产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
血管内皮生长因子单克隆抗体(JH121)
目录 :
MA5-13182
规格 :
500微升
价格 :
美国419
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
JH121
反应物种 :
人类, 小鼠, 大鼠, 犬, 牛, domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 109
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:250–1:500
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed 出版商
  • 免疫组化-石蜡切片; 犬; 1:100; 图 1
Carvalho M, Pires I, Prada J, Raposo T, Gregório H, Lobo L, et al. High COX-2 expression is associated with increased angiogenesis, proliferation and tumoural inflammatory infiltrate in canine malignant mammary tumours: a multivariate survival study. Vet Comp Oncol. 2017;15:619-631 pubmed 出版商
  • 免疫组化-石蜡切片; 犬; 1:100
Carvalho M, Pires I, Dias M, Prada J, Gregório H, Lobo L, et al. Intratumoral CD3+ T-lymphocytes immunoexpression and its association with c-Kit, angiogenesis, and overall survival in malignant canine mammary tumors. Anal Cell Pathol (Amst). 2015;2015:920409 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Jung S, Sielker S, Purcz N, Sproll C, Acil Y, Kleinheinz J. Analysis of angiogenic markers in oral squamous cell carcinoma-gene and protein expression. Head Face Med. 2015;11:19 pubmed 出版商
  • 免疫组化; 人类; 1:50
Lattanzio R, La Sorda R, Facciolo F, Sioletic S, Lauriola L, Martucci R, et al. Thymic epithelial tumors express vascular endothelial growth factors and their receptors as potential targets of antiangiogenic therapy: a tissue micro array-based multicenter study. Lung Cancer. 2014;85:191-6 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:150
Quintas H, Alegría N, Mendonça A, Botelho A, Alves A, Pires I. Coexistence of tuberculosis and mammary carcinoma in a goat. Reprod Domest Anim. 2014;49:606-610 pubmed 出版商
  • 免疫组化; domestic rabbit; 1:50
Kadar T, Amir A, Cohen L, Cohen M, Sahar R, Gutman H, et al. Anti-VEGF therapy (bevacizumab) for sulfur mustard-induced corneal neovascularization associated with delayed limbal stem cell deficiency in rabbits. Curr Eye Res. 2014;39:439-50 pubmed 出版商
  • 免疫组化; 人类
El Behery M, Seksaka M, Ibrahiem M, Saleh H, El Alfy Y. Clinicopathological correlation of endocan expression and survival in epithelial ovarian cancer. Arch Gynecol Obstet. 2013;288:1371-6 pubmed 出版商
  • 免疫组化; 人类; 1:100
Shimoda Y, Ogawa Y, Watanabe M, Tominaga T. Clinicopathological investigation of vascular endothelial growth factor and von Hippel-Lindau gene-related protein expression in immunohistochemically negative pituitary adenoma--possible involvement in tumor aggressiveness. Endocr Res. 2013;38:242-50 pubmed 出版商
  • 免疫组化; domestic rabbit; 1:50
Shi Y, Xu T, Li L, Chen X. Over-expression of VEGF and MMP-9 in residual tumor cells of hepatocellular carcinoma after embolization with lipidol. J Huazhong Univ Sci Technolog Med Sci. 2013;33:90-95 pubmed 出版商
  • 免疫组化; 人类; 1:100
Mitra A, Castelao J, Hawes D, Tsao Wei D, Jiang X, Shi S, et al. Combination of molecular alterations and smoking intensity predicts bladder cancer outcome: a report from the Los Angeles Cancer Surveillance Program. Cancer. 2013;119:756-65 pubmed 出版商
  • 免疫组化; 人类; 1:50
Karetsi E, Ioannou M, Kerenidi T, Minas M, Molyvdas P, Gourgoulianis K, et al. Differential expression of hypoxia-inducible factor 1α in non-small cell lung cancer and small cell lung cancer. Clinics (Sao Paulo). 2012;67:1373-8 pubmed
  • 免疫组化; 人类; 1:20
Pardo J, Panizo A, Sola I, Queipo F, Martínez Peñuela A, Carias R. Prognostic value of clinical, morphologic, and immunohistochemical factors in patients with bronchiolitis obliterans-organizing pneumonia. Hum Pathol. 2013;44:718-24 pubmed 出版商
  • 免疫组化; 人类; 1:50
Mitselou A, Skoufi U, Tsimogiannis K, Briasoulis E, Vougiouklakis T, Arvanitis D, et al. Association of syndecan-1 with angiogenesis-related markers, extracellular matrix components, and clinicopathological features in colorectal carcinoma. Anticancer Res. 2012;32:3977-85 pubmed
  • 免疫细胞化学; 人类
  • 免疫组化; 人类
Hu Y, Kong S, Kong H, Wu J, Chen Z. Targeting c-Myc on cell growth and vascular endothelial growth factor expression in IN500 glioblastoma cells. Chin Med J (Engl). 2012;125:2025-31 pubmed
  • 免疫组化; 人类
Piccolo E, Tinari N, Semeraro D, Traini S, Fichera I, Cumashi A, et al. LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesis. J Mol Med (Berl). 2013;91:83-94 pubmed 出版商
  • 免疫组化; 人类; 1:50
Al Salam S, Balalaa N, Faour I, Akhter S, Alashari M. HIF-1?, VEGF and WT-1 are protagonists in bilateral primary angiosarcoma of breast: a case report and review of literature. Int J Clin Exp Pathol. 2012;5:247-53 pubmed
  • 免疫组化; 人类
Kovacs J, Gurzu S, Jung J, Szederjesi J, Copotoiu S, Copotoiu R, et al. Clinico-pathological particularities of the shock-related pancreatitis. Pathol Oncol Res. 2012;18:977-81 pubmed
  • 免疫组化-石蜡切片; 人类; 1:50
Jung Y, Joo K, Seong D, Choi Y, Kong D, Kim Y, et al. Identification of prognostic biomarkers for glioblastomas using protein expression profiling. Int J Oncol. 2012;40:1122-32 pubmed 出版商
  • 免疫组化; 人类; 1:50
Radhakrishnan V, Kashyap S, Singh L, Bakhshi S. VEGF expression in residual tumor cells in orbital retinoblastoma (IRSS stage III) treated with NACT: a prospective study. Pediatr Blood Cancer. 2012;59:567-9 pubmed 出版商
  • 免疫组化; 人类
Takagi Y, Kikuta K, Moriwaki T, Aoki T, Nozaki K, Hashimoto N, et al. Expression of thioredoxin-1 and hypoxia inducible factor-1? in cerebral arteriovenous malformations: Possible role of redox regulatory factor in neoangiogenic property. Surg Neurol Int. 2011;2:61 pubmed 出版商
  • 免疫细胞化学; 人类
Battinelli E, Markens B, Italiano J. Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis. Blood. 2011;118:1359-69 pubmed 出版商
  • 免疫组化; domestic rabbit
Yoshida K, Hirokawa T, Moriyasu F, Liu L, Liu G, Yamada M, et al. Arterial-phase contrast-enhanced ultrasonography for evaluating anti-angiogenesis treatment: a pilot study. World J Gastroenterol. 2011;17:1045-50 pubmed 出版商
  • 免疫组化; domestic rabbit; 1:50
Zheng L, Li Y, Wang H, Zhao J, Wang X, Hu Y, et al. Combination of vascular endothelial growth factor antisense oligonucleotide therapy and radiotherapy increases the curative effects against maxillofacial VX2 tumors in rabbits. Eur J Radiol. 2011;78:272-6 pubmed 出版商
  • 免疫组化; 人类; 1:100
Yoshinaga K, Ito K, Moriya T, Nagase S, Takano T, Niikura H, et al. Roles of intrinsic angiogenesis inhibitor, vasohibin, in cervical carcinomas. Cancer Sci. 2011;102:446-51 pubmed 出版商
  • 免疫组化; 人类; 1:50
Brunner A, Grimm C, Polterauer S, Hefler L, Stani J, Dudek G, et al. Expression of epidermal growth factor receptor and vascular endothelial growth factor in vaginal squamous cell cancer. Am J Obstet Gynecol. 2011;204:171.e1-6 pubmed 出版商
  • 免疫组化; 人类
Wu Y, Jin M, Xu H, Shimin Z, He S, Wang L, et al. Clinicopathologic significance of HIF-1?, CXCR4, and VEGF expression in colon cancer. Clin Dev Immunol. 2010;2010: pubmed 出版商
  • 免疫组化; 人类; 1:150
Queiroga F, Pires I, Parente M, Gregório H, Lopes C. COX-2 over-expression correlates with VEGF and tumour angiogenesis in canine mammary cancer. Vet J. 2011;189:77-82 pubmed 出版商
  • 免疫组化; 人类
Azamfirei L, Gurzu S, Solomon R, Copotoiu R, Copotoiu S, Jung I, et al. Vascular endothelial growth factor: a possible mediator of endothelial activation in acute respiratory distress syndrome. Minerva Anestesiol. 2010;76:609-16 pubmed
  • 免疫组化; 人类
Maderna E, Corsini E, Franzini A, Giombini S, Pollo B, Broggi G, et al. Expression of vascular endothelial growth factor receptor-1/-2 and nitric oxide in unruptured intracranial aneurysms. Neurol Sci. 2010;31:617-23 pubmed 出版商
  • 免疫组化; 人类
Zhang C, Hao L, Wang L, Xiao Y, Ge H, Zhu Z, et al. Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node metastasis in human colorectal cancer. BMC Cancer. 2010;10:184 pubmed 出版商
  • 免疫组化; 人类; 1:50
  • 免疫印迹; 人类
Harikumar K, Kunnumakkara A, Sethi G, Diagaradjane P, Anand P, Pandey M, et al. Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer. Int J Cancer. 2010;127:257-68 pubmed 出版商
  • 抑制或激活实验; 大鼠
Johansson A, Olerud J, Johansson M, Carlsson P. Angiostatic factors normally restrict islet endothelial cell proliferation and migration: implications for islet transplantation. Transpl Int. 2009;22:1182-8 pubmed
  • 免疫组化; 人类
van der Loos C, Meijer Jorna L, Broekmans M, Ploegmakers H, Teeling P, de Boer O, et al. Anti-human vascular endothelial growth factor (VEGF) antibody selection for immunohistochemical staining of proliferating blood vessels. J Histochem Cytochem. 2010;58:109-18 pubmed 出版商
  • 免疫组化; 人类; 1:50
Ioannou M, Papamichali R, Kouvaras E, Mylonis I, Vageli D, Kerenidou T, et al. Hypoxia inducible factor-1 alpha and vascular endothelial growth factor in biopsies of small cell lung carcinoma. Lung. 2009;187:321-9 pubmed 出版商
  • 免疫组化; 人类
Khotskaya Y, Dai Y, Ritchie J, Macleod V, Yang Y, Zinn K, et al. Syndecan-1 is required for robust growth, vascularization, and metastasis of myeloma tumors in vivo. J Biol Chem. 2009;284:26085-95 pubmed 出版商
  • 免疫组化; 人类; 1:1000
Hosaka T, Kimura H, Heishi T, Suzuki Y, Miyashita H, Ohta H, et al. Vasohibin-1 expression in endothelium of tumor blood vessels regulates angiogenesis. Am J Pathol. 2009;175:430-9 pubmed 出版商
  • 免疫组化; 人类; 1:50
Bonnesen B, Pappot H, Holmstav J, Skov B. Vascular endothelial growth factor A and vascular endothelial growth factor receptor 2 expression in non-small cell lung cancer patients: relation to prognosis. Lung Cancer. 2009;66:314-8 pubmed 出版商
  • 抑制或激活实验; 人类; 10 ug/ml
Lolmede K, Campana L, Vezzoli M, Bosurgi L, Tonlorenzi R, Clementi E, et al. Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways. J Leukoc Biol. 2009;85:779-87 pubmed 出版商
  • 免疫组化; 人类; 1:80
Smith V, Wirth G, Fiebig H, Burger A. Tissue microarrays of human tumor xenografts: characterization of proteins involved in migration and angiogenesis for applications in the development of targeted anticancer agents. Cancer Genomics Proteomics. 2008;5:263-73 pubmed
  • 抑制或激活实验; 大鼠
Tolstanova G, Khomenko T, Deng X, Chen L, Tarnawski A, Ahluwalia A, et al. Neutralizing anti-vascular endothelial growth factor (VEGF) antibody reduces severity of experimental ulcerative colitis in rats: direct evidence for the pathogenic role of VEGF. J Pharmacol Exp Ther. 2009;328:749-57 pubmed 出版商
  • 免疫组化; 人类; 1:50
Alkim C, Savas B, Ensari A, Alkim H, Dagli U, Parlak E, et al. Expression of p53, VEGF, microvessel density, and cyclin-D1 in noncancerous tissue of inflammatory bowel disease. Dig Dis Sci. 2009;54:1979-84 pubmed 出版商
  • 免疫组化; 人类
Arbab A, Janic B, Knight R, Anderson S, Pawelczyk E, Rad A, et al. Detection of migration of locally implanted AC133+ stem cells by cellular magnetic resonance imaging with histological findings. FASEB J. 2008;22:3234-46 pubmed 出版商
  • 免疫组化; 人类
Huynh H, Chow P, Palanisamy N, Salto Tellez M, Goh B, Lee C, et al. Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma. J Hepatol. 2008;49:52-60 pubmed 出版商
  • 免疫组化; 人类
Huynh H, Chow K, Soo K, Toh H, Choo S, Foo K, et al. RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma. J Cell Mol Med. 2009;13:1371-80 pubmed 出版商
  • 免疫组化; 人类
Kagiwada H, Yashiki T, Ohshima A, Tadokoro M, Nagaya N, Ohgushi H. Human mesenchymal stem cells as a stable source of VEGF-producing cells. J Tissue Eng Regen Med. 2008;2:184-9 pubmed 出版商
  • 免疫组化; 人类
O Brien P, Davies M, Scurry J, Smith A, Barton C, Henderson M, et al. The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro. Br J Cancer. 2008;98:1085-93 pubmed 出版商
  • 免疫组化; 人类; 1:100
Yoshinaga K, Ito K, Moriya T, Nagase S, Takano T, Niikura H, et al. Expression of vasohibin as a novel endothelium-derived angiogenesis inhibitor in endometrial cancer. Cancer Sci. 2008;99:914-9 pubmed 出版商
  • 免疫组化; 人类
Fok T, Jan A, Peel S, Evans A, Clokie C, Sandor G. Hyperbaric oxygen results in increased vascular endothelial growth factor (VEGF) protein expression in rabbit calvarial critical-sized defects. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105:417-22 pubmed 出版商
  • 免疫组化; domestic rabbit; 1:200
Constantinides C, Tyritzis S, Evangelou C, Kyroudi A, Liatsikos E, Karamessinis P, et al. Vascular endothelial growth factor protein expression in a renal ablation rabbit model under prolonged warm and cold ischemia. Am J Nephrol. 2008;28:438-45 pubmed
  • 免疫组化; 人类
Lieto E, Ferraraccio F, Orditura M, Castellano P, Mura A, Pinto M, et al. Expression of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) is an independent prognostic indicator of worse outcome in gastric cancer patients. Ann Surg Oncol. 2008;15:69-79 pubmed
  • 免疫印迹; 人类
Hong S, Chang S, Yeom D, Kang J, Hong K. Differential regulation of thrombospondin-1 expression and antiangiogenesis of ECV304 cells by trichostatin A and helixor A. Anticancer Drugs. 2007;18:1005-14 pubmed
  • 免疫组化; 人类; 1:100
Skarlos D, Bai M, Goussia A, Samantas E, Galani E, Tsavdaridis D, et al. Expression of a molecular marker panel as a prognostic tool in gastric cancer patients treated postoperatively with docetaxel and irinotecan. A study of the Hellenic Cooperative Oncology Group. Anticancer Res. 2007;27:2973-83 pubmed
  • 酶联免疫吸附测定; 人类
Lee D, Kuo H, Chen C, Hsu J, Chou C, Wei Y, et al. IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway. Cell. 2007;130:440-55 pubmed
  • 免疫组化; 人类; 1:200
Tao X, Huang Y, Li R, Qing R, Ma L, Rhodus N, et al. Assessment of local angiogenesis and vascular endothelial growth factor in the patients with atrophic-erosive and reticular oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103:661-9 pubmed
  • 免疫组化; 人类; 1:10
Kaygusuz G, Tulunay O, Baltaci S, Gogus O. Microvessel density and regulators of angiogenesis in malignant and nonmalignant prostate tissue. Int Urol Nephrol. 2007;39:841-50 pubmed
  • 免疫组化; 人类
  • 免疫印迹; 人类
Ong C, Khoo Y, Tan E, Mukhopadhyay A, Do D, Han H, et al. Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion. J Pathol. 2007;211:95-108 pubmed
  • 免疫组化; 人类; 1:100
Yasuda H, Nakayama K, Watanabe M, Suzuki S, Fuji H, Okinaga S, et al. Nitroglycerin treatment may enhance chemosensitivity to docetaxel and carboplatin in patients with lung adenocarcinoma. Clin Cancer Res. 2006;12:6748-57 pubmed
  • 免疫组化; 人类; 1:50
Ioachim E, Michael M, Salmas M, Michael M, Stavropoulos N, Malamou Mitsi V. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha expression in bladder cancer and their associations with other angiogenesis-related proteins. Urol Int. 2006;77:255-63 pubmed
  • 免疫组化; 人类; 1:100
Yang L, Lu W, Huang G, Wang W. Correlation between CD105 expression and postoperative recurrence and metastasis of hepatocellular carcinoma. BMC Cancer. 2006;6:110 pubmed
  • 免疫组化; 人类; 1:50
Karavasilis V, Malamou Mitsi V, Briasoulis E, Tsanou E, Kitsou E, Pavlidis N. Clinicopathologic study of vascular endothelial growth factor, thrombospondin-1, and microvessel density assessed by CD34 in patients with stage III ovarian carcinoma. Int J Gynecol Cancer. 2006;16 Suppl 1:241-6 pubmed
  • 免疫组化; 人类; 1:100
Kim S, Cho N, Kim K, Lee J, Koo B, Kim J, et al. Correlations of oral tongue cancer invasion with matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) expression. J Surg Oncol. 2006;93:330-7 pubmed
  • 免疫组化; 大鼠; 1:100
Shirai M, Yamanaka M, Shiina H, Igawa M, Kawakami T, Ishii N, et al. Vascular endothelial growth factor restores erectile function through modulation of the insulin-like growth factor system and sex hormone receptors in diabetic rat. Biochem Biophys Res Commun. 2006;341:755-62 pubmed
  • 免疫组化; 小鼠
Lin Y, Lai M, Lei H, Wing L. Neutrophils and macrophages promote angiogenesis in the early stage of endometriosis in a mouse model. Endocrinology. 2006;147:1278-86 pubmed
  • 免疫组化; 人类; 1:50
Pakos E, Goussia A, Tsekeris P, Papachristou D, Stefanou D, Agnantis N. Expression of vascular endothelial growth factor and its receptor, KDR/Flk-1, in soft tissue sarcomas. Anticancer Res. 2005;25:3591-6 pubmed
  • 免疫印迹; 大鼠; 1:100
Arbos M, Ferrando J, Quiles M, Vidal J, Lopez Cano M, Gil J, et al. Improved surgical mesh integration into the rat abdominal wall with arginine administration. Biomaterials. 2006;27:758-68 pubmed
  • 免疫组化; 人类; 1:50
Rosen D, Wang L, Atkinson J, Yu Y, Lu K, Diamandis E, et al. Potential markers that complement expression of CA125 in epithelial ovarian cancer. Gynecol Oncol. 2005;99:267-77 pubmed
  • 免疫组化; 人类
Saylam G, Yücel O, Sungur A, Onerci M. Proliferation, angiogenesis and hormonal markers in juvenile nasopharyngeal angiofibroma. Int J Pediatr Otorhinolaryngol. 2006;70:227-34 pubmed
  • 免疫组化; 牛
Isobe N, Kitabayashi M, Yoshimura Y. Microvascular distribution and vascular endothelial growth factor expression in bovine cystic follicles. Domest Anim Endocrinol. 2005;29:634-45 pubmed
  • 免疫组化; 人类
Invernizzi R, Travaglino E, De Amici M, Brugnatelli S, Ramajoli I, Rovati B, et al. Thalidomide treatment reduces apoptosis levels in bone marrow cells from patients with myelodysplastic syndromes. Leuk Res. 2005;29:641-7 pubmed
  • 免疫组化; 人类
Huang G, Yang L, Lu W. Expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in hepatocellular carcinoma: Impact on neovascularization and survival. World J Gastroenterol. 2005;11:1705-8 pubmed
  • 免疫组化; 人类; 1:50
Karavasilis V, Malamou Mitsi V, Briasoulis E, Tsanou E, Kitsou E, Kalofonos H, et al. Angiogenesis in cancer of unknown primary: clinicopathological study of CD34, VEGF and TSP-1. BMC Cancer. 2005;5:25 pubmed
  • 免疫组化; 人类; 1:50
Kyzas P, Stefanou D, Batistatou A, Agnantis N. Potential autocrine function of vascular endothelial growth factor in head and neck cancer via vascular endothelial growth factor receptor-2. Mod Pathol. 2005;18:485-94 pubmed
Cuzziol C, Marzochi L, Possebon V, Kawasaki Oyama R, Mattos M, Junior V, et al. Regulation of VEGFA, KRAS, and NFE2L2 Oncogenes by MicroRNAs in Head and Neck Cancer. Int J Mol Sci. 2022;23: pubmed 出版商
Yan M, Li J, Yan L, Li X, Chen J. Transcription factor Foxp1 is essential for the induction of choroidal neovascularization. Eye Vis (Lond). 2022;9:10 pubmed 出版商
Li W, Mao M, Hu N, Wang J, Huang J, Gu S. In vitro evaluation of periapical lesion-derived stem cells for dental pulp tissue engineering. FEBS Open Bio. 2022;12:270-284 pubmed 出版商
Haneda S, Dini P, Esteller Vico A, Scoggin K, Squires E, Troedsson M, et al. Estrogens Regulate Placental Angiogenesis in Horses. Int J Mol Sci. 2021;22: pubmed 出版商
Su C, Jao T, Urban Z, Huang Y, See D, Tsai Y, et al. LTBP4 affects renal fibrosis by influencing angiogenesis and altering mitochondrial structure. Cell Death Dis. 2021;12:943 pubmed 出版商
Zhang L, Li X, Shi C, Ran G, Peng Y, Zeng S, et al. Biocompatibility and Angiogenic Effect of Chitosan/Graphene Oxide Hydrogel Scaffolds on EPCs. Stem Cells Int. 2021;2021:5594370 pubmed 出版商
Wang X, Fang Y, Zhou Y, Guo X, Xu K, Li C, et al. SDF-1α/MicroRNA-134 Axis Regulates Nonfunctioning Pituitary Neuroendocrine Tumor Growth via Targeting VEGFA. Front Endocrinol (Lausanne). 2020;11:566761 pubmed 出版商
Liu B, Gao W, Sun W, Li L, Wang C, Yang X, et al. Promoting roles of long non-coding RNA FAM83H-AS1 in bladder cancer growth, metastasis, and angiogenesis through the c-Myc-mediated ULK3 upregulation. Cell Cycle. 2020;19:3546-3562 pubmed 出版商
Hazzaa H, El Shiekh M, Abdelgawad N, Gouda O, Kamal N. Correlation of VEGF and MMP-2 levels in oral lichen planus: An in vivo immunohistochemical study. J Oral Biol Craniofac Res. 2020;10:747-752 pubmed 出版商
Lei X, Cheng L, Lin H, Pang M, Yao Z, Chen C, et al. Human Salivary Histatin-1 Is More Efficacious in Promoting Acute Skin Wound Healing Than Acellular Dermal Matrix Paste. Front Bioeng Biotechnol. 2020;8:999 pubmed 出版商
Ullah M, Liu D, Rai S, Razavi M, Concepcion W, Thakor A. Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury. Stem Cell Res Ther. 2020;11:398 pubmed 出版商
Yu M, Pan H, Che N, Li L, Wang C, Wang Y, et al. Microwave ablation of primary breast cancer inhibits metastatic progression in model mice via activation of natural killer cells. Cell Mol Immunol. 2020;: pubmed 出版商
Hou Z, Xu X, Fu X, Zhou L, Liu S, Tan D. Long non-coding RNA MALAT1 promotes angiogenesis and immunosuppressive properties of HCC cells by sponging miR-140. Am J Physiol Cell Physiol. 2020;318:C649-C663 pubmed 出版商
Shi J, Zhang D, Zhong Z, Zhang W. lncRNA ROR promotes the progression of renal cell carcinoma through the miR‑206/VEGF axis. Mol Med Rep. 2019;20:3782-3792 pubmed 出版商
Jeon H, Kim J, Choi J, Han E, Song C, Lee J, et al. Effects of the Extracts from Fruit and Stem of Camellia japonica on Induced Pluripotency and Wound Healing. J Clin Med. 2018;7: pubmed 出版商
Khandelwal S, Boylan M, Spallholz J, Gollahon L. Cytotoxicity of Selenium Immunoconjugates against Triple Negative Breast Cancer Cells. Int J Mol Sci. 2018;19: pubmed 出版商
Martano M, Power K, Restucci B, Pagano I, Altamura G, Borzacchiello G, et al. Expression of vascular endothelial growth factor (VEGF) in equine sarcoid. BMC Vet Res. 2018;14:266 pubmed 出版商
Raposo T, Pires I, Carvalho M, Prada J, Argyle D, Queiroga F. Tumour-associated macrophages are associated with vascular endothelial growth factor expression in canine mammary tumours. Vet Comp Oncol. 2015;13:464-74 pubmed 出版商
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图像
图像 1 :
赛默飞世尔 MA5-13182 图像 1
Formalin-fixed, paraffin-embedded human angiosarcoma stained with VEGF antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.
产品信息
产品类型 :
抗体
产品名称 :
血管内皮生长因子单克隆抗体(JH121)
目录# :
MA5-13182
规格 :
500微升
价格 :
美国419
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠, 兔
应用 :
Immunocytochemistry: 1:20-1:100, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1-2 µg/mL
物种 :
人类, 小鼠, 兔
克隆 :
JH121
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
VEGF (vascular endothelial growth factor) which is a 45 kDa homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. VEGF has a variety of effects on vascular endothelium, including the ability to promote endothelial cell viability, mitogenesis, chemotaxis, and vascular permeability. The VEGF family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis, and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. Studies have shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis. Elevated levels of VEGF is linked to POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, Skin changes) also known as Crow-Fukase syndrome which affects multiple organs in the body.
免疫原 :
重组人类VEGF121
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:20-1:100, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1-2 µg/mL
别名 :
angiogenic factor; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor; vascular endothelial growth factor (VEGF) precursor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; vascular endothelial growth factor 189; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; vascular permeability factor; Vasculotropin; VEGF; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; VEGFA165b; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06
更多信息或购买 :
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公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国