产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
粘蛋白1单克隆抗体(E29)
目录 :
MA5-14077
规格 :
500微升
价格 :
美国351.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
E29
反应物种 :
人类
应用 :
免疫组化, 免疫组化-石蜡切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 22
出版应用/物种/样本/稀释 | 参考文献 |
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| Sajin M, Luchian M, Hodorogea Prisăcaru A, Dumitru A, Pătraşcu O, Costache D, et al. Trichilemmal carcinoma - a rare cutaneous malignancy: report of two cases. Rom J Morphol Embryol. 2014;55:687-91 pubmed
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| Gurbuz Y, Kose N, Aydin O, Ozturk M. An immunohistochemical profile of giant cell carcinoma of the larynx. Auris Nasus Larynx. 2007;34:413-6 pubmed
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| Doi M, Yokoyama A, Kondo K, Ohnishi H, Ishikawa N, Hattori N, et al. Anti-tumor effect of the anti-KL-6/MUC1 monoclonal antibody through exposure of surface molecules by MUC1 capping. Cancer Sci. 2006;97:420-9 pubmed
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| Bikmaz K, Cosar M, Kurtkaya Yapicier O, Iplikcioglu A, Gokduman C. Recurrent solitary fibrous tumour in the cerebellopontine angle. J Clin Neurosci. 2005;12:829-32 pubmed
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Dagli M, Eryilmaz A, Acar A, Kulacoglu S, Akmansu H. Collagenous fibroma (desmoplastic fibroblastoma). Yonsei Med J. 2004;45:941-3 pubmed
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Kocer B, Soran A, Kiyak G, Erdogan S, Eroglu A, Bozkurt B, et al. Prognostic significance of mucin expression in gastric carcinoma. Dig Dis Sci. 2004;49:954-64 pubmed
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Kocer B, Ulas M, Ustundag Y, Erdogan S, Karabeyoglu M, Yldrm O, et al. A confirmatory report for the close interaction of Helicobacter pylori with gastric epithelial MUC5AC expression. J Clin Gastroenterol. 2004;38:496-502 pubmed
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Liu B, Lague J, Nunes D, Toselli P, Oppenheim F, Soares R, et al. Expression of membrane-associated mucins MUC1 and MUC4 in major human salivary glands. J Histochem Cytochem. 2002;50:811-20 pubmed
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图像
图像 1 :
Formalin-fixed, paraffin-embedded human breast carcinoma stained with EMA antibody using peroxidase-conjugate and AEC chromogen. Note membrane and cytoplasmic staining of tumor cells.
产品信息
产品类型 :
抗体
产品名称 :
粘蛋白1单克隆抗体(E29)
目录# :
MA5-14077
规格 :
500微升
价格 :
美国351.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
免疫组化(石蜡): 1:400-1:800
物种 :
人类
克隆 :
E29
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
MUC1 (Mucin 1, Episialin, MAM-6, CA 15-3, PEM and EMA) is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. MUC1 is a transmembrane glycoprotein with a large mucin-like extracellular domain that matures through several intermediate forms generated by proteolysis, and sequential addition and processing of numerous O-linked glycans that are heavily sialylated. MUC1 is highly polymorphic and each allele encodes a product that contains a different number of repeats (between 30 and 90) leading to large differences in molecular weight of the protein. MUC1 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells, and is expressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. Overexpression, aberrant intracellular localization, and changes in glycosylation of the MUC1 protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of the MUC1 gene have been reported, but the full-length nature of only some has been determined. Transgenic MUC-1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands.
免疫原 :
Delipidated extract of human milk fat globule membranes
格式 :
液体
应用w/稀释 :
免疫组化(石蜡): 1:400-1:800
别名 :
ADMCKD; ADMCKD1; Breast carcinoma-associated antigen DF3; CA 15-3; Cancer antigen 15-3; carcinoma-associated mucin; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; J19; KL-6; Krebs von den Lungen-6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease, autosomal dominant; Muc1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin1; mucin-1; Mucin-1 subunit alpha; Mucin-1 subunit beta; peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; tumor-associated epithelial membrane antigen; Tumor-associated mucin
更多信息或购买 :
公司信息
赛默飞世尔