产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
微管相关蛋白2单克隆抗体(AP18)
目录 :
MA5-12826
规格 :
500微升
价格 :
美国447.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AP18
反应物种 :
豚鼠, 人类, 小鼠, 大鼠, 犬, 牛, 非洲爪蛙
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 30
| 出版应用/物种/样本/稀释 | 参考文献 |
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| Raso A, Negri F, Gregorio A, Nozza P, Mascelli S, De Marco P, et al. Successful isolation and long-term establishment of a cell line with stem cell-like features from an anaplastic medulloblastoma. Neuropathol Appl Neurobiol. 2008;34:306-15 pubmed
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| van Vliet E, Stoppini L, Balestrino M, Eskes C, Griesinger C, Sobanski T, et al. Electrophysiological recording of re-aggregating brain cell cultures on multi-electrode arrays to detect acute neurotoxic effects. Neurotoxicology. 2007;28:1136-46 pubmed
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| Mitsui S, Yamaguchi N, Osako Y, Yuri K. Enzymatic properties and localization of motopsin (PRSS12), a protease whose absence causes mental retardation. Brain Res. 2007;1136:1-12 pubmed
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| Tian G, Lai L, Guo H, Lin Y, Butchbach M, Chang Y, et al. Translational control of glial glutamate transporter EAAT2 expression. J Biol Chem. 2007;282:1727-37 pubmed
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| Chen J, Tseng H, Dichter M, Zhang H, Greene M. Differential localization of ErbB receptor ensembles influences their signaling in hippocampal neurons. DNA Cell Biol. 2005;24:553-62 pubmed
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| Kan R, Pleva C, Hamilton T, Petrali J. Immunolocalization of MAP-2 in routinely formalin-fixed, paraffin-embedded guinea pig brain sections using microwave irradiation: a comparison of different combinations of antibody clones and antigen retrieval buffer solutions. Microsc Microanal. 2005;11:175-80 pubmed
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Zurich M, Honegger P, Schilter B, Costa L, Monnet Tschudi F. Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos. Toxicol Appl Pharmacol. 2004;201:97-104 pubmed
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Wang Y, Bai Y, Li X, Hu Q, Lin C, Xiao Z, et al. Fetal human neural progenitors can be the target for tumor transformation. Neuroreport. 2004;15:1907-12 pubmed
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Eskes C, Juillerat Jeanneret L, Leuba G, Honegger P, Monnet Tschudi F. Involvement of microglia-neuron interactions in the tumor necrosis factor-alpha release, microglial activation, and neurodegeneration induced by trimethyltin. J Neurosci Res. 2003;71:583-90 pubmed
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Farah C, Nguyen M, Julien J, Leclerc N. Altered levels and distribution of microtubule-associated proteins before disease onset in a mouse model of amyotrophic lateral sclerosis. J Neurochem. 2003;84:77-86 pubmed
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Dobashi Y, Shoji M, Kitagawa M, Noguchi T, Kameya T. Simultaneous suppression of cdc2 and cdk2 activities induces neuronal differentiation of PC12 cells. J Biol Chem. 2000;275:12572-80 pubmed
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Lin S, Constantine Paton M. Suppression of sprouting: An early function of NMDA receptors in the absence of AMPA/kainate receptor activity. J Neurosci. 1998;18:3725-37 pubmed
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图像
图像 1 :
Immunofluorescent analysis of MAP2 a,b,c (green) in SH-SY5Y cells either left untreated (left panel) or treated with 10uM all-trans retinoic acid for 72 hours (right panel). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA (Product # 37525) for 15 minutes at room temperature. Cells were probed with a MAP2 a,b,c monoclonal antibody (Product # MA5-12826) at a dilution of 1:200 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488 goat anti-mouse IgG secondary antibody (Product # 35502) at a dilution of 1:400 for 30 minutes at room temperature. F-Actin (red) was stained with DyLight 554 Phalloidin (Product # 21834) and nuclei (blue) were stained with Hoechst 33342 dye (Product # 62249). Images were taken on a Thermo Scientific ArrayScan or a ToxInsight Instrument at 20X magnification.
图像 2 :
Formalin-fixed, paraffin-embedded rat brain stained with MAP antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of neurons and fibers.
图像 3 :
产品信息
产品类型 :
抗体
产品名称 :
微管相关蛋白2单克隆抗体(AP18)
目录# :
MA5-12826
规格 :
500微升
价格 :
美国447.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
Avian, Bovine, Human, Mouse, Rat, Xenopus laevis
应用 :
Immunocytochemistry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1-2 µg/mL
物种 :
Avian, Bovine, Human, Mouse, Rat, Xenopus laevis
克隆 :
AP18
抗体亚型 :
IgG1
储存 :
4° C
描述 :
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).
免疫原 :
牛大脑微管相关蛋白2
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1-2 µg/mL
别名 :
a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2
更多信息或购买 :
公司信息
赛默飞世尔