产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
RPSA单克隆抗体(MLuC5)
目录 :
MA5-12840
规格 :
500微升
价格 :
美国408.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MLuC5
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 12
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Wang Q, Wang H, Li Y, Xie Z, Ma Y, Yan J, et al. Inhibition of EMMPRIN and MMP-9 Expression by Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor in PMA-Induced Macrophages. Cell Physiol Biochem. 2016;39:2308-2319 pubmed
|
| |
| |
| |
| |
| |
| |
| |
| |
| Branca M, Giorgi C, Ciotti M, Santini D, Di Bonito L, Costa S, et al. Relationship of up-regulation of 67-kd laminin receptor to grade of cervical intraepithelial neoplasia and to high-risk HPV types and prognosis in cervical cancer. Acta Cytol. 2006;50:6-15 pubmed
|
Christie P, Jonas M, Tsai C, Chi E, Henderson W. Increase in laminin expression in allergic airway remodelling and decrease by dexamethasone. Eur Respir J. 2004;24:107-15 pubmed
| |
Ganor Y, Besser M, Ben Zakay N, Unger T, Levite M. Human T cells express a functional ionotropic glutamate receptor GluR3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and chemotactic migration. J Immunol. 2003;170:4362-72 pubmed
|
图像
图像 1 :
Formalin-fixed, paraffin-embedded human breast carcinoma stained with Laminin Receptor antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane with some cytoplasmic staining of tumor cells.
产品信息
产品类型 :
抗体
产品名称 :
RPSA单克隆抗体(MLuC5)
目录# :
MA5-12840
规格 :
500微升
价格 :
美国408.00
克隆性 :
单克隆
纯度 :
硫酸铵沉淀
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 4-8 µg/mL, Western Blot: 1:10-1:200
物种 :
人类
克隆 :
MLuC5
抗体亚型 :
IgM
储存 :
4° C
描述 :
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
免疫原 :
Small cell lung carcinoma N592 live cells
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 4-8 µg/mL, Western Blot: 1:10-1:200
别名 :
37 kDa laminin receptor; 37 kDa laminin receptor precursor; 37 kDa laminin receptor precursor {ECO:0000255; 37 kDa oncofetal antigen; 37/67 kDa laminin receptor; 37/67 kDa laminin receptor {ECO:0000255; 37LRP; 37LRP {ECO:0000255; 40S ribosomal protein SA; 40S ribosomal protein SA {ECO:0000255; 67 kDa laminin receptor; 67 kDa laminin receptor {ECO:0000255; 67kDa; 67LR; 67LR {ECO:0000255; AL022858; colon carcinoma laminin-binding protein; HAMAP-Rule:MF_03016}; ICAS; LAMBR; Laminin receptor 1; laminin receptor 1 (67kD, ribosomal protein SA); laminin receptor 1 (ribosomal protein SA); laminin receptor 1 {ECO:0000255; laminin-binding protein precursor p40; laminin-binding protein precursor p40 {ECO:0000255; LamR; lamR {ECO:0000255; LAMR1; Lamrl1; LBP; LBP/p40; LBP/p40 {ECO:0000255; LRP; LRP/LR; LRP/LR {ECO:0000255; MLR; Multidrug resistance-associated protein MGr1-Ag; NEM/1CHD4; OFA/iLRP; p40; P40-3; P40-3, functional; P40-8; P40-8, functional; ribosomal protein SA; Rpsa; rssa; SA; Small ribosomal subunit protein uS2
更多信息或购买 :
公司信息
赛默飞世尔