| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
- 免疫组化-石蜡切片; 人类; 1:250; 图 3h
- 免疫印迹; 人类; 1:250; 图 5d
| Moreno Rodríguez M, Perez S, Nadeem M, Malek Ahmadi M, Mufson E. Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer's disease. J Neuroinflammation. 2020;17:58 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 1:100; 图 8i
| Sang Y, Li Y, Zhang Y, Alvarez A, Yu B, Zhang W, et al. CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity. Nat Commun. 2019;10:4013 pubmed 出版商 |
| Chang Y, Lin T, Campbell M, Pan C, Lee S, Lee H, et al. REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer. Sci Rep. 2017;7:42795 pubmed 出版商 |
| Horvatinovich J, Grogan E, Norris M, Steinkasserer A, Lemos H, Mellor A, et al. Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes. J Immunol. 2017;198:2286-2301 pubmed 出版商 |
| Yoo S, Leng L, Kim B, Du X, Tilstam P, Kim K, et al. MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2016;113:E7917-E7926 pubmed |
- 免疫组化-石蜡切片; 人类; 1:800; 图 2b
| Zhao H, Tang H, Xiao Q, He M, Zhao L, Fu Y, et al. The Hedgehog signaling pathway is associated with poor prognosis in breast cancer patients with the CD44+/CD24? phenotype. Mol Med Rep. 2016;14:5261-5270 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 1:100; 图 3a
| Horimoto Y, Arakawa A, Sasahara N, Tanabe M, Sai S, Himuro T, et al. Combination of Cancer Stem Cell Markers CD44 and CD24 Is Superior to ALDH1 as a Prognostic Indicator in Breast Cancer Patients with Distant Metastases. PLoS ONE. 2016;11:e0165253 pubmed 出版商 |
- 免疫细胞化学; 人类; 图 1d
- 免疫印迹; 人类; 图 2b
| Bellerby R, Smith C, Kyme S, Gee J, Gunthert U, Green A, et al. Overexpression of Specific CD44 Isoforms Is Associated with Aggressive Cell Features in Acquired Endocrine Resistance. Front Oncol. 2016;6:145 pubmed 出版商 |
| Seo A, Lee H, Kim E, Jang M, Kim Y, Kim J, et al. Expression of breast cancer stem cell markers as predictors of prognosis and response to trastuzumab in HER2-positive breast cancer. Br J Cancer. 2016;114:1109-16 pubmed 出版商 |
| Lee T, Liu C, Chang Y, Nieh S, Lin Y, Jao S, et al. Increased chemoresistance via Snail-Raf kinase inhibitor protein signaling in colorectal cancer in response to a nicotine derivative. Oncotarget. 2016;7:23512-20 pubmed 出版商 |
| Binmadi N, Elsissi A, Elsissi N. Expression of cell adhesion molecule CD44 in mucoepidermoid carcinoma and its association with the tumor behavior. Head Face Med. 2016;12:8 pubmed 出版商 |
| Shu S, Lin C, He H, Witwicki R, Tabassum D, Roberts J, et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. Nature. 2016;529:413-417 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 1:100; 图 1
| AbdElazeem M, El Sayed M. The pattern of CD44 and matrix metalloproteinase 9 expression is a useful predictor of ulcerative colitis-associated dysplasia and neoplasia. Ann Diagn Pathol. 2015;19:369-74 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 1:100-1:200; 图 2
| Ceyran A, Şenol S, Güzelmeriç F, Tunçer E, Tongut A, Özbek B, et al. Effects of hypoxia and its relationship with apoptosis, stem cells, and angiogenesis on the thymus of children with congenital heart defects: a morphological and immunohistochemical study. Int J Clin Exp Pathol. 2015;8:8038-47 pubmed |
| KapucuoÄŸlu N, Bozkurt K, BaÅŸpınar Å, Koçer M, EroÄŸlu H, Akdeniz R, et al. The clinicopathological and prognostic significance of CD24, CD44, CD133, ALDH1 expressions in invasive ductal carcinoma of the breast: CD44/CD24 expression in breast cancer. Pathol Res Pract. 2015;211:740-7 pubmed 出版商 |
| Sanguinetti A, Santini D, Bonafè M, Taffurelli M, Avenia N. Interleukin-6 and pro inflammatory status in the breast tumor microenvironment. World J Surg Oncol. 2015;13:129 pubmed 出版商 |
| Westcott J, Prechtl A, Maine E, Dang T, Esparza M, Sun H, et al. An epigenetically distinct breast cancer cell subpopulation promotes collective invasion. J Clin Invest. 2015;125:1927-43 pubmed 出版商 |
| Rappa G, Green T, Karbanová J, Corbeil D, Lorico A. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget. 2015;6:7970-91 pubmed |
- 免疫组化-石蜡切片; 人类; 1:2000; 表 2
| Koo D, Lee H, Ahn J, Yoon D, Kim S, Gong G, et al. Tau and PTEN status as predictive markers for response to trastuzumab and paclitaxel in patients with HER2-positive breast cancer. Tumour Biol. 2015;36:5865-71 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 1:200; 图 1
| Kaygusuz E. Immunohistochemical expression of CD44 standard and E-cadherin in atypical leiomyoma and leiomyosarcoma of the uterus. J Obstet Gynaecol. 2015;35:279-82 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 1:200; 表 3
| Gwak J, Kim H, Kim E, Chung Y, Yun S, Seo A, et al. MicroRNA-9 is associated with epithelial-mesenchymal transition, breast cancer stem cell phenotype, and tumor progression in breast cancer. Breast Cancer Res Treat. 2014;147:39-49 pubmed 出版商 |
| He Q, Luo X, Wang K, Zhou Q, Ao H, Yang Y, et al. Isolation and characterization of cancer stem cells from high-grade serous ovarian carcinomas. Cell Physiol Biochem. 2014;33:173-84 pubmed 出版商 |
| Almendro V, Kim H, Cheng Y, Gonen M, Itzkovitz S, Argani P, et al. Genetic and phenotypic diversity in breast tumor metastases. Cancer Res. 2014;74:1338-48 pubmed 出版商 |
| Wu Y, Sarkissyan M, Elshimali Y, Vadgama J. Triple negative breast tumors in African-American and Hispanic/Latina women are high in CD44+, low in CD24+, and have loss of PTEN. PLoS ONE. 2013;8:e78259 pubmed 出版商 |
| Mylona E, Melissaris S, Giannopoulou I, Theohari I, Papadimitriou C, Keramopoulos A, et al. Y-box-binding protein 1 (YB1) in breast carcinomas: relation to aggressive tumor phenotype and identification of patients at high risk for relapse. Eur J Surg Oncol. 2014;40:289-96 pubmed 出版商 |
| Adamczyk A, Niemiec J, Ambicka A, Mucha Małecka A, Mituś J, Rys J. CD44/CD24 as potential prognostic markers in node-positive invasive ductal breast cancer patients treated with adjuvant chemotherapy. J Mol Histol. 2014;45:35-45 pubmed 出版商 |
| Ohara Y, Oda T, Sugano M, Hashimoto S, Enomoto T, Yamada K, et al. Histological and prognostic importance of CD44(+) /CD24(+) /EpCAM(+) expression in clinical pancreatic cancer. Cancer Sci. 2013;104:1127-34 pubmed 出版商 |
- 免疫细胞化学; 人类; 1:200
- 免疫组化; 人类
| Jambal P, Badtke M, Harrell J, Borges V, Post M, Sollender G, et al. Estrogen switches pure mucinous breast cancer to invasive lobular carcinoma with mucinous features. Breast Cancer Res Treat. 2013;137:431-48 pubmed 出版商 |
- 免疫沉淀; 人类
- 免疫细胞化学; 人类
- 免疫印迹; 人类
| Hiscox S, Baruha B, Smith C, Bellerby R, Goddard L, Jordan N, et al. Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan. BMC Cancer. 2012;12:458 pubmed 出版商 |
| Currie M, Beardsley B, Harris G, Gunningham S, Dachs G, Dijkstra B, et al. Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: relationships with markers of tumor hypoxia and microvascularity. Hum Pathol. 2013;44:402-11 pubmed 出版商 |
| Jeong B, Liang Z, Huang S, Lim J, Kim J, Lee H. CD44 is associated with tumor recurrence and is an independent poor prognostic factor for patients with localized clear cell renal cell carcinoma after nephrectomy. Exp Ther Med. 2012;3:811-817 pubmed |
| Tajima H, Ohta T, Kitagawa H, Okamoto K, Sakai S, Kinoshita J, et al. Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increases in situ expression of the apoptosis marker M30 and stem cell marker CD44. Oncol Lett. 2012;3:1186-1190 pubmed |
| Kagara N, Huynh K, Kuo C, Okano H, Sim M, Elashoff D, et al. Epigenetic regulation of cancer stem cell genes in triple-negative breast cancer. Am J Pathol. 2012;181:257-67 pubmed 出版商 |
| Hashimoto K, Shimizu C, Tsuda H, Saji S, Osaki A, Shigekawa T, et al. Immunohistochemical detection of breast cancer stem cells in hormone receptor-positive breast cancer and their role in response to endocrine therapy and clinical outcome. Oncology. 2012;82:168-74 pubmed 出版商 |
| Jung Y, Joo K, Seong D, Choi Y, Kong D, Kim Y, et al. Identification of prognostic biomarkers for glioblastomas using protein expression profiling. Int J Oncol. 2012;40:1122-32 pubmed 出版商 |
| Hou Y, Zou Q, Ge R, Shen F, Wang Y. The critical role of CD133(+)CD44(+/high) tumor cells in hematogenous metastasis of liver cancers. Cell Res. 2012;22:259-72 pubmed 出版商 |
| Marotta L, Almendro V, Marusyk A, Shipitsin M, Schemme J, Walker S, et al. The JAK2/STAT3 signaling pathway is required for growth of CD44?CD24? stem cell-like breast cancer cells in human tumors. J Clin Invest. 2011;121:2723-35 pubmed 出版商 |
| Demirag F, Cakir E, Alpar S, Tastepe I, Kaya S. Expression of CD44 and MMP-2: possible association with histopathological features of pleuro-pulmonary solitary fibrous tumors. Turk Patoloji Derg. 2011;27:127-33 pubmed 出版商 |
| Lee H, Kim J, Kim Y, Choi S, Kim S, Kang E, et al. An increase in cancer stem cell population after primary systemic therapy is a poor prognostic factor in breast cancer. Br J Cancer. 2011;104:1730-8 pubmed 出版商 |
| Ween M, Oehler M, Ricciardelli C. Role of versican, hyaluronan and CD44 in ovarian cancer metastasis. Int J Mol Sci. 2011;12:1009-29 pubmed 出版商 |
- 流式细胞仪; 人类
- 免疫细胞化学; 人类
- 免疫组化; 人类
| Anido J, Sáez Borderías A, Gonzàlez Juncà A, Rodón L, Folch G, Carmona M, et al. TGF-? Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma. Cancer Cell. 2010;18:655-68 pubmed 出版商 |
| Karaoz E, Okçu A, Gacar G, Sağlam O, Yuruker S, Kenar H. A comprehensive characterization study of human bone marrow mscs with an emphasis on molecular and ultrastructural properties. J Cell Physiol. 2011;226:1367-82 pubmed 出版商 |
| Balic M, Rapp N, Stanzer S, Lin H, Strutz J, Szkandera J, et al. Novel immunofluorescence protocol for multimarker assessment of putative disseminating breast cancer stem cells. Appl Immunohistochem Mol Morphol. 2011;19:33-40 pubmed 出版商 |
| Kawasaki H, Ogura H, Arai Y, Baba S, Kosugi I, Tsutsui Y, et al. Aggressive progression of breast cancer with microscopic pulmonary emboli possessing a stem cell-like phenotype independent of its origin. Pathol Int. 2010;60:228-34 pubmed 出版商 |
| Seegmiller A, Garcia R, Huang R, Maleki A, Karandikar N, Chen W. Simple karyotype and bcl-6 expression predict a diagnosis of Burkitt lymphoma and better survival in IG-MYC rearranged high-grade B-cell lymphomas. Mod Pathol. 2010;23:909-20 pubmed 出版商 |
| Park S, Gonen M, Kim H, Michor F, Polyak K. Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. J Clin Invest. 2010;120:636-44 pubmed 出版商 |
| Gunia S, May M, Koch S, Dietel M, Erbersdobler A. Expression of CD44s in incidental prostate cancer is more strongly associated with Gleason scores on subsequent radical prostatectomies than conventional prognostic parameters. Pathobiology. 2009;76:286-92 pubmed 出版商 |
| Bogusz A, Seegmiller A, Garcia R, Shang P, Ashfaq R, Chen W. Plasmablastic lymphomas with MYC/IgH rearrangement: report of three cases and review of the literature. Am J Clin Pathol. 2009;132:597-605 pubmed 出版商 |
- 免疫细胞化学; 人类; 1:1000
- 免疫印迹; 人类; 1:2000
| Dittmer A, Hohlfeld K, Lützkendorf J, Müller L, Dittmer J. Human mesenchymal stem cells induce E-cadherin degradation in breast carcinoma spheroids by activating ADAM10. Cell Mol Life Sci. 2009;66:3053-65 pubmed 出版商 |
| Hong S, Wen J, Bang S, Park S, Song S. CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells. Int J Cancer. 2009;125:2323-31 pubmed 出版商 |
| Tanei T, Morimoto K, Shimazu K, Kim S, Tanji Y, Taguchi T, et al. Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers. Clin Cancer Res. 2009;15:4234-41 pubmed 出版商 |
| Snyder E, Bailey D, Shipitsin M, Polyak K, Loda M. Identification of CD44v6(+)/CD24- breast carcinoma cells in primary human tumors by quantum dot-conjugated antibodies. Lab Invest. 2009;89:857-66 pubmed 出版商 |
| Nakajima K, Abe T, Tanaka M, Hara Y. Periodontal tissue engineering by transplantation of multilayered sheets of phenotypically modified gingival fibroblasts. J Periodontal Res. 2008;43:681-8 pubmed 出版商 |
| Honeth G, Bendahl P, Ringner M, Saal L, Gruvberger Saal S, Lövgren K, et al. The CD44+/CD24- phenotype is enriched in basal-like breast tumors. Breast Cancer Res. 2008;10:R53 pubmed 出版商 |
| Mylona E, Giannopoulou I, Fasomytakis E, Nomikos A, Magkou C, Bakarakos P, et al. The clinicopathologic and prognostic significance of CD44+/CD24(-/low) and CD44-/CD24+ tumor cells in invasive breast carcinomas. Hum Pathol. 2008;39:1096-102 pubmed 出版商 |
| Paupert J, Mansat De Mas V, Demur C, Salles B, Muller C. Cell-surface MMP-9 regulates the invasive capacity of leukemia blast cells with monocytic features. Cell Cycle. 2008;7:1047-53 pubmed |
| Horwitz K, Dye W, Harrell J, Kabos P, Sartorius C. Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proc Natl Acad Sci U S A. 2008;105:5774-9 pubmed 出版商 |
| Sansone P, Storci G, Tavolari S, Guarnieri T, Giovannini C, Taffurelli M, et al. IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland. J Clin Invest. 2007;117:3988-4002 pubmed |
| Harrell J, Dye W, Harvell D, Pinto M, Jedlicka P, Sartorius C, et al. Estrogen insensitivity in a model of estrogen receptor positive breast cancer lymph node metastasis. Cancer Res. 2007;67:10582-91 pubmed |
| Charafe Jauffret E, Monville F, Bertucci F, Esterni B, Ginestier C, Finetti P, et al. Moesin expression is a marker of basal breast carcinomas. Int J Cancer. 2007;121:1779-85 pubmed |
| Ricciardelli C, Russell D, Ween M, Mayne K, Suwiwat S, Byers S, et al. Formation of hyaluronan- and versican-rich pericellular matrix by prostate cancer cells promotes cell motility. J Biol Chem. 2007;282:10814-25 pubmed |
| Balic M, Lin H, Young L, Hawes D, Giuliano A, McNamara G, et al. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin Cancer Res. 2006;12:5615-21 pubmed |
| Kuo K, Liang C, Hsiao C, Lin C, Chen C, Sheu B, et al. Downregulation of BRG-1 repressed expression of CD44s in cervical neuroendocrine carcinoma and adenocarcinoma. Mod Pathol. 2006;19:1570-7 pubmed |
| Harrell J, Dye W, Allred D, Jedlicka P, Spoelstra N, Sartorius C, et al. Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes. Cancer Res. 2006;66:9308-15 pubmed |
- 免疫细胞化学; 人类; 1 ug/ml
- 免疫组化; 人类
| Zhuo L, Kanamori A, Kannagi R, Itano N, Wu J, Hamaguchi M, et al. SHAP potentiates the CD44-mediated leukocyte adhesion to the hyaluronan substratum. J Biol Chem. 2006;281:20303-14 pubmed |
| Lo H, Xia W, Wei Y, Ali Seyed M, Huang S, Hung M. Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer. Cancer Res. 2005;65:338-48 pubmed |
| Voeltzel T, Fossard G, Degaud M, Geistlich K, Gadot N, Jeanpierre S, et al. A minimal standardized human bone marrow microphysiological system to assess resident cell behavior during normal and pathological processes. Biomater Sci. 2022;10:485-498 pubmed 出版商 |
| Lee E, Lokman N, Oehler M, Ricciardelli C, Grützner F. A Comprehensive Molecular and Clinical Analysis of the piRNA Pathway Genes in Ovarian Cancer. Cancers (Basel). 2020;13: pubmed 出版商 |
| Kawaguchi M, Dashzeveg N, Cao Y, Jia Y, Liu X, Shen Y, et al. Extracellular Domains I and II of cell-surface glycoprotein CD44 mediate its trans-homophilic dimerization and tumor cluster aggregation. J Biol Chem. 2020;295:2640-2649 pubmed 出版商 |
| Verigos J, Karakaidos P, Kordias D, Papoudou Bai A, Evangelou Z, Harissis H, et al. The Histone Demethylase LSD1/ΚDM1A Mediates Chemoresistance in Breast Cancer via Regulation of a Stem Cell Program. Cancers (Basel). 2019;11: pubmed 出版商 |
| Yuk H, Jeong C, Kwak C, Kim H, Moon K, Ku J. Clinical outcomes of muscle invasive bladder Cancer according to the BASQ classification. BMC Cancer. 2019;19:897 pubmed 出版商 |
| Wang M, Nagle R, Knudsen B, Cress A, Rogers G. Centrosome loss results in an unstable genome and malignant prostate tumors. Oncogene. 2019;: pubmed 出版商 |
| Hellman U, Engström Laurent A, Larsson A, Lindqvist U. Hyaluronan concentration and molecular mass in psoriatic arthritis: biomarkers of disease severity, resistance to treatment, and outcome. Scand J Rheumatol. 2019;48:284-293 pubmed 出版商 |
| Holm A, Hellman U, Laurent C, Laurell G, Nylander K, Olofsson K. Hyaluronan in vocal folds and false vocal folds in patients with recurrent respiratory papillomatosis. Acta Otolaryngol. 2018;138:1020-1027 pubmed 出版商 |
| Liao S, Gan L, Qin W, Liu C, Mei Z. Inhibition of GSK3 and MEK induced cancer stem cell generation via the Wnt and MEK signaling pathways. Oncol Rep. 2018;40:2005-2013 pubmed 出版商 |
| Kowtharapu B, Murin R, Jünemann A, Stachs O. Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing. Int J Mol Sci. 2018;19: pubmed 出版商 |
| Freedland S, Seligson D, Liu A, Pantuck A, Paik S, Horvath S, et al. Loss of CD10 (neutral endopeptidase) is a frequent and early event in human prostate cancer. Prostate. 2003;55:71-80 pubmed |
