产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD20单克隆抗体(L26)
目录 :
MA5-13141
规格 :
500微升
价格 :
美国472
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
L26
反应物种 :
marmosets, 人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 72
出版应用/物种/样本/稀释 | 参考文献 |
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| Chamberland F, Maurina T, Degano Valmary S, Spicarolen T, Chaigneau L. Angiosarcoma: A Case Report of Gingival Disease with Both Palatine Tonsils Localization. Rare Tumors. 2016;8:5907 pubmed
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| van den Brand M, Balagué O, van Cleef P, Groenen P, Hebeda K, de Jong D, et al. A subset of low-grade B cell lymphomas with a follicular growth pattern but without a BCL2 translocation shows features suggestive of nodal marginal zone lymphoma. J Hematop. 2016;9:3-8 pubmed
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| Yang Y, Li Y, Liu Y, Yang M, Liu K. CD30+ extranodal natural killer/T-cell lymphoma mimicking phlegmonous myositis: A case report. Oncol Lett. 2014;7:1419-1421 pubmed
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| Mártha K, Mezei T, Jánosi K. A histological analysis of gingival condition associated with orthodontic treatment. Rom J Morphol Embryol. 2013;54:823-7 pubmed
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| Tokatli F, Puyan F, Alas R, Tuncbilek N, Uzal C. Extramedullary plasmacytoma: clinicopathology, immunohistochemistry and therapeutic approach to a case with a tonsillar site. Hematol Oncol Stem Cell Ther. 2008;1:241-5 pubmed
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| Zurac S, Girtan M, Lavric L, Petsakos G, Staniceanu F, Bastian A, et al. Local immune alterations in oral mucosa of the edentulous patients; possible cause of teeth loss?. Rom J Intern Med. 2008;46:249-53 pubmed
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| Belousova I, Vanecek T, Samtsov A, Michal M, Kazakov D. A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: report of a case and comparative retrospective study of 27 cases of "nonprogressive" small plaque parapsoriasis. J Am Acad Dermatol. 2008;59:474-82 pubmed 出版商
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| Kazakov D, Belousova I, Kacerovska D, Sima R, Vanecek T, Vazmitel M, et al. Hyperplasia of hair follicles and other adnexal structures in cutaneous lymphoproliferative disorders: a study of 53 cases, including so-called pseudolymphomatous folliculitis and overt lymphomas. Am J Surg Pathol. 2008;32:1468-78 pubmed 出版商
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| van der Loos C. Multiple immunoenzyme staining: methods and visualizations for the observation with spectral imaging. J Histochem Cytochem. 2008;56:313-28 pubmed
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| Boudova L, Kazakov D, Jindra P, Sima R, Vanecek T, Kuntscher V, et al. Primary cutaneous histiocyte and neutrophil-rich CD30+ and CD56+ anaplastic large-cell lymphoma with prominent angioinvasion and nerve involvement in the forehead and scalp of an immunocompetent woman. J Cutan Pathol. 2006;33:584-9 pubmed
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| Kostopoulos I, Cocco M, Ginanneschi C, D Amuri A, Lazzi S, Fabbri A, et al. Overlapping morphologic and immunophenotypic profiles in small B-cell lymphoma. A report of two cases. Virchows Arch. 2006;449:320-7 pubmed
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| Avninder S, Sharma M, Deb P, Mehta V, Karak A, Mahapatra A, et al. Gemistocytic astrocytomas: histomorphology, proliferative potential and genetic alterations--a study of 32 cases. J Neurooncol. 2006;78:123-7 pubmed
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| Cattoretti G, Büttner M, Shaknovich R, Kremmer E, Alobeid B, Niedobitek G. Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells. Blood. 2006;107:3967-75 pubmed
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| Boudova L, Kazakov D, Sima R, Vanecek T, Torlakovic E, Lamovec J, et al. Cutaneous lymphoid hyperplasia and other lymphoid infiltrates of the breast nipple: a retrospective clinicopathologic study of fifty-six patients. Am J Dermatopathol. 2005;27:375-86 pubmed
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| Gucer F, Altaner S, Mulayim N, Yapicier O. Invasive inflammatory pseudotumor of uterine cervix: a case report. Gynecol Oncol. 2005;98:325-8 pubmed
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| Grois N, Prayer D, Prosch H, Lassmann H. Neuropathology of CNS disease in Langerhans cell histiocytosis. Brain. 2005;128:829-38 pubmed
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| Lazuardi L, Jenewein B, Wolf A, Pfister G, Tzankov A, Grubeck Loebenstein B. Age-related loss of naïve T cells and dysregulation of T-cell/B-cell interactions in human lymph nodes. Immunology. 2005;114:37-43 pubmed
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Takahashi D, Kojima M, Suzuki T, Sugimoto M, Kobayashi S, Takahashi S, et al. Profiling the Tumour Immune Microenvironment in Pancreatic Neuroendocrine Neoplasms with Multispectral Imaging Indicates Distinct Subpopulation Characteristics Concordant with WHO 2017 Classification. Sci Rep. 2018;8:13166 pubmed 出版商
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Jain D, Sharma M, Sarkar C, Deb P, Gupta D, Mahapatra A. Correlation of diagnostic yield of stereotactic brain biopsy with number of biopsy bits and site of the lesion. Brain Tumor Pathol. 2006;23:71-5 pubmed
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Nielsen C, Williams J, van den Brink G, Lauwers G, Roberts D. Hh pathway expression in human gut tissues and in inflammatory gut diseases. Lab Invest. 2004;84:1631-42 pubmed
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Ku C, Zerboni L, Ito H, Graham B, Wallace M, Arvin A. Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alpha. J Exp Med. 2004;200:917-25 pubmed
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Tani K, Azuma M, Nakazaki Y, Oyaizu N, Hase H, Ohata J, et al. Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings. Mol Ther. 2004;10:799-816 pubmed
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Wang W, Bergh A, Damber J. Chronic inflammation in benign prostate hyperplasia is associated with focal upregulation of cyclooxygenase-2, Bcl-2, and cell proliferation in the glandular epithelium. Prostate. 2004;61:60-72 pubmed
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Bellan C, De Falco G, Lazzi S, Micheli P, Vicidomini S, Schurfeld K, et al. CDK9/CYCLIN T1 expression during normal lymphoid differentiation and malignant transformation. J Pathol. 2004;203:946-52 pubmed
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Oz Puyan F, Bilgi S, Unlu E, Yalcin O, Altaner S, Demir M, et al. Inflammatory pseudotumor of the spleen with EBV positivity: report of a case. Eur J Haematol. 2004;72:285-91 pubmed
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Aki H, Tuzuner N, Ongoren S, Baslar Z, Soysal T, Ferhanoglu B, et al. T-cell-rich B-cell lymphoma: a clinicopathologic study of 21 cases and comparison with 43 cases of diffuse large B-cell lymphoma. Leuk Res. 2004;28:229-36 pubmed
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Demetter P, Van Huysse J, De Keyser F, Van Damme N, Verbruggen G, Mielants H, et al. Increase in lymphoid follicles and leukocyte adhesion molecules emphasizes a role for the gut in spondyloarthropathy pathogenesis. J Pathol. 2002;198:517-22 pubmed
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图像
图像 1 :
Formalin-fixed, paraffin-embedded human tonsil stained with CD20 antibody using alkaline phosphatase-conjugate and fast red chromogen. Note cell membrane staining of B lymphocytes.
产品信息
产品类型 :
抗体
产品名称 :
CD20单克隆抗体(L26)
目录# :
MA5-13141
规格 :
500微升
价格 :
美国472
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 1:2, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:250, Western Blot: 1:1,000-1:5,000
物种 :
人类
克隆 :
L26
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation. CD20 is expressed on mature and most malignant B cells, in a subpopulation of T lymphocytes and follicular dendritic cells. CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation. CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation. After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface. CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell malignancies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment. Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.
免疫原 :
人类扁桃体B细胞
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:2, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:250, Western Blot: 1:1,000-1:5,000
别名 :
AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7
更多信息或购买 :
公司信息
赛默飞世尔