产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Prohibitin Monoclonal Antibody (II-14-10), Biotin
目录 :
MA5-12855
规格 :
500微升
价格 :
美国508.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
生物素
克隆名称 :
II-14-10
反应物种 :
人类, 小鼠, 大鼠, 鸡, 牛, pigs , 肝炎病毒C
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀
, 免疫组化-石蜡切片
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文章摘录数: 56
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| Jiang P, Xiang Y, Wang Y, Li S, Wang Y, Hua H, et al. Differential expression and subcellular localization of Prohibitin 1 are related to tumorigenesis and progression of non-small cell lung cancer. Int J Clin Exp Pathol. 2013;6:2092-101 pubmed
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| Leanza L, Zoratti M, Gulbins E, Szabo I. Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels. Curr Med Chem. 2012;19:5394-404 pubmed
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| Shi S, Li Q, Liu Q, Xu D, Tang J, Liang Y, et al. Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT). J Cell Biochem. 2009;108:926-34 pubmed 出版商
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| Sikora J, Dvorakova L, Vlaskova H, Stolnaja L, Betlach J, Spacek J, et al. A case of excessive autophagocytosis with multiorgan involvement and low clinical penetrance. Cesk Patol. 2007;43:93-103 pubmed
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| Wu T, Wu H, Wang Y, Chang T, Chan S, Lin Y, et al. Prohibitin in the pathogenesis of transitional cell bladder cancer. Anticancer Res. 2007;27:895-900 pubmed
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| Chuang Y, Chen S, Lin T, Liou C, Chang W, Chan S, et al. Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat. Neuropharmacology. 2007;52:1263-73 pubmed
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| Chan J, Cheng H, Chou J, Li F, Dai K, Chan S, et al. Heat shock protein 60 or 70 activates nitric-oxide synthase (NOS) I- and inhibits NOS II-associated signaling and depresses the mitochondrial apoptotic cascade during brain stem death. J Biol Chem. 2007;282:4585-600 pubmed
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| Pucci B, Adams C, Fertala J, Snyder B, Mansfield K, Tafani M, et al. Development of the terminally differentiated state sensitizes epiphyseal chondrocytes to apoptosis through caspase-3 activation. J Cell Physiol. 2007;210:609-15 pubmed
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| Guo W, Xu H, Chen J, Yang Y, Jin J, Fu R, et al. Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1. Mol Cell Biochem. 2007;295:167-77 pubmed
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| Sikora J, Harzer K, Elleder M. Neurolysosomal pathology in human prosaposin deficiency suggests essential neurotrophic function of prosaposin. Acta Neuropathol. 2007;113:163-75 pubmed
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| Joshi B, Rastogi S, Morris M, Carastro L, DeCook C, Seto E, et al. Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites. Biochem J. 2007;401:155-66 pubmed
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| Tsintzas K, Jewell K, Kamran M, Laithwaite D, Boonsong T, Littlewood J, et al. Differential regulation of metabolic genes in skeletal muscle during starvation and refeeding in humans. J Physiol. 2006;575:291-303 pubmed
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| Chang A, Chan J, Chou J, Li F, Dai K, Chan S. Heat shock protein 60 in rostral ventrolateral medulla reduces cardiovascular fatality during endotoxaemia in the rat. J Physiol. 2006;574:547-64 pubmed
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| Chan H, Gharbi S, Gaffney P, Cramer R, Waterfield M, Timms J. Proteomic analysis of redox- and ErbB2-dependent changes in mammary luminal epithelial cells using cysteine- and lysine-labelling two-dimensional difference gel electrophoresis. Proteomics. 2005;5:2908-26 pubmed
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| Suzuki R, Sakamoto S, Tsutsumi T, Rikimaru A, Tanaka K, Shimoike T, et al. Molecular determinants for subcellular localization of hepatitis C virus core protein. J Virol. 2005;79:1271-81 pubmed
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| Li Q, Ching A, Chan B, Chow S, Lim P, Ho T, et al. A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway. J Biol Chem. 2004;279:52106-16 pubmed
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Ullmann R, Morbini P, Halbwedl I, Bongiovanni M, Gogg Kammerer M, Papotti M, et al. Protein expression profiles in adenocarcinomas and squamous cell carcinomas of the lung generated using tissue microarrays. J Pathol. 2004;203:798-807 pubmed
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Thompson W, Ramalho Santos J, Sutovsky P. Ubiquitination of prohibitin in mammalian sperm mitochondria: possible roles in the regulation of mitochondrial inheritance and sperm quality control. Biol Reprod. 2003;69:254-60 pubmed
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图像
图像 1 :
Formalin-fixed, paraffin-embedded human heart stained with Prohibitin antibody using peroxidase-conjugate and DAB chromogen.
图像 2 :
Formalin-fixed, paraffin-embedded rat heart stained with Prohibitin antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of cardiac muscles.
产品信息
产品类型 :
抗体
产品名称 :
Prohibitin Monoclonal Antibody (II-14-10), Biotin
目录# :
MA5-12855
规格 :
500微升
价格 :
美国508.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
Chicken, Human, Mouse, Non-human primate, Porcine, Rat
应用 :
Immunohistochemistry (Paraffin): 2-4 µg/mL, Western Blot: 0.5-1.0 µg/mL
物种 :
Chicken, Human, Mouse, Non-human primate, Porcine, Rat
克隆 :
II-14-10
抗体亚型 :
IgG1
储存 :
4° C
描述 :
Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
免疫原 :
Purified recombinant rat prohibitin protein
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 2-4 µg/mL, Western Blot: 0.5-1.0 µg/mL
别名 :
BAP 32; Bap32; B-cell receptor-associated protein 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; fa18f07; fb09f05; HEL-215; HEL-S-54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; PHB; phb protein; PHB1; Prohibitin; sr:nyz128; wu:fa18f07; wu:fb09f05
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公司信息
赛默飞世尔