产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
细胞角蛋白10单克隆抗体(DE-K10)
目录 :
MA5-13705
规格 :
500微升
价格 :
美国395.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DE-K10
反应物种 :
人类, 小鼠, 大鼠, , , 国内马
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 45
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:100; 图 4e
Ashcroft F, Mahammad N, Midtun Flatekvål H, Jullumstrø Feuerherm A, Johansen B. cPLA2α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation. Biomolecules. 2020;10: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 5
Stewart M, Bechberger J, Welch I, Naus C, Laird D. Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer. Oncotarget. 2015;6:37185-99 pubmed 出版商
  • 免疫组化-石蜡切片; 国内马; 1:100; 图 1
  • 免疫印迹; 国内马; 1:1000; 图 2
Linardi R, Megee S, Mainardi S, Senoo M, Galantino Homer H. Expression and localization of epithelial stem cell and differentiation markers in equine skin, eye and hoof. Vet Dermatol. 2015;26:213-e47 pubmed 出版商
  • 免疫组化; 人类; 1:100
Matsusaki M, Fujimoto K, Shirakata Y, Hirakawa S, Hashimoto K, Akashi M. Development of full-thickness human skin equivalents with blood and lymph-like capillary networks by cell coating technology. J Biomed Mater Res A. 2015;103:3386-96 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2b
von Neubeck C, Geniza M, Kauer P, Robinson R, Chrisler W, Sowa M. The effect of low dose ionizing radiation on homeostasis and functional integrity in an organotypic human skin model. Mutat Res. 2015;775:10-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
van Drongelen V, Danso M, Out J, Mulder A, Lavrijsen A, Bouwstra J, et al. Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro. Cell Tissue Res. 2015;361:789-97 pubmed 出版商
  • 免疫印迹; 人类; 1:200
Neumann C, Bigliardi Qi M, Widmann C, Bigliardi P. The δ-opioid receptor affects epidermal homeostasis via ERK-dependent inhibition of transcription factor POU2F3. J Invest Dermatol. 2015;135:471-480 pubmed 出版商
  • 免疫组化; 人类; 图 1
Ouyang H, Xue Y, Lin Y, Zhang X, Xi L, Patel S, et al. WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis. Nature. 2014;511:358-61 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:600; 表 3
Lindström A, Hellberg D. Immunohistochemical LRIG3 expression in cervical intraepithelial neoplasia and invasive squamous cell cervical cancer: association with expression of tumor markers, hormones, high-risk HPV-infection, smoking and patient outcome. Eur J Histochem. 2014;58:2227 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 6
Sauder C, Koziel J, Choi M, Fox M, Grimes B, Badve S, et al. Phenotypic plasticity in normal breast derived epithelial cells. BMC Cell Biol. 2014;15:20 pubmed 出版商
  • 免疫组化; 人类; 1:100
van Drongelen V, Danso M, Mulder A, Mieremet A, Van Smeden J, Bouwstra J, et al. Barrier properties of an N/TERT-based human skin equivalent. Tissue Eng Part A. 2014;20:3041-9 pubmed 出版商
  • 免疫组化; 人类; 200 mg/ml
Mitchell D, Israr M, Alam S, Dinello D, Kishel J, Jia R, et al. HIV nucleoside reverse transcriptase inhibitors efavirenz and tenofovir change the growth and differentiation of primary gingival epithelium. HIV Med. 2014;15:196-202 pubmed 出版商
  • 免疫组化; 大鼠
Haisma E, Rietveld M, de Breij A, van Dissel J, El Ghalbzouri A, Nibbering P. Inflammatory and antimicrobial responses to methicillin-resistant Staphylococcus aureus in an in vitro wound infection model. PLoS ONE. 2013;8:e82800 pubmed 出版商
  • 免疫组化; 人类; 2 ug/ml
von Neubeck C, Shankaran H, Geniza M, Kauer P, Robinson R, Chrisler W, et al. Integrated experimental and computational approach to understand the effects of heavy ion radiation on skin homeostasis. Integr Biol (Camb). 2013;5:1229-43 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 6
Lian X, Selekman J, Bao X, Hsiao C, Zhu K, Palecek S. A small molecule inhibitor of SRC family kinases promotes simple epithelial differentiation of human pluripotent stem cells. PLoS ONE. 2013;8:e60016 pubmed 出版商
  • 免疫组化; 人类
Pal S, Sakamoto K, Aragaki T, Akashi T, Yamaguchi A. The expression profiles of acidic epithelial keratins in ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115:523-31 pubmed 出版商
  • 免疫细胞化学; 人类
Moffatt Jauregui C, Robinson B, de Moya A, Brockman R, Roman A, Cash M, et al. Establishment and characterization of a telomerase immortalized human gingival epithelial cell line. J Periodontal Res. 2013;48:713-21 pubmed 出版商
  • 免疫组化; 人类; 1:200
Kretz M, Siprashvili Z, Chu C, Webster D, Zehnder A, Qu K, et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature. 2013;493:231-5 pubmed 出版商
  • 免疫组化; 人类; 1:50
Commandeur S, van Drongelen V, de Gruijl F, El Ghalbzouri A. Epidermal growth factor receptor activation and inhibition in 3D in vitro models of normal skin and human cutaneous squamous cell carcinoma. Cancer Sci. 2012;103:2120-6 pubmed 出版商
  • 免疫印迹; 人类
Yang F, Waters K, Webb Robertson B, Sowa M, von Neubeck C, Aldrich J, et al. Quantitative phosphoproteomics identifies filaggrin and other targets of ionizing radiation in a human skin model. Exp Dermatol. 2012;21:352-7 pubmed 出版商
  • 免疫组化; 人类; 1:500
Lara M, Gonzalez Gonzalez E, Speaker T, Hickerson R, Leake D, Milstone L, et al. Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays. Hum Gene Ther. 2012;23:816-23 pubmed 出版商
  • 免疫组化; 人类; 200 mg/mL
Mitchell D, Israr M, Alam S, Kishel J, Dinello D, Meyers C. Effect of the HIV nucleoside reverse transcriptase inhibitor zidovudine on the growth and differentiation of primary gingival epithelium. HIV Med. 2012;13:276-90 pubmed 出版商
  • 免疫细胞化学; 人类
Alexaki V, Pelekanou V, Notas G, Venihaki M, Kampa M, Dessirier V, et al. B-cell maturation antigen (BCMA) activation exerts specific proinflammatory effects in normal human keratinocytes and is preferentially expressed in inflammatory skin pathologies. Endocrinology. 2012;153:739-49 pubmed 出版商
  • 免疫组化; 人类
Li B, Li J, Devlin B, Markert M. Thymic microenvironment reconstitution after postnatal human thymus transplantation. Clin Immunol. 2011;140:244-59 pubmed 出版商
  • 免疫组化; 人类
Sakamoto K, Aragaki T, Morita K, Kawachi H, Kayamori K, Nakanishi S, et al. Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia: a clue for histopathogenesis. Histopathology. 2011;58:531-42 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Obarzanek Fojt M, Favre B, Kypriotou M, Ryser S, Huber M, Hohl D. Homeodomain-only protein HOP is a novel modulator of late differentiation in keratinocytes. Eur J Cell Biol. 2011;90:279-90 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Obarzanek Fojt M, Favre B, Huber M, Ryser S, Moodycliffe A, Wipff P, et al. Induction of p38, tumour necrosis factor-? and RANTES by mechanical stretching of keratinocytes expressing mutant keratin 10R156H. Br J Dermatol. 2011;164:125-34 pubmed 出版商
  • 免疫组化; 人类
Israr M, Mitchell D, Alam S, Dinello D, Kishel J, Meyers C. The HIV protease inhibitor lopinavir/ritonavir (Kaletra) alters the growth, differentiation and proliferation of primary gingival epithelium. HIV Med. 2011;12:145-56 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫组化; 人类; 1:350
Sen G, Reuter J, Webster D, Zhu L, Khavari P. DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature. 2010;463:563-7 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:600; 表 1
Samir R, Asplund A, Tot T, Pekar G, Hellberg D. Tissue tumor marker expression in smokers, including serum cotinine concentrations, in women with cervical intraepithelial neoplasia or normal squamous cervical epithelium. Am J Obstet Gynecol. 2010;202:579.e1-7 pubmed 出版商
  • 免疫组化; 人类
Metallo C, Azarin S, Moses L, Ji L, de Pablo J, Palecek S. Human embryonic stem cell-derived keratinocytes exhibit an epidermal transcription program and undergo epithelial morphogenesis in engineered tissue constructs. Tissue Eng Part A. 2010;16:213-23 pubmed 出版商
  • 免疫组化; 人类; 1:100
Charest J, Jennings J, King W, Kowalczyk A, Garcia A. Cadherin-mediated cell-cell contact regulates keratinocyte differentiation. J Invest Dermatol. 2009;129:564-72 pubmed 出版商
  • 免疫组化; 人类
Markert M, Li J, Devlin B, Hoehner J, Rice H, Skinner M, et al. Use of allograft biopsies to assess thymopoiesis after thymus transplantation. J Immunol. 2008;180:6354-64 pubmed
  • 免疫组化; 人类; 1:50
Lalli A, Tilakaratne W, Ariyawardana A, Fitchett C, Leigh I, Hagi Pavli E, et al. An altered keratinocyte phenotype in oral submucous fibrosis: correlation of keratin K17 expression with disease severity. J Oral Pathol Med. 2008;37:211-20 pubmed 出版商
Hogervorst M, Rietveld M, de Gruijl F, El Ghalbzouri A. A shift from papillary to reticular fibroblasts enables tumour-stroma interaction and invasion. Br J Cancer. 2018;118:1089-1097 pubmed 出版商
Mehta F, Son J, Hewitt S, Jang E, Lydon J, Korach K, et al. Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus. Oncotarget. 2016;7:17455-67 pubmed 出版商
Mugita Y, Minematsu T, Huang L, Nakagami G, Kishi C, Ichikawa Y, et al. Histopathology of Incontinence-Associated Skin Lesions: Inner Tissue Damage Due to Invasion of Proteolytic Enzymes and Bacteria in Macerated Rat Skin. PLoS ONE. 2015;10:e0138117 pubmed 出版商
Hughes M, Jiang T, Lin S, Leung Y, Kobielak K, Widelitz R, et al. Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis. J Invest Dermatol. 2014;134:24-32 pubmed 出版商
Fukui D, Bando G, Ishikawa Y, Kadota K. Adenosquamous carcinoma with cilium formation, mucin production and keratinization in the nasal cavity of a red fox (Vulpes vulpes schrencki). J Comp Pathol. 2007;137:142-5 pubmed
Aho S. Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases. Exp Dermatol. 2004;13:700-7 pubmed
Chang Y, Liu H, Wang W, Lee D, Tsai S. A study of cytokeratin profiles in localized cutaneous amyloids. Arch Dermatol Res. 2004;296:83-8 pubmed
Apaydin R, Gurbuz Y, Bayramgurler D, Muezzinoglu B, Bilen N. Cytokeratin expression in lichen amyloidosus and macular amyloidosis. J Eur Acad Dermatol Venereol. 2004;18:305-9 pubmed
Hale L, Buckley R, Puck J, Patel D. Abnormal development of thymic dendritic and epithelial cells in human X-linked severe combined immunodeficiency. Clin Immunol. 2004;110:63-70 pubmed
Hale L, Markert M. Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus. J Immunol. 2004;172:617-24 pubmed
Sanchez Carbayo M, Socci N, Charytonowicz E, Lu M, Prystowsky M, Childs G, et al. Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes. Cancer Res. 2002;62:6973-80 pubmed
产品信息
产品类型 :
抗体
产品名称 :
细胞角蛋白10单克隆抗体(DE-K10)
目录# :
MA5-13705
规格 :
500微升
价格 :
美国395.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
狗, 猫, 人类, 大鼠
应用 :
Immunohistochemistry (Paraffin): 0.5-1.0 µg/mL, Western Blot: 2 µg/mL
物种 :
狗, 猫, 人类, 大鼠
克隆 :
DE-K10
抗体亚型 :
IgG1
储存 :
4° C
描述 :
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.
免疫原 :
Cytoskeletal preparation extracted from human ectocervical epithelium
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 0.5-1.0 µg/mL, Western Blot: 2 µg/mL
别名 :
56 kDa cytokeratin; BCIE; BIE; CK10; CK-10; CK-17; cytokeratin 10; cytokeratin-10; cytokeratin-17; D130054E02Rik; EHK; epidermal keratin 10; epithelial keratin 10; intermediate filament protein; K10; K1C1; Ka10; Ker10; keratin 10; keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris); keratin 10, type I; keratin complex 1, acidic, gene 10; keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 59 kDa; keratin-10; keratin-17; KPP; Krt-1.10; KRT10; krt10 {ECO:0000250; Krt1-10; suprabasal cytokeratin 10; type I keratin KA10; UniProtKB:P13645}
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国