产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
凝血酶敏感素1单克隆抗体(A4.1)
目录 :
MA5-13377
规格 :
500微升
价格 :
美国496
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
A4.1
反应物种 :
人类, 小鼠, 大鼠, 鸡, 牛, pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 37
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| Johansson A, Olerud J, Johansson M, Carlsson P. Angiostatic factors normally restrict islet endothelial cell proliferation and migration: implications for islet transplantation. Transpl Int. 2009;22:1182-8 pubmed
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| Park J, Lee H, Ko K, Park S, Kim J, Choe G, et al. Meteorin regulates angiogenesis at the gliovascular interface. Glia. 2008;56:247-58 pubmed
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| Kaipainen A, Kieran M, Huang S, Butterfield C, Bielenberg D, Mostoslavsky G, et al. PPARalpha deficiency in inflammatory cells suppresses tumor growth. PLoS ONE. 2007;2:e260 pubmed
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| Guzik K, Bzowska M, Smagur J, Krupa O, Sieprawska M, Travis J, et al. A new insight into phagocytosis of apoptotic cells: proteolytic enzymes divert the recognition and clearance of polymorphonuclear leukocytes by macrophages. Cell Death Differ. 2007;14:171-82 pubmed
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| Naumov G, Bender E, Zurakowski D, Kang S, Sampson D, Flynn E, et al. A model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotype. J Natl Cancer Inst. 2006;98:316-25 pubmed
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| Kang J, Kim S, Hong K. Induction of TSP1 gene expression by heat shock is mediated via an increase in mRNA stability. FEBS Lett. 2006;580:510-6 pubmed
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| Kermorvant Duchemin E, Sennlaub F, Sirinyan M, Brault S, Andelfinger G, Kooli A, et al. Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration. Nat Med. 2005;11:1339-45 pubmed
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| Hasina R, Pontier A, Fekete M, Martin L, Qi X, Brigaudeau C, et al. NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype. Oncogene. 2006;25:588-98 pubmed
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| Gomez Duran A, Mulero Navarro S, Chang X, Fernandez Salguero P. LTBP-1 blockade in dioxin receptor-null mouse embryo fibroblasts decreases TGF-beta activity: Role of extracellular proteases plasmin and elastase. J Cell Biochem. 2006;97:380-92 pubmed
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| Cambier S, Gline S, Mu D, Collins R, Araya J, Dolganov G, et al. Integrin alpha(v)beta8-mediated activation of transforming growth factor-beta by perivascular astrocytes: an angiogenic control switch. Am J Pathol. 2005;166:1883-94 pubmed
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Emonard H, Bellon G, Troeberg L, Berton A, Robinet A, Henriet P, et al. Low density lipoprotein receptor-related protein mediates endocytic clearance of pro-MMP-2.TIMP-2 complex through a thrombospondin-independent mechanism. J Biol Chem. 2004;279:54944-51 pubmed
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Doyen V, Rubio M, Braun D, Nakajima T, Abe J, Saito H, et al. Thrombospondin 1 is an autocrine negative regulator of human dendritic cell activation. J Exp Med. 2003;198:1277-83 pubmed
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Bocci G, Francia G, Man S, Lawler J, Kerbel R. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc Natl Acad Sci U S A. 2003;100:12917-22 pubmed
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Rofstad E, Henriksen K, Galappathi K, Mathiesen B. Antiangiogenic treatment with thrombospondin-1 enhances primary tumor radiation response and prevents growth of dormant pulmonary micrometastases after curative radiation therapy in human melanoma xenografts. Cancer Res. 2003;63:4055-61 pubmed
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Lopes N, Gregg D, Vasudevan S, Hassanain H, Goldschmidt Clermont P, Kovacic H. Thrombospondin 2 regulates cell proliferation induced by Rac1 redox-dependent signaling. Mol Cell Biol. 2003;23:5401-8 pubmed
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Rhodes K, Moon L, Fawcett J. Inhibiting cell proliferation during formation of the glial scar: effects on axon regeneration in the CNS. Neuroscience. 2003;120:41-56 pubmed
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Sakai K, Sumi Y, Muramatsu H, Hata K, Muramatsu T, Ueda M. Thrombospondin-1 promotes fibroblast-mediated collagen gel contraction caused by activation of latent transforming growth factor beta-1. J Dermatol Sci. 2003;31:99-109 pubmed
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Siegel Axel D, Runge H, Seipel L, Riessen R. Effects of cerivastatin on human arterial smooth muscle cell growth and extracellular matrix expression at varying glucose and low-density lipoprotein levels. J Cardiovasc Pharmacol. 2003;41:422-33 pubmed
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Volpert O, Pili R, Sikder H, Nelius T, Zaichuk T, Morris C, et al. Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1. Cancer Cell. 2002;2:473-83 pubmed
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Goel M, Diamond S. Adhesion of normal erythrocytes at depressed venous shear rates to activated neutrophils, activated platelets, and fibrin polymerized from plasma. Blood. 2002;100:3797-803 pubmed
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Rofstad E, Graff B. Thrombospondin-1-mediated metastasis suppression by the primary tumor in human melanoma xenografts. J Invest Dermatol. 2001;117:1042-9 pubmed
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Tenan M, Fulci G, Albertoni M, Diserens A, Hamou M, El Atifi Borel M, et al. Thrombospondin-1 is downregulated by anoxia and suppresses tumorigenicity of human glioblastoma cells. J Exp Med. 2000;191:1789-98 pubmed
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Shi S, Cote R, Hawes D, Thu S, Shi Y, Young L, et al. Calcium-induced modification of protein conformation demonstrated by immunohistochemistry: What is the signal?. J Histochem Cytochem. 1999;47:463-70 pubmed
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Gupta K, Gupta P, Solovey A, Hebbel R. Mechanism of interaction of thrombospondin with human endothelium and inhibition of sickle erythrocyte adhesion to human endothelial cells by heparin. Biochim Biophys Acta. 1999;1453:63-73 pubmed
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图像
图像 1 :
产品信息
产品类型 :
抗体
产品名称 :
凝血酶敏感素1单克隆抗体(A4.1)
目录# :
MA5-13377
规格 :
500微升
价格 :
美国496
克隆性 :
单克隆
纯度 :
硫酸铵沉淀
宿主 :
小鼠
反应物种 :
牛, 鸡, 人类, 小鼠, 大鼠
应用 :
Flow Cytometry: Assay Dependent, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: 1-2 µg/mL
物种 :
牛, 鸡, 人类, 小鼠, 大鼠
克隆 :
A4.1
抗体亚型 :
IgM
储存 :
4° C
描述 :
Thrombospondin is a protein from platelet a-granules. It is made up of three identical subunits bound by interchain disulfides. It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.
免疫原 :
Calcium-replete, native purified human TSP from the supernatant of thrombin-activated platelets
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay Dependent, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: 1-2 µg/mL
别名 :
糖蛋白G;tbsp1;THBS;凝血酶敏感素1;THBS-1;血小板反应蛋白;凝血酶敏感素1;凝血酶敏感素1;血小板反应蛋白1p180;血小板反应蛋白p50;ThrombospondinTHBS1;TSP;TSP1;TSP-1
更多信息或购买 :
公司信息
赛默飞世尔