产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD10单克隆抗体(56C6)
目录 :
MA5-14050
规格 :
500微升
价格 :
美国446.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
56C6
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 64
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:10; 图 3a
Leo F, Bartels S, Mägel L, Framke T, Büsche G, Jonigk D, et al. Prognostic factors in the myoepithelial-like spindle cell type of metaplastic breast cancer. Virchows Arch. 2016;469:191-201 pubmed 出版商
  • 免疫组化; 人类; 1:50; 表 1
Kim Y, Lee S, Kim J, Sung I, Park H, Shim C, et al. Microsatellite Instability of Gastric and Colorectal Cancers as a Predictor of Synchronous Gastric or Colorectal Neoplasms. Gut Liver. 2016;10:220-7 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:20; 图 s5
Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, et al. Epigenetic and transcriptional determinants of the human breast. Nat Commun. 2015;6:6351 pubmed 出版商
  • 免疫组化; 人类; 1:200
Song M, Chung J, Lee G, Cho S, Hong J, Shin D, et al. Statin use has negative clinical impact on non-germinal center in patients with diffuse large B cell lymphoma in rituximab era. Leuk Res. 2015;39:211-5 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Song M, Chung J, Lee J, Yang D, Kim I, Shin D, et al. High Ki-67 expression in involved bone marrow predicts worse clinical outcome in diffuse large B cell lymphoma patients treated with R-CHOP therapy. Int J Hematol. 2015;101:140-7 pubmed 出版商
  • 免疫组化; 人类
Kraan W, Horlings H, Van Keimpema M, Schilder Tol E, Oud M, Scheepstra C, et al. High prevalence of oncogenic MYD88 and CD79B mutations in diffuse large B-cell lymphomas presenting at immune-privileged sites. Blood Cancer J. 2013;3:e139 pubmed 出版商
  • 免疫组化; 人类; 1:50
Park H, Lee S, Hong S, Kim J, Sung I, Park H, et al. Early Gastric Cancer-Like Advanced Gastric Cancer versus Advanced Gastric Cancer-Like Early Gastric Cancer. Clin Endosc. 2013;46:155-60 pubmed 出版商
  • 免疫组化; 人类; 1:30
Ho M, Quek S, True L, Morrissey C, Corey E, Vessella R, et al. Prostate cancer cell phenotypes based on AGR2 and CD10 expression. Mod Pathol. 2013;26:849-59 pubmed 出版商
  • 免疫组化; 人类
Hasby E, Saad H. Immunohistochemical expression of Fas ligand (FasL) and neprilysin (neutral endopeptidase/CD10) in keratoconus. Int Ophthalmol. 2013;33:125-31 pubmed 出版商
  • 免疫组化; 人类; 1:10
Romeo S, Bovee J, Kroon H, Tirabosco R, Natali C, Zanatta L, et al. Malignant fibrous histiocytoma and fibrosarcoma of bone: a re-assessment in the light of currently employed morphological, immunohistochemical and molecular approaches. Virchows Arch. 2012;461:561-70 pubmed 出版商
  • 免疫组化; 人类; 1:50
Lee H, Lee S, Yoon H, Hong S, Kim J, Sung I, et al. Change of mucosal color in early gastric cancer. J Dig Dis. 2012;13:510-6 pubmed 出版商
  • 免疫组化; 人类; 1:50
Yin W, Li J, Chan J. Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review. Diagn Pathol. 2012;7:39 pubmed 出版商
  • 免疫组化; 人类; 1:20
Deniz K, Coban G, Okten T. Anti-CD10 (56C6) expression in soft tissue sarcomas. Pathol Res Pract. 2012;208:281-5 pubmed 出版商
  • 免疫组化; 人类
Yigit S, Pehlivan F, Evcim G, Etit D. Clinicopathologic features of the mixed epithelial and mesenchymal type metaplastic breast carcinoma with myoepithelial differentiation in a subset of six cases. Pathol Res Pract. 2012;208:147-50 pubmed 出版商
  • 免疫组化; 人类; 1:30
Cardinalli I, de Oliveira Filho A, Mastellaro M, Ribeiro R, Aguiar S. A unique case of synchronous functional adrenocortical adenoma and myelolipoma within the ectopic adrenal cortex in a child with Beckwith-Wiedemann syndrome. Pathol Res Pract. 2012;208:189-94 pubmed 出版商
  • 免疫组化; 人类; 1:20
Castillo J, Beltran B, Song M, Ilic I, Leppa S, Nurmi H, et al. The Hans algorithm is not prognostic in patients with diffuse large B-cell lymphoma treated with R-CHOP. Leuk Res. 2012;36:413-7 pubmed 出版商
  • 免疫组化; 人类; 1:100
Yu G, Kong L, Qu G, Zhang Q, Wang W, Jiang L. Composite lymphoma in the anterior mediastinum: a case report and review of the literature. Diagn Pathol. 2011;6:60 pubmed 出版商
  • 免疫组化; 人类; 1:50
Demirkesen C, Tuzuner N, Esen T, Lebe B, Ozkal S. The expression of IgM is helpful in the differentiation of primary cutaneous diffuse large B cell lymphoma and follicle center lymphoma. Leuk Res. 2011;35:1269-72 pubmed 出版商
  • 免疫组化; 人类
Masloub S, Abdel Azim A, Elhamid E. CD10 and osteopontin expression in dentigerous cyst and ameloblastoma. Diagn Pathol. 2011;6:44 pubmed 出版商
  • 免疫组化; 人类; 1:20
Clay M, Gibson P, Lowell J, Cooper K. Microscopic uterine lymphangioleiomyomatosis perivascular epithelioid cell neoplasm: a case report with the earliest manifestation of this enigmatic neoplasm. Int J Gynecol Pathol. 2011;30:71-5 pubmed 出版商
  • 免疫组化; 人类; 1:100
Yu G, Qu G, Kong L, Pan X, Wang W, Lv J. Primary myoepithelial carcinoma of the larynx: case report and review of the literature. Pathol Res Pract. 2011;207:127-30 pubmed 出版商
  • 免疫组化; 人类
Mansoor A, Pittaluga S, Beck P, Wilson W, Ferry J, Jaffe E. NK-cell enteropathy: a benign NK-cell lymphoproliferative disease mimicking intestinal lymphoma: clinicopathologic features and follow-up in a unique case series. Blood. 2011;117:1447-52 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:10; 图 1, 2, 3
  • 免疫组化; 人类; 1:10
Cheuk W, Tam F, Chan A, Luk I, Yuen A, Chan W, et al. Idiopathic cervical fibrosis--a new member of IgG4-related sclerosing diseases: report of 4 cases, 1 complicated by composite lymphoma. Am J Surg Pathol. 2010;34:1678-85 pubmed 出版商
  • 免疫组化; 人类
Pozdzik A, Berton A, Schmeiser H, Missoum W, Decaestecker C, Salmon I, et al. Aristolochic acid nephropathy revisited: a place for innate and adaptive immunity?. Histopathology. 2010;56:449-63 pubmed 出版商
  • 免疫组化; 人类; 1:200
Song M, Chung J, Sung Yong O, Lee G, Kim S, Seol Y, et al. Clinical impact of bulky mass in the patient with primary extranodal diffuse large B cell lymphoma treated with R-CHOP therapy. Ann Hematol. 2010;89:985-91 pubmed 出版商
  • 免疫组化; 人类; 1:200
Song M, Chung J, Seol Y, Kim S, Shin H, Choi Y, et al. Influence of low absolute lymphocyte count of patients with nongerminal center type diffuse large B-cell lymphoma with R-CHOP therapy. Ann Oncol. 2010;21:140-4 pubmed 出版商
  • 免疫组化; 人类; 1:60
Chang I, Huang H, Sung M. Melanotic Xp11 translocation renal cancer: a case with PSF-TFE3 gene fusion and up-regulation of melanogenetic transcripts. Am J Surg Pathol. 2009;33:1894-901 pubmed 出版商
  • 免疫组化; 人类; 1:50
Neves C, Soares A, Costa A, de Araujo V, Furuse C, Juliano P, et al. CD10 (Neutral Endopeptidase) Expression in Myoepithelial Cells of Salivary Neoplasms. Appl Immunohistochem Mol Morphol. 2010;18:172-8 pubmed 出版商
  • 免疫组化; 人类; 1:10
Cheuk W, Lee K, Chong L, Yuen S, Chan J. IgG4-related Sclerosing disease: a potential new etiology of cutaneous pseudolymphoma. Am J Surg Pathol. 2009;33:1713-9 pubmed 出版商
  • 免疫组化; 人类
Dunphy C, O Malley D, Cheng L, Fodrie T, Perkins S, Kaiser Rogers K. Primary mediastinal B-cell lymphoma: detection of BCL2 gene rearrangements by PCR analysis and FISH. J Hematop. 2008;1:77-84 pubmed 出版商
  • 免疫组化; 人类
Rys J, Karolewski K, Pudełek J, Kruczak A, Wasilewska A, Vogelgesang M, et al. Perivascular epithelioid tumor (PEComa) of the falciform/ broad ligament. Pol J Pathol. 2008;59:211-5 pubmed
  • 免疫组化; 人类; 1:40
Alacacioglu I, Ozcan M, Ozkal S, Piskin O, Turgut N, Demirkan F, et al. Prognostic significance of immunohistochemical classification of diffuse large B-cell lymphoma. Hematology. 2009;14:84-9 pubmed 出版商
  • 免疫组化; 人类; 1:50
Gao H, Ho J, Lee H, Yu C. The presence of Merkel cells and CD10- and CD34-positive stromal cells compared in benign and malignant oral tumors. Oral Dis. 2009;15:259-64 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200
  • 免疫印迹; 人类; 1:100
Wang R, Wang S, Malter J, Wang D. Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells. J Neurochem. 2009;108:1072-82 pubmed 出版商
  • 免疫组化; 人类; 1:50
Han H, Lee S, Lee K, Hong S, Kim J, Sung I, et al. Unclassified mucin phenotype of gastric adenocarcinoma exhibits the highest invasiveness. J Gastroenterol Hepatol. 2009;24:658-66 pubmed 出版商
  • 免疫组化; 人类; 1:60
Kelten C, Kabukcu S, Sen N, Teke Z, Yaren A, Erdem E, et al. Secondary involvement of the breast in T-cell non-Hodgkin lymphoma, an unusual example mimicking inflammatory breast carcinoma. Arch Gynecol Obstet. 2009;280:149-52 pubmed 出版商
  • 免疫组化; 人类
Yegen G, Demir M, Ertan Y, Nalbant O, Tuncyurek M. Can CD10 be used as a diagnostic marker in thyroid pathology?. Virchows Arch. 2009;454:101-5 pubmed 出版商
  • 免疫组化; 人类; 1:20
Barisella M, Lampis A, Perrone F, Carbone A. Clear cell adenocarcinoma of the colon is a unique morphological variant of intestinal carcinoma: case report with molecular analysis. World J Gastroenterol. 2008;14:6575-7 pubmed
  • 免疫组化; 大鼠; 1:60
Esendagli G, Yilmaz G, Canpinar H, Gunel Ozcan A, Guc M, Guc D. Coexistence of different tissue tumourigenesis in an N-methyl-N-nitrosourea-induced mammary carcinoma model: a histopathological report in Sprague-Dawley rats. Lab Anim. 2009;43:60-4 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Bukowska A, Lendeckel U, Krohn A, Keilhoff G, Ten Have S, Neumann K, et al. Atrial fibrillation down-regulates renal neutral endopeptidase expression and induces profibrotic pathways in the kidney. Europace. 2008;10:1212-7 pubmed 出版商
  • 免疫组化; 人类; 1:30
Chong Y, Shin J, Cho M, Cui Y, Kim H, Park K. Synchronous primary gastric mantle cell lymphoma and early gastric carcinoma: a case report. Pathol Res Pract. 2008;204:407-11 pubmed 出版商
  • 免疫细胞化学; 人类; 1:80
Ahuja A, Gupta N, Kalra N, Srinivasan R, Chawla Y, Rajwanshi A. Role of CD10 immunochemistry in differentiating hepatocellular carcinoma from metastatic carcinoma of the liver. Cytopathology. 2008;19:229-35 pubmed
  • 免疫组化; 人类; 1:50
Costache M, Simionescu O, Sajin M, Chefani A. Cutaneous metastases carcinoma. Case report and pathological considerations. Rom J Morphol Embryol. 2007;48:177-80 pubmed
  • 免疫组化-石蜡切片; 人类; 1:20
Cheuk W, Chan J, Nuovo G, Chan M, Fok M. Regression of gastric large B-Cell lymphoma accompanied by a florid lymphoma-like T-cell reaction: immunomodulatory effect of Ganoderma lucidum (Lingzhi)?. Int J Surg Pathol. 2007;15:180-6 pubmed
  • 免疫细胞化学; 人类; 1:30
Bircan S, Candir O, Kapucuoglu N, Serel T, Ciris M, Karahan N. CD10 expression in urothelial bladder carcinomas: a pilot study. Urol Int. 2006;77:107-13 pubmed
  • 免疫组化; 小鼠
Li S, Chang S, Qi X, Richardson J, Olson E. Requirement of a myocardin-related transcription factor for development of mammary myoepithelial cells. Mol Cell Biol. 2006;26:5797-808 pubmed
  • 免疫组化; 人类; 1:40
Koren J, Mensikova J, Mukensnabl P, Zamecnik M. Mullerianosis of the urinary bladder: report of a case with suggested metaplastic origin. Virchows Arch. 2006;449:268-71 pubmed
  • 免疫组化; 人类; 1:50
de Araujo V, Altemani A, Furuse C, Martins M, de Araujo N. Immunoprofile of reactive salivary myoepithelial cells in intraductal areas of carcinoma ex-pleomorphic adenoma. Oral Oncol. 2006;42:1011-6 pubmed
  • 免疫组化; 人类; 1:50
Butnor K, Nicholson A, Allred D, Zander D, Henderson D, Barrios R, et al. Expression of renal cell carcinoma-associated markers erythropoietin, CD10, and renal cell carcinoma marker in diffuse malignant mesothelioma and metastatic renal cell carcinoma. Arch Pathol Lab Med. 2006;130:823-7 pubmed
  • 免疫组化; 人类; 1:15
Braham H, Trimeche M, Ziadi S, Mestiri S, Mokni M, Amara K, et al. CD10 expression by fusiform stromal cells in nasopharyngeal carcinoma correlates with tumor progression. Virchows Arch. 2006;449:220-4 pubmed
  • 免疫组化; 人类
Zamecnik M, Skrivanek A. Adenoid basal epithelioma of the uterine cervix in 21-year-old patient. Report of a case with histologic and immunohistochemical study. Cesk Patol. 2005;41:157-62 pubmed
  • 免疫印迹; 小鼠
Hass M, Yankner B. A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein. J Biol Chem. 2005;280:36895-904 pubmed
Astarci H, Gurbuz G, Sengul D, Hucumenoglu S, Kocer U, Ustun H. Significance of androgen receptor and CD10 expression in cutaneous basal cell carcinoma and trichoepithelioma. Oncol Lett. 2015;10:3466-3470 pubmed
Sauter J, Ambaye A, Mount S. Increased utilization, verification, and clinical implications of immunocytochemistry: Experience in a northern New England hospital. Diagn Cytopathol. 2015;43:688-95 pubmed 出版商
Grimaldi A, Tettamanti G, Congiu T, Girardello R, Malagoli D, Falabella P, et al. The main actors involved in parasitization of Heliothis virescens larva. Cell Tissue Res. 2012;350:491-502 pubmed 出版商
Reynolds G, Harris H, Jennings A, Hu K, Grove J, Lalor P, et al. Hepatitis C virus receptor expression in normal and diseased liver tissue. Hepatology. 2008;47:418-27 pubmed
Cho N, Kim S, Ha M, Kim H. Simultaneous heterogenotypic renal cell carcinoma: immunohistochemical and karyoptic analysis by comparative genomic hybridization. Urol Int. 2004;72:344-8 pubmed
Aust S, Obrist P, Jaeger W, Klimpfinger M, Tucek G, Wrba F, et al. Subcellular localization of the ABCG2 transporter in normal and malignant human gallbladder epithelium. Lab Invest. 2004;84:1024-36 pubmed
Song J, Aumüller G, Xiao F, Wilhelm B, Albrecht M. Cell specific expression of CD10/neutral endopeptidase 24.11 gene in human prostatic tissue and cells. Prostate. 2004;58:394-405 pubmed
Antmen B, Haytac M, Sasmaz I, Dogan M, Ergin M, Tanyeli A. Granulocytic sarcoma of gingiva: an unusual case with aleukemic presentation. J Periodontol. 2003;74:1514-9 pubmed
Albrecht M, Mittler A, Wilhelm B, Lundwall A, Lilja H, Aumüller G, et al. Expression and immunolocalisation of neutral endopeptidase in prostate cancer. Eur Urol. 2003;44:415-22 pubmed
Popnikolov N, Ayala A, Graves K, Gatalica Z. Benign myoepithelial tumors of the breast have immunophenotypic characteristics similar to metaplastic matrix-producing and spindle cell carcinomas. Am J Clin Pathol. 2003;120:161-7 pubmed
Freedland S, Seligson D, Liu A, Pantuck A, Paik S, Horvath S, et al. Loss of CD10 (neutral endopeptidase) is a frequent and early event in human prostate cancer. Prostate. 2003;55:71-80 pubmed
Carpenter T, Stenmark K. Hypoxia decreases lung neprilysin expression and increases pulmonary vascular leak. Am J Physiol Lung Cell Mol Physiol. 2001;281:L941-8 pubmed
图像
图像 1 :
赛默飞世尔 MA5-14050 图像 1
Formalin-fixed, paraffin-embedded rat small intestine stained with CD10 antibody using peroxidase-conjugate and DAB chromogen. Note surface staining of epithelial cells.
图像 2 :
赛默飞世尔 MA5-14050 图像 2
图像 3 :
赛默飞世尔 MA5-14050 图像 3
Formalin-fixed, paraffin-embedded human small intestine stained with CD10 antibody using peroxidase-conjugate and DAB chromogen. Note surface staining of epithelial cells.
产品信息
产品类型 :
抗体
产品名称 :
CD10单克隆抗体(56C6)
目录# :
MA5-14050
规格 :
500微升
价格 :
美国446.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:30-1:60, Western Blot: 1:20-1:200
物种 :
人类, 小鼠, 大鼠
克隆 :
56C6
抗体亚型 :
IgG1
储存 :
4° C
描述 :
CD10 (Common Acute Lymphocytic Leukemia Antigen, CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. CD10 is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. Further, CD10 is a 100 kDa type II transmembrane glycoprotein that exists in a single copy of greater than 45 kb. The 5' untranslated region of the CD10 gene is alternatively spliced, resulting in four separate mRNA transcripts and the coding region is not affected by alternative splicing. Diseases associated with CD10 dysfunction include spinocerebellar ataxia 43 and Charcot-Marie tooth Disease.
免疫原 :
Recombinant external domain of CD10 protein
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:30-1:60, Western Blot: 1:20-1:200
别名 :
6030454K05Rik; Atriopeptidase; C85356; CALLA; CD10; CMT2T; common acute lymphoblastic leukemia antigen; common acute lymphocytic leukemia antigen; Enkephalinase; EPN; membrane metallo endopeptidase; membrane metalloendopeptidase; membrane metallo-endopeptidase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; MME; NEP; neprilysin; neprilysin-390; neprilysin-411; neutral endopeptidase 24.11; SFE; Skin fibroblast elastase
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国