产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD45 Antibody Cocktail
目录 :
MA5-13197
规格 :
500微升
价格 :
美国340
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
PD7/26/16, 2B11
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 13
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 1:500; 图 2e
Lim K, Dayem A, Choi Y, Lee Y, An J, Gil M, et al. High Therapeutic and Esthetic Properties of Extracellular Vesicles Produced from the Stem Cells and Their Spheroids Cultured from Ocular Surgery-Derived Waste Orbicularis Oculi Muscle Tissues. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1a
Szalayova G, Ogrodnik A, Spencer B, Wade J, Bunn J, Ambaye A, et al. Human breast cancer biopsies induce eosinophil recruitment and enhance adjacent cancer cell proliferation. Breast Cancer Res Treat. 2016;157:461-74 pubmed 出版商
  • 免疫组化; 小鼠
Singh M, Singh P, Gaudray G, Musumeci L, Thielen C, Vaira D, et al. An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2R?null mice allows HIV replication and development of anti-HIV immune responses. PLoS ONE. 2012;7:e38491 pubmed 出版商
  • 免疫组化; 人类; 1:100
Yu G, Kong L, Qu G, Zhang Q, Wang W, Jiang L. Composite lymphoma in the anterior mediastinum: a case report and review of the literature. Diagn Pathol. 2011;6:60 pubmed 出版商
  • 流式细胞仪; 人类
Proia T, Keller P, Gupta P, Klebba I, Jones A, Sedic M, et al. Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. Cell Stem Cell. 2011;8:149-63 pubmed 出版商
  • 流式细胞仪; 人类; 1:50
Zhao J, Gao Z, Mei H, Li Y, Wang Y. Differentiation of human mesenchymal stem cells: the potential mechanism for estrogen-induced preferential osteoblast versus adipocyte differentiation. Am J Med Sci. 2011;341:460-8 pubmed 出版商
  • 免疫组化; 人类
Balci S, Engiz O, Okten G, Sipahier M, Gursu G, Kandemir B. A 19-year follow-up of a patient with type 3 ectrodactyly-ectodermal dysplasia-clefting syndrome who developed non-Hodgkin lymphoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:e91-5 pubmed 出版商
  • 流式细胞仪; 人类
He X, Li Y, Wang X, Guo X, Niu Y. [Mesenchymal stem cells transduced by PLEGFP-N1 retroviral vector maintain their biological features and differentiation]. Chin Med J (Engl). 2005;118:1728-34 pubmed
  • 免疫组化; 人类
Gucer F, Altaner S, Mulayim N, Yapicier O. Invasive inflammatory pseudotumor of uterine cervix: a case report. Gynecol Oncol. 2005;98:325-8 pubmed
  • 免疫组化; 人类
Zhang Y, Yuan F, Jia G, Zhang J, Hu L, Huang L, et al. CIK cells from patients with HCC possess strong cytotoxicity to multidrug-resistant cell line Bel-7402/R. World J Gastroenterol. 2005;11:3339-45 pubmed
Beccard I, Hofmann L, Schroeder J, Ludwig S, Laban S, Brunner C, et al. Immune Suppressive Effects of Plasma-Derived Exosome Populations in Head and Neck Cancer. Cancers (Basel). 2020;12: pubmed 出版商
Pinto A, Ilinykh A, Ivey M, Kuwabara J, D Antoni M, Debuque R, et al. Revisiting Cardiac Cellular Composition. Circ Res. 2016;118:400-9 pubmed 出版商
Kersemaekers A, Van Weeren P, Oosterhuis J, Looijenga L. Involvement of the Fas/FasL pathway in the pathogenesis of germ cell tumours of the adult testis. J Pathol. 2002;196:423-9 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD45 Antibody Cocktail
目录# :
MA5-13197
规格 :
500微升
价格 :
美国340
克隆性 :
Cocktail
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:10-1:100
物种 :
人类
克隆 :
PD7/26/16, 2B11
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling. CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.
免疫原 :
PD7/26/16: human peripheral blood lymphocytes maintained in T cell growth factor. 2B11: isolated neoplastic cells from T cell lymphoma.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:10-1:100
别名 :
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国