产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ERCC1单克隆抗体(3H11)
目录 :
MA5-13830
规格 :
500微升
价格 :
美国454.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3H11
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 9
参考文献
Liu L, Bai Z, Ma X, Wang T, Yang Y, Zhang Z. Effects of taxol resistance gene 1 expression on the chemosensitivity of SGC-7901 cells to oxaliplatin. Exp Ther Med. 2016;11:846-852 pubmed
Watt H, Rachid Z, Jean Claude B. The Concept of Divergent Targeting through the Activation and Inhibition of Receptors as a Novel Chemotherapeutic Strategy: Signaling Responses to Strong DNA-Reactive Combinatorial Mimicries. J Signal Transduct. 2012;2012:282050 pubmed 出版商
Tomicic M, Reischmann P, Rasenberger B, Meise R, Kaina B, Christmann M. Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity. Cell Mol Life Sci. 2011;68:1785-98 pubmed 出版商
Todorova M, Larroque A, Dauphin Pierre S, Fang Y, Jean Claude B. Subcellular distribution of a fluorescence-labeled combi-molecule designed to block epidermal growth factor receptor tyrosine kinase and damage DNA with a green fluorescent species. Mol Cancer Ther. 2010;9:869-82 pubmed 出版商
Al Minawi A, Lee Y, Håkansson D, Johansson F, Lundin C, Saleh Gohari N, et al. The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links. Nucleic Acids Res. 2009;37:6400-13 pubmed 出版商
Gustavson M, Bourke Martin B, Reilly D, Cregger M, Williams C, Tedeschi G, et al. Development of an unsupervised pixel-based clustering algorithm for compartmentalization of immunohistochemical expression using Automated QUantitative Analysis. Appl Immunohistochem Mol Morphol. 2009;17:329-37 pubmed 出版商
Stordal B, Davey R. ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair. Cancer Chemother Pharmacol. 2009;63:661-72 pubmed 出版商
Guo W, Zhao Y, Jiang Y, Wang R, Hong L, Fan D. ZNRD1 might mediate UV irradiation related DNA damage and repair in human esophageal cancer cells by regulation of ERCC1. Dis Esophagus. 2008;21:730-6 pubmed 出版商
Selvakumaran M, Pisarcik D, Bao R, Yeung A, Hamilton T. Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines. Cancer Res. 2003;63:1311-6 pubmed
产品信息
产品类型 :
抗体
产品名称 :
ERCC1单克隆抗体(3H11)
目录# :
MA5-13830
规格 :
500微升
价格 :
美国454.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunoprecipitation: 2 µg/mL, Western Blot: 1-3 µg/mL
物种 :
人类
克隆 :
3H11
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. (Uniprot)
免疫原 :
全长重组人类ERCC1蛋白
格式 :
液体
应用w/稀释 :
Immunoprecipitation: 2 µg/mL, Western Blot: 1-3 µg/mL
别名 :
COFS4; DNA excision repair protein ERCC-1; ERCC excision repair 1, endonuclease non-catalytic subunit; Ercc1; Ercc-1; excision repair cross-complementation group 1; excision repair cross-complementing 1; excision repair cross-complementing rodent repair deficiency, complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); hypothetical protein LOC405807; RAD10; UV20; zgc:77511
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国