnat H, Flores Sarnat L. Precocious and delayed neocortical synaptogenesis in fetal holoprosencephaly. Clin Neuropathol. 2013;32:255-68 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:6000; 图 7
Karasinska J, de Haan W, Franciosi S, Ruddle P, Fan J, Kruit J, et al. ABCA1 influences neuroinflammation and neuronal death. Neurobiol Dis. 2013;54:445-55 pubmed 出版商
  • 免疫组化; 人类
Sarnat H, Flores Sarnat L, Crino P, Hader W, Bello Espinosa L. Hemimegalencephaly: foetal tauopathy with mTOR hyperactivation and neuronal lipidosis. Folia Neuropathol. 2012;50:330-45 pubmed
  • 免疫细胞化学; 人类
Raso A, Vecchio D, Cappelli E, Ropolo M, Poggi A, Nozza P, et al. Characterization of glioma stem cells through multiple stem cell markers and their specific sensitization to double-strand break-inducing agents by pharmacological inhibition of ataxia telangiectasia mutated protein. Brain Pathol. 2012;22:677-88 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:500
Sheng H, Xu Y, Chen Y, Zhang Y, Xu X, He C, et al. CRH-R1 and CRH-R2 differentially modulate dendritic outgrowth of hippocampal neurons. Endocrine. 2012;41:458-64 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200
Zhou Z, Xu Y, Zhong Q, Zheng J. Phenotypic characteristics of hybrid cells generated by transferring neuronal nuclei into bone marrow stromal cell cytoplasts. Brain Res Bull. 2012;87:303-11 pubmed 出版商
  • 免疫组化; 大鼠
Adas G, Arikan S, Karatepe O, Kemik O, Ayhan S, Karaoz E, et al. Mesenchymal stem cells improve the healing of ischemic colonic anastomoses (experimental study). Langenbecks Arch Surg. 2011;396:115-26 pubmed 出版商
  • 免疫组化; 人类; 1:100
Cardoso C, Bornstein S, Hornsby P. Optimizing orthotopic cell transplantation in the mouse adrenal gland. Cell Transplant. 2010;19:565-72 pubmed 出版商
  • 免疫组化; 小鼠
Jiang Z, Belforte J, Lu Y, Yabe Y, Pickel J, Smith C, et al. eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation. J Neurosci. 2010;30:2582-94 pubmed 出版商
  • 免疫组化; 人类; 1:200
Bai Y, Du L, Shen L, Zhang Y, Zhang L. GPR56 is highly expressed in neural stem cells but downregulated during differentiation. Neuroreport. 2009;20:918-22 pubmed 出版商
  • 免疫组化; 小鼠
Fitzgerald D, Cole S, Hammond A, Seaman C, Cooper H. Characterization of neogenin-expressing neural progenitor populations and migrating neuroblasts in the embryonic mouse forebrain. Neuroscience. 2006;142:703-16 pubmed
  • 免疫组化; 人类; 1:200
Garbelli R, Meroni A, Magnaghi G, Beolchi M, Ferrario A, Tassi L, et al. Architectural (Type IA) focal cortical dysplasia and parvalbumin immunostaining in temporal lobe epilepsy. Epilepsia. 2006;47:1074-8 pubmed
  • 免疫细胞化学; 大鼠; 1:200
Xu X, He C, Zhang Z, Chen Y. MKLP1 requires specific domains for its dendritic targeting. J Cell Sci. 2006;119:452-8 pubmed
  • 免疫细胞化学; 人类
Denham M, Huynh T, Dottori M, Allen G, Trounson A, Mollard R. Neural stem cells express non-neural markers during embryoid body coculture. Stem Cells. 2006;24:918-27 pubmed
  • 免疫细胞化学; African green monkey; 1:400
Hu Q, Saegusa H, Hayashi Y, Tanabe T. The carboxy-terminal tail region of human Cav2.1 (P/Q-type) channel is not an essential determinant for its subcellular localization in cultured neurones. Genes Cells. 2005;10:87-96 pubmed
  • 流式细胞仪; 人类; 1:100
  • 免疫细胞化学; 人类; 1:100
Li X, Xu J, Bai Y, Wang X, Dai X, Liu Y, et al. Isolation and characterization of neural stem cells from human fetal striatum. Biochem Biophys Res Commun. 2005;326:425-34 pubmed
Li C, Coffey E, Dall Agnese A, Hannett N, Tang X, Henninger J, et al. MeCP2 links heterochromatin condensates and neurodevelopmental disease. Nature. 2020;586:440-444 pubmed 出版商
Le Large T, El Hassouni B, Funel N, Kok B, Piersma S, Pham T, et al. Proteomic analysis of gemcitabine-resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment. Ther Adv Med Oncol. 2019;11:1758835919841233 pubmed 出版商
Karaoz E, Tepekoy F, Yılmaz I, Subasi C, Kabatas S. Reduction of Inflammation and Enhancement of Motility after Pancreatic Islet Derived Stem Cell Transplantation Following Spinal Cord Injury. J Korean Neurosurg Soc. 2019;62:153-165 pubmed 出版商
Schmidt M, Buren C, Mackay J, Cheung D, Dal Cengio L, Raymond L, et al. Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease. BMC Biol. 2018;16:58 pubmed 出版商
Tsutsui K, Grabenhorst F, Kobayashi S, Schultz W. A dynamic code for economic object valuation in prefrontal cortex neurons. Nat Commun. 2016;7:12554 pubmed 出版商
Karaoz E, Kabatas S, Duruksu G, Okçu A, Subasi C, Ay B, et al. Reduction of lesion in injured rat spinal cord and partial functional recovery of motility after bone marrow derived mesenchymal stem cell transplantation. Turk Neurosurg. 2012;22:207-17 pubmed 出版商
Marcinkiewicz M. BetaAPP and furin mRNA concentrates in immature senile plaques in the brain of Alzheimer patients. J Neuropathol Exp Neurol. 2002;61:815-29 pubmed
Lin S, Constantine Paton M. Suppression of sprouting: An early function of NMDA receptors in the absence of AMPA/kainate receptor activity. J Neurosci. 1998;18:3725-37 pubmed
图像
图像 1 :
赛默飞世尔 MA5-12823 图像 1
Formalin-fixed, paraffin-embedded human brain stained with Microtubulessociated Protein 2a,b antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of the neurons and dendrites.
产品信息
产品类型 :
抗体
产品名称 :
微管相关蛋白2单克隆抗体(AP20)
目录# :
MA5-12823
规格 :
500微升
价格 :
美国446.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
牛, 人类
应用 :
Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:100-200, Western Blot: 1:20-50
物种 :
牛, 人类
克隆 :
AP20
抗体亚型 :
IgG1
储存 :
4° C
描述 :
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).
免疫原 :
牛大脑微管相关蛋白2
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:100-200, Western Blot: 1:20-50
别名 :
a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国