基质金属蛋白酶9单克隆抗体(GE-213) | 赛默飞世尔 MA5-13595 产品信息

产品简要

公司名称 :

赛默飞世尔

其他品牌 :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

产品类型 :

抗体

产品名称 :

基质金属蛋白酶9单克隆抗体(GE-213)

MA5-13595

规格 :

500微升

价格 :

美国450.00

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

GE-213

反应物种 :

人类

应用 :

免疫组化, 免疫沉淀, 免疫组化-冰冻切片

更多信息或购买 :

赛默飞世尔产品网页

文章摘录数: 50

参考文献
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Tao Y, Chai D, Ma L, Zhang T, Feng Z, Cheng Z, et al. Identification of distinct gene expression profiles between esophageal squamous cell carcinoma and adjacent normal epithelial tissues. Tohoku J Exp Med. 2012;226:301-11 pubmed
Cheng C, Hsieh H, Hsiao L, Yang C. PI3-K/Akt/JNK/NF-?B is essential for MMP-9 expression and outgrowth in human limbal epithelial cells on intact amniotic membrane. Stem Cell Res. 2012;9:9-23 pubmed 出版商
Lee W, Chung C, Hsiao C, Chou Y, Hsueh P, Yang P, et al. Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-?B activation. Phytomedicine. 2012;19:270-7 pubmed 出版商
Lin C, Jin J, Yu C, Tsai W. Expression of LGR8 and related biomarkers in hepatocellular carcinoma: correlation with clinicopathological parameters. Chin J Physiol. 2011;54:161-8 pubmed
Bidgoli S, Karimi M, Asami Z, Baher H, Djamali Zavarhei M. Association between testicular Aryl hydrocarbon Receptor levels and idiopathic male infertility: a case-control study in Iran. Sci Total Environ. 2011;409:3267-73 pubmed 出版商
Alshenawy H. Immunohistochemical expression of epidermal growth factor receptor, E-cadherin, and matrix metalloproteinase-9 in ovarian epithelial cancer and relation to patient deaths. Ann Diagn Pathol. 2010;14:387-95 pubmed 出版商
Gonzalez L, Junquera S, del Casar J, Gonzalez L, Marín L, Gonzalez Reyes S, et al. Immunohistochemical study of matrix metalloproteinases and their inhibitors in pure and mixed invasive and in situ ductal carcinomas of the breast. Hum Pathol. 2010;41:980-9 pubmed 出版商
Escaff S, Fernandez J, Gonzalez L, Suarez A, Gonzalez Reyes S, Gonzalez J, et al. Study of matrix metalloproteinases and their inhibitors in prostate cancer. Br J Cancer. 2010;102:922-9 pubmed 出版商
Gonzalez L, Gonzalez Reyes S, Junquera S, Marin L, Gonzalez L, del Casar J, et al. Expression of metalloproteases and their inhibitors by tumor and stromal cells in ductal carcinoma in situ of the breast and their relationship with microinvasive events. J Cancer Res Clin Oncol. 2010;136:1313-21 pubmed 出版商
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Lee W, Kim S, Ryu W. Progression and observational frequency of atheromatous plaques in autopsied coronary arteries. Korean Circ J. 2009;39:399-407 pubmed 出版商
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产品信息

产品类型 :

抗体

产品名称 :

基质金属蛋白酶9单克隆抗体(GE-213)

目录# :

MA5-13595

规格 :

500微升

价格 :

美国450.00

克隆性 :

单克隆

纯度 :

蛋白质G

宿主 :

小鼠

反应物种 :

人类

应用 :

Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: 2 µg/mL, Inhibition Assays: 2-4 µg/mL

物种 :

人类

克隆 :

GE-213

抗体亚型 :

IgG1

储存 :

4° C

描述 :

MMP9 (matrix metallopeptidase 9, GELB, CLG4B) is a matrix metalloproteinase, a family of zinc and calcium-dependent endopeptidases that degrade extracellular matrix proteins. MMP9 is secreted as a 92kDa zymogen and cleavage of pro-MMP9 results in the active enzyme with a molecular weight of 82kDa. MMP9 has a gelatin-binding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen-homologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodeling, wound healing, tumor growth and metastasis. MMP9 is supplied by bone marrow-derived cells and contributes to skin carcinogenesis. Further, MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. Studies have shown that elevated MMP9 is associated with progression of idiopathic atrial fibrillation and aortic aneurysm.

免疫原 :

纯化人类基质金属蛋白酶-9

格式 :

液体

应用w/稀释 :

Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: 2 µg/mL, Inhibition Assays: 2-4 µg/mL

别名 :

67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; 92kD gelatinase; 92kD type IV collagenase; 92kDa gelatinase; 92kDa type IV collagenase; 92-kDa type IV collagenase; AW743869; B/MMP9; Clg4b; collagenase type IVB; fj05a08; Gel B; gelatinase B; Gelatinase-B; GELB; macrophage gelatinase; MANDP2; matrix metallo protease; matrix metallopeptidase 9; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9; matrix metalloproteinase 9 (gelatinase B 92-kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92kDa matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92-kDa type IV collagenase); Matrix metalloproteinase9; matrix metalloproteinase-9; MMP; Mmp9; MMP-9; mmp9 protein; MMP-9 protein; MMPs; Preproform of 92-kDa type IV collagenase (MMP-9): N-terminal; pro-MMP-9; type IV collagenase; type V collagenase; wu:fb02g06; wu:fb07b05; wu:fi98c09; wu:fj05a08; ZFMMP-9; zgc:64165

更多信息或购买 :

赛默飞世尔产品网页

公司信息

赛默飞世尔

上海浦东新金桥路27号7号楼

analyze.cn@thermofisher.com

http://www.thermo.com.cn

1084193588

公司总部: 美国