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抗体

Rb Monoclonal Antibody (XZ133)

MA5-13653

500微升

美国420.00

单克隆

小鼠

未共轭

XZ133

人类, 小鼠, 鸡

免疫细胞化学, 免疫沉淀

Rb Monoclonal Antibody (XZ133)

MA5-13653

500微升

美国420.00

单克隆

蛋白质G

小鼠

鸡, 人类, 小鼠

Immunocytochemistry: Assay-dependent, Immunoprecipitation: 2 µg/mL

鸡, 人类, 小鼠

XZ133

IgG1

4° C

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Recombinant human Rb protein corresponding to amino acids 387-928

液体

Immunocytochemistry: Assay-dependent, Immunoprecipitation: 2 µg/mL

Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein